陳國勝，性別：男，出生年月：1990-05，籍貫：廣東，現為中山大學化學學院副教授、博士生導師。
基本介紹
- 中文名：陳國勝
- 學位/學歷：博士
- 職業：教師
人物經歷,教育經歷,工作經歷,科研方向,科研項目,獎勵情況,代表性論文,
人物經歷
教育經歷
2013.09-2018.06：中山大學物理化學專業，博士（導師：歐陽鋼鋒教授）
2009.09-2013.06：中山大學套用化學專業，學士
工作經歷
2021.02- 中山大學化學學院，副教授
2018.12-2020.12：中山大學化學學院，博士後
科研方向
新型功能材料的設計及面向生命健康套用，包括蛋白質-多孔有機框架複合材料、酶固定化新技術、生物感測及標誌物分析新方法等方面的研究工作。
科研項目
主持的部分科研項目：
1. 國家自然科學基金面上項目（2022-01至2025-12，61萬，項目負責人）
2. 國家自然科學基金青年項目（2020-01至2022-12，26萬元，項目負責人）
3. 廣東省自然科學基金傑出青年基金項目（已獲批，100萬元，項目負責人）
4. 中國博士後創新人才計畫（2019-09至2021-08，60萬，項目負責人）
5. 中國博士後基金面上項目（2019-05至2021-05，8萬，項目負責人）
6. 廣東省自然科學基金面上項目（2019-10至2022-09，10萬元，項目負責人）
7. 中山大學青年拔尖人才計畫（2023-01至2024-12，40萬，項目負責人）
8. 中山大學青年教師培育項目（2019-01至2021-12，15萬，項目負責人）
獎勵情況
1. 2022年中國分析測試協會科學技術獎CAIA獎特等獎（第二完成人）
2. “微瑞杯”第二屆全國大學生化學實驗創新設計競賽總決賽特等獎（指導老師）
3. 入選由英國分析化學家網評選的2022年度全球40位40歲以下精英分析化學家名單
4. 入選2023年度全球前2%頂尖科學家榜單
代表性論文
(1) Huang, Siming; Chen,Guosheng*; Ouyang, Gangfeng*. Confining enzymes in porous organicframeworks: from synthetic strategy and characterization to healthcareapplications. Chem.Soc. Rev. 2022, 51, 6824-6863 (ESI highly cited paper).
(2) Chen,Guosheng*; Huang, Siming; Ma, Xiaomin; He, Rongwei; Ouyang, Gangfeng*.Encapsulating and stabilizing enzymes using hydrogen-bonded organic frameworks.Nat. Protoc. 2023, 18, 2032–2050.
(3) Tong, Linjing;Huang, Siming; Shen, Yujian; Liu, Suya; Ma, Xiaomin; Zhu, Fang; Chen, Guosheng*; Ouyang,Gangfeng. Atomically unveiling the structure-activity relationship ofbiomacromolecule-metal-organic frameworks symbiotic crystal. Nat. Commun. 2022, 13, 951 (ESI highly cited paper)
(4) Chen, Guosheng*; Tong, Linjing;Huang, Siming; Huang, Shuyao; Zhu, Fang; Ouyang, Gangfeng*. Hydrogen-bondedorganic framework biomimetic entrapment allowing non-native biocatalyticactivity in enzyme. Nat. Commun. 2022, 13, 4816 (Featured Articlein chemical biology).
(5) Huang, Wei;Yuan, Haitao; Yang, Huangsheng; Ma, Xiaomin; Huang, Shuyao; Zhang, Hongjie;Huang, Siming; Chen, Guosheng*;and Ouyang, Gangfeng*.Green synthesis of stable hybrid biocatalyst using ahydrogen-bonded, π-π-stacking supramolecular assembly for electrochemicalimmunosensor. Nat.Commun. 2023, 14, 3644 (Featured Article in chemical biology).
(6) Huang, Siming*; Li, Jiansheng; Lin, Yuhong; Tong,Linjing; Zhong, Ningyi; Huang, Anlian; Ma, Xiaomin; Huang, Shuyao; Yi, Wei;Shen, Yong*; Chen, Guosheng*;Ouyang, Gangfeng*. Hydrogen-bonded supramolecular nanotrap enabling thein-terfacial activation of hosted enzyme. J. Am. Chem. Soc. 2024, 146, 3, 1967–1976
(7) Chen,Guosheng#; Huang, Siming#; Shen, Yong; Kou, Xiaoxue; Ma, Xiaomin;Huang, Shuyao; Tong, Qing; Ma, Kaili; Chen, Wen; Wang, Peiyi; Shen, Jun; Zhu,Fang; Ouyang, Gangfeng*. Proteins-directed, hydrogen-bonded biohybridframework. Chem 2021, 7, 2722-2742.
