陳章健

陳章健,男,博士,北京大學講師。。

基本介紹

  • 中文名:陳章健
  • 職業:教師
  • 學位/學歷:博士
  • 專業方向:職業衛生學,納米材料生物效應及安全性評價
  • 任職院校:北京大學
個人經歷,研究方向,學術成果,

個人經歷

2006年-2011年北京大學公共衛生學院預防醫學本科畢業。2011-2016年於北京大學公府轎抹謎衛學院勞環系獲得博士學位。2016年通過北京大學優秀博士培育計畫留校工作至今。
目前任中華預防醫學會自由基預防醫學專業委員會青年委員,Toxicology Letters、Environmental Science and Pollution Research和環境與職業醫學(中文核心)雜誌審稿人。

研究方向

職業衛生學,納米材料生物效應及安全性評價,大氣顆粒物健康效應,重金屬毒理學。

學術成果

主持和參與多項國家級課題,包括國家自然科學青年基金,973國家重點基礎研究發展計畫,十二五國家科技支撐計畫和國充悼葛家重點研發計畫等。以第一作者在領域內高質量SCI學術期刊Nanomedicine(NBM)、Toxicology Letters和Science of the Total Environment等發表論文多篇。
科研項目
1.納米二氧化鈦長期經口暴露對大鼠腸道微生物的影響研究,國家自然科學基金青年項目(81703257),20萬,2018.1.1-2020.12.30,主持。
2.食品用納米材料的ADME研究與生物安全性評價方法,國家重點研發計畫子課題(2017YFC1600204),60萬,2018.1.1-2021.12.1,項目骨幹。
3.納米二氧化鈦經口攝入對大鼠腸道菌群的影響研究,北京大學優博培育計畫(BMU20160564),15萬,2016.8.1-2019.8.1,主持,陳章健。
4.北京大學公共衛生學院青年人才計畫,8萬,2017.1.1-2019.12.30,主持,陳章健。
5.職業性接觸醫用輻射和重金屬及納米材料健康危害的控制研究,十二五國家科技支背厚束撐計畫(2014BAI12B04),101萬元,2014/10-2016/10,參加。
6.大氣顆粒物(PM2.5)及有效組分對大鼠遺傳物質損傷及修復的影響,國家自然科學基金重大研究計畫(晚閥愚培育項目,91743114),90萬元,2018/01-2020/12,參加。
7.長鏈非編碼RNA在六價鉻誘導DNA損傷修復中的功能和調控機制研究,譽協乎國家自然科學基金面上項目(81673118),50萬元,2017/01-2020/12,參煉墓懂臭加。
8.重要納米材料的生物效應機制與安全性評價研究,973國家重點基礎研究發展計畫(2011CB933402),100,2011.1.1-2015.12.30,參加去套。
代表性論文
1.Chen Z, Wang Y, Zhuo L, Chen S, Zhao L, Chen T, Li Y, Zhang W, Gao X, Li P, Wang H, Jia G. Interaction of titanium dioxide nanoparticles with glucose on young rats after oral administration. Nanomedicine-Nanotechnology Biology and Medicine, 2015, 11(7): 1633-1642.
2.Chen Z, Wang Y, Ba T, Li Y, Pu J, Chen T, Song Y, Gu Y, Qian Q, Yang J, Jia G. Genotoxic evaluation of titanium dioxide nanoparticles in vivo and in vitro. Toxicology Letters, 2014, 226(3): 314-319.
3.Chen Z, Wang Y, Zhuo L, Chen S, Zhao L, Luan X, Wang H, Jia G. Effect of titanium dioxide nanoparticles on the cardiovascular system after oral administration. Toxicology Letters, 2015, 239(2): 123-130.
4.Chen Z, Wang Y, Wang X, Zhuo L, Chen S, Tang S, Zhao L, Luan X, Jia G. Effect of titanium dioxide nanoparticles on glucose homeostasis after oral administration. Journal of Applied Toxicology, 2018, 38(6): 810-823. IF=2.909.
5.Chen Z, Cui L, Cui X, Li X, Yu K, Yue K, Dai Z, Zhou J, Jia G, Zhang J. The association between high ambient air pollution exposure and respiratory health of young children: A cross sectional study in Jinan, China. Science of the Total Environment, 2019, 656: 740-749.
6.Chen Z, Zhou D, Wang Y, Zhao L, Hu G, Liu J, Feng H, Long C, Yan T, Zhou S, Jia G. Combined effect of titanium dioxide nanoparticles and glucose on the cardiovascular system in young rats after oral administration. Journal of applied toxicology, 2019, 39(4): 590-602.
7.Chen Z, Zhou D, Zhou S, Jia G. Gender difference in hepatic toxicity of titanium dioxide nanoparticles after subchronic oral exposure in Sprague-Dawley rats. Journal of applied toxicology, 2019, 39(5):807-819.
