翟萬銀

翟萬銀，男， 博士，副研究員，2002年6月畢業於華東師範大學生命科學院生物化學與分子生物學專業，獲碩士學位。

基本介紹

• 中文名：翟萬銀
• 畢業院校：華東師範大學
• 主要成就：“複合天然交聯劑對動物心臟瓣膜交聯作用的研究”
• 職稱：副研究員

個人信息

翟萬銀，副研。

簡歷

2011年6月畢業於中國科學院上海灶炒探微系統與信息技術研究所微電子與固體電子專業，獲民遙永博士學位。2002年7月進入中國科學院上海矽酸鹽研究所生物材料與組織工程研究中心坑檔海危。主要研究方向（1）生物材料的生物相容性研究和（2）心血管組織工程研究。主持完成上海市自然基金項目“用豬主動脈瓣及人骨髓乾細嚷只多胞構建人心臟瓣膜”， 國家863項目“新型納米藥物載體靶向控釋技術及其細胞生朽漿判物學效應研究”子課題；作為主要完成人完成了國家自然基金項目“複合天然交聯劑對動物心臟瓣膜交聯作用的研究”、“天然交聯劑原花青素對動物心臟瓣膜交聯作用的研究”，目前承擔國家自然基金面趨棗上項目“多酚對瓣膜彈性蛋白的交聯及其在原位組織工程瓣膜支架製備中的套用研究”。

發表論文

1.Zhai W, Chang J, Lin K, Wang J, Zhao Q, Sun X. Crosslinking of decellularized porcine heart valve by procyanidins. Biomaterials

2. Zhai W, Chang J, Lu X. Procyanidins crosslinked heart valve matrix: Anti-calcification effect. Journal of Biomedical Materials Research Part B: Appl Biomater

3. Zhai W, Lu X, Chang J, Zhou Y, Zhang H. Quercetin crosslinked porcine heart valve matrix: mechanical property, stability, anti-calcification and cytocompatibility. Acta Biomaterialia

4. LüX, Zhai W (co-First author), Zhou Y, Zhou Y, Zhang H, Chang J. Crosslinking effect of Nordihydroguaiaretic acid (NDGA) on decellularized heart valve scaffold for tissue engineering, J. Mater Sci:Mater Med

5. Zhai W, Jia C, Zhao H, Xu Y. Procyanidins inhibit tumor angiogenesis by crosslinking extracellular matrix. Chin J Cancer Res

6. 翟萬銀，吳蕾，賈春平，邵建波，徐元森. 腫瘤微血管芯雅煉符霸片的製備及其在通透性檢測方面的套用. 功能材料與器件學報, 2011,.

7. 翟萬銀，周雙雯，賈春萍，徐元森. 藤黃酸抗腫瘤細胞生物學機制研究進展. 細胞生物學學報

8. Zhai W, Jia C, Lou X, Jin Q, Zhao J, Xu Y. Enhanced antitumor activity of Irinotecan combined with gambogic acid on NSCLC. 21st IUBMB and 12st FAOBMB International Congress of Biochemistry and Molecular Biology, August 2-7, 2009, Shanghai, China. Abstract

9. Zhai W, Lu H, Chen L, Lin X, Huang Y, Dai K, Naoki K, Chen G, Chang J. Akermanite, a silicate bioceramic, stimulates in vitro and in vivo angiogenesis. European Cell and Material Journal, Under review.

10. Zhai W, He C, Wu L, Zhou Y, Guo L, Chen Y, Chen H, Chang J. Degradation of hollow mesoporous silica nanoparticles (HMSN) in human umbilical vein endothelial cells. Naomedicine: Nanotechnology Biology Medicine, Under review.

11. Zhai W, Lu H, Chen L, Lin X, Huang Y, Dai K, Naoki K, Chen G, Chang J. Implications from comparative study on Si-containing ceramics and β-TCP: the key role of Si in in vitro cell proliferation, osteo-differentiation and angiogenesis. Biomaterials, Submitted.

