基本介紹
- 中文名：陳懷俠
- 學位/學歷：博士
- 職業：教師
- 專業方向：分析化學
- 任職院校：湖北大學
研究方向,主講課程,社會兼職,榮譽獎項,學術成果,
研究方向
長期從事複雜樣品分離分析研究工作，主要內容包括：（1）現代分離技術：樣品前處理方法、色譜-質譜分析；
（2）環境分析：環境（微）微污染物分析；
（3）食品分析：食品農殘等毒物分析和食品安全；
（4）藥物分析：藥物（代謝）分析、藥物體內過程研究、中藥活性成分分離分析。
（5）新型（微）萃取介質合成及其套用：分子印跡聚合物、整體柱、納米磁微粒、新型碳材料、金屬有機骨架和金屬簇材料等；
（6）生物、食品和環境等實際樣品微量及痕量組分分析：藥物分析、藥物體內過程、食品農殘、環境（微）污染物和日化品毒素殘留等
主講課程
主講分析化學及實驗、儀器分析及實驗和現代分離科學（本科生和研究生）等課程，教學質量評價優秀。
社會兼職
湖北省色譜質譜學術委員會委員；湖北省“教學名師”工作室主持人；湖北省分析化學資源共享課程負責人；湖北大學分析化學系列課程教學團隊負責人；教育部入庫專家；中國化學會會員。
榮譽獎項
湖北省教學成果一等獎（排名第四）；中共湖北省委優秀黨務工作者；湖北大學教學成果一等獎（排名第六）；湖北大學教學名師；湖北大學優秀教師；湖北大學2009年度和2001年度本科教學質量優秀獎；湖北大學優秀黨員；湖北大學工會優秀女會員；湖北大學優秀教案三等獎。
學術成果
代表性研究成果（30篇代表作）：
(1)Yinpeng Yang, Yuan Sun, Hang Chen, Xueping Dang, Youhong Ai, Xiaolan Liu,Huaixia Chen*, Mesoporous yolk-shell structure molecularly imprinted magnetic polymers for the extraction and detecetion of 17β-estradiol.AnalyticalMethods, 2020,12, 507-513.
(2)Qiong Ma，Yingying Zhang，Xueping Dang，Jianlin Huang，Youhong Ai，Huaixia Chen*, Adsorption Behavior of Polycyclic Aromatic Hydrocarbons on Zn-Based Coordination Cluster Zn5: Competition, Synergy and Mechanism.Langmuir2019, 35, 49, 16071-16078.
(3)Ling Chen, Ming Li, Youhong Ai, Xueping Dang, Jianlin Huang,Huaixia Chen*.One-pot preparationofan acryloyledβ-cyclodextrin-silica hybrid monolithic column and its application for determination of carbendazim and carbaryl.Food Chemistry, 2018, 269(15): 181-186.
(4)Ling Chen, Xueping Dang, Youhong Ai,Huaixia Chen*.Preparation ofacryloylβ-cyclodextrin-silica hybrid monolithic column and its application in pipette tip solid phase extraction and HPLC analysis of methyl parathion and fenthion.Journal of Separation Science,2018, 41(18): 3508-3514.
(5)JianliZhu,DongpingChen, YouhongAi,Xueping Dang, Jianlin Huang,Huaixia Chen*. A dummy molecularly imprinted monolith for selective solid-phase microextraction of vanillin and methyl vanillin prior to their determination by HPLC.Microchimic Acta2017, 184(4):1161-1167.
(6)X Ma, F Feng, Y Yang, X Dang, J Huang,H Chen*.Magnetic Solid-Phase Extraction of N,N-Diethyl-m-Toluamide From Baby Toilet Water Prior to its HPLC-UV Detection.Journal of Chromatographic Science2017,55 (6): 662-668.
(7)Di Chen, Xiaoxuan Han, Qi Wang, Liujing Xie, Youhong Ai, Xueping Dang, Jianlin Huang,Huaixia Chen*. Magnetic molecular imprinted polymers for selective extraction and determination of naphthols.Microchimic Acta2017, 184: 3373-3379.
(8)Bin Sun, Chunpeng Wang, Qi Wang, Ling Chen, Xueping Dang, Jianlin Huang,Huaixia Chen*. Preparation of acryloyl β-cyclodextrin organic polymer monolithic column and its application in solid phase microextraction and HPLC analysis for carbofuran and carbaryl in rice.Food Analytical Methods2017, 10: 3847-3855.
