胡益民 博士，二級教授，博士生導師，安徽省學術與技術帶頭人。2003年畢業於南京大學獲博士學位。2004年在美國Bowling Green State University從事博士後研究。發表專利及學術性研究論文120餘篇，其中SCI論文51篇，包括《Angew. Chem. Int. Ed.》、《Org. Lett.》、《Chem. Commun.》、《Adv. Synth. Catal.》 、《Chem. Eur. J.》等國際著名期刊。參加國際重要學術會議作邀請報告4次，成功申報了國家自然科學基金面上項目6項，獲得2010年度 “Thieme Chemistry Journals Award”國際獎。
研究方向,主持項目,代表性成果,會議論文,專 利,
研究方向
1. 芳炔HDDA的串聯環化反應
2. 金屬催化芳香雜環碳氫鍵活化
3. 綠色天然有機化學
主持項目
1.“多烯炔去氫芳構化構築複雜分子骨架的Domino反應研究”，國家自然科學基金，項目號：22071001，63萬，起止年月：2021.01–2024.12，項目負責人。
2. “多官能化複雜芳香功能化合物簡潔合成方法學研究”，國家自然科學基金，項目號：21572002，65萬，起止年月：2016.01–2019.12，項目負責人。
3. “過渡金屬催化的烯丙基化及多重烯炔連續Domino反應構建幾種環狀複雜體系化合物研究”，國家自然科學基金，項目號：21272005，80萬，起止年月：2013.01–2016.12，項目負責人。
4. “Podophyllotoxin和Conidendrin骨架及其衍生物的高效合成方法研究”，國家自然科學基金，項目號：21072003，36.0萬，2011–2013年,項目負責人。
5. “芳香雜環C-H鍵活化構築多環有機物的Domino反應研究”，國家自然科學基金，項目號：20872002，35.0萬，2009–2011年，項目負責人。
6. “鈀、銠、鎳催化活性丙烯醯基在離子液體中的選擇性成環偶聯反應研究”，國家自然科學基金，項目號：20572001，16.0萬(含學校配套經費)，2006–2007年，項目負責人。
7. 安徽省高等學校“十五”優秀人才計畫學科帶頭人基金，3.2萬，2005–2008年，項目負責人
代表性成果
1. "Fully Substituted Conjugate Benzofuran Core: Multiyne Cascade Coupling and Oxidation of Cyclopropenon", Liangliang Yao, Qiong Hu*, Li Bao, Wenjing Zhu, and Yimin Hu*, Org. Lett. 2021, 23, 4971-4975.
2. "Access to Benzoxazepines and Fully Substituted Indoles via HDDA Coupling", Xiaojie Zheng, Baohua Liu, Feihu Yang, Qiong Hu, Liangliang Yao, and Yimin Hu*, Org. Lett. 2020, 22, 956-959.
3. "Phenanthrenes/dihydrophenanthrenes: the selectivity controlled by different benzynes and allenes", Liangliang Yao, Bo Fang, Qiong Hu, Yu Lei, Li Bao and Yimin Hu*, Chem. Commun. 2020, 56, 15185-15188.
4. "C–O/C–S difunctionalized benzene derivatives via multicomponent coupling of tetraynes", Liangliang Yao, Qiong Hu, Yu Lei, Li Bao and Yimin Hu*, Org. Chem. Front. 2020, 7, 3633-3637.
5. "One-Step Synthesis of the Benzocyclo[penta- to octa-]isoindole Core", Yimin Hu*, Chenli Yu, Dong Ren, Qiong Hu, Lidong Zhang, Dong Cheng, Angew. Chem. Int. Ed. 2009, 48, 5448-5451.
6. "Direct methylation and carbonylation of in situ generated arynes via HDDA-Wittig coupling", Baohua Liu,Chunyan Mao,Qiong Hu,Liangliang Yao,Yimin Hu*, Org. Chem. Front. 2019, 6, 2788-2791.
