邱立朋，男，1984年10月出生，博士，現任江南大學藥學院副教授。
基本介紹
- 中文名：邱立朋
- 學位/學歷：博士
- 職業：教師
- 專業方向：納米藥物載體；藥物新劑型；生物醫學材料
- 任職院校：江南大學
個人經歷,主講課程,研究方向,學術成果,榮譽獎項,
個人經歷
學習經歷
2011.9-2014.6 瀋陽藥科大學， 藥劑學，理學博士；
2008.9-2011.6 瀋陽藥科大學， 藥劑學，理學碩士；
2004.9-2008.7 泰山醫學院贈承， 藥學， 理學學士；
科研工作經歷
2014.07-2017.05，江南大學藥學院，校聘副教授。
2017.05-至今， 江南大學藥學院，副教授，碩士生導師。
2019.09-至今， 山東大符邀妹汽學-翔宇藥業股份有限民地墊公司，博士後。
主講課程
本科生：藥劑學（江南大學卓越課程、江蘇省線上課程）、現代藥物遞送技術
碩士研究生：化學生物學、製藥技術研究進展
研究方向
納米藥物載體；藥物新劑型；生物醫學材料
學術成果
近年來獲得的學術科研成果
近年來發表SCI論文20餘篇，主持國家自然科學基金等6項，申請發明專利8項。
近年來主要研究課題
[1]基於Heparosan多糖長循環多功能聚合物膠束的構建及作用機制研究（81503007）阿棗挨辨，國家青年科學基金項目，主持。
[2]抗癌中藥創新納米製劑的製備及作用研究，中國博士後科學基金面上（一等資助）項目，主持。
[3] pH敏感靶向囑囑漿聚合物膠束及其逆轉多藥耐藥的研究（JUSRP11565），中央高校基本科研業務經費培育項目，主持腳束祖。
[4]膠原基修復凝膠的研發，企業項目朵試漏，主持。
[5]緩釋微丸的研發，企業項目，主持。
[6]玻尿酸凍乾品的研發，企業項目，主持。
【近年來主要論文代表作】
[1]Qiu L, Qiao M, Chen Q,et al.Enhanced Effect of pH-Sensitive Mixed Copolymer Micelles for Overcoming Multidrug Resistance of Doxorubicin.Biomaterials. 2014,35(37):9877-9887.
[2]Qiu L, Li Z, Qiao M, et al. Self-assembled pH-responsive Hyaluronic Acid-g-poly (L-histidine) Copolymer Micelles for Targeted Intracellular Delivery of Doxorubicin. Acta Biomaterialia. 2014, 10 (5): 2024-2035.
[3]Qiu L, Hu Q, Cheng L,et al.cRGDyK modified pH responsive nanoparticles for specific intracellular delivery of doxorubicin.Acta Biomaterialia. 2016,30:285-298.
[3]Chen Q, Long M,Qiu L*, et al.Decoration of pH-sensitive copolymer micelles with tumor-specific peptide for enhanced cellular uptake of doxorubicin.Int J Nanomedicine. 2016:11 5415–5427.
[4]Qiu L, Zhu M, HuangY, et al. Mechanisms of cellular uptake with hyaluronic acid-octadecylamine micelles as drug delivery nanocarriers. RSC advances, 2016, 6, 9896–39902.
[5]Qiu L, Zhu M, Gong K, et al.pH-Sensitive degradable polymeric micelles for bio-triggered targeted anti-tumor drug delivery, Journal of Controlled Release.2017, 259: e86-e87.
[6]Qiu L, Zhu M, Gong K, et al. pH-triggered degradable polymeric micelles for targeted anti-tumor drug delivery. Mater Sci Eng C Mater Biol Appl. 2017, 78: 912-922.
[7]Ahmed KS, Hussein SA, Ali AH, Korma SA,Lipeng Q*, Jinghua C*.Liposome: composition, characterisation, preparation, and recent innovation in clinical applications.J Drug Target. 2018,15:1-20.
[8]Qiu L, Ge L, Long M, et al.Designing heparan sulfate-based biocompatible polymers and their application for intracellular stimuli-sensitive drug delivery.Mater Sci Eng C Mater Biol Appl. 2019,94:465-476.
[9]Ahmed KS, Shan X, Mao J,Qiu L*, Chen J*.Derma roller® microneedles-mediated transdermal delivery of doxorubicin and celecoxib co-loaded liposomes for enhancing the anticancer effect.Mater Sci Eng C Mater Biol Appl. 2019,99:1448-1458.
[10]Shan X,Mao J,Long M,Ahmed KS,Sun C,Qiu L*, Chen J*.Influence of polyethylene glycol molecular weight on the anticancer drug delivery of pH-sensitive polymeric micelle.J Appl Polym Sci. 2019,136 (32):47854.
[11]Qiu L, Shan X, Long M,et al.Elucidation of cellular uptake and intracellular trafficking of heparosan polysaccharide-based micelles in various cancer cells.Int J Biol Macromol. 2019,130:755-764.
