申恩志，河北秦皇島人，生物化學與分子生物學理學博士學位，現為西湖大學生命科學學院教師。
申恩志課題組致力於使用不同的實驗手段（分子生物學、生物化學、分析化學、生物信息學和遺傳學等），來研究非編碼RNA的分子機制和生理功能以及在重大疾病發生中的作用。
基本介紹
- 中文名：申恩志
- 職業：科研工作者，大學教師
- 學歷：博士研究生
個人簡介,代表論文,
個人簡介
2015年在麻省大學醫學院RNA治療研究所、諾貝爾獎得主Craig C. Mello實驗室從事博士後研究，並得到Charles King獎學金支持。申恩志博士主要致力於非編碼RNA的作用機制和生物學功能研究，曾以第一作者在Cell, Nature, Experimental Cell Research等雜誌發表多篇學術論文。
2019年加入西湖大學任研究員，組建非編碼核酸生物學實驗室。
代表論文
1.En-zhi Shen, Hao Chen, Ahmet R. Ozturk, Shikui Tu, Masaki Shirayama, Wen Tang, Yue-He Ding, Si-Yuan Dai, Zhiping Weng, Craig C. Mello, “Identification of piRNA binding sites reveals the Argonaute regulatory landscape of the C. elegans germline”,Cell,172, 1-15 (2018). PMID: 29456082 （F1000推薦）
2.Meetu Seth, Masaki Shirayama, Wen Tang,En-zhi Shen, Shikui Tu, Heng-Chi Lee, Zhiping Weng, Craig C. Mello, “The coding regions of germline mRNAs confer sensitivity to Argonaute regulation inC. elegans”,Cell report, 22, 1-11 (2018). PMID: 29456100
3.Wen Tang, Meetu Seth, Shikui Tu,En-Zhi Shen, Qian Li, Masaki Shirayama, Zhiping Weng, Craig C.Mello,“A sex chromosome piRNA promotesrobust dosage compensation and sex determination inC. elegans”,Development Cell,44, 1-9 (2018). PMID: 29456136
4.Takao Ishidate, Ahmet R. Ozturk, Daniel J. Durning, Rita Sharma,En-zhi Shen, Hao Chen, Meetu Seth, Masaki Shirayama and Craig C. Mello, “ZNFX-1 functions within perinuclear nuage to balance epigenetic signals”,Molecular Cell, 70, 639-649 (2018).PMID: 29775580
5.En-Zhi Shen, Chun-Qing Song, Yuan Lin, Wen-Hong Zhang, Pei-Fang Su, Wen-Yuan Liu, Pan Zhang, Jiejia Xu, Na Lin, Cheng Zhan, Xianhua Wang, Yu Shyr, Heping Cheng, Meng-Qiu Dong, “Mitoflash frequency in early adulthood predicts lifespan inCaenorhabditis elegans”,Nature, 508, 128-132 (2014)PMID: 24522532（F1000推薦）
6.Ling-Ling Sun, Ming Li, Fang Suo, Xiao-Man Liu,En-Zhi Shen, Bing Yang, Meng-Qiu Dong, Wan-Zhong He, Li-Lin Du, “Global Analysis of Fission Yeast Mating Genes Reveals New Autophagy Factors”PLos Genetics, 2013, 9(8):e1003715.PMID: 23950735
7.En-Zhi Shen, Yan Lei, Qian Liu, Yan-Bo Zheng, Chun-Qing Song, Jan Marc, Yong-Chao Wang, Le Sun, Qian-Jin Liang, “Identification and characterization of INMAP, a novel interphase nucleus and mitotic apparatus protein that is involved in spindle formation and cell cycle progression”Experimental Cell Research, 2009, 315, 1100-1116.PMID:19331820