(9)Yang Yang, Xiaowei Ma, Fan Feng, Xueping Dang, Jianlin Huang,Huaixia Chen*. Magnetic solid-phase extraction of triclosan using core-shell Fe3O4@MIL-100 magnetic nanoparticles, and its determination by HPLC with UV detection.Microchimic Acta2016, 183(8): 2467-2472.
(10)Bo Wu, Jinxia Li,Huaixia Chen*, Yong Ye. Fate of metronidazole under solar irradiation.Environmental Engineering and Management Journal2016, 15(1): 1003-1008.
(11)Ning Li,Quanfei Zhu,Yang Yang,Jianlin Huang,Xueping Dang,Huaixia Chen*. A novel dispersive solid-phase extraction method using metal-organic framework MIL-101 as the adsorbent for the analysis of benzophenones in toner.Talanta2015,132(15): 713-718.
(12)Xiaofang Liu, Shu Zhou, Quanfei Zhu, Yong Ye,Huaixia Chen*.Ultra preconcentration of polycyclic aromatic hydrocarbons in smoked bacon by a combination of SPE and DLLME.Journal of Chromatographic Science2014, 52(8): 932-937.
(13)Quanfei Zhu, Chao Ma,Huaixia Chen*, Yaqi Wu, Jianlin Huang. A molecular imprint-coated stirrer bar for selective extraction of caffeine, theobromine and theophylline.Microchimic Acta2014, 181(3-4): 303-311.
(14)Ting Yang, Chao Ma,Huaixia Chen*, Yajie Zhang, Xueping Dang, Jianlin Huang. A molecularly imprinted organic-inorganic hybrid monolithic column for selective extraction and high-performance liquid chromatography determination of isoprocarb residues in rice.Journal of Separation Science2014,37: 587-594.
(15)Xiaofang Liu, Quanfei Zhu,Huaixia Chen, Liuzi Zhou, Xueping Dang, Jianlin Huang. Preparation of 2,4-dichlorophenoxyacetic acid imprinted organic–inorganic hybrid monolithic column and application to selective solid-phase microextraction.Journal of Chromatography B2014, (951-952): 32-37.
(16)Ting Zhang, Chao Ma, Mei Wu, Yong Ye,Huaixia Chen*,Jianlin Huang. Selective microextraction of carbaryl and naproxen using organic-inorganic monolithic columns containing a double molecular imprint.Microchimic Acta2013, 180: 695-702.
(17)Ting Zhang, Bo Wu, Na Sun, Yong Ye,Huaixia Chen*.Sorption and degradation of wastewater-associatedpharmaceuticalsand personal care products inagricultural soils and sediment.Water Science and Technology2013, 68 (5): 991-998.
(18)Xiaofang Liu, Na Sun, Quanfei Zhu, Mei Wu, Yong Ye,Huaixia Chen*. Preparation, characterization and application of organic-inorganic hybrid caffeine imprinted monolith.Journal of Chromatography A2013, 1304: 10-17.
(19)Juan Li,Huaixia Chen*, Hui Chen and Yong Ye.Selective determination of trace thiamphenicol in milk and honey by molecularly imprinted polymer monolith microextraction and high-performance liquid chromatography.Journal of Separation Science2012, 35 (1): 137-144.
(20)Shu Zhou,Huaixia Chen*, Bo Wu, Chao Ma, Yong Ye. Sensitive determination of carbamates in fruit and vegetables by a combination of solid-phase extraction and dispersive liquid-liquid microextraction prior to HPLC.Microchimic Acta2012, 176: 419-427.
(21)Shu Zhou, Bo Wu, Chao Ma, Yong Ye.Huaixia Chen*. Solid-phase extraction followed by dispersive liquid-liquid microextraction for the sensitive determination of carbamates in environmental water by high-performance liquid chromatography.Journal of Liquid Chromatography and Related Technologies2012, 35: 1-13.
(22)Bo Wu, Ting Zhang, Jinxia Li, Yong Ye.Huaixia Chen*.The photodegradation of metronidazole in the presence of coexisting pharmaceuticals.Water Science and Technology2012, 735-740.
(23)Na Sun, Shengli Wu,Huaixia Chen*, Daijun Zheng, Junwen Xu, Yong Ye. Determination of sulfamethoxazole in milk using molecularly imprinted polymer monolith microextraction coupled to HPLC.MicrochimicActa2012, 179: 33-40.
(24)Chao Ma, Hui Chen, Na Sun, Yong Ye,Huaixia Chen*. Preparation of Molecularly Imprinted Polymer Monolith with an Analogue of Thiamphenicol and Application to Selective Solid-Phase Microextraction.Food AnalyticalMethods2012, 5: 1267-1275.
