蔡雲飛，男，1986年2月出生，重慶璧山人，理學博士，重慶大學化學化工學院預聘制研究員。主要從事有機合成方法學、藥物化學、材料化學等方面的研究。主持國家自然科學基金青年項目、重慶市科委項目、重慶市人社局留創項目、重慶大學科研啟動基金。
基本介紹
- 中文名：蔡雲飛
- 畢業院校：四川大學
- 學位/學歷：博士
- 專業方向：有機合成方法學、藥物化學、材料化學等
人物經歷,研究方向,學術成果,
人物經歷
2017年10月以青年“百人計畫”加入重慶大學化學化工學院，任特聘研究員、博士生導師。2009年本科畢業於四川大學化學學院，隨後師從馮小明教授留校繼續學習，並於2014年7月獲得博士學位。同年獲得德國洪堡學者獎學金，於2014年8月至2016年10月在德國亞琛工業大學從事博士後研究，2016年10月至2017年10月在沙烏地阿拉伯阿卜杜拉國王科技大學（KAUST）繼續從事博士後研究，合作導師均為Magnus Rueping教授。
研究方向
主要研究方向：有機合成新方法的開發及其在具有生理活性或藥用價值分子合成中的套用。
學術成果
1.Yunfei Cai,Xiaohua Liu,Pengfei Zhou, andXiaomingFeng*， Asymmetric Catalytic Halofunctionalization of α,β-Unsaturated Carbonyl Compounds, J. Org. Chem. 2019,84, 1–13. (Perspective)
2.Yunfei Cai, Yurong Tang, Lulu Fan, Quentin Lefebvre, Hong Hou, and Magnus Rueping*,Heterogeneous Visible-Light Photoredox Catalysis with Graphitic Carbon Nitride for α‑Aminoalkyl Radical Additions, Allylations, and Heteroarylations, ACS Catal. 2018, 8, 9471-9476.
3.YunfeiCai,YurongTang,IulianaAtodiresei,andMagnusRueping*,CatalyticAsymmetricPiancatelliRearrangement:BronstedAcidCatalyzed4π-Electrocyclization fortheSynthesisofMultisubstitutedCyclopentenones,Angew.Chem.Int.Ed.2016, 55,14126–14130.
4.YunfeiCai,XiaohuaLiu,YonghaiHui,JunJiang,WentaoWang,WeiliangChen,LiliLin,andXiaomingFeng*, CatalyticAsymmetricBromoaminationofChalcones:HighlyEfficientSynthesisofChiralα-Bromo-β-AminoKetoneDerivatives,Angew.Chem.Int.Ed.2010,49,6160–6164.(VIPpaper;HighlightedbyAngew.Chem.Int.Ed.2011,50,7734and Synfacts 2010,6,1261.)
5.YunfeiCai,XiaohuaLiu,JunJiang,WeiliangChen,LiliLin,andXiaomingFeng*,AsymmetricChloroaminationReactionofα,β-Unsaturatedγ-KetoEstersandChalcones,J.Am.Chem.Soc. 2011,133,5636–5639.(InvitedtowriteSynstory July,2011;HighlightedbySynfacts 2011,7, 0757.)
6.YunfeiCai, PengfeiZhou,XiaohuaLiu,JiannanZhao,LiliLinandXiaomingFeng*,DiastereoselectivelySwitchableAsymmetricHaloaminocyclizationforthe SynthesisofCyclicSulfamates,Chem.Eur.J.2015,21,6386–6389.
7.YunfeiCai, XiaohuaLiu,PengfeiZhou,YulongKuang,LiliLinandXiaomingFeng*,Iron–CatalyzedAsymmetricHaloaminationReactions,Chem.Commun.2013,49, 8054–8056.
8.YunfeiCai,JunLi,WeiliangChen,MingshengXie,XiaohuaLiu,LiliLin,andXiaomingFeng*,CatalyticAsymmetricSulfenylationofUnprotected3-SubstitutedOxindoles,Org.Lett.2012,14,2726–2729.(HighlightedbySynfacts 2012, 8, 0998.)
9.YunfeiCai,XiaohuaLiu,JunLi,WentaoWang,WeiliangChen,LiliLinandXiaomingFeng*,AsymmetricIodoaminationofChalconesand4-Aryl-4-oxobutenoatesCatalyzedbyaComplexBasedonScandium(III)anda N,N′-DioxideLigand,Chem.Eur.J.2011,17,14916–14921.
10.YunfeiCai,WentaoWang,KeShen,JunWang,XiaoleiHu,LiliLin,XiaohuaLiuandXiaomingFeng*,Highlyenantioselectiveα-chlorinationofcyclicβ-ketoesterscatalyzedbyN,N'-DioxideusingNCSasthechlorinesource,Chem.Commun.2010,46,1250–1252.(HighlightedbySynfacts 2010,0477.)
11.PengfeiZhou,YunfeiCai,XiaZhong,WeiweiLuo,TengfeiKang,JunLi,XiaohuaLiu*,LiliLin,andXiaomingFeng*,CatalyticAsymmetricIntra-andIntermolecularHaloetherificationofEnones:AnEfficientApproachto(−)-Centrolobine,ACSCatal.2016,6,7778–7783.
