有機化學博士， 海南大學生物醫學工程學院副研究員，碩士生導師，海南省拔尖人才。
基本介紹
- 中文名：秦天依
- 國籍：中國
- 民族：漢
- 出生日期：1989年9月
- 畢業院校：中國科學院大學
- 職業：科研人員
個人簡介,學術經歷,學術論著,榮譽獎勵,科研項目,
個人簡介
2012年本科畢業於南開大學，2017年博士畢業於中國科學院理化技術研究所，2017-2022年先後在深圳大學、華南農業大學開展博士後研究工作，現為海南大學生物醫學工程學院副研究員(分子靶向成像團隊)。研究方向包括：（1）功能螢光染料及生化套用，（2）螢光探針用於高毒性、致病性有害物的現場檢測、生物成像，（3）基於螢光分析法面向醫學中慢性疾病標誌物的即時檢測。
學術經歷
2017-2022：博士後 深圳大學、華南農業大學
2012-2017：碩博 中國科學院理化技術研究所合成光化學實驗室(導師：李嫕)
2008-2012：本科 南開大學化學院
學術論著
(33) Ze-Jun Li, Cai-Yun Wang, Liang Xu, Zhen-Yu Zhang, Ying-Hao Tang, Tian-Yi Qin *, Ya-Long Wang. A ratiometric fluorescent indicator-displacement assay for on-site determination and intracellular imaging of nitroxinil. Biosensors, 2023, 13(7), 752.
(32) Chao Song, Conghui Zeng, Tianyi Qin *, Taoyuze Lv, Zhongyong Xu, Zhiqing Xun, Lei Wang, Xiaoqiang Chen, Bin Liu *, and Xiaojun Peng. A dual-state-emission chalcone-based supramolecular probe for ratiometric detection of penconazole in environmental samples. Chemical Engineering Journal, 2023, 143610.
(31) Conghui Zeng, Zhongyong Xu*, Chao Song, Tianyi Qin, Tianhao Jia, Chen Zhao, Lei Wang, Bin Liu*, Xiaojun Peng. Naphthalene-based fluorescent probe for on-site detection of hydrazine in the environment. Journal of Hazardous Materials, 2023, 445, 130415.
(30) Zhongyong Xu, Conghui Zeng, Yutian Zhao, Mei Zhou, Taoyuze Lv, Chao Song, Tianyi Qin, Lei Wang, Bin Liu*, Xiaojun Peng. Smartphone-based on-site detection of hydrogen peroxide in milk by using a portable ratiometric fluorescent probe. Food Chemistry, 2023, 410, 135381.
(29) Tianyi Qin, Xiongfei Zhao, Chao Song, Taoyuze Lv, Shihong Chen, Zhiqing Xun, Zhongyong Xu, Zhixiang Zhang, Hanhong Xu, Chen Zhao, Bin Liu*, and Xiaojun Peng. A ratiometric supramolecular fluorescent probe for on-site determination of cyfluthrin in real food samples. Chemical Engineering Journal, 2023, 451, 139022.
(28) Tianhao Jia, Chunmei Pu, Tianyi Qin*, Bin Liu, Guangkai Yao, Zhiqing Xun, Bingfeng Wang, Yongqing Tian, Zhixiang Zhang*, Hanhong Xu*, Chen Zhao*. Azocalixarene-Based Supramolecular System for the Detection of Paraquat via an Improved Indicator Displacement Assay. Journal of Agricultural and Food Chemistry, 2022, 70(50), 15981–15989.
(27) Bin Liu*, Mei Zhou, Yingying Huang, Bing Du, Lei Wang, Zhongyong Xu*, Tianyi Qin*, Xiaojun Peng. Rapid and ratiometric fluorescent detection of phosgene by a red-emissive ESIPT-basedbenzoquinolone probe. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2022, 281, 121619.
(26) Tianyi Qin*, Xiongfei Zhao, Tianhao Jia, Shufan Si, Zhongyong Xu, Bin Liu, Hanhong Xu*, and Chen Zhao*. A surfactant-assisted approach enables the fluorescence tracking of benfluralin in plants. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2022, 280, 121517.
(25) Tianyi Qin, Xiongfei Zhao, Tianhao Jia, Xinfeng Du, Taoyuze Lv, Yongqing Tian, Zhixiang Zhang, Bin Liu*, Hanhong Xu*, and Chen Zhao*. A novel protein-based supramolecular recognition approach for ratiometric fluorescence detection of fipronil. Sensors and Actuators B: Chemical, 2022, 369, 132358.
