胡燚， 男，1975年生，中共黨員，理學博士，現任南京大學工業生物技術創新中心教授、碩士生導師。
基本介紹
- 中文名：胡燚
- 國籍：中國
- 出生日期：1975年
- 畢業院校：浙江大學
- 學位/學歷：博士
- 職務：碩士生導師
人物經歷,研究方向,主講課程,科研成果,
人物經歷
2005年3月，獲得浙江大學有機化學專業博士學位，2012-2013年在美國The Scripps Research Institute 做訪問學者研究工作。
研究方向
主要研究方向為生物催化、化學催化、生物-化學組合合成技術在生物煉製、醫藥及其中間體、精細化學品等綠色合成中的套用研究。
主講課程
《生物煉製》《高等有機化學》與《藥物合成反應》。
科研成果
- 科研項目
作為項目負責人完成了材料化學工程國家重點實驗室重點課題—生物乙醇脫水制乙烯高性能分子篩催化劑複合改性和反應器設計研究（ZK200815），江蘇省自然科學基金—生物乙醇脫水制乙烯高性能分子篩催化劑及其反應器研究（BK2009494），國家自然科學基金青年基金項目—功能化離子液體修飾介孔材料在酶固定化中的套用研究（20906049），中石化科技開發項目—熔鹽循環等溫固定床數值模擬及中試實驗研究（L411003）。目前作為子課題負責人承擔國家863計畫重大項目—手性醇的不對稱合成技術（2011AA02A209，2011-2015）、國家發改委高技術產業化項目—酶法生產百噸級左旋帕羅醇示範工程等項目的研究工作。共發表學術論文80餘篇，獲授權發明專利10餘項。
- 近年來部分論文
(1) Yi Hu, Jiao Yang, Ru Jia, Yan Ding. Shuang Li, He Huang*. Chemical modification with functionalized ionic liquids: a novel method to improve the enzymatic properties of Candida rugosa lipase. Bioprocess. Biosyst. Eng., DOI: 10.1007/s00449-014-1134-4.
(2) Ru Jia, Yi Hu*, He Huang*. Improving the catalytic performance of Porcine pancreatic lipase in the presence of [MMIm][MeSO4] with the modification of functional ionic liquids. Process Biochem., DOI: org/10.1016/j.procbio.2014.01.
(3) Weiming Liu, Jixing Luo, Xiaojian Zhuang, Wenhe Shen, Yang Zhang, Shuang Li , Yi Hu*, He Huang*. Efficient preparation of enantiopure l-tert-leucine through immobilized penicillin G acylase catalyzed kinetic resolution in aqueous medium. Biochem. Eng. J., 2014, 83, 116.
(4) Bin Zou, Yi Hu*, Fengjie Cui, Ling Jiang, Dinghua Yu, He Huang*. Effect of surface modification of low cost mesoporous SiO2 carriers on the properties of immobilized lipase. J. Colloid. Interf. Sci., 2014, 417, 210.
(5) Ru Jia, Yi Hu*, Ling Jiang, He Huang*. Chemical modification for improving activity and stability of lipase B from Candida antarctica with imidazolium-functional ionic liquids. Org. Biomol. Chem., 2013, 11, 7192.
(6) Ru Jia, Yi Hu, Luo Liu, Ling Jiang, Bin Zou, He Huang*. Enhancing catalytic performance of Porcine pancreatic lipase by covalent modification using functional ionic liquids. ACS Catal., 2013, 3, 1976.
(7) Bin Zou, Yi Hu, Ling Jiang, Jiao Yang, Ru Jia, He Huang*. Mesoporous material SBA-15 modified by amino acid ionic liquid to immobilize lipase via ionic bonding and cross-linking method. Ind. Eng. Chem. Res., 2013, 52, 2844.
(8) Jiao Yang, Yi Hu, Ling Jiang, Bin Zou, Ru Jia, He Huang*. Enhancing the catalytic properties of porcine pancreatic lipase by immobilization on SBA-15 modified by functionalized ionic liquid. Biochem. Eng. J., 2013, 70, 46.
(9) Xiangjun Jiang, Yi Hu, Lin Jiang, Bin Zou, He Huang*. Optimization of enzymatic synthesis of L-ascorbyl palmitate by solvent engineering and statistical experimental designs. Biotechnol. Bioproc. Eng., 2013, 18, 350.
(10) Xiangjun Jiang, Yi Hu, Lin Jiang, Jihong Gong, He Huang*. Synthesis of vitamin E succinate using Candida rugosa lipase in organic medium. Chem. Res. Chin. Univ., 2013, 29, 223.
(11) Yi Hu, Xiangjun Jiang, Suwen Wu, Ling Jian, He Huang*.Synthesis of vitamin E succinate by interfacial activated Candida rugosa lipase encapsulated in sol-gel materials. Chin. J. Catal., 2013, 34, 1608.
