白芳，女，漢族，畢業於吉林大學，現任南開大學藥學院副教授，主要研究微生物與生化藥物。
基本介紹
- 中文名：白芳
- 職業：南開大學藥學院副教授
- 畢業院校：吉林大學
- 性別：女
人物經歷,研究方向,主要貢獻,
人物經歷
1999年9月至2003年7月就讀于吉林大學生命科學學院生物製藥專業，2003年9月考入南開大學微生物學系攻讀研究生，2008年7月獲得理學博士學位後留校任教。
研究方向
微生物藥物高通量篩選，基於結構基因或蛋白的藥物分子設計。
主要貢獻
1. Limei Ren, Xiaofang Cao, Peng Geng, Fang Bai*, Gang Bai. Study of the inhibition of two human maltase-glucoamylases catalytic domains by different α-glucosidase inhibitors. Carbohydrate Research, 2011, 346: 2688-2692.
2. Peng Meng, Yuanqiang Guo, Qi Zhang, Jie Hou, Fang Bai*, Peng Geng, Gang Bai. A novel amino-oligosaccharide isolated from the culture of Streptomyces strain PW638 is a potent inhibitor of α-amylase. Carbohydrate Research, 2011, 346: 1898-1902.
3. Xiaohong Qin, Limei Ren, Xue Yang, Fang Bai, Lele Wang, Peng Geng, Gang Bai, Yuequan Shen. Structures of human pancreatic a-amylase in complex with acarviostatins: Implications for drug design against type II diabetes. Journal of Structural Biology, 2011, 174: 196-202.
4. Limei Ren, Xiaohong Qin, Xiaofang Cao, LeleWang, Fang Bai, Gang Bai, Yuequan Shen. Structural insight into substrate specificity of human intestinal maltase-glucoamylase. Protein & Cell, 2011, 2(10): 827–836.
5. Fang Bai, Haijin Xu, Qi Zhang, Xizhen Qi, Rui Mou, Gang Bai, Mingqiang Qiao. Functional characterization of pfm in protein secretion and lung infection of Pseudomonas aeruginosa. Canadian Journal of Microbiology, 2011, 57: 829-837.
6. Rui Mou, Fang Bai, Qiaonan Duan, Xuehan Wang, Haijin Xu, Yanling Bai, Xiuming Zhang, Shouguang Jin, Mingqiang Qiao. Mutation of pfm affects the adherence of Pseudomonas aeruginosa to host cells and the quorum sensing system. FEMS Microbiology Letters, 2011, 324(2):173-80.
7. Peng Geng, Gang Bai, Xiansheng Meng, Fang Bai, Guoan Luo. Screening for metabolites of acarviostatin family aminooligosaccharides in rats using ultraperformance liquid chromatography coupled with electrospray ionization tandem mass spectrometry. Journal of Pharmaceutical and Biomedical Analysis, 2009, 50: 917–923.
8. Fang Bai, Yingli Li, Haijing Xu, Huiming Xia, Tengfei Yin, Hongming Yao, Lu Zhang, Xiuming Zhang, Yanling Bai, Shouguang Jin and Mingqiang Qiao. Identification and functional characterization of pfm, a novel gene involved in swimming motility of Pseudomonas aeruginosa. Gene, 2007, 401: 19-27.
先後主持南開大學青年教師研究資助項目、天津市自然科學基金、國家自然科學基金，並參與國家高技術研究發展計畫(863計畫)等項目。