7. "Versatile Dibenzothio[seleno]phenes via Hexadehydro-Diels–Alder Domino Cyclization", Baohua Liu, Qiong Hu, Yinshan Wen, Bo Fang, Xiaoliang Xu, Yimin Hu*, Front. Chem. 2019, 374.
8. "Fused Multifunctionalized Dibenzoselenophenes from Tetraynes", Yimin Hu*, Jie Ma, Lidong Li, Qiong Hu, Shuang Lv, Baohua Liu, Shaowu Wang*, Chem. Commun. 2017, 53, 1542-1545.
9. "Direct Access to Fused Salicylaldehydes and Salicylketones from Tetraynes", Yimin Hu*, Yadong Hu, Qiong Hu, Jie Ma, Shuang Lv, Baohua Liu, Shaowu Wang*, Chem. Eur. J. 2017, 23, 4605-4072.
10. "Fused Multifunctionalized Chromenes from Tetraynes and α,β-Unsaturated Aldehydes", Xiangzhen Meng, Shuang Lv, Dong Cheng, Qiong Hu, Jie Ma, Baohua Liu, Yimin Hu*, Chem. Eur. J. 2017, 23, 6264-6271.
11. "Fused Multifunctionalized Isoindole-1,3-diones via the Coupled Oxidation of Imidazoles and Tetraynes", Qiong Hu, Lidong Li, Fei Yin, Hao Zhang, Yadong Hu, Baohua Liu and Yimin Hu*, RSC Adv. 2017, 7, 49810-49816.
12. "Synthesis of a Type of Bridged Heterocycles via Tetraynes", Xiangzhen Meng, Dong Cheng*, Shuang Lv, Jie Ma, Yimin Hu*, Heterocycles 2017, 94, 2111-2124.
13. "Convenient One-Step Construction of Yne-Functionalized Aryl Halides through Domino Cyclization from Tetraynes", Hao Zhang, Qiong Hu, Lidong Li, Yimin Hu*, Pingping Zhou, Xiaorong Zhang, Haifeng Xie, Shaowu Wang*, Chem. Commun. 2014, 25, 3335-3337.
14. "One-Step Synthesis of Diazaspiro[4.5]decane Scaffolds with Exocyclic Double Bonds", Lidong Li, Qiong Hu, Pingping Zhou, Haifeng Xie, Xiaorong Zhang, Hao Zhang, Yadong Hu, Fei Yin, Yimin Hu*, Org. Biomol. Chem. 2014, 12, 5356-5359.
15. "Domino Access to Yne-functionalized Benzoisoindole from Triynes", Lidong Li, Qiong Hu, Pingping Zhou, Haifeng Xie, Xiaorong Zhang, Hao Zhang, Hua Wang, Yimin Hu*, Synthesis 2014, 46, 1547-1554.
16. "Fused Benzo[b]fluorenols: Palladium-Catalyzed Intramolecular Dehydroaromatization and Carbonyl Reduction", Quansheng Zhao, Qiong Hu, Lei Wen, Min Wu, Yimin Hu*, Adv. Synth. Catal. 2012, 354, 2113-2116.
17. "Synthesis of highly substituted dihydropyrrolophenanthridine derivatives by tandem reaction", Yimin Hu*, Tao Zhu, Xiaolong Mu, Quansheng Zhao, Tao Yu, Lei Wen, Yulong Zhang, MinWu, Hao Zhang, Tetrahedron 2012, 68, 311-318.
18. "Fused Phenanthridines: Domino Cyclization of 1,6-Diynes with Bromo(iso)quinoline", Yimin Hu*, Yongjie Sun, Jiping Hu, Tao Zhu, Tao Yu, Quansheng Zhao, Chem. Asian J. 2011, 6, 797-800.
19. "Construction of 3-Allyliodene-4-vinyltetrahydrofurans and 3-Allylidene-4-vinylpyrrolidines Via Sequential Domino Allylation/Olefination of CC Triple Bonds", Tuanjie Meng, Yimin Hu*, Quansheng Zhao, Tao Yu, and Shaowu Wang*, Tetrahedron 2011, 67, 8710-8716.
