馬世平,男,出生於1956年3月,教授,中國藥科大學中藥學院院長、中國藥科大學中藥藥理教研室主任。
基本介紹
- 中文名:馬世平
- 國籍:中國
- 民族:漢族
- 性別:男
團體職務,主要經歷,研究領域,教學成果,發表論文,
團體職務
主要經歷
- 12-1986.06南京藥學院藥理教研室,助教
- 07-1990.03中國藥科大學中藥藥理教研室副主任,講師
- 04-1993.03 日本近畿大學藥學部學習,獲藥學碩士學位
- 10-2001.05中國藥科大學中藥學院副院長,副教授
- 06-2003.02中國藥科大學中藥學院副院長,中藥藥理教研室主任,教授
- 02-2012.06中國藥科大學圖書館館長,中藥藥理教研室主任,教授
- 06-至今中國藥科大學中藥學院院長,教授,博士生導師
研究領域
中藥及複方的藥理學研究、中藥複方的配伍機理研究
教學成果
1)抗老年性痴呆藥千金定志膠囊的研製,江蘇省科學技術委員會社會發展基金項目鑑定報告書,1999年12月,通過省科技廳組織的鑑定,第一負責人
2)抗老年性痴呆藥千金定志膠囊,2001年獲國家藥品監督管理局臨床批件,第一負責人
3)《中藥藥理學》課程獲2002年江蘇省高等學校一類優秀課程,第一負責人
4)普伐他汀鈉、普伐他汀鈉膠囊、普伐他汀鈉片,2003年獲國家藥品監督管理局臨床批件,第二負責人
發表論文
1. Protective effect of ZhenWuTang (ZWT) through keeping DA stable and VMAT2/DAT mRNA in
balance in rats with striatal lesions induced by MPTP.Journal of Ethnopharmacology,2011,
134(3):768-774
2. Ameliorative and neuroprotective effect in MPTP model of Parkinson's disease by ZhenWuTang
(ZWT),a traditional Chinese medicine.Journal of Ethnopharmacology,2010,130(1):19-27.
3. Danggui-Shaoyao-San ameliorates cognition deficits and attenuates oxidative stress-related
neuronal apoptosis in d-galactose-induced senescent mice.Journal of Ethnopharmacology,
2012, 141(1):386-395.
4. Asiaticoside: Attenuation of neurotoxicity induced by MPTP in a rat model of Parkinsonism
via maintaining redox balance and up-regulating the ratio of Bcl2/Bax.Pharmacol Biochem
Behavavior,2012,100(3):413-418.
5. Antidepressantlike effect of magnolol on BDNF upregulation and serotonergic system activity
in unpredictable chronic mild stress treated rats.Phytother Research,2012,26(8):1189-1194.
6. Paeoniflorin attenuates amyloid-beta peptide-induced neurotoxicity by ameliorating oxidative
stress and regulating the NGF-mediated signaling in rats. Brain Research,2013,1498:9-19.
7.Immunoregulatory effects of glycyrrhizic acid exerts anti-asthmatic effects via modulation of Th1/Th2 cytokines and enhancement of CD4(+)CD25(+)Foxp3+ regulatory T cells in ovalbumin-sensitized mice.[J]. Journal of Ethnopharmacology, 2013, 148(3): 755-762.
8.Curcumin attenuates allergic airway inflammation by regulation of CD4+CD25+ regulatory T cells (Tregs)/Th17 balance in ovalbumin-sensitized mice[J]. Fitoterapia, 2013, 87(1):57-64.
9.Anti-asthmatic effects of matrine in a mouse model of allergic asthma.[J]. Fitoterapia, 2014, 94(4):183-189.
10.Perillaldehyde attenuates cerebral ischemia-reperfusion injury-triggered overexpression of inflammatory cytokines via modulating Akt/JNK pathway in the rat brain cortex[J]. Biochemical & Biophysical Research Communications, 2014, 454(1):65-70.
11.Emodin opposes chronic unpredictable mild stress induced depressive-like behavior in mice by upregulating the levels of hippocampal glucocorticoid receptor and brain-derived neurotrophic factor.[J]. Fitoterapia, 2014, 98:1-10.
12.The effects of apigenin on lipopolysaccharide-induced depressive-like behavior in mice.[J]. Neuroscience Letters, 2015, 594:17.
13.Curcumin attenuates glutamate neurotoxicity in the hippocampus by suppression of ER stress-associated TXNIP/NLRP3 inflammasome activation in a manner dependent on AMPK[J]. Toxicology & Applied Pharmacology, 2015, 286(1):53-63.