12. Zhai W, Chang J. Procyanidins-crosslinked porcine heart valve matrix: mechanical characteristics, stability and biocompatibility. Oral

13. Zhai W, Chang J. Crosslinking-decellularized valvular ECM for bioprostheses using procyanidins. Chinese Biomaterials Congress, Chengdu, Oral

14. 何常亮, 翟萬銀(共通訊作者)，張紅霞, 常江，張紅峰，郭利民，陳航榕. 中空介孔矽球對血管內皮細胞的細胞毒性.華東師範大學學報(自然科學板)

15. Xie Y, Zhai W, Chen L, Chang J, Zheng X and Ding C. Preparation and in vitro evaluation of plasma-sprayed Mg2SiO4 coating on titanium alloy. Acta Biomaterialia

16. Zhang M, Zhai W, Lin K, Pan H, Lu W, Chang J. Synthesis, in-vitro hydroxyapatite forming ability, and cytocompatibility of strontium silicate powders. Journal of Biomedical Materials Research Part B (JBMR:B), Applied Biomaterials, Inpress.

17. Wu C, Chang J, Zhai W, Ni S, Wang J. Porous akermanite scaffolds for bone tissue engineering: Preparation, characterization, and in vitro studies. Journal of Biomedical Materials Research Part B: Applied Biomaterials

18. Zhao L, Chang J and Zhai W. Preparation and HL-7702 cell functionality of titania/chitosan composite scaffolds. J Mater Sci: Mater Med

19. Zhao W, Chang J, Zhai W. Self-setting properties and in vitro bioactivity of Ca3SiO5/CaSO4 1/2H2o composite cement. Journal of Biomedical Materials Research Part A

20. Wu C, Chang J, Zhai W and Ni S. A novel bioactive porous bredigite (Ca7MgSi4O16) scaffold with biomimetic apatite layer for bone tissue engineering.Journal of Materials Science: Materials in Medicine

21. Zhao L, Chang J, Zhai W. Experimental research of preparation and characterization of chitosan/TiO2 composite films. Journal of Tissue Engineering and Reconstructive Sugery,

22. Du RL, Chang J, Ni SY, Zhai W, Wang JY, Characterization and in vitro bioactivity of zinc-containing bioactive glasses and glass-ceramics, J Biomater Appl

23. Ni S, Chang J, Chou L, Zhai W. Comparison of osteoblast-like cell responses to calcium silicate and tricalcium phosphate ceramics in vitro. J Biomed Mater Res B

24. Xie Y, Zheng X, Ding C, Zhai W, Chang J, and Ji H. Preparation and Characterization of CaO-ZrO2-SiO2 Coating for Potential Application in Biomedicine. J Thermal Spray Technol

25. Zhao W, Chang J, Wang J, Zhai W and Wang Z. In vitro bioactivity of novel tricalcium silicate ceramics. Journal of Materials Science: Materials in Medicine

26. Wang KW, Zhu YJ, Chen XY, Zhai W, Wang Q, Chen F, Chang J and Duan Y-R. Flower-like hierarchically nanostructured hydroxyapatite hollow spheres: facile preparation and application in anticancer drug cellular delivery. Chemistry – An Asian Journal

27. Ning C, Ding D, Dai K, Zhai W and Chen L. The effect of Zr content on the microstructure, mechanical properties and cell attachment of Ti–35Nb–xZr alloys. Biomed. Mater

28. Chen F, Tang QL, Zhu YJ, Wang KW, Zhang ML, Zhai W, Chang J. Hydroxyapatite nanorods/poly(vinyl pyrolidone) composite nanofibers, arrays and three-dimensional fabrics: Electrospun preparation and transformation to hydroxyapatite nanostructures. Acta Biomaterialia

29. Wanyin Zhai, Kaili Lin, Jiang Chang. Study on crosslinking of porcine heart valve matrix using procyanidins. The 8th Annual Meeting of Tissue Engineering Society Internation

30. 翟萬銀，常 江，趙 強，徐德明.組織工程心臟瓣膜研究進展，國外醫學.生物醫學工程學

31. 翟萬銀,朱振勤,陳季武,王雲丹,趙子寅,胡天喜.雷震子護康膠囊製劑抗氧化和對DNA損傷保護作用研究，發光學報

32. 朱振勤,翟萬銀,陳季武,夏晶,傅蓓蓓,謝萍,胡天喜.葡萄籽提取物抗氧化及對DNA保護作用研究，華東師範大學學報

33. Zhu ZQ, Zhai WY, Chen JW, Xia J, Xie P. Effects of grape seed procyanidin scavenging free radicals and protecting cultured bovine aortic cells from oxidative damage. Acta biochemica et biophysica sinica

34. Lin KL, Zhai WY, Ni SY, Chang J, Zeng Y, Qian W, Study of the mechanical property and in vitro biocompatibility of CaSiO3 ceramics, Ceramics International

35. Wenyuan Zhao, Junying Wang, Wanyin Zhai, Zheng Wang, Jiang Chang. The self-setting properties and in vitro bioactivity of tricalcium silicate.Biomaterials

