程亮，蘇州大學功能納米與軟物質研究院特聘教授，博士生導師。
基本介紹
- 中文名：程亮
- 職稱：教授
人物經歷,主要成果和技術貢獻,代表論文,
人物經歷
2019年入選國家級人才工程
2012年蘇州大學獲得博士學位，之後留校工作被聘為講師。
2014年7月晉升為副教授；
2017年8月晉升為研究員；
2019年11月晉升為特聘教授。
2015~2016年期間在美國威斯康辛大學-麥迪遜分校訪學交流。
主要成果和技術貢獻
近年來從材料科學領域出發，結合多學科交叉研究的優勢，在納米生物醫學等領域從事科學研究。發展了多種無機納米材料及其複合功能納米材料，利用其獨特的光學、磁學和X-射線吸收等性質，探索了針對腫瘤影像導航下的腫瘤光學治療和聯合治療，並證明了這些功能材料在實現精準治療和提高腫瘤治療的特異性等方面具有獨特的優勢。
從2009年起在國際學術期刊共發表學術論文174篇，論文SCI總他引17661次，SCI “H-index”為66（數據來自Web of science）。其中第一/通訊作者67篇，發表於Chem. Rev.（1篇）、Chem. Soc. Rev.（1篇）、Nat. Commun.（1篇）、J. Am. Chem. Soc.（1篇）、Angew. Chem. Int. Ed.（4篇）、Adv. Mater.（3篇）、Natl. Sci. Rev.（1篇）、Nano Today（2篇）、Mater. Hor.（2篇）、Nano Lett.（5 篇）、ACS Nano（6篇）、Adv. Funct. Mater.（5篇）、Small（4篇）、Biomaterials（4篇）等材料、化學領域權威期刊。29篇SCI論文被選為“ESI高被引論文”，最高單篇他引1295次。2017-2020連續四年入選美國科睿唯安公布的“全球高被引科學家名單”（Highly Cited Researchers）（材料）；2017-2019連續三年入選愛思唯爾發布的“中國高被引學者”（材料）。研究成果先後受到C&EN、Materials Views、Materials Views China和X-MOL等眾多媒體和網站的亮點報導。獲得國家自然科學區域發展聯合基金、青年基金及面上項目、江蘇省自然科學優秀青年基金等項目資助，併入選蘇州大學“仲英學者”、“東吳學者”、江蘇省333人才工程。擔任國際著名期刊雜誌《Journal of Nanobiotechnology》副主編（IF=6.518）。
代表論文
1. Zhou, Z.; Wang, X.; Zhang, H.; Huang, H.; Sun, L.; Ma, L.; Du, Y.; Pei, C.; Zhang, Q.; Li, H.; Ma, L.; Gu, L.; Liu, Z.; Cheng, L*.; Tan, C.*, Activating Layered Metal Oxide Nanomaterials via Structural Engineering as Biodegradable Nanoagents for Photothermal Cancer Therapy. Small 2021, ASAP.
2. Zhang, R.; Cheng, L.*; Dong, Z.; Hou, L.; Zhang, S.; Meng, Z.; Betzer, O.; Wang, Y.; Popovtzer, R.; Liu, Z.*; Ultra-small natural product based coordination polymer nanodots for acute kidney injury relief, Materials Horizons, 2021, ASAP.
3. Gong, F.; Cheng, L.*; Yang, N.; Gong, Y.; Ni, Y.; Bai, S.; Wang, X.; Chen, M.; Chen, Q.; Liu, Z.*, Preparation of TiH1.924 nanodots by liquid-phase exfoliation for enhanced sonodynamic cancer therapy. Nature Communications 2020,11 (1), 3712.
4. Wang, X.; Zhong, X.; Bai, L.; Xu, J.; Gong, F.; Dong, Z.; Yang, Z.; Zeng, Z.; Liu, Z.; Cheng, L.*, Ultrafine Titanium Monoxide (TiO1+x) Nanorods for Enhanced Sonodynamic Therapy. Journal of the American Chemical Society 2020,142 (14), 6527-6537.
