高兵，男，博士，湖南大學化學化工學院教授、博士生導師。
基本介紹
- 中文名：高兵
- 畢業院校：中國科學院上海有機化學研究所
- 學位/學歷：博士
- 專業方向：化學
- 任職院校：湖南大學
人物經歷,教育經歷,工作經歷,研究領域,學術成果,獎勵榮譽,
人物經歷
教育經歷
2009 – 2014 中國科學院上海有機化學研究所，博士學位，導師：胡金波研究員
2005 – 2009 吉林大學、化學學院，學士學位
工作經歷
2019. 09 – 湖南大學、化學化工學院，教授、博導
2015 – 2019 美國斯克里普斯研究所(Scripps Research)，博士後，導師：K. Barry Sharpless 教授
2014 – 2015 中國科學院上海有機化學研究所，科研助理，導師：胡金波研究員
研究領域
氟化學、點擊化學（Click Chemistry）及其在功能材料、化學生物學領域的套用
學術成果
[1] Gao, B.; Li, S. H.; Wu, P.; Moses J. Sharpless, K. B.* “Sulfur(VI)–Carbon Link Enabled Multidimensional Sulfur(VI) Fluoride Exchange Connections from Thionyl Terafluoride (SOF4) Hub” Angew. Chem. Int. Ed. 2018, 57, 1939-1943.
[2] Gao, B.; Zhang, L. D.; Zheng, Q. H.; Zhou, F.; Klivansky, L. M.; Lu, J. M.; Liu, Y.; Dong, J. J.; Wu, P.; Sharpless, K. B.* “Bifluoride-catalysed sulfur(VI) fluoride exchange reaction for the synthesis of polysulfates and polysulfonates” Nature Chemistry 2017, 9, 1083-1088.
[3] Gao, B.; Zhao, Y.; Hu, J.*, “AgF-Mediated Fluorinative Cross-Coupling of Two Olefins: Facile Access to alpha-CF3 Alkenes and beta-CF3 Ketones.” Angew. Chem. Int. Ed. 2015, 54, 638-642.
[4] Gao, B.; Zhao, Y.; Hu, J.; Hu, J.*, “Difluoromethyl 2-pyridyl sulfone: a versatile carbonyl gem-difluoroolefination reagent.” Org. Chem. Front. 2015, 2, 163-168.
[5] Gao, B.; Hu, J.; Zhao, Y.; Hu, J.*, “Carbonyl olefination of diaryl ketones with heteroaryl sulfoxides.” Tetrahedron Lett. 2015, 56, 4180-4183.
[6] Gao, B.; Zhao, Y.; Ni, C.; Hu, J.*, “AgF-Mediated Fluorinative Homocoupling of gem-Difluoroalkenes.” Org. Lett. 2014, 16, 102-105.
[7] Gao, B.; Zhao, Y.; Hu, M.; Ni, C.; Hu, J.*, “gem-Difluoroolefination of Diaryl Ketones and Enolizable Aldehydes with Difluoromethyl 2-Pyridyl Sulfone: New Insights into the Julia-Kocienski Reaction.” Chem. Eur. J. 2014, 20, 7803-7810.
[8] Gao, B.; Ni, C.; Hu, J., “Selective Incorporation of Difluoromethylene Moieties into Arenes Assisted by Transition Metals.” Chimia 2014, 68, 414-418.
[9] Smedley, C. J.; Zheng, Q.; Gao, B.; Li, S.; Molino, A.; Duivenvoorden, H. M.; Parker, B. S.; Wilson, D. J. D.; Sharpless, K. B.; Moses, J. E., Bifluoride Ion Mediated SuFEx Trifluoromethylation of Sulfonyl Fluorides and Iminosulfur Oxydifluorides. Angew. Chem. Int. Ed. 2019, 58, 4552-4556.
[10] Miao, W.; Zhao, Y.; Ni, C.; Gao, B.; Zhang, W.; Hu, J., Iron-Catalyzed Difluoromethylation of Arylzincs with Difluoromethyl 2-Pyridyl Sulfone. J. Am. Chem. Soc. 2018, 140, 880-883.
[11] Wang, H.; Zhou, F.; Ren, G. R.; Zheng, Q. H.; Chen, H. L.; Gao, B.; Klivansky, L.; Liu, Y.; Wu, B.; Xu, Q. F.; Lu, J. M.; Sharpless, K. B.; Wu, P.* “SuFEx-Based Polysulfonate Formation from Ethenesulfonyl Fluoride-Amine Adducts” Angew. Chem. Int. Ed. 2017, 56, 11203-11208.
[12] Zhu, J.; Ni, C.; Gao, B.; Hu, J.*, “Copper(0)-mediated fluoroalkylation of iodobenzene with 2-bromo-1,1,2,2-tetrafluoroethyl compounds: Investigation on the influence of R substituent on the reactivity of RCF2Cu species.” J. Fluorine Chem. 2015, 171, 139-147.
[13] Hu, J.; Gao, B.; Li, L.; Ni, C.; Hu, J.*, “Palladium-Catalyzed Monofluoromethylation of Arylboronic Esters with Fluoromethyl Iodide.” Org. Lett. 2015, 17, 3086-3089.
[14] Zhao, Y.; Ni, C.; Jiang, F.; Gao, B.; Shen, X.; Hu, J.* “Copper-Catalyzed Debenzoylative Monofluoromethylation of Aryl Iodides Assisted by the Removable (2-Pyridyl)sulfonyl Group.” Acs. Catal. 2013, 3, 631-634.
[15] Hu, M.; He, Z.; Gao, B.; Li, L.; Ni, C.; Hu, J.* “Copper-Catalyzed gem-Difluoroolefination of Diazo Compounds with TMSCF3 via C-F Bond Cleavage.” J. Am. Chem. Soc. 2013, 135, 17302-17305.
[16] Hu, M.; Gao, B.; Ni, C.; Zhang, L.; Hu, J.* “Nucleophilic difluoro(phenylsulfonyl)methylation of carbonyls with PhSO2CF2H reagent in the presence of in situ generated substoichiometric amount of base.” J. Fluorine Chem. 2013, 155, 52-58.
[17] Zhao, Y.; Gao, B.; Ni, C.; Hu, J.* “Copper-Mediated Fluoroalkylation of Aryl Iodides Enables Facile Access to Diverse Fluorinated Compounds: The Important Role of the (2-Pyridyl)sulfonyl Group.” Org. Lett. 2012, 14, 6080-6083.
[18] Zhao, Y.; Gao, B.; Hu, J.* “From Olefination to Alkylation: In-Situ Halogenation of Julia-Kocienski Intermediates Leading to Formal Nucleophilic Iodo- and Bromodifluoromethylation of Carbonyl Compounds” J. Am. Chem. Soc. 2012, 134, 5790-5793.
[19] Huang, W.; Ni, C.; Zhao, Y.; Gao, B.; Hu, J.* “Nucleophilic difluoromethylation of N,N-acetals with TMSCF2SO2Ph reagent promoted by trifluoroacetic acid: A facile access to alpha-difluoromethylated tertiary amines.” J. Fluorine Chem. 2012, 143, 161-166.
獎勵榮譽
湖南省百人計畫（2019，青年項目）
