郭成辰,江蘇常州人,西湖大學特聘研究員,功能生物材料實驗室負責人。
基本介紹
- 中文名:郭成辰
- 國籍:中國
- 出生地:江蘇常州
- 畢業院校:南京大學化學化工學院
人物經歷,研究方向,代表論文,
人物經歷
2011年6月本科畢業於南京大學化學化工學院,獲理學學士學位;
2017年5月博士畢業於亞利桑那州立大學分子科學學院,獲化學博士學位。
2017年5月起於美國麻省塔夫茨大學生物工程系進行博士後研究。
將於2020年秋加入西湖大學工學院任特聘研究員/博導(獨立PI),組建“功能生物材料”實驗室。
研究方向
郭成辰博士的研究興趣主要為功能生物高分子材料的設計、製備和生物醫學套用;同時研究興趣也涉及天然生物高分子材料的結構和性能、納米材料的表界面化學、液體/固體核磁共振波譜等。迄今,所開發的一系列蛋白基生物材料被套用於骨修復、組織工程等套用,並且首次實現了再生蠶絲蛋白的熱塑性加工。
代表論文
1. Chengchen Guo†, Chunmei Li†, Hiep V. Vu, Philip Hanna, Aron Lechtig, Yimin Qiu, Xuan Mu, Shengjie Ling, Ara Nazarian, Samuel Lin, David L. Kaplan, Thermoplastic Moulding of Regenerated Silk. Nat. Mater. 2020, 19, 102-108. († equal contribution)
2. Chunmei Li†, Chengchen Guo†, Vincent Fitzpatrick, Ahmed Ibrahim, Myrthe Zwierstra, Philip Hanna, Aron Lechtig, Ara Nazarian, Samuel Lin, and David Kaplan, Design of biodegradable implantable devices towards clinical translation. Nat. Rev. Mater. 2020, 5, 61-81. († equal contribution)
3. Ying Chen†, Chengchen Guo†, Eleana Manousiouthakis, Xiuli Wang, Dana M. Cairns, Terrence Roh, Chuang Du, David L. Kaplan, Bi-layered Tubular Microfiber Scaffolds as Functional Templates for Engineering Human Intestinal Smooth Muscle Tissue. Adv. Funct. Mater. 2020, 2000543. († equal contribution)
4. Chengchen Guo, Chunmei Li, Xuan Mu, David L. Kaplan, Engineering Silk Materials: From Natural Spinning to Artificial Processing. Appl. Phys. Rev. 2020, 7, 011313
5. Chengchen Guo, Chunmei Li, David L. Kaplan, Enzymatic Degradation of Bombyx mori Silk Materials: A Review. Biomacromolecules 2020, 21, 5, 1678-1686
6. Chengchen Guo*, Jin Zhang, Jacob S Jordan, Xungai Wang, Robert W Henning, Jeffery L Yarger, Structural Comparison of Various Silkworm Silks: An Insight into the Structure-Property Relationship. Biomacromolecules 2018, 19, 906. (* Co-corresponding author)
7. Chengchen Guo*, Jeffery L Yarger, Characterizing Gold Nanoparticles by NMR Spectroscopy. Magn. Reson. Chem. 2018, 11, 1074. (* Co-corresponding author)
8. Chengchen Guo*, Jacob S. Jordan, Jeffery L. Yarger, Gregory P. Holland, Highly Efficient Fumed Silica Nanoparticles for Peptide Bond Formation: Converting Alanine to Alanine Anhydride. ACS Appl. Mater. Interfaces 2017, 9, 17653. (* Co-corresponding author)
9. Chengchen Guo, Jin Zhang, Xungai Wang, Anh Tuan Nguyen, Xiang Yang Liu, David L Kaplan, Comparative Study of Strain-Dependent Structural Changes of Silkworm Silks: Insight into the Structural Origin of Strain-Stiffening. Small 2017, 13, 1702266.
10. Chengchen Guo, Gregory P. Holland, Jeffery L. Yarger, Lysine-capped Silica Nanoparticles: A solid-state NMR Spectroscopy Study. MRS Advance 2016, 31, 2261.
11. Chengchen Guo, Gregory P. Holland, Alanine Adsorption and Thermal Condensation at the Interface of Fumed Silica Nanoparticles: A Solid-state NMR Investigation. J. Phys. Chem. C 2015, 119, 25663.
12. Chengchen Guo, Genevieve N. Hall, John B. Addison, Jeffery L. Yarger, Gold Nanoparticle-doped Silk Film as Biocompatible SERS substrate. RSC Adv. 2015, 5, 1937.
13. Chengchen Guo, Gregory P. Holland, Investigating Lysine Adsorption on Fumed Silica Nanoparticles. J. Phys. Chem. C 2014, 118, 25792.