5. Son, S.; Kim, J. H.; Wang, X.; Zhang, C.; Yoon, S. A.; Shin, J.; Sharma, A.*; Lee, M. H.*; Cheng, L.*; Wu, J.*; Kim, J. S.*, Multifunctional sonosensitizers in sonodynamic cancer therapy. Chemical Society Reviews 2020,49 (11), 3244-3261.
6. Cheng, L.*; Wang, X.; Gong, F.; Liu, T.; Liu, Z.*, 2D Nanomaterials for Cancer Theranostic Applications. Advanced Materials 2020,32 (13), 1902333.
7. Gong, F.; Yang, N.; Wang, X.; Zhao, Q.; Chen, Q.; Liu, Z.; Cheng, L.*, Tumor microenvironment-responsive intelligent nanoplatforms for cancer theranostics. Nano Today 2020,32, 100851.
8. Gong, F.; Chen, M.; Yang, N.; Dong, Z.; Tian, L.; Hao, Y.; Zhuo, M.; Liu, Z.; Chen, Q.*; Cheng, L.*, Bimetallic Oxide FeWOx Nanosheets as Multifunctional Cascade Bioreactors for Tumor Microenvironment-Modulation and Enhanced Multimodal Cancer Therapy. Advanced Functional Materials 2020,30 (49), 2002753.
9. Wang, X.; Zhong, X.; Liu, Z.; Cheng, L.*, Recent progress of chemodynamic therapy-induced combination cancer therapy. Nano Today 2020,35, 100946.
10. Wang, X.; Zhong, X.; Gong, F.; Chao, Y.; Cheng, L.*, Newly developed strategies for improving sonodynamic therapy. Materials Horizons 2020,7 (8), 2028-2046.
11. Wang, X.; Wang, X.; Zhong, X.; Li, G.; Yang, Z.; Gong, Y.; Liu, Z.*; Cheng, L.*, V-TiO2 nanospindles with regulating tumor microenvironment performance for enhanced sonodynamic cancer therapy. Applied Physics Reviews 2020,7 (4), DOI: 10.1063/5.0027606.
12. Wang, X.; Fan, L.; Cheng, L.*; Sun, Y.; Wang, X.; Zhong, X.; Shi, Q.; Gong, F.; Yang, Y.; Ma, Y.; Miao, Z.; Zha, Z.*, Biodegradable Nickel Disulfide Nanozymes with GSH-Depleting Function for High-Efficiency Photothermal-Catalytic Antibacterial Therapy. Iscience 2020,23 (7), 101281.
13. Wang, X.; Cheng, L.*, Multifunctional Prussian blue-based nanomaterials: Preparation, modification, and theranostic applications. Coordination Chemistry Reviews 2020,419.
14. Zhong, X.; Wang, X.; Cheng, L.*; Tang, Y. a.; Zhan, G.; Gong, F.; Zhang, R.; Hu, J.*; Liu, Z.; Yang, X.*, GSH-Depleted PtCu3 Nanocages for Chemodynamic- Enhanced Sonodynamic Cancer Therapy. Advanced Functional Materials 2020,30 (4). 1907954.
15. Yang, N.; Li, W.; Gong, F.; Cheng, L.*; Dong, Z.; Bai, S.; Xiao, Z.; Ni, C.*; Liu, Z.*, Injectable Nonmagnetic Liquid Metal for Eddy-Thermal Ablation of Tumors under Alternating Magnetic Field. Small Methods 2020,4 (9), 2000147.
16. Gong, F.; Yang, N.; Wang, Y.; Zhuo, M.; Zhao, Q.*; Wang, S.; Li, Y.; Liu, Z.; Chen, Q.; Cheng, L.*, Oxygen-Deficient Bimetallic Oxide FeWOX Nanosheets as Peroxidase-Like Nanozyme for Sensing Cancer via Photoacoustic Imaging. Small 2020,16 (46), 2003496.