(8) Tong, Linjing; Lin, Yuhong; Kou, Xiaoxue; Shen, Yujian;Shen, Yong*; Huang, Siming*; Zhu, Fang; Chen,Guosheng*; Ouyang, Gangfeng. Pore-Environment-Dependent PhotoresponsiveOxidase-like Activity in Hydrogen-Bonded Organic Frameworks. Angew. Chem.Int. Ed. 2023, 62, e202218661(VIP paper).
(9) Tang, Zhuopeng#;Li, Xinyi#; Tong, Linjing; Yang, Huangsheng; Wu,Jiayi; Zhang, Xiliu; Song,Ting*; Huang, Siming*; Zhu, Fang; Chen,Guosheng*; Ouyang, Gangfeng. A Biocatalytic Cascade in an UltrastableMesoporous Hydrogen Bonded Organic Framework for Point-of-Care Biosensing. Angew. Chem.Int. Ed. 2021, 60, 23608-23613(Hot paper).
(10) Chen,Guosheng#; Huang, Siming#; Kou, Xiaoxue; Zhu, Fang; Ouyang, Gangfeng*.Embedding Functional Biomacromolecules within Peptide-Directed Metal-OrganicFramework (MOF) Nanoarchitectures Enables Activity Enhancement. Angew. Chem.Int. Ed. 2020, 59, 13947-13954 (VIP paper).
(11) Chen,Guosheng; Kou, Xiaoxue; Huang, Siming; Tong, Linjing; Shen, Yujian;Zhu, Wangshu; Zhu, Fang; Ouyang, Gangfeng*. Modulatingthe Biofunctionality of Metal-Organic Framework-Encapsulated Enzymes throughControllable Embedding Patterns. Angew. Chem. Int. Ed. 2020, 59, 2867-2874 (ESIhighly cited paper).
(12) Huang, Siming; Kou, Xiaoxue; Shen, Jun; Chen, Guosheng*; Ouyang,Gangfeng*. "Armor-Plating" Enzymes with Metal-Organic Frameworks(MOFs), Angewandte Chemie International Edition. Angew. Chem. Int. Ed. 2020, 59,8786-8798 (ESI highly cited paper).
(13) Chen,Guosheng; Huang, Siming; Kou, Xiaoxue; Wei, Songbo; Huang, Shuyao;Jiang, Shuqi; Shen, Jun; Zhu, Fang; Ouyang,Gangfeng*. A Convenient andVersatile Amino-Acid-Boosted Biomimetic Strategy for the NondestructiveEncapsulation of Biomacromolecules within Metal–Organic Frameworks. Angew. Chem.Int. Ed. 2019, 58, 1463 –1467(ESI highly cited paper).
(14) Huang, Anlian; Yang, Huangsheng; Huang, Siming; Chen, Guosheng*; Ouyang,Gangfeng*. Hydrogen-bonded supramolecular crystal: A manual exoskeleton forbioentity. Matter 2023, 6, 2635–2646.
(15) Kou, Xiaoxue; Lin, Yuhong; Shen, Yong; Tong,Linjing; Gao, Rui; Liu, Suya; Huang, Siming; Zhu, Fang; Chen, Guosheng*; Gangfeng Ouyang. Biomimeticphosphohydrolase nanozyme based on defect-engineered metal-organic framework. CCS Chem. 2024, DOI: 10.31635/ ccschem.023.202303541.
(16) Huang, Wei; Yuan, Haitao;Yang, Huangsheng; Tong, Linjing; Gao, Rui; Kou, Xiaoxue; Wang, Jigang*; Ma,Xiaomin; Huang, Siming*; Zhu, Fang; Chen,Guosheng*; Ouyang, Gangfeng. Photodynamic Hydrogen-Bonded BiohybridFramework: A Photobiocatalytic Cascade Nanoreactor for Accelerating DiabeticWound Therapy. JACSAu 2022, 2, 2048-2058.
(17) Huang, Anlian; Tong, Linjing; Kou, Xiaoxue; Gao, Rui;Li, Zhi-Wei*; Huang, Siming*; Zhu, Fang; Chen,Guosheng*; Ouyang, Gangfeng. Structural and Functional Insights intothe Biomineralized Zeolite Imidazole Frameworks. ACS Nano 2023, 17, 24130−24140.
