郭紅超

基本情況

教育經歷：

1993-1997中國農業大學套用化學系, 理學學士

1997-2002 中國農業大學套用化學系, 理學博士

工作經歷：

2002-2004 中國科學院上海有機化學研究所, 博士後

2004-2006 德國馬普所(Muelheim), Research Associate

2006-2008 美國加州大學洛杉磯分校, 博士後

2008-2009 美國伊利諾伊大學厄本那-香檳分校, Research Associate

2009-2010 美國加州大學洛杉磯分校, 訪問學者

2010-2011 中國農業大學理學院套用化學系，副教授

2012-至今中國農業大學理學院套用化學系，教授

教學工作：

本科生課程: 《有機化學A》, 《有機化學B》研究生課程: 《專業英語與科技論文寫作》

主要研究方向與項目

研究方向

1. 研究金屬和有機小分子催化的環加成及環化反應，特別是基於1,3-偶極子的高效、高選擇性環加成反應，
發展高效的選擇性合成方法，並利用手性金屬催化劑和手性有機小分子催化劑發展高效和高選擇性的不對
稱合成新方法，研究這些方法在雜環分子及複雜生物活性分子合成中的套用。
2. 合成具有重要生物活性的雜環化合物及天然產物，用於殺蟲劑、除草劑、殺菌劑及植物生長調節劑等的研
究，開展新農藥創製工作。
3. 結合有機化學、生物化學和分子生物學，利用小分子探針研究植物中重要蛋白質的結構和作用機理。
4. 研究農藥的創新合成工藝。

科研項目：

國家自然科學基金; 國家十二五科技攻關項目;教育部博士點基金

發表論文

主要學術論文與獲獎

論文

已在J. Am. Chem. Soc., Angew. Chem. Int. Ed., Chem. Rev., Chem. Commun., Chem. Eur. J., Adv. Synth. Catal., J. Org. Chem., Tetrahedron, Tetrahedron Lett., Synlett, Synthesis等刊物上發表70餘篇論文，總被引1000餘次，