17. Siwawannapong, K.; Zhang, R.; Lei, H.; Jin, Q.; Tang, W.; Dong, Z.; Lai, R.-Y.; Liu, Z.; Kamkaew, A.*; Cheng, L.*, Ultra-small Pyropheophorbide-a Nanodots for Near-infrared Fluorescence/Photoacoustic Imaging-guided Photodynamic Therapy. Theranostics 2020,10 (1), 62-73.
18. Lei, H.; Wang, X.; Bai, S.; Gong, F.; Yang, N.; Gong, Y.; Hou, L.; Cao, M.*; Liu, Z.; Cheng, L.*, Biodegradable Fe-Doped Vanadium Disulfide Theranostic Nanosheets for Enhanced Sonodynamic/Chemodynamic Therapy. ACS Applied Materials & Interfaces 2020,12 (47), 52370-52382.
19. Bai, S.; Yang, N.; Wang, X.; Gong, F.; Dong, Z.; Gong, Y.; Liu, Z.*; Cheng, L.*, Ultrasmall Iron-Doped Titanium Oxide Nanodots for Enhanced Sonodynamic and Chemodynamic Cancer Therapy. ACS Nano 2020,14 (11), 15119-15130.
20. Zhong, X.; Wang, X.; Zhan, G.; Tang, Y. a.; Yao, Y.; Dong, Z.; Hou, L.; Zhao, H.; Zeng, S.; Hu, J.*; Cheng, L*.; Yang, X.*, NaCeF4:Gd,Tb Scintillator as an X-ray Responsive Photosensitizer for Multimodal Imaging-Guided Synchronous Radio/Radiodynamic Therapy. Nano Letters 2019,19 (11), 8234-8244.
21. Zhang, R.; Fan, X.; Meng, Z.; Lin, H.; Jin, Q.; Gong, F.; Dong, Z.; Li, Y.; Chen, Q.; Liu, Z.; Cheng, L.*, Renal Clearable Ru-based Coordination Polymer Nanodots for Photoacoustic Imaging Guided Cancer Therapy. Theranostics 2019,9 (26), 8266-8276.
22. Xu, Y.; Wang, X.; Cheng, L.*; Liu, Z.; Zhang, Q.*, High-yield synthesis of gold bipyramids for in vivo CT imaging and photothermal cancer therapy with enhanced thermal stability. Chemical Engineering Journal 2019,378.
23. Xiao, J.; Cheng, L.*; Fang, T.; Zhang, Y.; Zhou, J.; Cheng, R.; Tang, W.; Zhong, X.; Lu, Y.; Deng, L.; Cheng, Y.*; Zhu, Y.; Liu, Z.; Cui, W.,* Nanoparticle-Embedded Electrospun Fiber-Covered Stent to Assist Intraluminal Photodynamic Treatment of Oesophageal Cancer. Small 2019,15 (49).
24. Wang, X.; Zhong, X.; Lei, H.; Geng, Y.; Zhao, Q.*; Gong, F.; Yang, Z.; Dong, Z.; Liu, Z.; Cheng, L.*, Hollow Cu2Se Nanozymes for Tumor Photothermal-Catalytic Therapy. Chemistry of Materials 2019,31 (16), 6174-6186.
25. Wang, X.; Cheng, L.*, Multifunctional two-dimensional nanocomposites for photothermal-based combined cancer therapy. Nanoscale 2019,11 (34), 15685-15708.
26. Tang, W.; Dong, Z.; Zhang, R.; Yi, X.; Yang, K.; Jin, M.; Yuan, C.;* Xiao, Z.*; Liu, Z.; Cheng, L.*, Multifunctional Two-Dimensional Core-Shell MXene@Gold Nanocomposites for Enhanced Photo-Radio Combined Therapy in the Second Biological Window. ACS Nano 2019,13 (1), 284-294.
