陳縉泉

陳縉泉，男，博士，現任華東師範大學精密光譜科學與技術國家重點實驗室教授、博士生導師。

基本介紹

• 中文名：陳縉泉
• 學位/學歷：博士
• 職業：教師
• 專業方向：採用飛秒瞬態光譜研究生物大分子中激發態動力學過程
• 職務：華東師範大學博士生導師
• 任職院校：華東師範大學
• 職稱：教授

個人經歷

教育經歷

2007/08-2012/08，美國俄亥俄州立大學，博士

2003/09-2007/06，南京大學，學士

工作經歷

2015/10-至今，華東師範大學，精密光譜科學與技術國家重點實驗室，教授

2013/09-2015/09，美國埃默里大學，博士後研究員，合作導師：Tianquan Lian

2012/08-2013/08，美國蒙大拿州立大學，博士後研究員, 合作導師：Bern Kohler

2019年入選上海市青年科技啟明星計畫。

研究方向

主要研究方向是採用飛秒瞬態光譜研究生物大分子中激發態動力學過程

研究興趣：激發態超快動力學，生物光子學, 生物感測, 生物探針, 生物成像, DNA損傷與修復, 飛秒雷射光譜

主講課程

分子光譜學分析

社會兼職

上海市生物物理學會副理事長。

學術成果

近年來工作已在 Science, Journal of the American Chemical Society, Chemical Science, Journal of Physical Chemistry，Physical Chemistry Chemical Physics等期刊發表，目前共發表論文90餘篇。

科研項目

1.國家自然科學基金面上項目，21873030，化學修飾核酸分子電子激發態動力學特性的研究，主持

2.國家自然科學基金重大研究計畫重點，91850202，新型寬場超分辨及超高速光學顯微成像基礎研究與套用，參與

3.國家自然科學基金面上項目，11674101，基於寬頻飛秒瞬態光譜對DNA電子激發態的研究，主持

發表論文

39.Cao, X.; Zhang, C.; Gao, Z.; Liu, Y.; Zhao, Y.; Yang, Y.; Chen, J.*; Jimenez, R.*; Xu, J. Ultrafast internal conversion dynamics of bilirubin bound to unag and its n57a mutant. Phys. Chem. Chem. Phys.2019, 21, 2365-2371.

38.Zhou, Z.; Wang, X.; Chen, J.*; Xu, J. Direct observation of intramolecular charge transfer state in epigenetic nucleobase n6-methyladenine. Phys. Chem. Chem. Phys.2019, 21, 6878-6885.

37.Zhou, Z.; Hu, Z.; Zhang, X.; Jia, M.; Wang, X.; Su, H.; Sun, H.; Chen, J.*; Xu, J. Ph controlled intersystem crossing and singlet oxygen generation of 8-azaadenine in aqueous solution. ChemPhysChem 2019, 20, 757-765.

36.He, X.; Zhao, L.; Zhou, Z.; Zhang, S.; Pan, H.; Chen, J.*; Xu, J.* Near unity charge separation efficiency leads to pure ultraviolet emission in few layer graphene nanosheets. Nanotechnology 2019, 30, 295201.

35.He, X.; Zhang, S.; Pan, H.; Chen, J.*; Xu, J.* Horizontally aggregation of monolayer reduced graphene oxide under deep uv irradiation in solution. Nanoscale Research Letters 2019, 14, 117.

34.Wang, X.; Yu, Y.; Zhou, Z.; Liu, Y.; Yang, Y.; Xu, J.; Chen, J.* Ultrafast intersystem crossing in epigenetic DNA nucleoside 2′-deoxy-5-formylcytidine. J. Phys. Chem. B 2019, 123, 5782-5790.

33.Wang, F.; He, X.; Sun, L.; Chen, J.*; Wang, X.; Xu, J.; Han, X.* Engineering an n-doped tio2@n-doped c butterfly-like nanostructure with long-lived photo-generated carriers for efficient photocatalytic selective amine oxidation. Journal of Materials Chemistry A 2018, 6, 2091-2099.

32.Han, X.*; He, X.; Sun, L.; Han, X.; Zhan, W.; Xu, J.; Wang, X.; Chen, J.* Increasing effectiveness of photogenerated carriers by in situ anchoring of cu2o nanoparticles on a nitrogen-doped porous carbon yolk–shell cuboctahedral framework. ACS Catalysis 2018, 3348-3356.

31.He, H.; Xia, Y.; Qi, Y.; Wang, H.-Y.; Wang, Z.; Bao, J.; Zhang, Z.; Wu, F.-G.; Wang, H.; Chen, D., et al. A water-soluble, green-light triggered, and photo-calibrated nitric oxide donor for biological applications. Bioconjugate Chem.2018, 29, 1194-1198.

