陳達麗，女，1978年1月出生，中共黨員，貴州貴陽人，理學博士，研究員，中國動物學會原生動物學分會理事，中華醫學會熱帶寄生蟲病委員會青年委員，四川省動物學會理事，四川省基礎免疫專委會委員，四川省地方病與寄生蟲病專業委員會委員。
基本介紹
- 中文名：陳達麗
- 國籍：中國
- 出生日期：1978年1月
- 畢業院校：中國科學院水生生物研究所
- 學位/學歷：理學博士
- 專業方向：分子病原生物學
- 籍貫：貴州貴陽
人物經歷,發表論文,科研項目,獲獎情況,
人物經歷
2007年在中國科學院水生生物研究所獲得博士學位。2007年7月進入四川大學基礎醫學與法醫學院寄生蟲學教研室從事病原生物的物種鑑定、系統發育、種群結構、生物地理學、協同進化及感染免疫研究，2011年7月評為副教授。2013-2014年公派至美國堪薩斯大學進行學術訪問。2018年9月評為研究員。
發表論文
僅列出第一作者及通訊作者（含共同通訊作者）文章
1. He JL, Zhang JH, Liao XC, Xiao YY, Li J, Zheng ZW, Chen DL (Corresponding author) & Chen JP (Corresponding author). Upregulation of PD-1/PD-L1 and downregulation of immune signaling pathways lead to more severe visceral leishmaniasis in undernutrition mice. Parasites & Vectors, 2024, 17(1):8.
2. He JL, Huang F, Liao XC, Zhang JH, Wei SL, Xiao YY, Zheng XT, Zhu ZY, Chen DL (Corresponding author) & Chen JP (Corresponding author). TLR9 agonist CpG ODN 2395 promotes the immune response against Leishmania donovani in obesity and undernutrition mice. Acta Tropica, 2023, 242:106921.
3. Liao XC, He JL, Wang RY, Zhang JH, Wei SL, Xiao YY, Zhou Q, Zheng XT, Zhu ZY, Zheng ZW, Li J, Zeng Z, Chen DL (Corresponding author) & Chen JP (Corresponding author). TLR-2 agonist Pam3CSK4 has no therapeutic effect on visceral leishmaniasis in BALB/c mice and may enhance the pathogenesis of the disease. Immunobiology, 2023, 8(5):152725.
4. Zhou Q, Li J, Guo XG, Liu JL, Song Q, Gong X, Chen H, Zhang JH, He JL, Zheng ZW, Chen DL (Corresponding author) & Chen JL (Corresponding author). Records of three mammal tick species parasitizing an atypical host, the multi-ocellated racerunner, in arid regions of Xinjiang, China, Parasites & Vectors, 2021, 14:135.
5. Zheng ZW, Li J, Chen H, He JL, Chen QW, Zhang JH, Zhou Q, Chen DL (Corresponding author) & Chen JP (Corresponding author). Evaluation of in vitro antileishmanial efficacy of cyclosporin A and its non-immunosuppressive derivative, dihydrocyclosporin A, Parasites & Vectors, 2020, 13(1): 94.
6. Zhang JR, Guo XG, Chen H, Liu JL, Gong X, Chen DL (Corresponding author) & Chen JP (Corresponding author). Pathogenic Leishmania spp. detected in lizards from Northwest China using molecular methods. BMC Veterinary Research, 2019, 15:446.
7. He J, Huang F, Zhang J, Chen H, Chen Q, Zhang J, Li J, Zheng Z, Chen D, Chen J. DNA prime-protein boost vaccine encoding HLA-A2, HLA-A24 and HLA-DR1 restricted epitopes of CaNA2 against visceral leishmaniasis. Immunology, 2019, 156(1):94-108.
8. He J, Huang F, Li J, Chen Q, Chen D, Chen J. Bioinformatics analysis of four proteins of Leishmania donovani to guide epitopes vaccine design and drug targets selection. Acta Tropica, 2019, 191:50-59.
9. Chen H, Li J, Zhang JR, Guo XG, Liu JL , He JL, Song Q, Zhang JH, Chen ML, Zheng ZW, Chen DL (Corresponding author) & Chen JP (Corresponding author). Multi-locus characterization and phylogenetic inference of Leishmania spp. in snakes from Northwest China. PLos One, 2019, 14(4):e0210681.
10. Zeng LZ, Liao HY, Luo LZ, He SS, Qin T, Zhou HJ, Li HX, (Corresponding author) & Chen JP (Corresponding author). An Investigation on the Molecular Characteristics and Intracellular Growth Ability among Environmental and Clinical Isolates of Legionella pneumophila in Sichuan Province, China. Biomed Environ Sci. 2019, 32(7):520-530.
11. Yuan DM, Qin HX, Zhang JG, Liao L, Chen DL (Corresponding author) & Chen JP (Corresponding author). Phylogenetic analysis of HSP70 and cyt b gene sequences for Chinese Leishmania isolates and ultrastructural characteristics of Chinese Leishmania sp. Parasitology Research, 2017, 116(2):693-702.