[12]Ahmed KS, SunC, Shan X, Mao J,Qiu L*, Chen J*.Liposome-based codelivery of celecoxib and doxorubicin hydrochloride as a synergistic dual-drug delivery system for enhancing the anticancer effect.J Liposome Res. 2019,1-12.
[13]Qiu L, Ge L, Long M, et al.Redox-responsive biocompatible nanocarriers based on novel heparosan polysaccharides for intracellular anticancer drug delivery.Asian J Pharm Sci. 2020, 15(1):83-94.
申請國家發明專利
[1]一種複方坦洛新和非那雄胺控釋片及製備方法.王東凱,邱立朋.公開號: CN 101703512A.
[2]複方坦洛新和非那雄胺緩釋膠囊及其製備方法.王東凱,邱立朋.公開號: CN101703511A.
[3]一種坦洛新和非那雄胺複方緩釋片及其製備方法.王東凱,邱立朋. CN 101703510A.
[4]一種肝素前體多糖聚合物及其製備方法和套用.邱立朋,陳敬華,葛璐,毛靜.公開號: CN201811562526.3.
榮譽獎項
全國挑戰杯優秀指導教師
江南大學“青年至善學者”
高等學校科學研究技術進步二等獎
中國輕工業聯合會科技進步二等獎
中國商業聯合會科技進步一等獎
[3]Chen Q, Long M,Qiu L*, et al.Decoration of pH-sensitive copolymer micelles with tumor-specific peptide for enhanced cellular uptake of doxorubicin.Int J Nanomedicine. 2016:11 5415–5427.
[4]Qiu L, Zhu M, HuangY, et al. Mechanisms of cellular uptake with hyaluronic acid-octadecylamine micelles as drug delivery nanocarriers. RSC advances, 2016, 6, 9896–39902.
[5]Qiu L, Zhu M, Gong K, et al.pH-Sensitive degradable polymeric micelles for bio-triggered targeted anti-tumor drug delivery, Journal of Controlled Release.2017, 259: e86-e87.
[6]Qiu L, Zhu M, Gong K, et al. pH-triggered degradable polymeric micelles for targeted anti-tumor drug delivery. Mater Sci Eng C Mater Biol Appl. 2017, 78: 912-922.
[7]Ahmed KS, Hussein SA, Ali AH, Korma SA,Lipeng Q*, Jinghua C*.Liposome: composition, characterisation, preparation, and recent innovation in clinical applications.J Drug Target. 2018,15:1-20.
[8]Qiu L, Ge L, Long M, et al.Designing heparan sulfate-based biocompatible polymers and their application for intracellular stimuli-sensitive drug delivery.Mater Sci Eng C Mater Biol Appl. 2019,94:465-476.
[9]Ahmed KS, Shan X, Mao J,Qiu L*, Chen J*.Derma roller® microneedles-mediated transdermal delivery of doxorubicin and celecoxib co-loaded liposomes for enhancing the anticancer effect.Mater Sci Eng C Mater Biol Appl. 2019,99:1448-1458.
[10]Shan X,Mao J,Long M,Ahmed KS,Sun C,Qiu L*, Chen J*.Influence of polyethylene glycol molecular weight on the anticancer drug delivery of pH-sensitive polymeric micelle.J Appl Polym Sci. 2019,136 (32):47854.
[11]Qiu L, Shan X, Long M,et al.Elucidation of cellular uptake and intracellular trafficking of heparosan polysaccharide-based micelles in various cancer cells.Int J Biol Macromol. 2019,130:755-764.
[12]Ahmed KS, SunC, Shan X, Mao J,Qiu L*, Chen J*.Liposome-based codelivery of celecoxib and doxorubicin hydrochloride as a synergistic dual-drug delivery system for enhancing the anticancer effect.J Liposome Res. 2019,1-12.
[13]Qiu L, Ge L, Long M, et al.Redox-responsive biocompatible nanocarriers based on novel heparosan polysaccharides for intracellular anticancer drug delivery.Asian J Pharm Sci. 2020, 15(1):83-94.
申請國家發明專利
[1]一種複方坦洛新和非那雄胺控釋片及製備方法.王東凱,邱立朋.公開號: CN 101703512A.
[2]複方坦洛新和非那雄胺緩釋膠囊及其製備方法.王東凱,邱立朋.公開號: CN101703511A.
[3]一種坦洛新和非那雄胺複方緩釋片及其製備方法.王東凱,邱立朋. CN 101703510A.
[4]一種肝素前體多糖聚合物及其製備方法和套用.邱立朋,陳敬華,葛璐,毛靜.公開號: CN201811562526.3.
榮譽獎項
全國挑戰杯優秀指導教師
江南大學“青年至善學者”
高等學校科學研究技術進步二等獎
中國輕工業聯合會科技進步二等獎
中國商業聯合會科技進步一等獎