Honglei Liu, Yang Wu, Yan Zhao, Zhen Li, Lei Zhang, Wenjun Yang, Hui Jiang, Chengfeng Jing, Hao Yu, Bo Wang, Yumei Xiao, Hongchao Guo,* “Metal-Catalyzed [6+3] Cycloaddition of Tropone with Azomethine Ylides: A Practical Access to Piperidine-Fused Bicyclic Heterocycles”, J. Am. Chem. Soc. 2014, 136, 2625–2629.
Zhen Li, Hao Yu, Honglei Liu, Lei Zhang, Hui Jiang, Bo Wang, and Hongchao Guo,* “Phosphine-Catalyzed [3+2] Cycloaddition Reactions of Azomethine Imines with Electron-Deficient Alkenes: A Facile Access to Dinitrogen-Fused Heterocycles”, Chem. Eur. J. 2014, 20, 1731–1736.
Zhilin Yang, Hao Yu, Lei Zhang, Hang Wei, Yumei Xiao, Lanzhen Chen, Hongchao Guo,* “PPh₃-Catalyzed Ring-Expansion Reactions of Sulfamate-Derived Cyclic Imines with Acetylenedicarboxylates”, Chem. Asian J. 2014, 9, 313–318
Zhenzhen Gao, Lei Zhang, Zhanhu Sun, Hao Yu, Yumei Xiao,* and Hongchao Guo,* “DABCO-catalyzed [3 + 2] Annulation of Sulfamate-derived Cyclic Imines with Isocyanoacetates: Synthesis of Sulfamate-fused 2-Imidazoline”, Org. Biomol. Chem. 2014, 12, accepted.
Yumei Xiao, Zhanhu Sun, Hongchao Guo,* and Ohyun Kwon,* “Chiral Phosphines in Nucleophilic Organocatalysis”, Beilstein J. Org. Chem. 2014, accepted.
Hao Yu, Lei Zhang, Zhen Li, Honglei Liu, Bo Wang, Yumei Xiao, Hongchao Guo,* “Phosphine-catalyzed [4+2] cycloaddition of sulfamate-derived cyclic imines with allenoates: synthesis of sulfamate-fused tetrahydropyridines”, Tetrahedron 2014, 70, 340–348.
Zhen Li, Hao Yu, Lei Zhang, Honglei Liu, Risong Na, Qinghua Bian,* Min Wang,* Hongchao Guo,* “Thermal [3+2] cycloaddition reaction of N-acyliminophenanthridinium betaine with allenoates: Facile access to phenanthridine-fused tetracyclic heterocycles”, Lett. Org. Chem. 2014, 11, 220–224.
Lei Zhang, Hao Yu, Zhilin Yang, Honglei Liu, Zhen Li, Junhong Guo, Yumei Xiao, Hongchao Guo,* “Phosphine-catalyzed [3+2] cycloaddition of Morita-Baylis-Hillman carbonates with sulfamate-derived cyclic imines”, Org. Biomol. Chem. 2013, 11, 8235–8240.
Hao Yu, Lei Zhang, Zhilin Yang, Zhen Li, Yan Zhao, Yumei Xiao, Hongchao Guo,* “Phosphine-Catalyzed [3+2] Cycloaddition of Sulfamate-Derived Cyclic Imines with Allenoate: Synthesis of Sulfamate-Fused Dihydropyrroles”, J. Org. Chem. 2013, 78, 8427–8436.
Hongchao Guo,* Honglei Liu, Fu-Lin Zhu, Risong Na, Hui Jiang, Yang Wu, Lei Zhang,Zhen Li, Hao Yu, Bo Wang, Yumei Xiao, Xiang-Ping Hu,* Min Wang, “Enantioselective Copper-Catalyzed [3+3] Cycloaddition of Azomethine Ylides with Azomethine Imines”, Angew. Chem. Int. Ed. 2013, 52, 12641–12645.
Lei Zhang, Chengfeng Jing, Honglei Liu, Bo Wang, Zhen Li, Hui Jiang, Hao Yu, Hongchao Guo*, “Thermal [3+2] Cycloaddition of Aromatic Azomethine Imines with Allenoates”, Synthesis 2013, 45, 53–64.
Changkui Fu, Chongyu Zhu, Shiqi Wang, Honglei Liu, Yun Zhang, Hongchao Guo, Lei Tao*, Yen Wei*, “One-pot synthesis of optically active polymer via concurrent cooperation of enzymatic resolution and living radical polymerization”, Polym. Chem. 2013, 4, 264–267.
Yang Wu, Hongchao Guo,* “Synthesis of allenoates”, Chemical Reagents 2013, 35, 1085–1088.
Risong Na, Bo Wang, Honglei Liu, Qinghua Bian, Jiangchun Zhong, Min Wang* and Hongchao Guo*, “Synthesis and Application of Novel Dithiane Alcohol Ligand Based on Chiral Cyclopropane-backbone for Asymmetric Ethylation of Aromatic Aldehydes”, Lett. Org. Chem. 2012, 9, 622–627.
Hui Jiang, Risong Na, Lei Zhang, Honglei Liu, Zhen Li, Bo Wang, Hongchao Guo*, “Samarium Diiodide Mediated Highly Diastereoselective Conjugate Reduction of the alpha,beta-Unsaturated Ester Moiety in Heterocyclic Compounds”, Synthesis 2012, 44, 3633–3638.