12. Zhang JR, Guo XG, Liu JL, Zhou TH, Gong X, Chen DL (Corresponding author) & Chen JP (Corresponding author). Molecular detection, identification and phylogenetic inference of Leishmania spp. in some desert lizards from Northwest China by using internal transcribed spacer 1 (ITS1) sequences. Acta Tropica, 2016, 162:83-94.
13. He YX, Guo XG., Xiang SF, Li J, Li XQ, Xiang H, He JL, Chen DL (Corresponding author) & Chen JP (Corresponding author). Comparative analyses of phenotypic methods and 16S rRNA, khe, rpoB genes sequencing for identification of clinical isolates of Klebsiella pneumonia. Antonie Van Leeuwenhoek, 2016, 109:1029-1040.
14. Sun K, Guan W, Zhang JG, Wang YJ, Tian Y, Liao L, Yang BB, Chen DL (Corresponding author) & Chen JP (Corresponding author), 2012. Prevalence of canine leishmaniasis in Beichuan County, Sichuan, China and phylogenetic evidence for an undescribed Leishmania sp. in China based on 7SL RNA. Parasites & Vectors, 2012, 5:75.
15. Guan W, Cao DP, Sun K, Xu JN, Zhang JR, Chen DL (Corresponding author) & Chen JP (Corresponding author). Phylogenetic analysis of Chinese Leishmania isolates based on small subunit ribosomal RNA (SSU rRNA) and 7 spliced leader RNA. Acta Parasitologica, 2012, 57:101-113.
16. Cao D, Guo, X., Chen DL (Corresponding author) & Chen JP (Corresponding author). Species delimitation and phylogenetic relationships of Chinese Leishmania isolates reexamined using kinetoplast cytochrome oxidase II gene sequences. Parasitology Research, 2011, 109:163–173.
17. Yang BB, Guo XG, Hu XS, Zhang JG, Liao, L, Chen DL (Corresponding author) & Chen JP (Corresponding author). Species discrimination and phylogenetic inference of 17 Chinese Leishmania isolates based on internal transcribed spacer 1 (ITS1) sequences. Parasitology Research, 2010, 107:1049–1065.
18. Chen DL (Corresponding author), Guo XG, Nie P. Phylogenetic studies of sinipercid fish (Perciformes: Sinipercidae) based on multiple genes, with first application of an immune-related gene, the virus-induced protein (viperin) gene. Molecular Phylogenetics and Evolution, 2010, 55:1167–1176.
19. Guo XG, Chen DL (Corresponding author). Comparative evolution of the mitochondrial cytochrome b gene and nuclear S7 ribosomal protein gene intron 1 in sinipercid fishes and their relatives. Hydrobiologia, 2010, 649, 139–156.
20. Chen DL, Guo XG & Nie P. Non-monophyly of fish in the Sinipercidae (Perciformes) as inferred from cytochrome b gene. Hydrobiologia, 2007, 583:77-89.
21. Chen, DL, Wang, GT, Yao, WJ, Nie, P. Utility of ITS1-5.8S-ITS2 sequences for species discrimination and phylogenetic inference of two closely related bucephalid digeneans (Digenea: Bucephalidae): Dollfustrema vaneyi and Dollfustrema hefeiensis. Parasitology Research, 2007, 101:791-800.
科研項目
1.《西北乾旱荒漠區利什曼原蟲、白蛉和蜥蜴的協同進化研究》， 國家自然科學基金-面上項目，批准經費69.6萬元，項目編號31872959，執行時間：2019年01月-2022年12月，主持/負責人。
2.《中國利什曼原蟲種群結構與遺傳分化研究》，國家自然科學基金-面上項目，批准經費67萬，已到校經費64.25萬，項目編號31572240，執行時間：2016年01月-2019年12月，主持/負責人 。
3.《利什曼原蟲的地理起源與分化時間研究》，國家基礎科學人才培養基金-能力提高項目子課題，批准經費7萬，項目編號J1103604，執行時間：2014年9月-2015年6月，指導教師。學生結題考核答辯優秀。
4.《我國利什曼原蟲系統分類、物種形成及演化的研究》，國家自然科學基金-青年基金，批准經費20萬，項目編號30800094，執行時間：2009年1月-2011年12月，主持/負責人。
5.《杜氏利什曼原蟲複合體（Leishmania donovani complex）的分子系統發育研究》，四川大學青年科學基金，批准經費2萬，項目編號校青07056，執行時間：2008年1月-2009年12月，主持/負責人。
獲獎情況
2015和2017年，四川大學本科教學獎勵，“探究式-小班化” 教學質量優秀獎
2015年，四川大學首屆醫科微課教學比賽三等獎
2008-2011四川大學青年骨幹教師獎勵
2008年 青年教師雙語講課比賽二等獎
