趙欣捷

趙欣捷,女,中國科學院大學專任教師。

基本介紹

  • 中文名:趙欣捷
  • 國籍中國
  • 畢業院校:大連理工大學
  • 學位/學歷:博士
人物經歷,教育背景,工作經歷,科研成果,專利成果,出版信息,科研項目,

人物經歷

教育背景

2002-09--2009-01 中國科學院大連化學物理研究所 博士
1994-09--1998-07 大連理工大學 學士

工作經歷

1998-08~現在, 中國科學院大連化學物理研究所, 副研究員

科研成果

專利成果

( 1 ) 用於診斷多囊卵巢綜合徵的聯合標誌物、試劑盒和系統, 發明, 2014, 第 3 作者, 專利號: 201410018414.7
( 2 ) 一種脂質代謝網路動態研究的方法, 發明, 2013, 第 3 作者, 專利號: 201310091384.8
( 3 ) 一種篩查糖尿病的聯合型代謝標誌物的套用及其試劑盒, 發明, 2019, 第 3 作者, 專利號: 201911218594.2
( 4 ) 一種血清代謝標誌物的用途及檢測試劑盒, 發明, 2019, 第 5 作者, 專利號: 201911004348.7
( 5 ) 用於糖尿病人群中視網膜病變診斷的聯合標誌物及試劑盒, 發明, 2019, 第 5 作者, 專利號: 20190609167.0