27. Liu, T.; Shen, S.; Huang, Y.; Zhang, X.; Lai, Z.; Ha Tran, T.; Liu, Z.; Cheng, L.*, Controllable growth of Au nanostructures onto MoS2 nanosheets for dual-modal imaging and photothermal-radiation combined therapy. Nanoscale 2019,11 (47), 22788-22795.
28. Gong, F.; Cheng, L.*; Yang, N.; Betzer, O.; Feng, L.; Zhou, Q.; Li, Y.; Chen, R.; Popovtzer, R.; Liu, Z.*, Ultrasmall Oxygen-Deficient Bimetallic Oxide MnWOX Nanoparticles for Depletion of Endogenous GSH and Enhanced Sonodynamic Cancer Therapy. Advanced Materials 2019,31 (23)，1900730.
29. Wu, C.; Zhang, R.; Du, W.; Cheng, L.*; Liang, G.*, Alkaline Phosphatase-Triggered Self-Assembly of Near-Infrared Nanoparticles for the Enhanced Photoacoustic Imaging of Tumors. Nano Letters 2018,18 (12), 7749-7754.
30. Jin, Q.; Liu, J.; Zhu, W.; Dong, Z.; Liu, Z.; Cheng, L.*, Albumin-Assisted Synthesis of Ultrasmall FeS2 Nanodots for Imaging-Guided Photothermal Enhanced Photodynamic Therapy. Acs Applied Materials & Interfaces 2018,10 (1), 332-340.
31. Gong, F.; Cheng, L.*; Yang, N.; Jin, Q.; Tian, L.; Wang, M.; Li, Y.; Liu, Z.*, Bimetallic Oxide MnMoOx Nanorods for in Vivo Photoacoustic Imaging of GSH and Tumor-Specific Photothermal Therapy. Nano Letters 2018,18 (9), 6037-6044.
32. Shen, S.; Jiang, D.; Cheng, L.*; Chao, Y.; Nie, K.; Dong, Z.; Kutyreff, C. J.; Engle, J. W.; Huang, P.; Cai, W.*; Liu, Z.*, Renal-Clearable Ultrasmall Coordination Polymer Nanodots for Chelator-Free Cu-64-Labeling and Imaging-Guided Enhanced Radiotherapy of Cancer. ACS Nano 2017,11 (9), 9103-9111.
33. Shen, S.; Chao, Y.; Dong, Z.; Wang, G.; Yi, X.; Song, G.; Yang, K.; Liu, Z.; Cheng, L.*, Bottom-Up Preparation of Uniform Ultrathin Rhenium Disulfide Nanosheets for Image-Guided Photothermal Radiotherapy. Advanced Functional Materials 2017,27 (28), 1700250.
34. Jin, Q.; Zhu, W.; Jiang, D.; Zhang, R.; Kutyreff, C. J.; Engle, J. W.; Huang, P.; Cai, W.*; Liu, Z.; Cheng, L.*, Ultra-small iron-gallic acid coordination polymer nanoparticles for chelator-free labeling of Cu-64 and multimodal imaging-guided photothermal therapy. Nanoscale 2017,9 (34), 12609-12617.
35. Hao, J.; Song, G.; Liu, T.; Yi, X.; Yang, K.; Cheng, L.*; Liu, Z.*, In Vivo Long-Term Biodistribution, Excretion, and Toxicology of PEGylated Transition-Metal Dichalcogenides MS2 (M = Mo, W, Ti) Nanosheets. Advanced Science 2017,4 (1), 1600160.
36. Cheng, L.*; Shen, S.; Jiang, D.; Jin, Q.; Ellison, P. A.; Ehlerding, E. B.; Goel, S.; Song, G.; Huang, P.; Barnhart, T. E.; Liu, Z.*; Cai, W.*, Chelator-Free Labeling of Metal Oxide Nanostructures with Zirconium-89 for Positron Emission Tomography Imaging. ACS Nano 2017,11 (12), 12193-12201.