30.Pilles, B. M.; Maerz, B.; Chen, J.; Bucher, D. B.; Gilch, P.; Kohler, B.; Zinth, W.; Fingerhut, B. P.; Schreier, W. J. Decay pathways of thymine revisited. J. Phys. Chem. A 2018, 122, 4819-4828.

29.Wang, X.; Zhou, Z.; Tang, Y.; Chen, J.*; Zhong, D.; Jianhua, X. Excited state decay pathways of 2′-deoxy-5-methylcytidine and deoxycytidine revisited in solution: A comprehensive kinetic study by femtosecond transient absorption. J. Phys. Chem. B 2018, 122, 7027-7037.

28.Zhao, L.; Chen, J.*; He, X.; Yu, X.; Yan, S.; Zhang, S.; Pan, H.; Xu, J. Solvent induced fluorescence enhancement of graphene oxide studied by ultrafast spectroscopy. Chem. Phys.2018, 508, 1-6.

27.He, H.; Liu, Y.; Zhou, Z.; Guo, C.; Wang, H.-Y.; Wang, Z.; Wang, X.; Zhang, Z.; Wu, F.-G.; Wang, H., et al. A photo-triggered and photo-calibrated nitric oxide donor: Rational design, spectral characterizations, and biological applications. Free Radical Biol. Med.2018, 123, 1-7.

26.Luo, X.; Yang, H.; Wang, H.; Ye, Z.; Zhou, Z.; Gu, L.; Chen, J.; Xiao, Y.; Liang, X.; Qian, X., et al. Highly sensitive hill-type small-molecule ph probe that recognizes the reversed ph gradient of cancer cells. Anal. Chem.2018, 90, 5803-5809.

25.Jia, M.*; Zhou, Z.; Lv, M.; Chen, J.* Dual excited state deactivation pathways in tpz2: A centrosymmetric dye with both high fluorescence and triplet state quantum yield. Chin. Chem. Lett.2018, 29, 1486-1488.

24.Yang, J.; Liu, X.; Zhang, Y.; Zheng, X.; He, X.; Wang, H.; Yue, F.; Braun, S.; Chen, J.; Xu, J., et al. Comprehensive understanding of heat-induced degradation of triple-cation mixed halide perovskite for a robust solar cell. Nano Energy 2018, 54, 218-226.

23.Feng, E.; Zheng, T.; He, X.; Chen, J.; Tian, Y. A novel ternary heterostructure with dramatic sers activity for evaluation of pd-l1 expression at the single-cell level. Science Advances 2018, 4, eaau3494.

22.Gong, T.; Li, P.; Sui, Q.; Chen, J.; Xu, J.; Gao, E.-Q. A stable electron-deficient metal–organic framework for colorimetric and luminescence sensing of phenols and anilines. Journal of Materials Chemistry A 2018, 6, 9236-9244.

21.Zhou, Z.; Zhou, X.; Wang, X.; Jiang, B.*; Li, Y.*; Chen, J.*; Xu, J. Ultrafast excited-state dynamics of cytosine aza-derivative and analogues. J. Phys. Chem. A 2017, 121, 2780-2789.

20.Zhao, L.; Yu, X.; Zhang, S.; He, X.; Li, L.; Jia, M.; Chang, M.; Pan, H.; Chen, J.; Wang, W., et al. The phosphorescence and excitation-wavelength dependent fluorescence kinetics of large-scale graphene oxide nanosheets. RSC Advances 2017, 7, 22684-22691.

19.Han, X.; He, X.; Wang, F.; Chen, J.*; Xu, J.; Wang, X.; Han, X.* Engineering an n-doped cu2o@n-c interface with long-lived photo-generated carriers for efficient photoredox catalysts. Journal of Materials Chemistry A 2017, 5, 10220-10226.

18.Xing, X.; Zhao, L.; Zhang, Z.; Fang, L.; Fan, Z.; Liu, X.; Lin, X.; Xu, J.; Chen, J.; Zhao, X., et al. Photoinduced terahertz conductivity and carrier relaxation in thermal-reduced multilayer graphene oxide films. J. Phys. Chem. C 2017, 121, 2451-2458.

17.Pettinger, N. W.; Williams, R. E. A.; Chen, J.; Kohler, B. Crystallization kinetics of cerium oxide nanoparticles formed by spontaneous, room-temperature hydrolysis of cerium(iv) ammonium nitrate in light and heavy water. Phys. Chem. Chem. Phys.2017, 19, 3523-3531.