(24) Tianyi Qin, Xiongfei Zhao, Taoyuze Lv, Guangkai Yao, Zhongyong Xu, Lei Wang, Chen Zhao*, Hanhong Xu*, Bin Liu*, and Xiaojun Peng. General method for pesticide recognition using albumin-based host-guest ensembles. ACS sensors, 2022, 7(7), 2020-2027. (IF: 9.6)
(23) Kangning Zhu, Siyuan Qian, Hanwen Guo, Qingying Wang, Xiaoying Chu, Xinyi Wang, Si Lu, Yaou Peng, Yishun Guo, Zhongqiang Zhu, Tianyi Qin, Bin Liu, Ying-Wei Yang, Bailiang Wang*. pH-Activatable Organic Nanoparticles for Efficient Low-Temperature Photothermal Therapy of Ocular Bacterial Infection. ACS nano, 2022, 16(7), 11136-11151.
(22) Bin Liu, Conghui Zeng, Danna Zheng, Xiongfei Zhao, Chao Song, Tianyi Qin, Zhongyong Xu*. A near-infrared dicyanoisophorone-based fluorescent probe for discriminating HSA from BSA. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2022, 274, 121081.
(21) Bin Liu, Xiongfei Zhao, Mei Zhou, Chao Song, Conghui Zeng, Tianyi Qin, Mingyuan Zhang, Zhongyong Xu*. Modulating donor of dicyanoisophorone-based fluorophores to detect human serum albumin with NIR fluorescence. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2022, 268, 120666.
(20) Xiongfei Zhao, Weidong Zheng, Tianyi Qin*, Xinfeng Du, Yanmei Lei, Taoyuze Lv, Mei Zhou, Zhongyong Xu, Lei Wang, Bin Liu*, and Xiaojun Peng. An anti-interference fluorescent probe for point-of-care diagnosis of albuminuria. Sensors and Actuators B: Chemical, 2022, 351, 130980.
(19) Bin Liu, Taoyuze Lv, Xiongfei Zhao, Mei Zhou, Chao Song, Conghui Zeng, Tianyi Qin, Zhongyong Xu*. Fluorescence discrimination of HSA from BSA: A close look at the albumin-induced restricted intramolecular rotation of flavonoid probe. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2022, 264, 120306.
(18) Zhongyong Xu, Xiongfei Zhao, Mei Zhou, Zhijun Zhang, Tianyi Qin, Dong Wang, Lei Wang, Xiaojun Peng, Bin Liu*. Donor engineering on flavonoid-based probes to enhance the fluorescence brightness in water: Design, characterization, photophysical properties, and application for cysteine detection. Sensors and Actuators B: Chemical, 2021, 345, 130367.
(17) Zhongyong Xu, Shufan Si, Zhijun Zhang, Huiya Tan, Tianyi Qin, Zhonglin Wang, Dong Wang, Lei Wang, Bin Liu*. A fluorescent probe with dual acrylate sites for discrimination of different concentration ranges of cysteine in living cells. Analytica Chimica Acta, 2021, 1176, 338763.
(16) Tianyi Qin, Bin Liu*, Zhongyong Xu, Guangkai Yao, Hanhong Xu*, and Chen Zhao*. Flavonol-based small-molecule fluorescent probes. Sensors and Actuators B: Chemical, 2021, 129718. (IF: 9.2)
(15) Zhonglin Wang, Shufan Si, Zijie Luo, Tianyi Qin, Zhongyong Xu, Bin Liu*. An AIE-based Fluorescent Probe for Detection of Picric Acid in Water. Chemistry Letters, 2021, 50(1), 103-105.
(14) Qiuqin Lai, Shufan Si, Tianyi Qin, Benjie Li, Hanxiang Wu, Bin Liu*, Hanhong Xu*, Chen Zhao*. A novel red-emissive probe for colorimetric and ratiometric detection of hydrazine and its application in plant imaging. Sensors and Actuators B: Chemical, 2020, 307, 127640.
(13) Tianyi Qin, Bin Liu*, Bing Du, Yingying Huang, Guangkai Yao, Zhiqing Xun, Hanhong Xu*, and Chen Zhao*. Solvatofluorochromic flavonoid dyes with enlarged transition dipole moments enable ratiometric detection of methanol in commercial biodiesel with improved sensitivities. Journal of Materials Chemistry C, 2020, 8(47), 16808-16814.
