董曉燕，天津大學化工學院教授，博導。
學術兼職,教育科研,研究方向,講授課程,科研項目,論著專利,
學術兼職
美國化學工程師協會（AIChE）高級會員；美國化學學會（ACS）會員
教育科研
研究方向
1， 生物大分子的結構與功能、蛋白質摺疊
2， 生物大分子的分離純化
2， 生物大分子的分離純化
講授課程
1， 生物化學
2， 生物化學實驗
3， 分子生物學
2， 生物化學實驗
3， 分子生物學
科研項目
共獲基金10餘項，目前承擔：
1， 天津市套用基礎及前沿技術研究計畫重點項目(13JCZDJC27700 ) 基因重組蛋白質藥物高效復性技術研究 2013.4-2016.3 (20萬)
2， 國家自然科學基金（21376172）澱粉質β多肽聚集的親和納米抑制劑的設計和作用機理研究 2014.1-2017.12 (80萬)
1， 天津市套用基礎及前沿技術研究計畫重點項目(13JCZDJC27700 ) 基因重組蛋白質藥物高效復性技術研究 2013.4-2016.3 (20萬)
2， 國家自然科學基金（21376172）澱粉質β多肽聚集的親和納米抑制劑的設計和作用機理研究 2014.1-2017.12 (80萬)
論著專利
出版教材：
1，《生物化學》 “十一五”國家級規劃教材，高教出版社（2010）
2，《生物化學實驗》第二版，“十一五”規劃教材，化工出版社（2008）
共發表論文120餘篇；近五年30餘篇（SCI收錄25篇）；代表性文章：
1 Hu Liu, Wen-Jie Du, Xiao-Yan Dong, Yan Sun: Integrative refolding and purification of histidine-tagged protein bylike-charge facilitated refolding and metal-chelate affinity adsorption. Journal of Chromatography A, 2014,1344: 59-65
2 Ming-Tao Gao, Xiao-Yan Dong, Yan Sun*: Interactions Between L-Arginine/L-Arginine Derivatives and Lysozyme and Implications to Their Inhibition Effects on Protein Aggregation . Biotechnol. Prog., 2013, 29(5) 1316-1324
3 Na Zhang, Fu-Feng Liu*, Xiao-Yan Dong, Yan Sun*: Counteraction of trehalose on urea-induced protein unfolding:Thermodynamic and kinetic studies. Biochemical Engineering Journal, 2013, 79: 120-128
4 Fu-Feng Liu, Bo Huang, Xiao-Yan Dong, Yan Sun: Molecular Basis for the Dissociation Dynamics of Protein A-Immunoglobulin G1 Complex. PLOS ONE, 2013, June, 8 | Issue 6 | e66935
5 C.-Y. Yang, Ming Li, X.-Y. Dong, Y. Sun*: A double-modification strategy for enhancing charge density of mono-sized beads for facilitated refolding of like-charged protein. Journal of Chromatography A, 2013, 1299: 85-93.
6 Guang-Jie Han, Xiao-Yan Dong, Yan Sun*: Purification effect of artificial chaperone in the refolding of recombinant ribonuclease A from inclusion bodies. Biochemical Engineering Journal, 2013, 77: 15-19
7 Hu Liu, Xiao-Yan Dong, Yan Sun*: Peptide disulfide RKCGCFF facilitates oxidative protein refolding by mimicking protein disulfide isomerase. Biochemical Engineering Journal, 2013 ,79: 29- 32
8 S.-H. Wang, F.-F. Liu, X.-Y. Dong, Y. Sun*: Calorimetric and spectroscopic studies of the interactions between insulin and (-)-epigallocatechin-3-gallate. Biochemical Engineering Journal, 2012, 62 (1): 70-78
9 S.-H. Wang, X.-Y. Dong, Y. Sun*: Thermodynamic analysis of the molecular interactions between amyloid β-peptide fragments and (-)-epigallocatechin-3-gallate. The Journal of Physical Chemistry B, 2012, 116 (20): 5803–5809.
10 S.-H. Wang, X.-Y. Dong, Y. Sun*: Effect of (-)-epigallocatechin-3-gallate on human insulin fibrillation/aggregation kinetics. Biochemical Engineering Journal, 2012, 63 (1): 38-49.