20. "Efficient Activation of Aromatic C-H Bonds for Fused Polyaromatic Hydrocarbon Construction", Yimin Hu*, Hao Yao, Yongjie Sun, Jing Wan, Xiangang Lin, Tao Zhu, Chem. Eur. J. 2010, 16, 7635-7641.
21. "Efficient Construction of Tri- and Tetracyclic Heterocycles from Linear 1,6-Dienes by a Domino Reaction", Yimin Hu*, Fengfa Song, Fenghua Wu, Dong Cheng, and Shaowu Wang*, Chem. Eur. J. 2008, 14, 3110-3117.
22. "Rapid construction of five contiguous stereocenters in a multi-cascade reaction", Yimin Hu*, Ying Ouyang, Yuan Qu, Qiong Hu and Hao Yao, Chem. Commun. 2009, 4575-4577.
23. "Tuned C-H Functionalization to Construct the Skeleton of Aza-Podophyllotoxin/Aza-Conidendrin via Domino Cyclization", Yimin Hu*, Yuan Qu, Fenghua Wu, Jinghan Gui, Yun Wei, Qiong Hu and Shaowu Wang*, Chem. Asian. J. 2010, 5, 309-314.
24. "Efficient Construction of Five-membered Aromatic and Nonaromatic Heterocycles from 1,6-Enynes by a Palladium-Catalyzed Domino Coupling/Cycloisomerization Process", Tuanjie Meng, Yimin Hu*, and Shaowu Wang*, J. Org. Chem. 2010, 75, 582-588.
25. "Palladium-Catalyzed C-C Coupling/C-H Activation: Formation of Isoindolinone-Fused Heterocyclic Compounds", Yimin Hu*, Dong Ren, Lidong Zhang, Xiangang Lin, Jing Wan, Eur. J. Org. Chem. 2010, 4454-4459.
26. "Coupling/Cyclization of 1,6-Enynes with Aryl Halides: an Efficient and General Route for the Synthesis of Functionalized Hexahydroindole and Hexahydrobenzofuran Derivatives", Tuanjie Meng, Yimin Hu*, Yongjie Sun, Tao Zhu, and Shaowu Wang*, Tetrahedron 2010, 8648-8653.
27. "A Convenient Domino Synthesis of 4,9-Diphenyl-2,3-dihydro-1H-benzo[f]iso-indole Derivatives", Yimin Hu*, Xiangang Lin, Tao Zhu, Jing Wan, Yongjie Sun, Quansheng Zhao, Tao Yu, Synthesis 2010, 3467-3473.
28. "Palladium-Catalyzed Cyclization of Benzyl Halides with Diethyl Diallylmalonate", \ Yimin Hu, Jie Zhou, Hongzhen Lian, Chengjian Zhu, Yi Pan*, Synthesis （Issue 8, 1177-1180, 2003）.
29. “Palladium-catalyzed cascade reaction of N-allyl-N-（2-butenyl）-p–toluenesulfon amide with benzyl halides”, Yimin Hu, Jie Zhou, Xiangtian Long, Jianlin Han, Chenjian Zhu, Yi Pan, Tetrahedron Lett. 2003, 44, 5009-5010.
30. "Palladium-catalyzed cascade reaction of N, N-diallylbenzoylamide with benzyl halides", Yimin Hu, Yu Zhang, Jianlin Han, Chengjian Zhu, Yi Pan*, Chin. Chem. Lett. 2003, 14, 771-772.
31. "Synthesis and Disproportionation of Mixed Ligand Indium Organometallics Involving Ethyl and β -Diketonate Chelate Ligands", Yimin Hu, Xiaohua Huang, Zhongwen Ye*, Xiuran Wang, Jiashan Gu, Chinese J. Chem. 2001, 19, 109-112.
會議論文
1. "Fused multifunctionalized dibenzoselenophenes from tetraynes", Baohua Liu and Yimin Hu*, "4th European Chemistry Congress" (Invited Oral Lecture), (May 11-13, 2017, Barcelona, Spain, 2017).
