黃成鋼，中科院上海藥物所研究員、博士生導師、研究組長、中藥現代研究中心副主任。
基本介紹
- 中文名：黃成鋼
- 國籍：中國
- 職業：中科院上海藥物所研究員
- 畢業院校：桂林醫學院，黑龍江中醫藥大學，浙江大學
- 主要成就：多年從事中藥及複方的基礎研究和新藥開發
- 研究方向：現代中藥研究開發
概述,研究方向,專家類別,職務,承擔科研項目情況,代表論著,
概述
1981 年畢業於桂林醫學院藥學系，
1989 年碩士畢業於黑龍江中醫藥大學中藥系，
1998 年博士畢業於浙江大學化學系，
2000 年中國科學院上海藥物研究所博士後出站留所工作。
研究方向
中藥複方藥效物質基礎及作用機理研究，現代中藥研究開發
專家類別
職務
中科院上海藥物所研究員、博士生導師、研究組長、中藥現代研究中心副主任
承擔科研項目情況
多年從事中藥及複方的基礎研究和新藥開發。採用體內多成分分析等先進方法研究中藥及複方藥效物質基礎，特別是口服後吸收進入體內的小分子有效成分群，尋找體內直接作用的藥效物質。在此基礎上研發單味中藥或複方的現代組分中藥。主持完成了包括國家基金委重大研究計畫項目，國家863項目，國家新藥創製重大專項項目，中科院知識創新重要方向項目，上海市科技發展基金項目等多項國家和省部級科研項目。
代表論著
Chunhui Ma, Zhixiong Li, Chenggang Huang* et al, Identification of major alkaloids in rat urine by HPLC-DAD-ESI-MS/MS method following oral administration of Cortex Phellodendri decoction, Helvetica Chimica Acta
Haiyan Zhu, Yuanyuan Zhang, Chenggang Huang* et al, In Vivo and in Vitro Antiviral Activities of Calycosin-7-O-β-D-glucopyranoside against Coxsackie Virus B3, Biological & Pharmaceutical Bulletin
Chunhui Ma, Yihong Tang, Chenggang Huang* et al, Identification of major alkaloids and steroidal saponins in rat serum by HPLC-DAD-MS/MS method following oral administration of Huangbai-Zhimu herb-pair Extract, Biomedical Chromatography
Chunhui Ma, Longxing Wang, Chenggang Huang* et al, Identification of major xanthones and steroidal saponins in rat urine by liquid chromatography-atmospheric pressure chemical ionization mass spectrometry technology following oral administration of Rhizoma Anemarrhenae decoction, Biomedical Chromatography
Chun-hui Ma, Ming-song Fan, Cheng-gang Huang* et al, Cytotoxic triterpenoid Saponins from Vaccaria segetalis, Journal of Asian Natural Products Research
Guan Ye, Rongrong Ma, Chenggang Huang* et al, Determination of calycosin 7-O-β-D-glucoside in rat plasma and urine by HPLC, Biomedical Chromatography
Hui Wang, Chun-hui Ma, Chenggang Huang* et al, Identification and determination of four metabolites of mangiferin in rat urine, Journal of Pharmaceutical and Biomedical Analysis
Yihong Tang, Yuanyuan Zhang, Chenggang Huang* et al, A high-performance liquid chromatographicmethod for saikosaponin a quantification in rat plasma, Biomedical Chromatography
Guan Ye, Jingjing Fang, Chenggang Huang* et al, Structure elucidation and complete NMR spectral assignments of a novel sesquiterpene glycoside from Ixeris sonchifoli. ,Magnetic Resonance in Chemistr
Kai-cheng Zhu, Chun-hui Ma, Cheng-gang Huang* et al, Two new secoiridoid Glycosides from Tripterospermum Chinense (Migo), Helvetica Chimica Acta
Guan Ye, Hua Peng, Chenggang Huang* et al, A new hopane triterpene from Dipentodon sinicus (Celastraceae), Biochemical Systematics and Ecology
Yuanyuan Zhang, Haiyan Zhu, C.G. Huang* et al, Antiviral effects of sophoridine against coxsackievirus B3 and its pharmacokinetics in rats, Life Sciences
Guan Ye, Haiyan Zhu, Chenggang Huang* et al, Determination of geniposide in rat urine after oral administration of traditional Chinese medicinal preparation Yin-Zhi-Ku decoction by high-performance liquid chromatography, Journal of chromatographic science
Yuanyuan Zhang, Haiyan Zhu, Chenggang Huang* et al, Astragaloside IV exerts antiviral effects against coxsackievirus B3 by upregulating interferon-γ, Journal of Cardiovascular Pharmacology
YH Tang, HY Zhu, CG Huang* et al, Determination of human plasma protein binding of baicalin by ulterfiltration and high performance liquid chromatography, Biomedical Chromatography
Guan Ye, Haiyan Zhu, Chenggang Huang* et al, SPE-HPLC method for the determination and pharmacokinetic studies on geniposide in rat serum after oral administration of traditional Chinese medicinal preparation Yin-Zhi-Ku decoction, Biomedical Chromatography
C.H.Ma, W.Ke, C.G. Huang* et al, Large-scale isolation and purification of scoparone from Herba artemisiae scopariae by high-speed counter-current chromatography, Chromatographia
Hui Wang, Yi-Hong Tang, Cheng-Gang Huang* et al, High-performance liquid chromatographic method for the determination of mangiferin in rat plasma and urine. Biomedical Chromatography
Chenggang Huang*，Chunhui Ma, Yihong Tang et al, Clinical Chemistry Research，Chapter 4：Identification and Analysis of Effective Components in Animal Biofluids following Administration of Natural Medicines，Nova Science Publishers Inc.NY, March, 2009