(12) Xiaochen Wang, Yi Hu, Samuel Bonacorsi, Yang Hong, Richard Burrell, Jinquan Yu*. Pd(II)-Catalyzed C−H iodination using molecular I2 as the sole oxidant. J. Am. Chem. Soc., 2013, 135, 10326.
(13) 胡燚, 楊姣, 唐蘇蘇, 初旭明, 鄒彬, 黃和*. 氨基功能化離子液體修飾的SBA-15共價固定Burkholderia cepacia脂肪酶. 高等學校化學學報, 2013, 34, 1195.
(14) 丁雁, 黃和, 胡燚*. 脂肪酶催化C-C鍵形成反應研究進展, 有機化學, Chin. J. Org. Chem. 2013, 33, 905.
(15) Yi Hu, Susu Tang, Ling Jiang, Bin Zou, Jiao Yang, He Huang*. Immobilization of Burkholderia cepacia lipase on functionalized ionic liquids modified mesoporous silica SBA-15. Process Biochem., 2012, 47, 2291.
(16) Susu Tang, Yi Hu*, Dinghua Yu, Bin Zou, Ling Jiang, Immobilization of Burkholderia Cepacia lipase on functionalized ionic liquids modified mesoporous silica SBA-15. Chin. J. Catal., 2012, 33, 1565.
(17) Weiming Liu, Yi Hu, Ling Jiang, Bin Zou, He Huang*, Synthesis of methyl (R)-3-(4-fluorophenyl)glutarate via enzymatic desymmetrization of a prochiral diester. Process Biochem., 2012, 47,1037.
(18) Bin Zou, Yi Hu*, Dinghua Yu, Ling Jiang, Weiming Liu, Ping Song, Functional ionic liquid modified mesoporous silica SBA-15: a novel, designable and efficient carrier for porcine pancreas lipase. Colloids and Surface B: Biointerfaces, 2011, 93.
(19) Xinjiang Huang, Yi Hu*, Dinghua Yu, Yuwang Han, Effect of fusel on dehydration reaction of ethanol to ethylene catalyzed by La/HZSM-5. Chem. Ind. Eng. Soc. Chin., 2011, 62, 97.
(20) Bin Zou, Yi Hu, Dinghua Yu, Jiaojiao Xia, Susu Tang, Weiming Liu, He Huang*，Immobilization of porcine pancreatic lipase onto ionic liquid modified mesoporous silica SBA-15. Biochem. Eng. J., 2010, 53, 150.
(21) Yi Hu, Weiming Liu, Bin Zou, Susu Tang, He Huang*. Enzyme immobilization on mesoporous materials. Prog. Chem., 2010, 22, 1656.
(22) Yaochi Hu, Nina Zhan, Chang Dou, He Huang, Yuwang Han, Dinghua Yu，Yi Hu*. Selective dehydration of bio-ethanol to ethylene catalyzed by lanthanum-phosphorous-modified HZSM-5: influence of the fusel. Biotechnol. J., 2010, 11, 1186.
(23) Nina Zhan, Yi Hu, Heng Li, Dinghua Yu, Yuwang Han, He Huang*. Lanthanum-phosphorous modified HZSM-5 catalysts in dehydration of ethanolto ethylene: a comparative analysis. Catal. Commun., 2010, 11, 633.
(24) Xinjiang Huang, Kaimei Fu, Yaochi Hu, Bin zou, Yi Hu*, Alkylation of benzene with 1-butylene over βzeolite modified by Fe or La. Chem. Ind. Eng. Soc. Chin., 2009, 60, 2497.
(25) Yi Hu, Tao Xie, Kaimei Fu, Hui Kang, Ping Wei, He Huang*, A convenient synthesis of 5-arylidenethiazolidine-2,4-diones catalyzed by alkaline ionic liquid. Heterocycles, 2009, 78, 757.
(26)Yi Hu, Hui Kang, Biwen Zeng, Ping Wei, He Huang*. Facile synthesis of 3-arylidene-1,3-dihydroindol-2-ones catalyzed by brØnsted acidic ionic liquids. J. Chem. Res., 2008, 642.
(27) Yi Hu*, Heng Li, He Huang, Ping Wei, Advance of liquid-phase organic synthesis using functional ionic liquids as supports. Chin. J. Org. Chem., 2007, 27, 1188.
(28)Yi Hu*, Ping Wei, Pingkai Ouyang, ZhenChu Chen, Organic synthesis in ionic liquids: condensation of 3-methyl-1-phenyl-5-pyrazolone with carbonyl compounds catalyzed by ethylenediammonium diacetate (EDDA). Chin. Chem. Lett., 2006, 17, 299.
(29) Yi Hu*, Ping Wei, He Huang and Pingkai Ouyang, Synthesis of 2-aminothiophenes on ionic liquids-phase-support using the Gewald reaction. Synth.Commun., 2006, 36, 1543.
(30) Yi Hu*, Ping Wei, He Huang, Shiqing Han and Pingkai Ouyang, Microwave-assisted Gewald synthesis of 2-aminothiophenes using functional ionic liquid as soluble support. Heterocycles, 2006, 68, 375.
