黨永岩

黨永岩，女，華東師範大學生命科學學院副教授、碩士生導師。

基本介紹

• 中文名：黨永岩
• 職業：教師
• 專業方向：腫瘤發生髮展的信號機制研究等
• 任職院校：華東師範大學生命科學學院

研究方向

1. 腫瘤發生髮展的信號機制研究

2. 幹細胞與腫瘤和衰老的關係

3. 各種皮膚疾病的機理研究

主講課程

《生物化學》

學術成果

代表性論文

1.Wang Q, Gao X, Yu T, Yuan L, Dai J, WangW, Chen G, Jiao C, Zhou W, Huang Q, Cui L, Zhang P, Moses RE, Yang J, Chen F,Fu J, Xiao J, Li L, Dang Y, Li X.REGγ Controls Hippo Signaling and Reciprocal NF-κB-YAP Regulation toPromote Colon Cancer. Clinical Cancer Research 2018

2.Li L,Dang Y, Zhang J, et al. REGγis critical for skin carcinogenesis by modulating the Wnt/β- catenin pathway.Nature Communications 2015

3.Xu P, Dang Y, Wang L, Liu X, Ren X, Gu J, Liu M, Dai X, Ye X.Lgr4 is crucial for skin carcinogenesis by regulating MEK/ERK and Wnt/β-catenin signaling pathways.Cancer Lett. 2016

4.Zhai Y,Dang Y, Gao W, Zhang Y, Xu P, Gu J, Ye X.P38 and JNK signal pathways are involved in the regulation of phlorizin against UVB-induced skin damage.Experimental Dermatol 2015

5.Li K, Guo Q, Yang J, Chen H, Hu K, Zhao J, Zheng S, Pang X, Zhou S, Dang Y, Li L.FOXD3 is a tumor suppressor of colon cancer by inhibiting EGFR-Ras-Raf-MEK-ERK signal pathway.Oncotarget 2017

6.Yang X, Li L, Huang Q, Xu W, Cai X, Zhang J, Yan W, Song D, Liu T, Zhou W, Li Z, Yang C,Dang Y*, Xiao J*. Wnt signaling through Snail1 and Zeb1 regulates bone metastasis in lung cancer.American Journal of Cancer Research 2015

7.Chen H, Gao X, Sun Z, Wang Q, Zuo D, Pan L, Li K, Chen J, Chen G, Hu K, Li K, Shah AS, Huang T, Muhammad Zeeshan B, Tong L, Jiao C, Liu J, Chen T, Yao L, Dang Y(*), Liu T(*), Li L(*). REGγ accelerates melanoma formation by regulating Wnt/β-catenin signalling pathway. Experimental Dermatology, 2017

8.Dang Yongyan, Liu Bei, Xu Peng, Zhu Pingya, Ye Xiyun, Liu Mingyao. Gpr48 deficiency induces polycystic kidney lesions and renal fibrosis in mice by activating Wnt signal pathway.Plos ONE 2014

9.Xiyun Ye, Luyang Wang,Yongyan Dang*, Bei Liu, Di Zhao. Investigation of the 1064nm Q-switched Nd:YAG laser on collagen expression in an animal model. Photomedicine and Laser Surgery 2012.

10.Qin Y, Qin X, Xu P, Zhi Y, Xia W, Dang Y(*), Gu J(*), Ye X(*). Potential role of S100A8 in skin rejuvenation with the 1064-nm Q-switched Nd:YAG laser.Lasers Med Sci 2018

11.Ren X, Ge M, Qin X, Xu P, Zhu P,Dang Y*, Gu J, Ye X.S100a8/NF-κB signal pathway is involved in the 800-nm diode laser-induced skin collagen remodeling. Lasers Med Sci. 2016

12.Li Lei，Zhao D, Wei H, Yao L,Dang Y, Amjad A,et al. REGγ deficiency promotes premature aging via the casein kinase 1 pathway. PNAS; 2013.

主持項目

SME3在未分化甲狀腺癌發生髮展中的作用和分子機制——國家自然科學基金青年項目

PA28γ通過Hippo-YAP信號通路參與結腸癌的分子機制——上海市自然科學基金項目

PA28 gamma在皮膚鱗狀癌發生髮展中的作用和分子機制——上海市自然科學基金項目

PA28 gamma參與髓樣甲狀腺癌致病的實驗研究——教育部博士點專項基金項目