(12) Yingying Huang, Taoyuze Lv, Tianyi Qin, Zhongyong Xu, Lei Wang, Bin Liu*. A DS2-specific flavonoid-based probe with a unique dual-emissive response to human serum albumin. Chemical Communications, 2020, 56(75) 11094-11097.
(11) Zhongyong Xu, Tianyi Qin, Xianfeng Zhou*, Lei Wang, Bin Liu*. Fluorescent probes with multiple channels for simultaneous detection of Cys, Hcy, GSH, and H2S. TrAC Trends in Analytical Chemistry, 2019, 121, 115672.
(10) Yingying Huang, Jiawen He, Tianyi Qin, Xiongzhi Xiang, Bin Liu*, Lei Wang*. Fluorescence determination of ethanol-gasoline blends without the aid of excitation-emission matrix fluorescence. Chemistry Letters, 2019, 48(11), 1383-1386.
(9) Tianyi Qin, Yingying Huang, Kangning Zhu, Jiahao Wang, Chengjun Pan, Bin Liu*, and Lei Wang*. A flavonoid-based fluorescent test strip for fast and selective detection of a gaseous nerve agents simulant. Analytica Chimica Acta, 2019,1076,125-130.
(8) Kangning Zhu, Taoyuze Lv, Tianyi Qin, Yingying Huang, Lei Wang, Bin Liu*. A flavonoid-based fluorescent probe enables the accurate quantification of human serum albumin by minimizing the interference from blood lipids. Chemical Communications, 2019, 55(93), 13983-13986.
(7) Tianyi Qin, Bin Liu*, Yingying Huang, Kuan Yang, Kangning Zhu, Zijie Luo, Chengjun Pan, and Lei Wang*. Ratiometric fluorescent monitoring of methanol in biodiesel by using an ESIPT-based flavonoid probe. Sensors and Actuators B: Chemical, 2018, 277, 484-491.
(6) Kangning Zhu, Tianyi Qin, Chen Zhao, Zijie Luo, Yingying Huang, Bin Liu*, Lei Wang*. A novel fluorescent turn-on probe for highly selective detection of nitroreductase in tumor cells. Sensors and Actuators B: Chemical, 2018, 276, 397-403.
(5) Zijie Luo, Bin Liu*, Tianyi Qin, Kangning Zhu, Chen Zhao, Chengjun Pan, Lei Wang*. Cyclization of chalcone enables ratiometric fluorescence determination of hydrazine with a high selectivity. Sensors and Actuators B: Chemical, 2018, 263, 229-236.
(4) Tianyi Qin, Bin Liu*, Kangning Zhu, Zijie Luo, Yingying Huang, Chengjun Pan, and Lei Wang*. Organic fluorescent thermometers: Highlights from 2013 to 2017. TrAC-Trends in Analytical Chemistry, 2018, 102, 259-271. (IF: 8.4)
(3) Tianyi Qin, Yi Zeng, Jinping Chen, Tianjun Yu, Yi Li*. Pyrenyl peripheral-decorated polyamidoamine dendrimer for fluorescent temperature detection in aqueous phase. Acta Chimica Sinica, 2017, 75(1), 99-104.
(2) Tianyi Qin, Yi Zeng, Jinping Chen, Tianjun Yu, Yi Li*. Progress in Organic Fluorescent Thermometers. Acta Chimica Sinica, 2017, 75(12), 1164-1172.
(1) Tianyi Qin, Xuying Li, Jinping Chen*, Yi Zeng, Tianjun Yu, Guoqiang Yang, Yi Li*. Dendritic Ionic Liquids Based on Imidazolium‐Modified Poly (aryl ether) Dendrimers. Chemistry–An Asian Journal, 2014, 9, 3641-3649.
榮譽獎勵
- 獲中科院第二屆（京區）青年技術能手大賽(化學組)離子檢測單項獎，團體一等獎。
- 獲選2019年“博士後國際交流計畫”學術交流項目(第一批)。
科研項目
國家自然科學基金委地區科學基金項目(22364012), 2024.01~2027.12，主持，在研。
國家自然科學基金委青年項目(32102243), 2022.01~2024.12, 主持，在研。
中國博士後基金會, 面上項目(2021M691084), 2022.01~2023.12, 主持，結題。
