趙鑫銳，男，博士，江南大學生物工程學院副研究員。
基本介紹
- 中文名：趙鑫銳
- 畢業院校：江南大學
- 學位/學歷：博士
- 職業：教師
- 專業方向：事酵母以及大腸桿菌代謝工程
- 任職院校：江南大學生物工程學院
人物經歷,發表論文,專利成果,
人物經歷
2002-2006 安徽大學，生物科學專業，理科學士
2007-2010 安徽大學，微生物學專業，理科碩士
2010-2014 江南大學，發酵工程專業，工科博士
2014-2016 江南大學，糖化學與糖藥物工程研究室，博士後
2016-2018 韓國KAIST大學，Metabolic & Biomolecular Engineering Laboratory，博士後
發表論文
1. Zhao, X., Choi, K., Lee, S. *, Metabolic engineering of Escherichia coli for secretory production offree haem. Nat. Catal. doi: 10.1038/s41929-018-0126-1.
2. Zhao, X., Park, S., Yang. D., Lee, S. *, Synthetic biology for natural compounds. Biochemistry doi:10.1021/acs.biochem.8b00569 (IF: 2.99).
3. Yang, M., Hong, H., Liu, S., Zhao, X., Wu, Z. *, 2018. Immobilization of Staphylococcus aureussortase A on chitosan particles and its applications in peptide-to-peptide ligation and peptide cyclization. Molecules 23 (1), 192 (IF: 3.10)
4. Zhao, X., Hong, H., Cheng, X., Liu, S., Deng, T., Guo, Z., Wu, Z. *, 2017. One-step purification andimmobilization of extracellularly expressed sortase A by magnetic particles to develop a robust andrecyclable biocatalyst. Sci. Rep. 7, doi: 10.1038/s41598-017-06856-y. (IF: 4.26)
5. Zhao, X., Hong, H., Wu, Z. *, 2017. Efficient extracellular expression of transpeptidase sortase A inPichia pastoris. Protein Expr. Purif. 133, 132-138. (IF: 1.35)
6. Wu, Z. *, Hong, H., Zhao, X., Wang, X., 2017. Efficient expression of sortase A from Staphylococcusaureus in Escherichia coli and its enzymatic characterizations. Bioresour. Bioprocess. 4, 13.
7. Wu, Z. *, Liu, S., Cheng, X., Zhao, X., Hong, H., 2017. High yield synthesis of cyclic analogues ofantibacterial peptides P-113 by Sortase A-mediated ligation and their conformation studies. Chin. Chem. Lett. 28, 553-557. (IF: 1.93)
8. Wu, Z. *, Cheng, X., Hong, H., Zhao, X., Zhou, Z., 2017. New potent and selective alpha v beta(3)integrin ligands: Macrocyclic peptides containing RGD motif synthesized by sortase A-mediated ligation. Biorg. Med. Chem. Lett. 27, 1911-1913. (IF: 2.45)
9. Zhao, X., Zou, H., Chen, J., Du, G., Zhou, J. *. 2016. The modification of Gat1p in nitrogen cataboliterepression to enhance non-preferred nitrogen utilization in Saccharomyces cerevisiae. Sci. Rep. 6, doi:10.1038/srep21603. (IF: 5.23)
10. Zhao, X., Zou, H., Du, G., Chen, J., Zhou, J. *. 2015. Effects of nitrogen catabolite repression-relatedamino acids on the flavour of rice wine. J. I. Brewing 121:581-588. (IF: 1.02)
11. Zhao, X., Zou, H., Fu, J., Zhou, J. *, Du, G. *, Chen, J.. 2014. Metabolic engineering of the regulatorsin nitrogen catabolite repression to reduce the production of ethyl carbamate in a model rice wine system. Appl. Environ. Microbiol. 80:392-398. (IF: 3.95)
12. Zhao, S., Zhao, X., Zou, H., Fu, J., Du, G. *, Zhou, J. *, Chen, J.. 2014. Comparative proteomicanalysis of Saccharomyces cerevisiae under different nitrogen sources. J. Proteomics 101:102-112. (IF:4.09)
13. Zhao, X., Zou, H., Fu, J., Chen, J., Zhou, J. *, Du, G. *. 2013. Nitrogen regulation involved in theaccumulation of urea in Saccharomyces cerevisiae. Yeast 30:437-447. (IF: 1.96)
14. Zhao, X., Du, G. *, Zou, H., Fu, J., Zhou, J.*, Chen, J.. 2013. Progress in preventing the accumulationof ethyl carbamate in alcoholic beverages. Trends Food Sci. Technol. 32:97-107. (IF: 4.14)
15. Lv, Y., Zhao, X., Liu, L., Du, G. *, Zhou, J. *, Chen, J.. 2013. A simple procedure for proteinubiquitination detection in Saccharomyces cerevisiae: Gap1p as an example. J. Microbiol. Meth. 94:25- 29. (IF: 2.16)
專利成果
1. 吳志猛，趙鑫銳，洪皓飛. 一種高效分泌表達轉肽酶Sortase A的方法. 專利申請號：201510430763.4
2. 吳志猛，趙鑫銳，洪皓飛，王珣. 一種利用重組大腸桿菌高效生產轉肽酶Sortase A的方法. 專利申請號：201510440032.8
3. 周景文，陳堅，堵國成，呂永坤，趙鑫銳.一種改造調控因子降低酵母尿素積累的方法. 專利申請號：201510810669.1
4. 周景文，陳堅，堵國成，呂永坤，趙鑫銳.一種可降低黃酒發酵中氨基甲酸乙酯積累的方法. 專利申請號：201510812131.4
5. 周景文，陳堅，堵國成，呂永坤，趙鑫銳.一種改造尿素代謝調控途徑降低釀酒酵母尿素積累的方法. 專利申請號：201510816366.0
6. 周景文，陳堅，堵國成，呂永坤，趙鑫銳.一種提高釀酒酵母非偏好型氮源利用的方法. 專利申請號：201510819223.5