(18) Chen,Guosheng; Kou, Xiaoxue; Huang, Siming; Huang, Shuyao; Zhang, Rui; Liu, Chao; Shen, Jun; Zhu, Fang*;Ouyang, Gangfeng*. Allochroic-Graphene Oxide Linked 3D Oriented SurfaceImprinting Strategy for Glycoproteins Assays. Adv. Funct. Mater. 2018,1804129.
(19) Chen,Guosheng; Fang, Xu’an; Chen, Qing; Zhang, Jin’ge; Zhong, Zhensong; Xu,Jianqiao; Zhu, Fang*; Ouyang, Gangfeng*. Boronic Acid Decorated DefectiveMetal–Organic Framework Nanoreactors for High-Efficiency CarbohydratesSeparation and Labeling. Adv. Funct. Mater. 2017, 27, 1702126.
(20) Chen,Guosheng; Qiu, Junlang; Xu, Jianqiao; Fang, Xu’an; Liu, Yan; Liu,Shuqin; Wei, Songbo; Jiang, Ruifen; Zeng, Feng; Luan, Tiangang; Zhu, Fang*;Ouyang, Gangfeng*. A novel probe based on phenylboronic acid functionalizedcarbon nanotubes for ultrasensitive carbohydrate determination in biofluids andsemisolid biotissues. Chem. Sci. 2016, 7, 1487-1495.
(21) Ye, Niru; Huang, Siming; Yang, Huangsheng; Wu, Tong;Tong, Linjing; Zhu, Fang; Chen,Guosheng*; Ouyang, Gangfeng. Hydrogen-Bonded BiohybridFramework-Derived Highly Specific Nanozymes for Biomarker Sensing. Anal. Chem. 2021, 93, 13981-13989.
(22) Zhong, Ningyi; Gao, Rui; Shen, Yujian; Kou, Xiaoxue;Wu, Jiayi; Huang, Siming*; Chen,Guosheng*; Ouyang, Gangfeng. Enzymes-Encapsulated DefectiveMetal-Organic Framework Hydrogel Coupling with a Smartphone for a PortableGlucose Biosensor. Anal. Chem. 2022, 94, 14385–14393.
(23) Chen,Guosheng; Huang, Siming; Kou, Xiaoxue; Zhang, Jin’ge; Wang, Fuxin; Zhu,Fang*; Ouyang, Gangfeng*. Novel Magnetic Microprobe with Benzoboroxole-ModifiedFlexible Multisite Arm for High-Efficiency cis-Diol Biomolecule Detection. Anal. Chem.2018, 90, 3387-3394.
(24) Kou, Xiaoxue; Tong, Linjing; Shen, Yujian; Zhu,Wangshu; Yin, Li; Huang, Siming*; Zhu, Fang*; Chen, Guosheng*; Ouyang, Gangfeng. Smartphone-assistedrobust enzymes@MOFs-based paper biosensor for point-of-care detection. Biosensors andBioelectronics 2020, 156, 112095.
(25) Wu, Tong; Huang, Siming*; Yang, Huangsheng; Ye, Niru;Tong, Linjing; Chen, Guosheng*;Zhou, Quan*; Ouyang, Gangfeng. Bimetal Biomimetic Engineering UtilizingMetal–Organic Frameworks for Superoxide Dismutase Mimic. ACS Materials Lett., 2022, 4, 4,751-757.
(26) Yang, Huangsheng; Fu, Jiahui; Huang, Wei; Huang, Wu,Tong; Huang, Siming; Chen, Guosheng*;Ouyang, Gangfeng. Self-Propelled, High-Crystalline Hydrogen-Bonded EnzymaticFramework Assembled by Bottom-Up Strategy. Small Structure 2023, 2200346.
(27) Gao. Rui; Zhong, Niyi; Tong, Linjing; Kou, Xiaoxue;Huang, Wei; Yang, Huangsheng; Huang Siming*; Wu, Jiayi; Chen, Guosheng*; Ouyang, Gangfeng. Mechanochemistry-guidedreticular assembly for stabilizing enzymes with covalent organic frameworks. Cell. Rep. Phys.Sci. 2022, 3, 101153.
(28) Gao, Rui; Ye, Niru; Kou, Xiaoxue; Shen, Yujian; Yang,Huangsheng; Wu, Tong; Huang, Siming*; Chen,Guosheng*; Ouyang, Gangfeng. Hierarchically mesoporous Ce-based MOFswith enhanced alkaline phosphatase-like activity for phosphorylated biomarkersensing. Chem.Commun. 2022, 58, 12720-12723 (HOT paper).