獲得專利10餘項，其中國際專利1項
1 孫彥，譚國民，史清洪，董曉燕，白姝：橫向電場提高離子交換吸附劑動態吸附容量的方法，中國發明專利，ZL 200510014696.4，授權公告日: 2007年6月13日（授權公告號：CN1320939C）
2 11孫彥，孫國勇，董曉燕，白姝，史清洪：以碳酸鈣微粒懸浮液製備超大孔型剛性高分子介質的方法，中國發明專利，ZL 200510013278.3，授權公告日: 2008年2月13日（授權公告號：CN100368075C）
3 12 孫彥，王冬梅，史清洪，董曉燕，白姝：超大孔纖維素微球蛋白質吸附介質的製備方法，中國發明專利，200710056590.X 授權公告日: 年 月 日（授權公告號：ZL 200710056590.X）
4 13 徐 亮，孫 彥，史清洪，白 姝，董曉燕：聚乙烯醇塗層毛細管的製備方法及套用，中國發明專利， 200910067986.3，.授權公告日: 2011年10月27 日（授權公告號：200910067986.3）
5 Y. Sun, G.-Z. Wang, Q-H Shi, X.-Y. Dong: Method of Protein Refolding with IonExchange Resins and the Application of the Same. 公開號（Pub No.）: US2013/0060007 A1（2013-3-7）
1，《生物化學》 “十一五”國家級規劃教材，高教出版社（2010）
2，《生物化學實驗》第二版，“十一五”規劃教材，化工出版社（2008）
共發表論文120餘篇；近五年30餘篇（SCI收錄25篇）；代表性文章：
1 Hu Liu, Wen-Jie Du, Xiao-Yan Dong, Yan Sun: Integrative refolding and purification of histidine-tagged protein bylike-charge facilitated refolding and metal-chelate affinity adsorption. Journal of Chromatography A, 2014,1344: 59-65
2 Ming-Tao Gao, Xiao-Yan Dong, Yan Sun*: Interactions Between L-Arginine/L-Arginine Derivatives and Lysozyme and Implications to Their Inhibition Effects on Protein Aggregation . Biotechnol. Prog., 2013, 29(5) 1316-1324
3 Na Zhang, Fu-Feng Liu*, Xiao-Yan Dong, Yan Sun*: Counteraction of trehalose on urea-induced protein unfolding:Thermodynamic and kinetic studies. Biochemical Engineering Journal, 2013, 79: 120-128
4 Fu-Feng Liu, Bo Huang, Xiao-Yan Dong, Yan Sun: Molecular Basis for the Dissociation Dynamics of Protein A-Immunoglobulin G1 Complex. PLOS ONE, 2013, June, 8 | Issue 6 | e66935
5 C.-Y. Yang, Ming Li, X.-Y. Dong, Y. Sun*: A double-modification strategy for enhancing charge density of mono-sized beads for facilitated refolding of like-charged protein. Journal of Chromatography A, 2013, 1299: 85-93.
6 Guang-Jie Han, Xiao-Yan Dong, Yan Sun*: Purification effect of artificial chaperone in the refolding of recombinant ribonuclease A from inclusion bodies. Biochemical Engineering Journal, 2013, 77: 15-19
7 Hu Liu, Xiao-Yan Dong, Yan Sun*: Peptide disulfide RKCGCFF facilitates oxidative protein refolding by mimicking protein disulfide isomerase. Biochemical Engineering Journal, 2013 ,79: 29- 32
8 S.-H. Wang, F.-F. Liu, X.-Y. Dong, Y. Sun*: Calorimetric and spectroscopic studies of the interactions between insulin and (-)-epigallocatechin-3-gallate. Biochemical Engineering Journal, 2012, 62 (1): 70-78
9 S.-H. Wang, X.-Y. Dong, Y. Sun*: Thermodynamic analysis of the molecular interactions between amyloid β-peptide fragments and (-)-epigallocatechin-3-gallate. The Journal of Physical Chemistry B, 2012, 116 (20): 5803–5809.
10 S.-H. Wang, X.-Y. Dong, Y. Sun*: Effect of (-)-epigallocatechin-3-gallate on human insulin fibrillation/aggregation kinetics. Biochemical Engineering Journal, 2012, 63 (1): 38-49.
獲得專利10餘項，其中國際專利1項
1 孫彥，譚國民，史清洪，董曉燕，白姝：橫向電場提高離子交換吸附劑動態吸附容量的方法，中國發明專利，ZL 200510014696.4，授權公告日: 2007年6月13日（授權公告號：CN1320939C）
2 11孫彥，孫國勇，董曉燕，白姝，史清洪：以碳酸鈣微粒懸浮液製備超大孔型剛性高分子介質的方法，中國發明專利，ZL 200510013278.3，授權公告日: 2008年2月13日（授權公告號：CN100368075C）
3 12 孫彥，王冬梅，史清洪，董曉燕，白姝：超大孔纖維素微球蛋白質吸附介質的製備方法，中國發明專利，200710056590.X 授權公告日: 年 月 日（授權公告號：ZL 200710056590.X）
4 13 徐 亮，孫 彥，史清洪，白 姝，董曉燕：聚乙烯醇塗層毛細管的製備方法及套用，中國發明專利， 200910067986.3，.授權公告日: 2011年10月27 日（授權公告號：200910067986.3）
5 Y. Sun, G.-Z. Wang, Q-H Shi, X.-Y. Dong: Method of Protein Refolding with IonExchange Resins and the Application of the Same. 公開號（Pub No.）: US2013/0060007 A1（2013-3-7）