37. Cheng, L.*; Jiang, D.; Kamkaew, A.; Valdovinos, H. F.; Im, H.-J.; Feng, L.; England, C. G.; Goel, S.; Barnhart, T. E.; Liu, Z.; Cai, W.*, Renal-Clearable PEGylated Porphyrin Nanoparticles for Image-Guided Photodynamic Cancer Therapy. Advanced Functional Materials 2017,27 (34), 1702928.
38. Chen, Y.; Cheng, L.*; Dong, Z.; Chao, Y.; Lei, H.; Zhao, H.; Wang, J.; Liu, Z.*, Degradable Vanadium Disulfide Nanostructures with Unique Optical and Magnetic Functions for Cancer Theranostics. Angewandte Chemie International Edition 2017,56 (42), 12991-12996.
39. Xuan, J.; Wang, Z.; Chen, Y.; Liang, D.; Cheng, L.*; Yang, X.; Liu, Z.; Ma, R.; Sasaki, T.; Geng, F.*, Organic-Base-Driven Intercalation and Delamination for the Production of Functionalized Titanium Carbide Nanosheets with Superior Photothermal Therapeutic Performance. Angewandte Chemie International Edition 2016,55 (47), 14569-14574.
40. Liu, T.; Chao, Y.; Gao, M.; Liang, C.; Chen, Q.; Song, G.; Cheng, L.*; Liu, Z.*, Ultra-small MoS2 nanodots with rapid body clearance for photothermal cancer therapy. Nano Research 2016,9 (10), 3003-3017.
41. Cheng, L.; Shi, S.; Shen, S.; Barnhart, T.; Cai, W.*; Liu, Z., FeSe2-Decorated Bi2Se3 Nanosheets for Chelator-Free Cu-labeling and Multimodal Image-Guided Photothermal-Radiation Therapy. Journal of Nuclear Medicine 2016,57.
42. Cheng, L.*; Shen, S.; Shi, S.; Yi, Y.; Wang, X.; Song, G.; Yang, K.; Liu, G.; Barnhart, T. E.; Cai, W.*; Liu, Z.*, FeSe2-Decorated Bi2Se3 Nanosheets Fabricated via Cation Exchange for Chelator-Free Cu--Labeling and Multimodal Image-Guided Photothermal-Radiation Therapy. Advanced Functional Materials 2016,26 (13), 2185-2197.
43. Cheng, L.*; Kamkaew, A.; Sun, H.; Jiang, D.; Valdovinos, H. F.; Gong, H.; England, C. G.; Goel, S.; Barnhart, T. E.; Cai, W.*, Dual-Modality Positron Emission Tomography/Optical Image-Guided Photodynamic Cancer Therapy with Chlorin e6-Containing Nanomicelles. ACS Nano 2016,10 (8), 7721-7730.
44. Cheng, L.; Kamkaew, A.; Shen, S.; Valdovinos, H. F.; Sun, H.; Hernandez, R.; Goel, S.; Liu, T.; Thompson, C. R.; Barnhart, T. E.; Liu, Z.*; Cai, W.*, Facile Preparation of Multifunctional WS2/WOx Nanodots for Chelator-Free Zr-89-Labeling and In Vivo PET Imaging. Small 2016,12 (41), 5750-5758.
45. Cheng, L.; Kamkaew, A.; Shen, S.; Valdovinos, H.; Barnhart, T.; Cai, W.*; Liu, Z., Chelator-Free Zr-labeling of Ultra-small WS2/WOx Quantum Dots for PET Imaging. Journal of Nuclear Medicine 2016,57.
46. Chao, Y.; Wang, G.; Liang, C.; Yi, X.; Zhong, X.; Liu, J.; Gao, M.; Yang, K.*; Cheng, L.*; Liu, Z.*, Rhenium-188 Labeled Tungsten Disulfide Nanoflakes for Self-Sensitized, Near-Infrared Enhanced Radioisotope Therapy. Small 2016,12 (29), 3967-3975.
