郭敏,博士,教授,博士生導師。
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研究方向與興趣:長期從事稻瘟病菌發育調控、稻瘟病菌與水稻互作分子機理研究。主要研究方向:稻瘟病菌與水稻互作分子機制:以模式菌株Guy11為研究材料,挖掘調控稻瘟病菌生長與致病的關鍵基因,解析稻瘟病菌克服寄主免疫反應的分子機制,以揭示稻瘟病菌致病照市背分子機制。安徽省稻瘟病菌遺傳多樣性及變異分子機制:解析安徽地區稻瘟病菌種群動態變化機制,揭示品種布局、氣候因素、耕作制度等外部因素對自然界稻瘟病菌小種變異的影響機理。 歡迎植保、農學、園藝、生科等專業的同汗阿背兆學報考本實驗室研究生。 主講課程:專業核心課程:《普通植物病理學》《農業植物病理學》 專業選修宙趨嘗料課程:《植物病原真菌學》《植保生物技術》 科研情況:國家自然科學基金面上項目,《F-box蛋白MoGrr1調控稻瘟病菌細胞壁發育的分子機制研究》(31671976)、2017.01-2020.12、項目主持人;安徽省自然科學基金青年基金項目拜獄,《兩個新的F-box蛋白調控稻瘟病菌生長發育的分子機制研究》(1608085QC49),2016.07-2018.06,項目主持人;安徽省高校優秀青年人才支持計畫重點項目,《Morak1調控稻瘟病菌生長發育及致病的作用機制》(gxyqZD2016037),2016.01-2018.12,項目主持人;安徽農業大學優秀人才基金(青年學術新秀),2015.05-2018.04,項目主持人。高等學校全國優秀博士學位論文作者專項資金,《Myosin蛋白調控稻瘟病菌生長發育的分子機制》(201470)、2014.01-2017.12、已結題、項目主持人;國家自然科學基金青年基金項目,《PMT 蛋白家族基因在稻瘟病菌生長發育及致病過程中作用機制研究》(31101401)、2012.01-2014.12、已結題、項目主持人;國家公益性行業(農業)科研專項基金,《油料作物菌核病綜合防控技術研究與示範推廣》(201103016)、2011.1-2015.12、參與。國家公益性行業(農業)科研專項基金,《作物疫病監測防控技術研究與示範》(201303018)、2013.1-2017.12、參與。 獎勵與榮譽: 教學與科研: 1. 安徽省高等學校教學成果獎 三等獎(排名第4,2017) 2. 安徽農業大學教學成果獎 三等獎(排名第5,2017) 3. 安徽農業大學教學成果獎 二等獎(排名第6,2016) 4. 安徽農業大學首批青年學術新秀(2015) 5. 全國百篇優秀博士學位論文獲得者(教育部、國務院學位委員會,2012) 本科生與研究生培養: 1. 首屆“全國植物生產類大學生實踐創新論壇”科技論文 二等獎(指導教師,2013) 2. 第十三屆“挑戰杯”全國大學生課外學術科技作品競賽 三等獎(指導教師,2013) 3. 第五屆安徽斷設挨省挑戰杯科技作品競才犁再賽 特等獎(獲優秀指導教師,2013) 4. 安徽農業大學本科生校級優秀畢業論文(設計)(2013) 5. 指導研究生獲2015年、2016年、2017年國家獎學金3項 代表性論文:1. Pan Y., Pan R., Tan L., Zhang Z., Guo M*. (2018) Pleiotropic roles of O-mannosyltransferase MoPmt4 in development and pathogenicity of Magnaporthe oryzae, Current Genetics,DOI:10.1007/s00294-018-0864-2.(IF 3.764,Correspondence author) 2.Guo M., Tan L., Nie X., Zhang Z. (2017) A Class-II Myosin Is Required for Growth, Conidiation, Cell wall integrity and Pathogenicity of Magnaporthe oryzae, Virulence, 8(7)1335–1354. (IF 5.418) 3. Guo M., Zhu X., Li H., Tan L., Pan Y. (2016) Development of a novel strategy for fungal transformation based on a mutant locus conferring carboxin-resistance in Magnaporthe oryzae, AMB Express, 6:57. (IF 2.167) 4. Guo M., Tan L., Nie X., Zhu X., Pan Y., Gao, Z. (2016) The Pmt2p-mediated protein O-Mannosylation is required for morphogenesis, adhesive properties, cell wall integrity and full virulence of Magnaporthe oryzae, Frontiers in Microbiology,7:630. (IF 4.165) 5. Guo M., Gao F., Zhu X., Nie X., Pan Y., Gao, Z. (2015). MoGrr1, a novel F-box protein, is involved in conidiogenesis and cell wall integrity and is critical for the full virulence of Magnaporthe oryzae, Applied Microbiology and Biotechnology, 99:8075-8088. (IF 3.376) 6. Guo M., Kilaru S., Schuster M., Latz M.,Steinberg G. (2015). Fluorescent markers for the Spitzenkörper and exocytosis in Zymoseptoria tritici, Fungal Genetics and Biology 79:158–165. (IF 2.933) 7. Guo M, Pan Y, Dai Y, Gao ZM. (2014). First report of brown blight disease caused by Colletotrichum gloeosporioides on Camellia sinensis in Anhui Province, China. Plant Disease, 98(2): 284. (IF 3.192) 8. Guo M, Pan Y, Dai Y, Gao ZM. (2013). First report of leaf spot caused by Colletotrichum spaethianum on Peucedanum praeruptorum in China. Plant Disease, 97(10):1380. (IF 3.192) 9. Guo M, Pan Y, Gao Z. (2012). First report of medical tree peony root rot caused by Fusarium solani in Tongling, China. Plant Disease, 96(6):909. (IF 3.192) 10. Guo M., Chen Y., Du Y., Dong Y., Guo W., Zhai S, Zhang H., Dong S., Zhang Z, Wang Y, Wang P, Zheng X.