人物經歷
1989年畢業於
南京大學化學系,獲學士學位;1992年於
武漢大學化學系獲碩士學位,留校從事教學科研工作。2002年於
武漢大學化學與分子科學學院獲理學博士學位。2000年8月-2002年2月公派赴新加坡Johns Hopkins Singapore Biomedical Center進行合作研究。2000年6月晉升為副教授,2005年6月被聘為博士生導師,2005年11月晉升為教授。
主講課程
主講
武漢大學通識教育課程“材料科學”和材料化學專業“材料化學合成基礎”。
研究方向
生物醫用高分子材料。
主要貢獻
科研項目
主持並完成
國家自然科學基金、湖北省自然科學基金和武漢市青年科技晨光計畫項目各1項;作為主要參加者完成國家重點基礎研究規劃項目(973)、國家自然科學基金重點項目、面上項目、教育部重點科技項目及高等學校博士點專項基金等項目。主持國家自然科學基金2項、教育部留學回國人員啟動基金1項,作為研究骨幹參加國家重點基礎研究規劃(973)項目、國家自然科學基金重點項目、高等學校科技創新工程重大項目培育資金各1項。
主要論文
1、 Zhang J T, Huang S W, Xue Y N, Zhuo R X. Poly(N-isopropylacrylamide) nanoparticle- incorporated PNIPAAm hydrogels with fast shrinking kinetics. Macromolecular Rapid Communication, 2005, 26,1346-1350.
2、 Zhang J T, Huang S W, Zhuo R X. A novel sol–gel strategy to prepare temperature-sensitive hydrogel for encapsulation of protein. Colloid Polymer Science, 2005,284,209-213.
3、 Zhang J T, Huang S W, Xue Y N, Zhuo R X. Novel Thermal-Sensitive beta-Cyclodextrin-Contained Poly(N-isopropylacrylamide) Hydrogels Cross-linked by Si-O-Si Bonds: Synthesis, Characterization and Prolonging in Vitro Release of 5-Fluorouracil. Chinese Journal of polymer Science, 2005, 23(5), 513-519.
4、 Zhang J T, Huang S W, Liu J, Zhuo R X. Temperature Sensitive Poly[N-isopropylacrylamide-co- (acryloyl b-cyclodextrin)] for Improved Drug Release. Macromolecular Bioscience, 2005, 5, 192-196
5、 Zhang JT, Huang SW, Gao FZ, Zhuo RX. Novel temperature-sensitive,β-cyclodextrin-incorporated poly(N-isopropylacrylamide) hydrogels for slow release of drug. Colloid Polymer Science, 2005,283,461-464
6、 Zhang XQ, Wang XL, Huang SW, Zhuo RX Liu ZL,In, Mao HQ, Leong KW. Vitro Gene Delivery Using PAMAM Dendrimers with Trimesyl Core. Biomacromolecules, 2005,6,341-350
7、 Zhang J T, Huang S W, Wang L L, Zhuo R X. Preparation and Characteristic of Fast-Responsive, Porous Poly(N-isopropylacylamide-co-Acryl Acid) Hydrogels. Submitted to Chemical Journal of Chinese University.,2004,25(12), 2370-2374
8、 Zhang J T, Huang S W , Zhuo RX. Preparation of temperature-sensitive, polyamidoamine dendrimer-incorporated poly(N-isopropylacrylamide) hydrogels with improved responsive properties. Macromolecular Bioscience, 2004, 2004, 4(6), 575-578
9、 Huang S W, Wang J, Zhang P C, Mao H Q, Zhuo R X, Leong K W. Water-soluble and Nonionic Polyphosphoester: Synthesis, Degradation, Biocompatibility and Enhancement of Gene Expression in Mouse Muscle. Biomacromolecules, 2004, 5(2), 306~311
10、Wu X Y, Huang S W, Zhang J T, Zhuo R X. Preparation and Characterization of Novel Physically Cross-linked Hydrogels Composed of Poly (vinyl alcohol) and Amine-terminated Polyamidoamine Dendrimer. Macromolecular Bioscience, 2004, 4, 71~75.
11、Zhang J T, Huang S W, Zhuo R X. Preparation and Characterization of Novel Temperature Sensitive Poly(N-isopropylacrylamide-co-acryloyl beta-cyclodextrin) Hydrogels with Fast Shrinking Kinetics. Macromolecular Chemistry and Physics, 2004, 205, 107-113.
12、Zhang J T, Huang S W, Cheng S X, Zhuo R X. Synthesis and Characteristics of Poly(N-isopropylacrylamide)/Poly(N-isopropylacrylamide) Interpenetrating Polymer Network as Drug Delivery System. Journal of Polymer Science, Part A, 2004, 42, 1249~1254.
13、Wu X Y, Huang S W, Zhang J T, Zhuo R X. Preparation and Properties of Physically cross-linked Poly (vinyl alcohol)/ Hydroxy-terminated Polyamidoamine Dendrimer Hydrogels. Chemical Journal of Chinese University, 2004, 25(2), 382~384.
14、Wang J, Huang S W, Zhang P C, Mao H Q, Leong KW. Effect of side-chain structures on gene transfer efficiency of biodegradable cationic polyphosphoesters. International Journal of Pharmaceutics, 2003, 265(1-2), 75-84.
15、Huang S W, Zhuo R X. Recent progress in polymer-based gene delivery vectors. Chinese Science Bulletin, 2003, 48(13), 1304-1309.
16、Huang S W, Fu L Z, Zhang X Q, Liu H, Li W X, Zhuo R X. Syntheses of polyamidoamine dendrimers starting from a hexadimensional core and application in gene transfer. Science in China Series B, 2003, 46(3), 271-279.
17、Zhang J T, Cheng S X, Huang S W and Zhuo R X. Temperature-sensitive poly(isopropylarylamide) hydrogel with macroporous structure and fast responsive rate. Macromolecular Rapid Communication, 2003, 24(7), 447~451.
18、Wang X L, Zhuo R X, Huang S W, Liu L J and He F. Synthesis, characterization and in vitro cytotoxicity of poly[(5-benzyloxy-trimethylene carbonate)-co-(trimethylene carbonate)]. Macromolecular Chemistry and Physics, 2002, 203(7), 985-990.
19、Huang S W, Peng W L, Shan Z X and Zhao D J. A New Facile Approach to Highly Selective Hydroboration of Alkenes with Sodium Malonyloxyborohydride. New Journal of Chemistry, 2001, 25(6), 869~871.
20、Huang S W, Guo F, Shan Z X and Zhao D J. Insertion of Dichlorocarbene into C-B Bond of Borinates under Liquid-Liquid Phase Transfer Catalysis Conditions: A convenient Preparation of unsymmetrical Ketones. Chinese Journal of Chemistry, 2001, 19(2), 202~204.
21、Guo F, Huang S W*, Shan Z X and Zhao D J, A convenient preparation of unsymmetrical ketones from borinates using phase transfer catalysis. Journal of Chemical Research, 2000, 280~281.
22、Huang S W, Wang B, Shan Z X and Zhao D J. Asymmetric reduction of acetophenone with borane catalyzed by chiral oxazaborolidinone derived from L-a-amino acids. Synthetic Communication, 2000, 30(13), 2423~2429.
獲獎記錄
獲2000年湖北省自然科學二等獎和2006年湖北省自然科學一等獎各一項。