8.Wang Y, Chen Z, Ba T, Pu J, Chen T, Song Y, Gu Y, Qian Q, Xu Y, Xiang K, Wang H, Jia G. Susceptibility of Young and Adult Rats to the Oral Toxicity of Titanium Dioxide Nanoparticles. Small, 2013, 9(9-10): 1742-1752.
9.Zhao L, Zhu Y, Chen Z, Xu H, Zhou J, Tang S, Xu Z, Kong F, Li X, Zhang Y, Li X, Zhang J, Jia G. Cardiopulmonary effects induced by occupational exposure to titanium dioxide nanoparticles. Nanotoxicology, 2018, 12(2): 169-184.
10.Xu H, Zhao L, Chen Z, Zhou J, Tang S, Kong F, Li X, Yan L, Zhang J, Jia G. Exposure assessment of workplace manufacturing titanium dioxide particles. Journal of Nanoparticle Research, 2016, 18(10).
2.Chen Z, Wang Y, Ba T, Li Y, Pu J, Chen T, Song Y, Gu Y, Qian Q, Yang J, Jia G. Genotoxic evaluation of titanium dioxide nanoparticles in vivo and in vitro. Toxicology Letters, 2014, 226(3): 314-319.
3.Chen Z, Wang Y, Zhuo L, Chen S, Zhao L, Luan X, Wang H, Jia G. Effect of titanium dioxide nanoparticles on the cardiovascular system after oral administration. Toxicology Letters, 2015, 239(2): 123-130.
4.Chen Z, Wang Y, Wang X, Zhuo L, Chen S, Tang S, Zhao L, Luan X, Jia G. Effect of titanium dioxide nanoparticles on glucose homeostasis after oral administration. Journal of Applied Toxicology, 2018, 38(6): 810-823. IF=2.909.
5.Chen Z, Cui L, Cui X, Li X, Yu K, Yue K, Dai Z, Zhou J, Jia G, Zhang J. The association between high ambient air pollution exposure and respiratory health of young children: A cross sectional study in Jinan, China. Science of the Total Environment, 2019, 656: 740-749.
6.Chen Z, Zhou D, Wang Y, Zhao L, Hu G, Liu J, Feng H, Long C, Yan T, Zhou S, Jia G. Combined effect of titanium dioxide nanoparticles and glucose on the cardiovascular system in young rats after oral administration. Journal of applied toxicology, 2019, 39(4): 590-602.
7.Chen Z, Zhou D, Zhou S, Jia G. Gender difference in hepatic toxicity of titanium dioxide nanoparticles after subchronic oral exposure in Sprague-Dawley rats. Journal of applied toxicology, 2019, 39(5):807-819.
8.Wang Y, Chen Z, Ba T, Pu J, Chen T, Song Y, Gu Y, Qian Q, Xu Y, Xiang K, Wang H, Jia G. Susceptibility of Young and Adult Rats to the Oral Toxicity of Titanium Dioxide Nanoparticles. Small, 2013, 9(9-10): 1742-1752.
9.Zhao L, Zhu Y, Chen Z, Xu H, Zhou J, Tang S, Xu Z, Kong F, Li X, Zhang Y, Li X, Zhang J, Jia G. Cardiopulmonary effects induced by occupational exposure to titanium dioxide nanoparticles. Nanotoxicology, 2018, 12(2): 169-184.
10.Xu H, Zhao L, Chen Z, Zhou J, Tang S, Kong F, Li X, Yan L, Zhang J, Jia G. Exposure assessment of workplace manufacturing titanium dioxide particles. Journal of Nanoparticle Research, 2016, 18(10).

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