Chengfeng Jing, Risong Na, Honglei Liu, Lei Zhang,Jun Liu, Min Wang, Jiangchun Zhong,* Ohyun Kwon, and Hongchao Guo*, “Phosphine-catalyzed [3+2] and [4+3] Annulation Reactions of C,N-Cyclic Azomethine Imines with Allenoates”, Adv. Synth. Catal. 2012, 354, 1023–1034.
Risong Na, Zhen Li, Honglei Liu, Jun Liu, Ming-An Wang, Min Wang, Jiangchun Zhong and Hongchao Guo,* “Thermal [3+2] Cycloaddition Reaction of Azomethine Imines with Allenoates for Dinitrogen-fused Heterocycles”, Tetrahedron 2012, 68, 2349–2356.
Jun Liu, Honglei Liu, Risong Na, Guiyong Wang, Min Wang, Jiangchun Zhong* and Hongchao Guo,* “Phosphine-Catalyzed [3+2] and [3+3] Annulations of Azomethine Imines with Ethyl 2-Butynoate”, Chem. Lett. 2012, 41, 218–230.
Xi Wu, Risong Na, Honglei Liu, Jun Liu, Min Wang, Jiangchun Zhong,* Hongchao Guo,* “Sequential [3+2] Cycloaddition/Rearrangement Reaction of Imidazolone Nitrones and Allenoates for the Efficient Synthesis of Functionalized Imidazolidinone”, Tetrahedron Lett.2012, 53, 342–344.
Hongchao Guo, Kuiling Ding,* “Self-Supported Chiral Catalysts for Heterogeneous Asymmetric Catalysis”, Chimia 2011, 65, 932–938.
Risong Na, Chengfeng Jing, Qihai Xu, Hui Jiang, Xi Wu, Jiayan Shi, Jiangchun Zhong, Min Wang, Diego Benitez, Ekaterina Tkatchouk, William A. Goddard, III, Hongchao Guo,* Ohyun Kwon,* “Phosphine-Catalyzed Annulations of Azomethine Imines: Allene-Dependent [3+2], [3+3], [4+3], and [3+2+3] Pathways”, J. Am. Chem. Soc. 2011, 133, 13337–13348.
Bing Zheng, Min Wang, Zhiyuan Li, Qinghua Bian, Jianyou Mao, Shuoning Li, Shangzhong Liu, Mingan Wang, Jiangchun Zhong,* Hongchao Guo,* “Asymmetric Henry reaction catalyzed by a Zn–amino alcohol system”, Tetrahedron: Asymmetry 2011, 22, 1156–1160.
Jing Nie, Hongchao Guo, Dominique Cahard, Jun-An Ma,* “Asymmetric Construction of Stereogenic Carbon Centers Featuring a Trifluoromethyl Group from Prochiral Trifluoromethylated Substrates”, Chem. Rev. 2011, 111, 455–529.
Zhiyuan Li, Min Wang, Qinghua Bian, Bing Zheng, Jianyou Mao, Shuoning Li, Shangzhong Liu, Ming-an Wang, Jiangchun Zhong,* Hongchao Guo,* “Highly Enantioselective Addition of Trimethylsilylacetylene to Aldehydes Catalyzed by a Zinc-Amino-Alcohol Complex”, Chem. Eur. J. 2011, 17, 5782–5786.
Hongchao Guo, Kuiling Ding, “Indium Tribromide”, Encyclopedia of Reagents for Organic Synthesis, 2011.
Hongchao Guo, Kuiling Ding, “Self-Supported Chiral Catalysts”, In Catalytic Methods in Asymmetric Synthesis: Advanced Materials, Techniques, and Applications, First Edition. Michelangelo Gruttadauria, Franceso Giacalone, Eds., John Wiley & Sons, Inc. 2011, Chapter 5, p.257–290.
Hongchao Guo, Qihai Xu, Ohyun Kwon,* “Phosphine-Promoted [3+3] Annulation of Aziridines with Allenoates: A Facile Entry into Highly Functionalized Tetrahydropyridines”, J. Am. Chem. Soc. 2009, 131, 6318–6319. This article was selected by the Editorial Board of Synfacts for its important insights, Synfacts 2009, 748, was also highlighted by Chemtracts, Chemtracts-Organic Chemistry 2010, 23, 111–114.
Manfred T. Reetz*, Hongchao Guo, Jun-An Ma, Richard Goddard, Richard J. Mynott, “Helical Triskelion Monophosphites as Ligands in Asymmetric Catalysis”, J. Am. Chem. Soc. 2009, 131, 4136–4142.
Bing Zheng, Shicong Hou, Zhiyuan Li, Hongchao Guo, Jiangchun Zhong*, Min Wang*, “Enantioselective synthesis of quaternary stereogenic centers through catalytic asymmetric addition of dimethylzinc to alpha-ketoesters with chiral cis-cyclopropane-based amide alcohol as ligand”, Tetrahedron: Asymmetry 2009, 20, 2125–2129.
Hongchao Guo, Kuiling Ding,* “New Advance in Combinatorial Asymmetric Catalysis”, In New Concepts and Methods in Asymmetric Catalysis”, K. L. Ding, Q. H. Fan, Eds., Chemical Industry Press, Beijing, 2009, Chapter 14, p.431–463.

郭紅超

基本介紹