(25)Jinfang Zhou, Chao Ma, Shu Zhou, Peili Ma, Fangrong Chen, Yue Qi,Huaixia Chen*.Preparation, evaluation and application of molecularly imprinted solid-phase microextraction monolith for selective extraction of pirimicarb in tomato and pear.Journal of Chromatography A2010, 1217: 7478-7483.
(26)Huaixia Chen*, Jianlin Huang, Juan Li.Characterization of metabolites of worenine in rat biological samples using liquid chromatography–tandem mass spectrometry.Journal of Pharmaceutical and Biomedical Analysis2010, 51: 236-243.
(27)Huaixia Chen*, Hui Chen, Lei Liao, Jun Ying, and Jianlin Huang. Determination of thiamphenicol in honey by dispersive liquid-liquid microextractionwith high-performance liquid chromatography.Journal of Chromatographic Science2010, 48: 450-455.
(28)Huaixia Chen*, Hui Chen, Jun Ying, Jianlin Huang, Lei Liao. Dispersive liquid-liquid microextraction followed by high-performance liquid chromatography as an efficient and sensitive technique for simultaneous determination of chloramphenicol and thiamphenicol in honey.Analytica Chimica Acta2009, 632：80-85.
(29)Mingming Zhu, Fengmei Han,Huaixia Chen, Zhihong Peng, Yong Chen. Identification of palmatine and its metabolites in rat urine by liquid chromatography-tandem mass spectrometry.RapidCommunications in Mass Spectrometry2007, 21(13): 2019-2022.
(30)陳懷俠，孫斌，陳玲.一種β-環糊精雜化聚合物整體微柱的製備方法及其套用，國家發明專利ZL201611049210.5.
編寫出版教材：
（1）《分析化學》主編，科學出版社，2019年；
（2）《儀器分析實驗》主編，科學出版社，2017年；
（3）《無機及分析化學》副主編，科學出版社，2009年；
（4）《無機及分析化學》主審，中國林業出版社，2012年。
主持教研項目：
（1）教育部產學合作育人項目，基於產學合作育人的分析化學教學內容和課程體系改革，2018.1-2019.12；
（2）湖北省高等學校省級教學研究項目，分析化學課程群新體系構建與實踐，2015.1-2016.12；
（3）湖北省高等學校省級教學研究項目，設計性（研究性）實踐教學內容的研究與實踐，2006.1-2008-12；
（4）湖北大學教研項目，分析化學慕課，2018.9-2019.8；
（5）湖北大學教研項目，製藥工程專業人才培養平台全方位搭建與實踐，2017.5-2019.8；
（6）湖北大學教研項目，現代分析化學課程群，2016.12-2018.12；
（7）湖北大學教研項目，現代分離科學教材建設，2016.12-2018.12；
（8）湖北大學教學專項建設項目，製藥工程專業建設，2016.6-2020.12；
（9）湖北大學教學研究項目，分析化學精品課程群建設，2011.1-2013.7。
教研論文：在“大學化學”和“化工高等教育”等刊物發表教研論文26篇。
承擔項目與課題（10項代表）：
（1）國家自然科學基金，新型微污染物PPCPs及其代謝轉化物分布調查和遷移轉化規律研究（20975030），主持人；
（2）國家自然科學基金重點項目，確有療效複方中藥痹祺膠囊的藥代動力學研究（30630075），主要成員；
（3）國家自然科學基金重點項目，新螢光探針標記磷酸化蛋白的毛細管電泳測定和細胞成像研究（20575047），主要成員；
（4）教育部科學技術研究重點項目，湖北地道藥材黃連活性成分代謝及其與血漿蛋白結合研究（208090），主持人；
（5）湖北省自然科學基金，新型微污染物PPCPs及其代謝轉化物分析研究（2009CDB364），主持人；
（6）湖北省科技廳科技攻關項目，莨菪烷類生物鹼藥代動力學藥代產物研究（2004AA301C106），主持人；
（7）湖北省教育廳重點項目，湖北省水環境中防曬劑污染分析及自然光降解研究（D20120106），主持人；
（8）省部共建教育部重點實驗室項目，中藥黃酮類化合物指紋圖譜及含量測定研究（2005-KL-009），主持人；
（9）省部共建教育部重點實驗室項目，金屬簇合物共聚整體材料合成及其吸附分離套用（02004417502），主持人；
（10）省部共建教育部重點實驗室項目，環糊精超分子聚合物整體功能材料製備及其微萃取套用研究（2016-KL-009），主持人。
