陳尚武,男,博士,中山大學生命科學學院教授、博士生導師。
基本介紹
- 中文名:陳尚武
- 學位/學歷:博士
- 專業方向:生物化學與分子生物學
- 任職院校:中山大學
講授課程
學術成果
在研項目
- 天然免疫與適應性免疫應答的協作與交替演化,“973”項目子課題,2015.01-2017.8
- 先天免疫抗病毒新機制的發現與比較研究,廣州市科技計畫重點項目,2016.01-2018.12
- (宮頸)癌前病變的Warburg-like effect與糖代謝重編程機制研究,國家自然科學基金面上項目,2017.01-2020.12
論文專著
- Yu L*, Chen X, Sun X, Wang L, Chen S*. The Glycolytic Switch in Tumors: How Many Players Are Involved? J Cancer. 2017 Sep 20;8(17):3430-3440.
- Sun X, Liu X, Xia M, Yang S, Fei L, Zhang M, Ma H, Wang L, Chen S*, Yu L*.The combined application of urinary liquid-based cytology with fluorescence in situ hybridization and p16/Ki-67 dual immunostaining is valuable for improving the early diagnosis of upper tract urothelial carcinomas. Diagn Cytopathol. 2017 Oct;45(10):895-902.
- Yu L*, Chen X, Wang L, Chen S*. The sweet trap in tumors: aerobic glycolysis and potential targets for therapy. Oncotarget. 2016 Jun;7(25):38908-38926.
- Ma H, Tian T, Liang S, Liu X, Shen H, Xia M, Liu X, Zhang W, Wang L, Chen S*, Yu L*. Estrogen receptor-mediated miR-486-5p regulation of OLFM4 expression in ovarian cancer. Oncotarget. 2016 Mar;7(9):10594-605.
- Duan C, Liu X, Liang S, Yang Z, Xia M, Wang L, Chen S*, Yu L*.Oestrogen receptor-mediated expression of Olfactomedin 4 regulates the progression of endometrial adenocarcinoma. J Cell Mol Med. 2014 May;18(5):863-74.
- Liang S, Tian T, Liu X , Shi H, Tang C, Yang S, Wang L, Chen S , Yu L*. Microarray analysis revealed markedly differential miRNA expression profiles in cervical intraepithelial neoplasias and invasive squamous cell carcinoma. Future Oncol. 2014 Oct;10(13):2023-32.
- Yu L*, Duan C, He M, Yang Z, Chen G, Shi H, Yang S, Wang L, Chen S*. Diagnostic Value of HMGB1Immunostaining on Cell Blocks From Residual Liquid-Based Gynecologic Cytology Specimens. Diagn Cytopathol. 2014 Sep;42(9):802-8.
- Yu L*, Wang L, Chen S*. Dual character of Toll-like receptor signaling: Pro-tumorigenic effects and anti-tumor functions. Biochim Biophys Acta. 2013 Apr;1835(2):144-154.
- Yu L*, Wang L, Chen S. Exogenous or endogenous Toll-like receptor ligands: which is the MVP in tumorigenesis? Cell Mol Life Sci. 2012 Mar;69(6):935-49
- Yu L*, He M, Yang Z, Chen G, Li M, Wang L, Chen S*. Olfactomedin 4 Is a Marker for Progression of Cervical Neoplasia. Int J Gynecol Cancer. 2011 Feb;21(2):367-372.
- Yu L, Wang L, Chen S. Olfactomedin 4, a novel marker for the differentiation and progression of gastrointestinal cancers. Neoplasma. 2011 Jan;58(1):9-11.
- Yu L*, Wang L, Chen S*. Endogenous Toll-like receptor ligands and their biological significance. J Cell Mol Med. 2010 Nov;14(11):2592-603.
- Yu L*, Wang L, Li M, Zhong J, Wang Z, Chen S*. Expression of toll-like receptor 4 is down-regulated during progression of cervical neoplasia. Cancer Immunol Immunother. 2010 Jul;59(7):1021-8.
- Yu L*, Wang L, Zhong J, Chen S*. Diagnostic value of p16INK4A, Ki-67, and human papillomavirus l1 capsid protein immunochemical staining on cell blocks from residual liquid-based gynecologic cytology specimens. Cancer Cytopathol. 2010 Feb;118(1):47-55.
- Yu L*, Wang L, Chen S*. Toll-like receptors, inflammation and tumor in the human female reproductive tract. Am J Reprod Immunol. 2009 Jul;62(1):1-8.
- Yu L,Chen S*. Toll-like receptors expressed in tumor cells: targets for therapy. Cancer Immunol Immunother. 2008 Sep;57(9):1271-8.