12.PengfeiZhou,YunfeiCai,LiliLin,XiangjinLian,YongXia,XiaohuaLiuandXiaomingFeng*,AsymmetricSynthesisofSpirocyclicOxindole-FusedTetrahydrothiophenesviaN,N′-Dioxide–Nickel(II)CatalyzedDominoReactionof1,4-Dithiane-2,5-diolwith3-Alkenyloxindoles,Adv.Syn.Cat. 2015,357,695-700.
13.JunLi,YunfeiCai,WeiliangChen,XiaohuaLiu,LiliLin,andXiaomingFeng*,HighlyEnantioselectiveFluorinationofUnprotected3 -SubstitutedOxindoles:One-StepSynthesisofBMS204352(MaxiPost),J.Org.Chem. 2012,77,9148–9155.
14.JunJiang,YunfeiCai,WeiliangChen,LiliLin,XiaohuaLiuandXiaomingFeng*,Enantioselectiveaza-Michaelreactionofhydrazidetochalconesthroughthenonactivatedaminemoietyconjugatedaddition,Chem.Commun. 2011,47,4016–4018.
15.WeiliangChen,YunfeiCai,XuanFu,XiaohuaLiu,LiliLin,andXiaomingFeng*,EnantioselectiveOne-PotSynthesisof2-Amino-4-(indol-3-yl)-4H-Chromenes,Org.Lett.2011,13,4910–4913.
16.KeShen,XiaohuaLiu,YunfeiCai,LiliLin,XiaomingFeng*,FacileandEfficientEnantioselectiveStreckerReactionofKetiminesbyChiralSodiumPhosphate,Chem.Eur.J.2009,15,6008–6014.
17.WeiliangChen,LiliLin,YunfeiCai,YongXia,WeidiCao,XiaohuaLiuandXiaomingFeng*,Catalyticasymmetric[3+2]cycloadditionofaromaticaldehydeswithoxiranesbyC–Cbondcleavageofepoxides:highlyefficientsynthesisofchiral1,3-dioxolanes,Chem.Commun. 2014,50,2161–2163.
18.HuifengYue,LinGuo,Hsuan-HungLiao,YunfeiCai,ChenZhuandMagnusRueping*,CatalyticEsterandAmidetoAmineInterconversion:Nickel-CatalyzedDecarbonylativeAminationofEstersandAmidesbyC−OandC−CBondActivation,Angew.Chem.Int.Ed.2017,56,4282–4285.
19.WeiLi,XiaohuaLiu,XiaoyuHao,YunfeiCai,LiliLin,andXiaomingFeng*,ACatalyticAsymmetricRing-ExpansionReactionofIsatinsandalfa-Alkyl-alfa-Diazoesters:HighlyEfficientSynthesisofFunctionalized2-QuinoloneDerivatives,Angew.Chem.Int.Ed.2012,51,8644–8647.
20.XiaoXiao,XiaohuaLiu,ShunxiDong,YunfeiCai,LiliLin,XiaomingFeng*,AsymmetricSynthesisof2,3-Dihydroquinolin-4-oneDerivativesCatalyzedbyaChiralBisguanidiumSalt,Chem.Eur.J.2012,18,15922–15926.
21.MingshengXie,XiaohuaLiu,XiaoxiaWu,YunfeiCai,LiliLin,XiaomingFeng*,CatalyticAsymmetric[8+2]Cycloaddition:SynthesisofCycloheptatriene-FusedPyrroleDerivatives,Angew.Chem.Int.Ed.2013,52,5604-5607.
22.YonghaiHui,JunJiang,WentaoWang,WeiliangChen,YunfeiCai,LiliLin,XiaohuaLiu,XiaomingFeng*,HighlyEnantioselectiveConjugateAdditionofThioglycolatetoChalconesCatalyzedbyLanthanum:LowCatalystLoadingandRemarkableChiralAmplification,Angew.Chem.Int.Ed.2010,49,4290-4293.
23.WeiliangChen,YonghaiHui,XinZhou,JunJiang,YunfeiCai,XiaohuaLiu,LiliLin,XiaomingFeng*,ChiralN,N'-Dioxide-Yb(III)ComplexesCatalyzedEnantioselectiveHydrophosphony-lationofAldehydes,TetrahedronLett.2010,51,4175–4178.
24.YonghaiHui,WeiliangChen,WentaoWang,JunJiang,YunfeiCai,LiliLin,XiaohuaLiu,XiaomingFeng*,HighlyEnantioselectiveZinc-CatalyzedFriedel–CraftsAlkylationofIndoleswithEthylTrifluoropyruvate,Adv.Syn.Cat. 2011,18,3174-3178.
25.ZhenWang,ZuliangZhang,QianYao,XiaohuaLiu,YunfeiCai,LiliLin,XiaomingFeng*,HighlyStereoselectiveConjugateAdditionandα-AlkynylationReactionwithElectron-DeficientAlkynesCatalyzedbyChiralScandium(III)Complexes,Chem.Eur.J.2013,19,8591–8596.