16.Chang, M.; Li, L.; Hu, H.; Hu, Q.; Wang, A.; Cao, X.; Yu, X.; Zhang, S.; Zhao, Y.; Chen, J., et al. Using fractional intensities of time-resolved fluorescence to sensitively quantify nadh/nad+ with genetically encoded fluorescent biosensors. Sci. Rep.2017, 7, 4209.

15.Lei, Z.; Yue, P.; Wang, X.; Li, X.; Li, Y.; He, H.; Luo, X.; Meng, X.; Chen, J.*; Qian, X., et al. Tpz, a bright centrosymmetric two-photon scaffold for bioimaging. Chem. Commun.2017, 53, 10938-10941.

Before join ECNU:

14.Chen, J.; Wu, K.; Rudshteyn, B.; Jia, Y.; Ding, W.; Xie, Z.-x.; Batista, V. S.; Lian, T. Ultrafast photo-induced interfacial proton coupled electron transfer from cdse quantum dots to 4, 4'-bipyridine. J. Am. Chem. Soc.2016, 138, 884-892.

13.Wu, K.; Liang, G.; Kong, D.; Chen, J.; Chen, Z.; Shan, X.; McBride, J. R.; Lian, T. Quasi-type ii cuins 2/cds core/shell quantum dots. Chem. Sci.2016, 7, 1238-1244.

12.Jia, Y.; Chen, J.; Wu, K.; Kaledin, A. L.; Musaev, D. G.; Xie, Z.; Lian, T. Enhancing photo-reduction quantum efficiency using quasi-type ii core/shell quantum dots. Chem. Sci.2016, 7, 4125-4133.

11.Li, Q.; Wu, K.; Chen, J.; Chen, Z.; McBride, J. R.; Lian, T. Size-independent exciton localization efficiency in colloidal cdse/cds core/crown nanosheet type-i heterostructures. ACS Nano 2016, 10, 3843-3851.

10.Wu, K.; Hill, L. J.; Chen, J.; McBride, J. R.; Pavlopoulos, N. G.; Richey, N. E.; Pyun, J.; Lian, T. Universal length-dependence of rod-to-seed exciton localization efficiency in type i and quasi type ii cdse@ cds nanorods. ACS nano 2015, 9,4591-4599.

9.Chen, J.; Zhang, Y.; Kohler, B. Excited states in DNA strands investigated by ultrafast laser spectroscopy. Top Curr Chem 2015, 356, 39-87.

8.Chen, J.; Kohler, B. Base stacking in adenosine dimers revealed by femtosecond transient absorption spectroscopy. J. Am. Chem. Soc.2014, 136, 6362-6372.

7.Chen, J.; Zhang, Y.; Kohler, B. Excited states in DNA strands investigated by ultrafast laser spectroscopy. Springer Berlin Heidelberg: 2014; pp 1-49.

6.Liu, R.; Dandu, N. K.; Chen, J.; Li, Y.; Li, Z.; Liu, S.; Wang, C.; Kilina, S.; Kohler, B.; Sun, W. Influence of different diimine (n^ n) ligands on the photophysics and reverse saturable absorption of heteroleptic cationic iridium (iii) complexes bearing cyclometalating 2-{3-[7-(benzothiazol-2-yl) fluoren-2-yl] phenyl} pyridine (c^ n) ligands. J. Phys. Chem. C2014, 118, 23233-23246.

5.Zhang, Y.; Chen, J.; Kohler, B. Hydrogen bond donors accelerate vibrational cooling of hot purine derivatives in heavy water. The journal of physical chemistry. A2013, 117, 6771-80.

4.Chen, J.; Thazhathveetil, A. K.; Lewis, F. D.; Kohler, B. Ultrafast excited-state dynamics in hexaethyleneglycol-linked DNA homoduplexes made of a· t base pairs. J. Am. Chem. Soc.2013, 135, 10290-10293.

3.Zhang, Y.; Dood, J.; Beckstead, A.; Chen, J.; Li, X.; Burrows, C. J.; Lu, Z.; Matsika, S.; Kohler, B. Ultrafast excited-state dynamics and vibrational cooling of 8-oxo-7, 8-dihydro-2’-deoxyguanosine in d2o. J. Phys. Chem. A2013, 117, 12851–12857.

2.Pan, Z. Z.; Chen, J. Q.; Schreier, W. J.; Kohler, B.; Lewis, F. D. Thymine dimer photoreversal in purine-containing trinucleotides. J. Phys. Chem. B2012, 116, 698-704.

1.Chen, J.; Kohler, B. Ultrafast nonradiative decay by hypoxanthine and several methylxanthines in aqueous and acetonitrile solution. Phys. Chem. Chem. Phys.2012, 14, 10677-10682.