中山大學海洋學院特聘副研究員,中山大學博士。
基本介紹
- 畢業院校:2017年中山大學博士
教育經歷
2008年9月-2012年6月華南農業大學,套用化學專業,理學學士。
2012年9月-2017年6月中山大學,有機化學專業,理學博士(碩博連讀)。
工作經歷
2017.8-至今中山大學海洋科學學院特聘副研究員
研究方向
天然產物化學、化學生物學
發明專利
1. 佘志剛陳森華劉昭明劉亞月譚春兵陸勇軍何磊,一類海洋真菌來源的縮酚酸類化合物及其治療II型糖尿病的套用,申請號:201510205871.1,申請日期:2015-04-27,申請授權號:CN104987319A,授權公布日:2017-05-17。
2. 佘志剛陳森華陸勇軍陳冬妮黃錫山,海洋真菌來源的萘螺縮酮類化合物及其製備方法和套用,申請號:201610488071.X,申請日期:2016-06-24,申請公開號:106188084A,申請公布日:2016-12-07。
代表性論文
1. Senhua Chen, Meng Ding, Weiyang Liu, Xishan Huang,Zhaoming Liu,Yongjun Lu, Hongju Liu, Zhigang She. Antiinflammatory meroterpenoids from the mangrove endophytic fungus Talaromyces amestolkiaeYX1. Phytochemistry. 2018,146, 8-15.
2. Senhua Chen, Zhaoming Liu, Hongju Liu, Yuhua Long, Dongni Chen, Yongjun Lu, Zhigang She*. Lasiodiplactone A, a novel lactone from the mangrove endophytic fungus Lasiodiplodia theobromae ZJ-HQ1. Org Biomol Chem, 2017, 15, 6338-6341.
3. Senhua Chen, Liqing He, Dongni Chen, Ruilin Cai, Yuhua Long, Yongjun Lu, and Zhigang She*, Talaramide A, an unusual alkaloid from the mangrove endophytic fungus Talaromyces sp. (HZ-YX1) as Inhibitor of mycobacterial PknG, New J Chem, 2017, 41, 4273-4276.
4. Panpan Zhang, Yongfang Li, Chunxiu Jia, Jiajia Lang, ShahIram Niaz, Jing Li, Jie Yuan, Jianchen Yu,Senhua Chen* , Lan Liu* Antiviral and anti-inflammatory meroterpenoids: stachybonoids A–F from the crinoid-derived fungus Stachybotrys chartarum 952, RSC Adv., 2017, 7, 49910-49916.
5. Panpan Zhang, Jing Li, Jiajia Lang, Chunxiu Jia, Shah-Iram Niaz, Senhua Chen* and Lan Liu. Two new sesquiterpenes derivatives from marine fungus Leptosphaerulina Chartarum sp. 3608.Nat Prod Res, 2017: 1-7.
6. Senhua Chen, Dongni Chen, Runlin Cai, Hui Cui, Yuhua Long, Yongjun Lu, Chunyuan Li, and Zhigang She*,Cytotoxic and Antibacterial Preussomerins from the Mangrove Endophytic Fungus Lasiodiplodia theobromae ZJ-HQ1,J Nat Prod, 2016, 79(9): 2397-2402.
7. Senhua Chen, Yayue Liu, Zhaoming Liu, Runlin Cai, Yongjun Lu, Xishan Huang, Zhigang She*Isocoumarins and benzofurans from the mangrove endophytic fungus Talaromyces amestolkiae possess α-glucosidase inhibitory and antibacterial activities, RSC Adv, 2016, 6(31): 26412-26420.
8. Senhua Chen, Zhaoming Liu, Yayue Liu, Yongjun Lu, Lei He, Zhigang She*, New depsidones and isoindolinones from the mangrove endophytic fungus Meyerozyma guilliermondii (HZ-Y2) isolated from the South China Sea,Beilstein J Org Chem, 2015, 11(1): 1187-1193.