36. Wu CT, Chang J, Zhai WY, A novel hardystonite bioceramic: preparation and characteristics, Ceramics International

37. Gou Z, Chang J, Zhai W, Preparation and characterization of novel bioactive dicalcium silicate ceramics. J. Eur. Ceram. Soc

38. Zhao L, Chang J, Zhai W. Effect of dissolution and different crystallographic phasephases of TiO2 on hepatocyte response in vitro. Journal of Biomaterials Applications

39. Gou Z, Chang J, Zhai W, Wang JY, Study on the self-setting property and the in vitro bioactivity of b-Ca2SiO4, Journal of Biomedical Materials Research Part B (JBMR:B), Applied Biomaterials

40. Wu CT, Chang J, Wang JY, Ni SY, Zhai WY, Preparation and Characteristics of a Calcium Magnesium Silicate (Bredigite) Bioactive Ceramic. Biomaterials

專利

（1）常江，翟萬銀. 發明名稱“具有生物活性的人工生物瓣瓣膜的製備方法”.中國專利號

（2）常江，翟萬銀. 發明名稱“採用槲皮素交聯製備人工生物心臟瓣膜材料的方法”.中國專利申請號

（3）常江，翟萬銀. 發明名稱“一種可再細胞化的人工生物心臟瓣膜”.中國專利申請號

8. Zhai W, Jia C, Lou X, Jin Q, Zhao J, Xu Y. Enhanced antitumor activity of Irinotecan combined with gambogic acid on NSCLC. 21st IUBMB and 12st FAOBMB International Congress of Biochemistry and Molecular Biology, August 2-7, 2009, Shanghai, China. Abstract

9. Zhai W, Lu H, Chen L, Lin X, Huang Y, Dai K, Naoki K, Chen G, Chang J. Akermanite, a silicate bioceramic, stimulates in vitro and in vivo angiogenesis. European Cell and Material Journal, Under review.

10. Zhai W, He C, Wu L, Zhou Y, Guo L, Chen Y, Chen H, Chang J. Degradation of hollow mesoporous silica nanoparticles (HMSN) in human umbilical vein endothelial cells. Naomedicine: Nanotechnology Biology Medicine, Under review.

11. Zhai W, Lu H, Chen L, Lin X, Huang Y, Dai K, Naoki K, Chen G, Chang J. Implications from comparative study on Si-containing ceramics and β-TCP: the key role of Si in in vitro cell proliferation, osteo-differentiation and angiogenesis. Biomaterials, Submitted.

12. Zhai W, Chang J. Procyanidins-crosslinked porcine heart valve matrix: mechanical characteristics, stability and biocompatibility. Oral

13. Zhai W, Chang J. Crosslinking-decellularized valvular ECM for bioprostheses using procyanidins. Chinese Biomaterials Congress, Chengdu, Oral

14. 何常亮, 翟萬銀(共通訊作者)，張紅霞, 常江，張紅峰，郭利民，陳航榕. 中空介孔矽球對血管內皮細胞的細胞毒性.華東師範大學學報(自然科學板)

15. Xie Y, Zhai W, Chen L, Chang J, Zheng X and Ding C. Preparation and in vitro evaluation of plasma-sprayed Mg2SiO4 coating on titanium alloy. Acta Biomaterialia

16. Zhang M, Zhai W, Lin K, Pan H, Lu W, Chang J. Synthesis, in-vitro hydroxyapatite forming ability, and cytocompatibility of strontium silicate powders. Journal of Biomedical Materials Research Part B (JBMR:B), Applied Biomaterials, Inpress.

17. Wu C, Chang J, Zhai W, Ni S, Wang J. Porous akermanite scaffolds for bone tissue engineering: Preparation, characterization, and in vitro studies. Journal of Biomedical Materials Research Part B: Applied Biomaterials

18. Zhao L, Chang J and Zhai W. Preparation and HL-7702 cell functionality of titania/chitosan composite scaffolds. J Mater Sci: Mater Med

19. Zhao W, Chang J, Zhai W. Self-setting properties and in vitro bioactivity of Ca3SiO5/CaSO4 1/2H2o composite cement. Journal of Biomedical Materials Research Part A

20. Wu C, Chang J, Zhai W and Ni S. A novel bioactive porous bredigite (Ca7MgSi4O16) scaffold with biomimetic apatite layer for bone tissue engineering.Journal of Materials Science: Materials in Medicine

