高慧玲，女，博士，東北大學生命科學與健康學院神經科學研究所副教授、碩士研究生導師。
基本介紹
- 中文名：高慧玲
- 職業：教師
- 畢業院校：日本愛媛大學
- 學位/學歷：博士
- 專業方向：腦鋅代謝與學習記憶以及神經退行性疾病發病機理等
- 任職院校：東北大學
人物經歷,學習經歷,工作經歷,科研方向,學術成果,科研項目,發表論文,
人物經歷
學習經歷
2013年在日本愛媛大學獲得博士學位。
工作經歷
現任東北大學生命科學與健康學院神經科學研究所副教授，碩士研究生導師。
科研方向
腦鋅代謝與學習記憶以及神經退行性疾病發病機理的研究。套用轉基因小鼠模型和細胞模型，探討金屬離子及其轉運體調節腦內金屬離子代謝的分子機制。
學術成果
承擔國家自然科學基金青年基金項目1項，發表SCI收錄期刊論文11篇，其中第一作者發表SCI收錄期刊論文6篇。
科研項目
國家自然科學基金青年基金項目：D-青黴胺抑制阿爾茨海默病轉基因小鼠腦內β-澱粉樣蛋白沉積及其機制研究 (81301102)
發表論文
1.Hui-Ling Gao, Cheng Li, Nabeka Hiroaki, Shimokawa Tetsuya, Saito Shouichiro, Zhan-You Wang, Ya-ming Cao, Seiji Matsuda. Attenuation of MPTP/MPP Toxicity in vivo and in vitro by an 18-mer peptide derived from Prosaposin. Neuroscience. 236:373–393, 2013.
2. Hui-Ling Gao, Cheng Li, Hiroaki Nabeka, Tetsuya Shimokawa, Naoto Kobayashi, Shouichiro Saito, Zhan-You Wang, Ya-ming Cao, Seiji Matsuda. Decrease in prosaposin in the dystrophic mdx mouse brain. PLoS ONE. 8(11):e80032, 2013.
3. Hui-Ling Gao, He Xu, Na Xin, Wei Zheng, Zhi-Hong Chi, Zhan-You Wang. Disruption of the CaMKII/CREB signaling is associated with zinc deficiency-induced learning and memory impairments. Neurotoxicity Research. 19:584–591, 2011.
4. Hui-Ling Gao, Wei Zheng, Na Xin, Zhi-Hong Chi, Zhen-Yu Wang, Jie Chen, Zhan-You Wang. Zinc deficiency reduces neurogenesis accompanied by neuronal apoptosis through caspase-dependent and -independent signaling pathways. Neurotoxicity Research. 16 (4):416-425, 2009.
5. Hui-Ling Gao, Wan-Yu Feng, He Xu, Liping Huang, Zhan-You Wang. Golgi apparatus localization of ZNT7 in the mouse cerebellum.Histology and Histopathology. 24 (5):567-572, 2009.
6. Hui-Ling Gao, Xin Wang, Wei Zheng, Annica Dahlstrom, Liping Huang, Zhan-You Wang. Expression of zinc transporter ZnT7 in mouse superior cervical ganglion. Autonomic Neuroscience. 140 (1-2):59-65, 2008.
7. Cheng Li, Hui-Ling Gao, Tetsuya Shimokawa, Hiroaki Nabeka, Fumihiko Hamada, Hiroaki Araki, Ya-ming Cao, Naoto Kobayashi and Seiji Matsuda. Prosaposin expression in the regenerated muscles of mdx and cardiotoxin-treated mice. Histology and Histopathology. 28(7):875-892, 2013.
8. He Xu, Hui-Ling Gao, Wei Zheng, Na Xin, Zhi-Hong Chi, Shu-Ling Bai, Zhan-You Wang. Lactational zinc deficiency-induced hippocampal neuronal apoptosis by a BDNF-independent TrkB signaling pathway. Hippocampus. 21(5):495-501, 2011.
9. Bing Xue, Jie Chen, Hui-Ling Gao, Shouichiro Saito, Naoto Kobayashi, Tetsuya Shimokawa, Hiroaki Nabeka, Akira Sano, Seiji Matsuda. Chronological changes in prosaposin in the developing rat brain. Neuroscience Research. 71(1):22-34, 2011.
10. Xue-jiao Zhang, Cheng Li, Hui-Ling Gao, Hiroaki Nabeka, Tetsuya Shimokawa, Hiroyuki Wakisaka, Seiji Matsuda, Naoto Kobayashi Rho kinase inhibitors stimulate the migration of human cultured osteoblastic cells by regulating actomyosin activity. Cell and Molecular Biology Letters. 16(2):279-95, 2010.
11. Zhi-Hong Chi, Wan-Yu Feng, Hui-Ling Gao, Wei Zheng, Liping Huang and Zhan-You Wang. ZNT7 and Zn2+ are present in different cell populations in the mouse testis. Histology and Histopathology. 24: 25-30, 2009.