9. Senhua Chen,Zhaoming Liu, Hanxiang Li,Guoping Xia,Yongjun Lu, Lei He, Shaodong Huang, Zhigang She*, bResorcylic acid derivatives withαglucosidase inhibitory activity from Lasiodiplodia sp. ZJHQ1, an endophytic fungus in the medicinal plant Acanthus ilicifolius, Phytochem Lett, 2015, 13: 141-146.
10. Ze’en Xiao, Senhua Chen, Runlin Cai, Shao’e Lin, Kui Hong, Zhigang She*, New furoisocoumarins and isocoumarins from the mangrove endophytic fungus Aspergillus sp. 085242,Beilstein J Org Chem, 2016, 12(1): 2077-2085.
11. Runlin Cai, Senhua Chen, Yuhua Long, Chunyuan Li, Xishan Huang, Zhigang She,Depsidones from Talaromyces stipitatus SK4, an endophytic fungus of the mangrove plant Acanthus ilicifolius. Phytochem Lett, 2017, 20: 196-199. DOI:10.1016/j.phytol.2017.04.023.
12. Zhaoming Liu, Senhua Chen, Pei Qiu, Chunbing Tan, Yuhua Long, Yongjun Lu and Zhigang She.Ascomlactone A, a pair of Novel Dimeric Polyketides from a Mangrove Endophytic Fungus Ascomycota sp. SK2YWS-L." Org Biomol Chem, 2017.
13. Yayue Liu, Senhua Chen, Zhaoming Liu, Yongjun Lu, Guoping Xia, Hongju Liu, Lei He, Zhigang She*, Bioactive Metabolites from Mangrove Endophytic Fungus Aspergillus sp. 16-5B, Marine Drugs, 2015, 13(5): 3091-3102.
14. Hongju Liu, Senhua Chen , Weiyang Liu, Yayue Liu, Xishan Huang, Zhigang She*,Polyketides with Immunosuppressive Activities from Mangrove Endophytic Fungus Penicillium sp. ZJ-SY2, Marine Drugs,2016, 14(12): 217.
15. Runlin Cai, Senhua Chen, Zhaoming Liu, Chunbing Tan, Xishan Huang, Zhigang She. A new α-pyrone from the mangrove endophytic fungus Phomopsis sp. HNY29-2B. Nat Prod Res, 2016, 31(2):1-7.
16 Zhaoming Liu, Yan Chen, Senhua Chen, Yayue Liu, Yongjun Lu, Dongni Chen, Yongcheng Lin, Xishan Huang, Zhigang She*, Aspterpenacids A and B, Two Sesterterpenoids from a Mangrove Endophytic Fungus Aspergillus terreus H010, Org Lett, 2016, 18(6): 1406-1409.
17 Chunbin Tan, Zhaoming Liu, Senhua Chen, Xishan Huang,Hui Cui,Yuhua Long,Yongjun Lu,Zhigang She*,Antioxidative Polyketones from the MangroveDerived Fungus Ascomycota sp. SK2YWS-L,Sci Rep, 2016, 6.
18 Zhaoming Liu, Guoping Xia, Senhua Chen, Yayue Liu, Hanxiang Li, Zhigang She*,Eurothiocin A and B, SulfurContaining Benzofurans from a Soft Coral Derived Fungus Eurotium rubrum SH-823,Marine Drugs,2014, 12(6): 3669-3680.
19 Hui Cui, Jianchen Yu, Senhua Chen, Meng Ding, Xishan Huang, Jie Yuan, Zhigang She.Alkaloids from the mangrove endophytic fungus Diaporthe phaseolorm SKS019. Bioorg Med Chem Lett, 2017, 27(4): 803-807.
20 Hui Cui , Yayue Liu , Yang Nie, Zhaoming Liu, Senhua Chen, Zhengrui Zhang, Yongjun Lu, Lei He, Xishan Huang, Zhigang She . Polyketides from the mangrovederived endophytic fungus Nectria sp. HN001 and their α-glucosidase inhibitory activity. Marine drugs, 2016, 14(5): 86