出版信息

發表論文
(1) Rapid lipidomic profiling based on ultra-high performance liquid chromatography-mass spectrometry and its application in diabetic retinopathy, ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 2020, 第 5 作者
(2) Pseudotargeted Method Based on Parallel Column Two- Dimensional Liquid Chromatography-Mass Spectrometry for Broad Coverage of Metabolome and Lipidome, ANALYTICAL CHEMISTRY, 2020, 第 4 作者
(3) Muscle-Liver Substrate Fluxes in Exercising Humans and Potential Effects on Hepatic Metabolism, JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2020, 第 5 作者
(4) Identification and regulation of the xenometabolite derivatives cis- and trans-3,4-methylene-heptanoylcarnitine in plasma and skeletal muscle of exercising humans, AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM, 2020, 第 1 作者
(5) A multi-omics investigation of the molecular characteristics and classification of six metabolic syndrome relevant diseases, THERANOSTICS, 2020, 第 1 作者
(6) Removal of false positive features to generate authentic peak table for high-resolution mass spectrometry-based metabolomics study, ANALYTICA CHIMICA ACTA, 2019, 第 4 作者
(7) Metabolomics profiling of metformin-mediated metabolic reprogramming bypassing AMPK alpha, METABOLISM-CLINICAL AND EXPERIMENTAL, 2019, 第 4 作者
(8) Deep Annotation of Hydroxycinnamic Acid Amides in Plants Based on Ultra-High-Performance Liquid Chromatography-High-Resolution Mass Spectrometry and Its In Silico Database, ANALYTICAL CHEMISTRY, 2018, 第 3 作者
(9) Plasma bile acid changes in type 2 diabetes correlated with insulin secretion in two-step hyperglycemic clamp, JOURNAL OF DIABETES, 2018, 第 6 作者
(10) Ion-Pair Selection Method for Pseudotargeted Metabolomics Based on SWATH MS Acquisition and Its Application in Differential Metabolite Discovery of Type 2 Diabetes, ANALYTICAL CHEMISTRY, 2018, 第 5 作者
(11) Metabolomics and transcriptomics profiles reveal the dysregulation of the tricarboxylic acid cycle and related mechanisms in prostate cancer, INTERNATIONAL JOURNAL OF CANCER, 2018, 第 5 作者
(12) Development of a High Coverage Pseudotargeted Lipidomics Method Based on Ultra-High Performance Liquid Chromatography-Mass Spectrometry, ANALYTICAL CHEMISTRY, 2018, 第 6 作者
(13) Comprehensive Strategy to Construct In-House Database for Accurate and Batch Identification of Small Molecular Metabolites, ANALYTICAL CHEMISTRY, 2018, 第 1 作者
(14) Strategy for Comprehensive Identification of Acylcarnitines Based on Liquid Chromatography-High-Resolution Mass Spectrometry, ANALYTICAL CHEMISTRY, 2018, 第 5 作者
(15) Serum Metabolomics Study of Gliclazide-Modified-Release-Treated Type 2 Diabetes Mellitus Patients Using a Gas Chromatography-Mass Spectrometry Method, JOURNAL OF PROTEOME RESEARCH, 2018, 第 3 作者
(16) Development of Urinary Pseudotargeted LC-MS-Based Metabolomics Method and Its Application in Hepatocellular Carcinoma Biomarker Discovery, Journal of Proteome Research , 2015, 第 4 作者
(17) A data preprocessing strategy for metabolomics to reduce the mask effect in data analysis., Front Mol Biosci., 2015, 第 2 作者
(18) Discovery and validation of plasma biomarkers for major depressive disorder classification based on liquid chromatography-mass spectrometry., Journal of Proteome Research , 2015, 第 3 作者
(19) GC/MS-based metabolomic studies reveal key roles of glycine in regulating silk synthesis in silkworm, Bombyx mori., Insect Biochem Mol Biol. , 2015, 通訊作者
(20) Serum metabolomics study of polycystic ovary syndrome based on liquid chromatography-mass spectrometry, Journal of Proteome Research, 2014, 第 1 作者
(21) Serum metabolomics study of the acute graft rejection in human renal transplantation based on liquid chromatography-mass spectrometry, Journal of Proteome Research , 2014, 第 1 作者
(22) Serum metabolomics study and eicosanoid analysis of childhood atopic dermatitis based on liquid chromatography-mass spectrometry, Journal of Proteome Research , 2014, 通訊作者
(23) Serum metabolic profiling study of lung cancer using ultra high performance liquid chromatography/quadrupole time-of-flight mass spectrometry., J Chromatogr B Analyt Technol Biomed Life Sci., 2014, 通訊作者
(24) Serum lipid profiling of patients with chronic hepatitis B, cirrhosis, and hepatocellular carcinoma by ultra fast LC/IT-TOF MS., Electrophoresis., 2013, 第 3 作者
(25) Large-scaled human serum sphingolipid profiling by using reversed-phase liquid chromatography coupled with dynamic multiple reaction monitoring of mass spectrometry: method development and application in hepatocellular carcinoma., J Chromatogr A., 2013, 第 3 作者
(26) Simultaneous extraction of metabolome and lipidome with methyl tert-butyl ether from a single small tissue sample for ultra-high performance liquid chromatography/mass spectrometry., J Chromatogr A., 2013, 通訊作者
(27) Production and release of acylcarnitines by primary myotubes reflect the differences in fasting fat oxidation of the donors., J Clin Endocrinol Metab. , 2013, 第 3 作者
(28) Stable isotope-assisted lipidomics combined with nontargeted isotopomer filtering, a tool to unravel the complex dynamics of lipid metabolism., Anal Chem. , 2013, 第 3 作者
(29) Preanalytical aspects and sample quality assessment in metabolomics studies of human blood., Clin Chem., 2013, 第 4 作者

科研項目

( 1 ) 中德合作發展全脂及代謝組學平台用新代謝生物標誌物的鑑定及其功能表征, 參與, 國家級, 2012-01--2015-12
( 2 ) 代謝小分子標誌物篩選鑑定和套用, 參與, 國家級, 2012-01--2015-12
( 3 ) 大規模非靶向LC-MS代謝組學分析新策略研究, 主持, 國家級, 2020-01--2023-12
( 4 ) 基於LC-MSn的代謝物定性策略研究, 主持, 國家級, 2016-01--2019-12

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