羅穩，（1983-），博士，教授，博士生導師。2011年畢業於中山大學藥學院，獲理學博士學位。隨後受聘於河南省天然藥物與免疫工程重點實驗室，研究方向為藥物化學、化學生物學。
基本介紹
- 中文名：羅穩
- 畢業院校：中山大學
- 學位/學歷：博士
- 職業：教師
個人簡介,研究方向,近期論文,
個人簡介
羅穩，（1983-），博士，教授，博士生導師。2011年畢業於中山大學藥學院，獲理學博士學位。隨後受聘於河南省天然藥物與免疫工程重點實驗室，研究方向為藥物化學、化學生物學。先後主持國家自然科學基金2項，中國博士後基金1項，以及河南省博士後基金、河南省科技廳、教育廳基金以及河南大學優青項目各1項。2018年獲得國家留學基金委訪問學者項目資助，於美國南佛羅里達大學莫菲特癌症研究中心訪問交流一年。獲得河南省青年骨幹教師，河南省優秀博士後，開封市科技創新人才，開封市第十四屆青年科技獎等。工作以來共發表SCI論文三十餘篇，授權國家發明專利6件。中國化學會及河南省化學會會員，省科學基金評審庫專家，多個期刊雜誌審稿人。
研究方向
抗老年痴呆、抗腫瘤藥物的設計合成及評價
近期論文
1. Wen Luo, Jianwu Lv, Ting Wang, Zhiyang Zhang, Huiyan Guo, Zhiyi Song, Jiechao Wang, Jing Ma*, Yiping Chen*, Synthesis, in vitro and in vivo biological evaluation of novel graveolinine derivatives as potential anti-Alzheimer agents. Bioorg. & Med. Chem.,2020, 28, 115190-115198.
2. Chen Hong, Huiyan Guo, Shuai Chen, Jianwu Lv, Xin Zhang, Yacheng Yang, Kang Huang, Yijuan Zhang, Zhiyong Tian,Wen Luo*, Yiping Chen*, Synthesis and biological evaluation of genistein-O-alkylamine derivatives as potential multifunctional anti-Alzheimer agents. Chem. Biol. Drug. Des.,2019, 93(2): 188-200.
3. Xiaojuan Xu, Senzhen Wang, Yuan Chang, Chaochao Ge, Xinna Li, Yongli Feng, Songqiang Xie, Chaojie Wang, Fujun Dai*,Wen Luo*, Synthesis and biological evaluation of novel asymmetric naphthalene diimide derivatives as anticancer agents depending on ROS generation, Med. Chem. Comm.,2018, 9, 1377-1385.
4. Yacheng Yang, Yongmei Zhao, Qingzhao Wang, Qianlei Ren, Shuangyu Shao,Wen Luo*, A naked eye recognition of reaction-based fluorescent probe for Cudetection, Fine Chemicals,2018: 35(4): 569-573.
5. Qian Li, Zi-xin Zhu, Xin Zhang,Wen Luo*, Li-ping Chang, Shuai Chen, Yu-xia Wang*, Song-qiang Xie, Cong-cong Chang, Chao-jie Wang*,The lead optimization of the polyamine conjugate of flavonoid with a naphthalene motif: Synthesis and biological evaluation, Eur. J. Med. Chem.,2018, 146, 564-576.
6. Juan Cen,Huiyan Guo, Chen Hong, Yacheng Yang, Ting Wang,Wen Luo*, Chaojie Wang*, Development of tacrine-bifendate conjugates with improved cholinesterase inhibitory and pro-cognitive efficacy and reduced hepatotoxicity, Eur. J. Med. Chem.,2018, 144, 128-136.
7. Wen Luo,Ting Wang, Chen Hong, Yacheng Yang, Ying Chen, Juan Cen*, Songqiang Xie, Chaojie Wang*, Design, synthesis and evaluation of 4-dimethylamine flavonoid derivatives as potential multifunctional anti-Alzheimer agents, Eur. J. Med. Chem.,2016, 122,17-26.
8. Qian Li, Yangyang Zhai,Wen Luo*,Zixin Zhun, Xin Zhang, Songqiang Xie*, Chen Hong, Yuxia Wang, Yabin Su, Jin Zhao, Chaojie Wang*, Synthesis and biological properties of polyamine modified flavonoids as hepatocellular carcinoma inhibitors, Eur. J. Med. Chem.,2016, 121, 110-119.
9. Wen Luo*,Ying Chen, Ting Wang, Chen Hong, Liping Chang, Congcong Chang, Yacheng Yang, Songqiang Xie, Chaojie Wang*, Design, synthesis and evaluation of novel 7-aminoalkyl-substituted flavonoid derivatives with improved cholinesterase inhibitory activities, Bioorg. Med. Chem.,2016, 24(4):672-680.
10. Xin Zhang, Jiang Wang, Chen Hong,Wen Luo*,Chaojie Wang*, Design, synthesis and evaluation of genisteinpolyamine conjugates as multi-functional anti-Alzheimer agents, Acta Pharm. Sinica B,2015, 5(1): 67-73.