2. "ONSTRUCTION OF CONDENSED NUCLEUS BY PALLADIUM-CATALYZED DOMINO CYCLIZATION", Lidong Li and Yimin Hu*, The Collaborative Conference on Organic Synthesis (CCOS)Graduate University of Science and Technology (GUST) (Invited Oral Lecture), (March 13-17, Hanoi, Vietnam, 2017)
3. "Efficient Construction of Fused Heterocycles by Palladium-Catalyzed C-H Activation Domino Reaction″, Qiong Hu, Dong Ren, Lidong Zhang, Tao Zhu, Yongjie Sun and Yimin Hu*, The 2010 International Conference on Pure and Applied Chemistry (Oral Presentation), (July 25-30, Mauritius, 2010).
4. "Disproportionation of Indium Organometallics Involving Ethyl and Chelate Ligands″, Yimin Hu, Xiaohua Huang, Zhongwen Ye*, Xiuran Wang, Baohui Du, The 19th IUPAC International Conference on Organometallic Chemistry, (July 23-28, Shanghai China, PS056, 2000).
5. “構築苯並環化異吲哚骨架的Domino反應研究”, 萬靜, 林先剛, 姚浩, 胡益民*, 第六屆全國有機化學會議, P775, 中國, 西安, 2009年8月17-20日.
6. “形成吲哚化合物及其衍生物反應中的鈀氧化催化研究”，孟團結, 胡益民*, 朱濤, 孫永傑, 王紹武*, 第六屆全國有機化學會議, P774, 中國, 西安, 2009年8月17-20日.
7.“在離子液體中進行的電化學支持的Heck反應”, 曲媛, 盧嘉, 桂敬漢, 胡益民*, 褚道葆*, 第五屆全國有機化學會議, P330, 中國, 鄭州, 2007年8月18-22日.
8. “鎳催化的電化學偶聯反應”, 盧嘉, 曲媛, 桂敬漢, 褚道葆*, 胡益民*, 第五屆全國有機化學會議, P331, 中國, 鄭州, 2007年8月18-22日.
9. “微波在鈀催化下的偶聯成環反應中的套用”, 胡益民*, 張霞, 曲媛, 吳鳳華, 程東, 第四屆全國有機化學會議(口頭報告), P96, 中國, 昆明, 2005年8月8-11日.
10. “二烯丙基丙二酸二乙酯與苄基鹵化物的鈀催化下的成環反應”, 胡益民, 潘毅*, 第二屆全國有機化學會議(口頭報告), 中國, 杭州, 2001年8月5-8日.
11. “有機銦衍生物的合成研究”, 胡益民, 周虹屏, 葉鐘文, 王修然, 第十屆全國金屬有機化學會議, P218, 中國, 長沙, 1998年10月7-11日.
12. “三乙基銦的合成研究”, 胡益民, 黃小華, 顧家山, 王修然, 葉鐘文, 第十屆全國金屬有機化學會議, P219, 中國, 長沙, 1998年10月7-11日.
專 利
1. 一種帶環外雙鍵二氮雜螺[4.5]癸烷衍生物及其合成方法, 201410293047.1, 授權日期: 2017.1.4
2.一種芴酮衍生物及其製備以及合成芴酮的氧化還原方法, 201410725048.9, 授權日期: 2017.1.4
3. 一種肉桂酸酯類衍生物及其製備方法, 201410728360.3, 授權日期: 2017.1.4
4. 一種安息香肟衍生物及其製備方法, 201410728358.6, 授權日期: 2017.1.11
5. 一種芳鹵衍生物及其合成方法, 201410293039.7, 授權日期: 2017.4.12
6. 一種1,5-二羰基衍生物及其製備方法, 201510896115.8, 授權日期: 2017.6.16
7. 一種二苯碲醚衍生物及其製備方法, 201610070522.8, 授權日期: 2017.10.25。