(2011). The bZIP transcription factor MoAP1 mediates the oxidative stress response and is critical for pathogenicity of the rice blast fungus Magnaporthe oryzae. PLoS Pathogen 7(2): e1001302. (IF 9.08) 11. Guo, M., Guo, W., Chen, Y., Dong, S., Zhang, X., Zhang, H., Song, W., Wang, W., Wang, Q., Lv, R., Zhang, Z., Wang, Y., Zheng, X. (2010). The basic leucine zipper transcription factor Moatf1 mediates oxidative stress responses and is necessary for full virulence of the rice blast fungus Magnaporthe oryzae. Mol Plant Microbe Interact 23:1053-1068. (IF 4.45) 12. Li X., Guo M., Xu D., Chen F., Zhang H., Pan Y., Gao Z (2015) The nascent polypeptide associated complex alpha subunit regulates the polygalacturonases expression negatively and influences the pathogenicity of Sclerotinia sclerotiorum. Mycologia, 107, 1130-1137. (IF: 2.638) 13. Kilaru S., Schuster M., Latz M., Guo M., Steinberg G. (2015).Fluorescent markers of the endocytic pathway in Zymoseptoria tritici. Fungal Genetics and Biology 79:150–157 (IF 2.933) 14. Schuster M., Kilaru S., Guo M., Sommerauer M., Lin C., Steinberg G. (2015). Red fluorescent proteins for imaging Zymoseptoria tritici during invasion of wheat. Fungal Genetics and Biology 79:132–140 (IF 2.933) 15. Zhang HF, Zhao Q, Guo XX, Guo M, Qi ZQ, Tang W, Ye WW, Zheng XB, Wang P, Zhang ZG (2014). Pleiotropic function of the putative Zinc-finger protein MoMsn2 in Magnaporthe oryzae. Mol Plant Microbe Interact 27: 446-460 (IF 4.145) 16. Chen, Y., Zhai, S., Zhang, H., Zuo, R., Wang, J., Guo, M., Zheng, X., Wang, P., and Zhang, Z. (2014). Shared and distinct functions of two Gti1/Pac2 family proteins in growth, morphogenesis and pathogenicity of Magnaporthe oryzae. Environ Microbiol 16:788-801. (IF 5.932) 17. Dou X, Wang Q, Qi Z, Song W, Wang W, Guo M, Zhang HF, Zhang ZG, Wang P, Zheng X. (2011). MoVam7, a conserved SNARE component involved in vacuole assembly, is required for growth, endocytosis, chitin distribution, ROS accumulation, and pathogenesis of Magnaporthe oryzae. PLoS One 6:e16439 (IF 3.05) 18. Zhang H, Liu K, Zhang X, Tang W, Wang J, Guo M, Zhao Q, Zheng X, Wang P, Zhang Z. (2011). Two phosphodiesterase genes, PDEL and PDEH, regulate development and pathogenicity by modulating intracellular cyclic AMP levels in Magnaporthe oryzae. PLoS One 6: e17241 (IF 3.05) 19. Zhang H., Zhang X., Liu K., Song W., Zhao Q., Dong Y., Guo M., Zheng X., and Zhang Z. (2010). A two-component histidine kinase, MoSLN1, is required for cell wall integrity and pathogenicity of the rice blast fungus, Magnaporthe oryzae. Curr Genet 56:517-528. (IF 3.385) 20. Song W., Dou X., Qi Z., Wang Q., Zhang X., Zhang H., Guo M., Dong S., Zhang Z., Wang P., and Zheng X. (2010). R-SNARE Homolog MoSec22 Is Required for Conidiogenesis, Cell Wall Integrity, and Pathogenesis of Magnaporthe oryzae. PLoS One 5:e13193. (IF 3.05) 21. Li P, Cao S, Dai YL, Li XL, Xu DF, Guo M, Gao ZM. (2012). Genetic diversity among isolates of Photophthora capsici in Anhui based on ISSR-PCR markers. Genetics and Molecular Research, 11 ( 12 ): 4285-4296. 22. 高飛, 孔 亮, 郭敏, 高智謀(2014)稻瘟病菌磷酸甘露糖基轉移酶(PMT)蛋白家族基因結構特徵分析, 安徽農業大學學報,41(6):1027-1032(通訊作者) 23. 喻海峰, 高飛, 朱小蕾, 高智謀, 郭敏(2013)稻瘟病菌Mofbox基因缺失突變體構建及生物學表型分析, 安徽農業大學學報, 40(5):751-757(通訊作者) |