田占莊,男,博士,復旦大學基礎醫學院副教授、碩士生導師。
基本介紹
- 中文名:田占莊
- 畢業院校:復旦大學
- 學位/學歷:博士
- 職業:教師
- 專業方向:女童性早熟的發病機制及中西醫結合治療性早熟的神經生物學機制
- 就職院校:復旦大學基礎醫學院
研究方向,個人經歷,學習經歷,工作經歷,學術成果,榮譽獎項,
研究方向
- 女童性早熟的發病機制及中西醫結合治療性早熟的神經生物學機制
- 針刺調節下丘腦-垂體-腎上腺軸功能紊亂的神經生物學機制
個人經歷
學習經歷
河北醫科大學臨床醫學本科(1985-1990),北京中醫藥大學中西醫結合基礎碩士(1993-1996),復旦大學中西醫結合基礎博士(2000-2003)。
工作經歷
河北省承德醫學院解剖教研室助教(1990-1997)、講師(1997-2003),復旦大講師(2003-2007)、副教授(2007-至今);2005-2006年作為訪問學者在美國密蘇里堪撒斯城大學藥學院藥理系進修。中國神經科學學會會員、中國中西醫結合學會兒科專業委員會委員、中國針灸學會針刺麻醉分會副秘書長。
學術成果
主持或參與多項國家重點基礎研究計畫(973)和國家自然科學基金課題。目前在研國家自然科學基金一項(No. 81273894,NKB/dynorphin參與kisspeptin /GPR54介導的滋陰瀉火中藥合劑治療性早熟的神經機制, 70萬元,2013.1—2016.12);國家重點基礎研究計畫(973)課題一項(2013CB531906針藥複合麻醉機體保護機制研究)。
1.Shiran Wang, Liting Zhu, Jian Yu,Zhanzhuang Tian. Effect of Nourishing“Yin”-removing “Fire” Chinese herbal mixture on hypothalamic NKB/NK3R expression in female precocious rats. Evidence-Based Complementary and Alternative Medicine 2014, Article ID 217424
2. Jing Li, Yanyan Sun, Shiran Wang, Jian Yu,Zhanzhuang Tian. Effects of Nourishing “Yin”-Removing “Fire” Chinese Herb Mixture on the Differential Expression of GABAA Receptor α Subunits in Hypothalamus of Precocious Puberty Female Rats. Chinese Medicine, 2013, 4, 87-96
3. Yan Sun, Jian Yu, Boying Chen ,Zhanzhuang Tian. Effect of Nourishing ″Yin″- Removing ″Fire″ Chinese herb mixture on the hypothalamic kisspeptin expression in precocious rats. Journal of Ethnopharmacology, 2010,127:274-279
4. Li Sun,Zhanzhuang Tian, Jianping Wang. A direct cross-talk between interferon-c and sonic hedgehog signaling that leads to the proliferation of neuronal precursor cells. Brain, Behavior, and Immunity 24 (2010) 220–228
5. Hua Zhang,Zhanzhuang Tian, Jianping Wang. Behavioral evaluation of transgenic mice with CNS expression of IFN-a by elevated plus-maze and Porsolt swim test . Neurosci Lett. 2010,479: 287-291.
6. Yan Sun,Zhan-Zhuang Tian, Hong Zhao, Stephen TC Wong, Bo-Ying Chen. Characteristic of hypothalamic kisspeptin expression in the pubertal development of precocious female rats. Neurosci Lett. 2007,420:12-17.
7.Zhan-Zhuang Tian, Hong Zhao, Bo-Ying Chen. Evaluation of the true precocious puberty rats induced by neonatal administration of Danazol: Therapeutic effects of nourishing “Yin”- removing “Fire” Chinese herb mixture. Reprod Biol & Endocrin 2005,3:38.
8.Zhan-Zhuang Tian, Hong Zhao, Bo-Ying Chen. Decreased hypothalamic aromatase in female rats of precocious puberty. Neurosci Lett, 2004, 366(1): 92-96.
9. Hong Zhao,Zhan-Zhuang Tian, Jun-Wei Hao, Bo-Ying Chen. Extragonadal aromatization increases with time after ovariectomy in rat. Reprod Biol & Endocrin, 2005, 3:6.
10. Hong Zhao,Zhan-Zhuang Tian, Bo-Ying Chen. Brain aromatization may involve in electroacupuncture enhancing hypofunction of hypothalamus- pituitary - ovary axis in ovariectomized rats. Brain Res, 2005, 1037 (1-2):164-170.
11. Hong Zhao,Zhan-Zhuang Tian, Yi Feng, Bo-Ying Chen. Circulating estradiol and hypothalamic corticotrophin releasing hormone enhances along with time after ovariectomy in rats: effects of electroacupuncture. Neuropeptides 2005, 39(4): 433-438.
12. Hong Zhao,Zhan-Zhuang Tian, Bo-Ying Chen. Increased corticortropin- releasing hormone release in ovariectomized rats’ paraventricular nucleus: effects of electroacupuncture. Neurosci Lett, 2003, 353(1): 37-40.
13. Hong Zhao,Zhan-Zhuang Tian, Bo-Ying Chen. An important role of corticotropin-releasing hormone in electroacupuncture normalizing the subnormal function of hypothalamus- pituitary-ovary axis in ovariectomized rats. Neurosci Lett, 2003, 349(1): 25-28
14.田占莊,趙 宏,陳伯英. 滋陰瀉火中藥對性早熟模型大鼠促性腺激素釋放激素及其受體mRNA表達的影響 中國中西醫結合雜誌2003,23(9): 700-704.
15.田占莊,趙 宏,陳伯英. 達那唑誘導的雌性性早熟大鼠GnRH及其受體mRNA的表達 中華內分泌代謝雜誌 2003,19(3): 229-231.
16. 陳姍姍,俞健,田占莊. 曲譜瑞林治療真性性早熟的中樞機制 中國新藥與臨床雜誌 2009 28(2):134-137。
17. 張彥,馬淑蘭,陳伯英,田占莊. 針刺對急性手術創傷大鼠下丘腦CRF家族肽及其受體表達的影響,針刺研究,2010, 35(3):163-169.
18. 朱黎婷,田占莊.電針對急性手術創傷大鼠海馬及下丘腦促腎上腺皮質激素釋放因子表達的影響[J]. 針刺研究, 2013, 38(5):369-374
19.田占莊,張立鳳,朱培純. 兩種慢性痛大鼠脊髓和脊神經節一氧化氮合酶的表達及電針的影響. 承德醫學院學報 2001,18(3) 198-201.
20.田占莊,張立鳳,朱培純.兩種慢性痛大鼠脊神經節生長抑素mRNA的表達及電針的影響. 承德醫學院學報 2001, 18(4)267-271.
21.Zhan Zhuang Tian, Zhao Hong: Acupuncture Therapy for Menopausal and Perimenopausal Syndrome (Editors: Ying Xia, Xiaoding Cao, Gencheng Wu, Jieshi Cheng, Acupuncture therapy for neurological diseases: A neurobiological view). TSINGHUA and Springer; 1st Edition 2010
榮譽獎項
2005年作為主要完成人獲上海市科技進步二等獎一項,中國中西醫結合學會科學技術獎三等獎一項。