21. Zhao L, Chang J, Zhai W. Experimental research of preparation and characterization of chitosan/TiO2 composite films. Journal of Tissue Engineering and Reconstructive Sugery,

22. Du RL, Chang J, Ni SY, Zhai W, Wang JY, Characterization and in vitro bioactivity of zinc-containing bioactive glasses and glass-ceramics, J Biomater Appl

23. Ni S, Chang J, Chou L, Zhai W. Comparison of osteoblast-like cell responses to calcium silicate and tricalcium phosphate ceramics in vitro. J Biomed Mater Res B

24. Xie Y, Zheng X, Ding C, Zhai W, Chang J, and Ji H. Preparation and Characterization of CaO-ZrO2-SiO2 Coating for Potential Application in Biomedicine. J Thermal Spray Technol

25. Zhao W, Chang J, Wang J, Zhai W and Wang Z. In vitro bioactivity of novel tricalcium silicate ceramics. Journal of Materials Science: Materials in Medicine

26. Wang KW, Zhu YJ, Chen XY, Zhai W, Wang Q, Chen F, Chang J and Duan Y-R. Flower-like hierarchically nanostructured hydroxyapatite hollow spheres: facile preparation and application in anticancer drug cellular delivery. Chemistry – An Asian Journal

27. Ning C, Ding D, Dai K, Zhai W and Chen L. The effect of Zr content on the microstructure, mechanical properties and cell attachment of Ti–35Nb–xZr alloys. Biomed. Mater

28. Chen F, Tang QL, Zhu YJ, Wang KW, Zhang ML, Zhai W, Chang J. Hydroxyapatite nanorods/poly(vinyl pyrolidone) composite nanofibers, arrays and three-dimensional fabrics: Electrospun preparation and transformation to hydroxyapatite nanostructures. Acta Biomaterialia

29. Wanyin Zhai, Kaili Lin, Jiang Chang. Study on crosslinking of porcine heart valve matrix using procyanidins. The 8th Annual Meeting of Tissue Engineering Society Internation

30. 翟萬銀，常 江，趙 強，徐德明.組織工程心臟瓣膜研究進展，國外醫學.生物醫學工程學

31. 翟萬銀,朱振勤,陳季武,王雲丹,趙子寅,胡天喜.雷震子護康膠囊製劑抗氧化和對DNA損傷保護作用研究，發光學報

32. 朱振勤,翟萬銀,陳季武,夏晶,傅蓓蓓,謝萍,胡天喜.葡萄籽提取物抗氧化及對DNA保護作用研究，華東師範大學學報

33. Zhu ZQ, Zhai WY, Chen JW, Xia J, Xie P. Effects of grape seed procyanidin scavenging free radicals and protecting cultured bovine aortic cells from oxidative damage. Acta biochemica et biophysica sinica

34. Lin KL, Zhai WY, Ni SY, Chang J, Zeng Y, Qian W, Study of the mechanical property and in vitro biocompatibility of CaSiO3 ceramics, Ceramics International

35. Wenyuan Zhao, Junying Wang, Wanyin Zhai, Zheng Wang, Jiang Chang. The self-setting properties and in vitro bioactivity of tricalcium silicate.Biomaterials

36. Wu CT, Chang J, Zhai WY, A novel hardystonite bioceramic: preparation and characteristics, Ceramics International

37. Gou Z, Chang J, Zhai W, Preparation and characterization of novel bioactive dicalcium silicate ceramics. J. Eur. Ceram. Soc

38. Zhao L, Chang J, Zhai W. Effect of dissolution and different crystallographic phasephases of TiO2 on hepatocyte response in vitro. Journal of Biomaterials Applications

39. Gou Z, Chang J, Zhai W, Wang JY, Study on the self-setting property and the in vitro bioactivity of b-Ca2SiO4, Journal of Biomedical Materials Research Part B (JBMR:B), Applied Biomaterials

40. Wu CT, Chang J, Wang JY, Ni SY, Zhai WY, Preparation and Characteristics of a Calcium Magnesium Silicate (Bredigite) Bioactive Ceramic. Biomaterials

（1）常江，翟萬銀. 發明名稱“具有生物活性的人工生物瓣瓣膜的製備方法”.中國專利號

（2）常江，翟萬銀. 發明名稱“採用槲皮素交聯製備人工生物心臟瓣膜材料的方法”.中國專利申請號

（3）常江，翟萬銀. 發明名稱“一種可再細胞化的人工生物心臟瓣膜”.中國專利申請號