14. Asiaticoside attenuates diabetes-induced cognition deficits by regulating PI3K/Akt/NF-κB pathway[J]. Behavioural Brain Research, 2015, 292:288.
15.Umbelliferone ameliorates cerebral ischemia–reperfusion injury via upregulating the PPAR gamma expression and suppressing TXNIP/NLRP3 inflammasome[J]. Neuroscience Letters, 2015, 600:182-187.
16. L-Menthone confers antidepressant-like effects in an unpredictable chronic mild stress mouse model via NLRP3 inflammasome-mediated inflammatory cytokines and central neurotransmitters[J]. Pharmacology Biochemistry & Behavior, 2015, 134:42-48.
17.The effect of isoliquiritigenin on learning and memory impairments induced by high-fat diet via inhibiting TNF-α/JNK/IRS signaling[J]. Biochemical & Biophysical Research Communications, 2015, 464(4):1090.
18.Quercetin attenuates tau hyperphosphorylation and improves cognitive disorder via suppression of ER stress in a manner dependent on AMPK pathway[J]. Journal of Functional Foods, 2016, 22:463-476.
19.Apigenin ameliorates chronic mild stress-induced depressive behavior by inhibiting interleukin-1β production and NLRP3 inflammasome activation in the rat brain.[J]. Behavioural Brain Research, 2016, 296(77):318.
20.Umbelliferone reverses depression-like behavior in chronic unpredictable mild stress-induced rats by attenuating neuronal apoptosis via regulating ROCK/Akt pathway.[J]. Behavioural Brain Research, 2017, 317:147.
21.Paeoniflorin ameliorates cognitive dysfunction via regulating SOCS2/IRS-1 pathway in diabetic rats[J]. Physiology & Behavior, 2017, 174:162-169.
22.Baicalin attenuates In Vivo and In Vitro hyperglycemia-exacerbated ischemia/ reperfusion injury by regulating mitochondrial function in a manner dependent on AMPK[J]. European Journal of Pharmacology, 2017.
23.Astragaloside IV attenuates cognitive impairments induced by transient cerebral ischemia and reperfusion in mice via anti-inflammatory mechanisms.[J]. Neuroscience Letters, 2016, 639.
24. Senegenin exerts anti-depression effect in mice induced by chronic un-predictable mild stress via inhibition of NF-KB regulating NLRP3 signal pathway. International Immunopharmacology, 2017, 53:24-32.
25. Ferulic acid attenuates diabetes-induced cognitive impairment in rats via regulation of PTP1B and insulin signaling pathway[J]. Physiology & Behavior, 2017.
26.Saikosaponin-d-mediated downregulation of neurogenesis results in cognitive dysfunction by inhibiting Akt/Foxg-1 pathwayin mice,Toxicology Letters,2017.
馬世平,男,漢族,生於1956年11月,陝西延川人,1978年11月參加工作, 1976年12月加入中國共產黨,大專學歷,現任延川縣人大主席。
1976一1978.10 在家務農 1978.11—1982.07 在賈家坪公社工作
1982.08—1987.08 在延川縣委農工部任幹事、副部長(其間:1985.9—1987.7在延安地委黨校黨政幹部大專培訓班學習,獲大專文憑)
1987.09—1988.11 任延川縣政研室副主任
1988.12—1993.11 任永坪鎮黨委書記
1993.12—1997.09 任延川縣經貿局局長兼黨委書記
1997.10—1999.05 任延川縣副縣長
1999.06—2006.09 任縣委常委、常務副縣長
2006.10—2007.09 任延川縣政協副主席(正縣級)
2007.10—2012.01 任延川縣政協主席
2012.01至今 任延川縣人大常委會主任,兼黨組書記,中共延川縣第十三屆候補委員、十四屆委員、十五、十六屆常委、十七屆委員。
1976一1978.10 在家務農 1978.11—1982.07 在賈家坪公社工作
1982.08—1987.08 在延川縣委農工部任幹事、副部長(其間:1985.9—1987.7在延安地委黨校黨政幹部大專培訓班學習,獲大專文憑)
1987.09—1988.11 任延川縣政研室副主任
1988.12—1993.11 任永坪鎮黨委書記
1993.12—1997.09 任延川縣經貿局局長兼黨委書記
1997.10—1999.05 任延川縣副縣長
1999.06—2006.09 任縣委常委、常務副縣長
2006.10—2007.09 任延川縣政協副主席(正縣級)
2007.10—2012.01 任延川縣政協主席
2012.01至今 任延川縣人大常委會主任,兼黨組書記,中共延川縣第十三屆候補委員、十四屆委員、十五、十六屆常委、十七屆委員。