2005年畢業於中國科學技術大學並獲生物學博士學位。其後在合肥微尺度物質科學國家實驗室從事博士後研究。2009年作為優秀人才引進被聘為中國科學技術大學生命科學學院副教授。廣泛從事了細胞膜與細胞骨架動力學、細胞有絲分裂調控及蛋白質修飾調控的生物學研究。自2003年起,發表SCI 文章20餘篇,其中部分刊登在Oncogene, J. Biol. Chem.等國際知名學術期刊上。
研究興趣
1) 蛋白質翻譯後修飾調控
2) 細胞周期調控
3) 膜泡運輸
代表性論文
1. Yu J, Lan J, Wang C, Wu Q, Zhu Y, Lai X, Sun J, Jin C?, Huang H?. PML3 interacts with TRF1 and is essential for ALT-associated PML bodies assembly in U2OS cells. Cancer Lett. 2009 Nov 7. [Epub ahead of print] (? Corresponding author)
2.Yuan K, Li N, Jiang K, Zhu T, Huo Y, Wang C, Lu J, Shaw A, Thomas K, Zhang J, Mann D, Liao J, Jin C?, Yao X?. PinX1 is a novel microtubule-binding protein essential for accurate chromosome segregation. J Biol Chem 2009 284(34):23072-23082 (? Corresponding author)
3.Yuan K, Li N, Huo Y, Yan F, Yang Y, Ward T, Jin C?, Yao X?. Recruitment of separase to mitotic chromosomes is regulated by Aurora B. Cell Cycle 2009 8(9):1433-43. (? Corresponding author)
4.Du J, Cai X, Yao J, Ding X ?, Wu Q, Pei S, Jiang K, Zhang Y, Wang W, Shi Y, Lai Y, Shen J, Teng M, Huang H, Fei Q, Reddy ES, Zhu J, Jin C ?, and Yao X. ? 2008. The mitotic checkpoint kinase NEK2A regulates kinetochore microtubule attachment stability. Oncogene 2008 27 (29): 4107-4114. (? Corresponding author)
5.Cheng Z, Ke Y, Ding X, Wang F, Wang H, Wang W, Ahmed K, Liu Z, Xu Y, Aikhionbare F, Yan H, Liu J, Xue Y, Yu J, Powell M, Liang S, Wu Q, Reddy SE, Hu R, Huang H, Jin C?, and Yao X. ? 2008.Functional characterization of TIP60 sumoylation in UV-irradiated DNA damage response. Oncogene 27, 931-941. (? Corresponding author)
6. Yu J, Lan J, Zhu Y, Li X, Lai X, Xue Y, Jin C?, and Huang H. ? The E3 ubiquitin ligase HECTD3 regulates ubiquitination and degradation of Tara. 2008. Biochem Biophys Res Commun367, 805–812. (? Corresponding author)
7.Liu D, Ding X, Du J, Cai X, Huang Y, Ward T, Yang Y, Hu R, Jin C?, and Yao X. ? 2007. Human NUF2 Interacts with Centromere-associated Protein E and is essential for a stable spindle microtubule-kinetochore attachment. J Biol Chem 282, 21415-21424. (? Corresponding author)
8.Jin C, Cai X, Ma H, Xue Y, Yao J, and Yao X. 2007. An efficient site-directed mutagenesis method for ColE1-type ori plasmid. Analytical Biochemistry 363, 151–153.
9.Jin C, Ge L, Ding X, Chen Y, Zhu H, Ward T, Wu F, Cao X, Wang Q, Yao X. 2006. PKA-mediated protein phosphorylation regulates Ezrin-WWOX interaction. Biochem Biophys Res Commun341, 784-791.
10.Jin C, Zhang Y, Zhu H, Ahmed K, Fu C, and Yao X. 2005. Human Yip1A specifies the localization of Yif1 to the Golgi apparatus. Biochem Biophys Res Commun334, 16–22.