甄鑫

甄鑫，博士，副教授，2013年畢業於南方醫科大學生物醫學工程專業，美國加州大學聖地亞哥分校Moores 腫瘤中心CART 實驗室訪問學者（2011-2012），美國德州大學西南醫學中心腫瘤放射治療系訪問助理教授（2016-至今），主要研究方向為醫學圖像處理，自適應放射治療，腫瘤放射物理等。

基本介紹

• 中文名：甄鑫
• 國籍：中國
• 畢業院校：南方醫科大學

學習經歷

2000.9-2005.6 南方醫科大學，生物醫學工程，學士

2005.9-2008.6 南方醫科大學，生物醫學工程，碩士

2010.9-2013.6 南方醫科大學，生物醫學工程，博士

2011.7-2012.8美國加州大學聖地亞哥分校Moores 腫瘤中心CART 實驗室訪問學者

2016.2-2017.8美國德州大學西南醫學中心腫瘤放射治療系訪問助理教授

工作經歷

2008.7-2010.12 南方醫科大學生物醫學工程學院醫療儀器研究所，助教

2010.12-2014.12 南方醫科大學生物醫學工程學院醫療儀器研究所，講師

2014.12-至今 南方醫科大學生物醫學工程學院醫療儀器研究所，副教授

研究方向

醫學圖像處理，自適應放射治療，腫瘤放射物理，機器學習在放療中的套用研究等

主要獲獎情況

2012年，AAPM California Chapter Norm Baily Award 2012, best student paper.

2013年，獲中國人民解放軍醫療成果獎三等獎

2014年，獲美國近距離放射治療2014年會（American Brachytherapy Society 2014 Meeting）Top Four Abstract- Best in Physics

2017年，獲美國美國醫學物理學家協會（American Association of Physicists in Medicine，AAPM）2017年會Science Council Session論文獎

科研課題

1. 2017年，國家自然科學基金海外及港澳學者合作研究基金-基於深度學習的宮頸癌放療併發症預測模型研究（主持）

2.2015 年，廣東省自然科學基金面上項目—套用於宮頸癌自適應近距離放療的精確變形配準模型研究（主持）

3.2014 年，廣州市科技計畫項目-珠江科技新星專項—自適應近距離放療中治療分次間CT 圖像變形配準算法研究（主持）

4.2013 年，國家自然科學基金青年基金項目—自適應放療中CT 和信息缺失CBCT 圖像快速變形配準方法的研究（主持）

代表性論文

1. Zhen X, Chen J, Zhong Z, Hrycushko B, Zhou L, Jiang S, Albuquerque K, Gu X: Deep convolutional neural network with transfer learning for rectum toxicity prediction in cervical cancer radiotherapy: a feasibility study. Phys Med Biol 2017, 62(21):8246-8263.

2. Zhen X, Zhao B, Wang Z, Timmerman R, Spangler A, Kim N, Rahimi A, Gu X: Comprehensive target geometric errors and margin assessment in stereotactic partial breast irradiation. Radiation oncology 2017, 12(1):151.

3. Liao Y, Wang L, Xu X, Chen H, Chen J, Zhang G, Lei H, Wang R, Zhang S, Gu X, Zhen X, Zhou L: An anthropomorphic abdominal phantom for deformable image registration accuracy validation in adaptive radiation therapy. Med Phys 2017, 44(6):2369-2378.

4. Li X, Zhang Y, Shi Y, Wu S, Xiao Y, Gu X, Zhen X, Zhou L: Comprehensive evaluation of ten deformable image registration algorithms for contour propagation between CT and cone-beam CT images in adaptive head & neck radiotherapy. PloS one 2017, 12(4):e0175906.

5. Liao YL, Chen HB, Zhou LH, Zhen X: Construction of an anthropopathic abdominal phantom for accuracy validation of deformable image registration. Technology and health care : official journal of the European Society for Engineering and Medicine 2016, 24 Suppl 2:S717-723.

6. Li X, Zhang YY, Shi YH, Zhou LH, Zhen X: Evaluation of deformable image registration for contour propagation between CT and cone-beam CT images in adaptive head and neck radiotherapy. Technology and health care : official journal of the European Society for Engineering and Medicine 2016, 24 Suppl 2:S747-755.

7. Chen H, Zhong Z, Liao Y, Pompos A, Hrycushko B, Albuquerque K, Zhen X*, Zhou L, Gu X: A non-rigid point matching method with local topology preservation for accurate bladder dose summation in high dose rate cervical brachytherapy. Phys Med Biol 2016, 61(3):1217-1237.

8. Xiao, Y., L.H. Zhou*, and X. Zhen*, FISER: Feature Image Space Enhanced Random Walker Algorithm for Brain Tumor Segmentation in Multimodal MR Images. Journal of Medical Imaging and Health Informatics, 2015. 5(8): p. 1977-1981.

9. Zhen X, Chen H, Yan H, Zhou L, Mell LK, Yashar CM, Jiang S, Jia X, Gu X, Cervino L: A segmentation and point-matching enhanced efficient deformable image registration method for dose accumulation between HDR CT images. Phys Med Biol 2015, 60(7):2981-3002.

10. H. Chen, X. Zhen*, X. Gu, H. Yan, L. Cervino, Y. Xiao, L. Zhou*, "SPARSE: Seed Point Auto-Generation for Random Walks Segmentation Enhancement in medical inhomogeneous targets delineation of morphological MR and CT images," Journal of Applied Clinical Medical Physics 16, 387-402 (2015).

11. Yan H, Zhen X, Folkerts M, Li Y, Pan T, Cervino L, Jiang S B and Jia X 2014 A hybrid reconstruction algorithm for fast and accurate 4D cone-beam CT imaging Medical Physics 41 071903

12. Zhen X, Chen H, Yan H, Zhou L, Mell L, Yashar C M, Jiang S B, Jia X, Gu X and Cervino L 2014a A Deformable Image Registration Method for Dose Accumulation between HDR CT Images Brachytherapy 13 S15-S6

13. Zhen X, Pompoš A, Chen H, Yan H, Zhou L, Jiang S B and Gu X 2014 Towards Accurate OAR Dose Accumulation in Cervix Brachytherapy: Applying a Non-Rigid Point Matching Method for Bladder Deformation Brachytherapy 13 S26-S7

14. Li N, Zarepisheh M, Uribe-Sanchez A, Moore K, Tian Z, Zhen X, Graves Y J, Gautier Q, Mell L, Zhou L, Jia X and Jiang S 2013 Automatic treatment plan re-optimization for adaptive radiotherapy guided with the initial plan DVHs Phys Med Biol 58 8725-38

15. Zhen X, Yan H, Zhou L, Jia X and Jiang S B 2013 Deformable image registration of CT and truncated cone-beam CT for adaptive radiation therapy Physics in Medicine and Biology 58 7979-93

16. Zhen X, Yan H, Hu J, Zhou L, Jia X, Jiang S and Cervino L 2013 SU-E-J-86: A Deformable Image Registration Method for Dose Accumulation Between IMRT and HDR CT Images. AAPM) pp 000170-170

17. Yan H, Zhen X, Cervino L, Jiang S and Jia X 2013a WE-G-141-06: Progressive Cone Beam CT Dose Control in Image-Guided Radiation Therapy. AAPM) pp 000508-508

18. Yan H, Zhen X, Folkerts M, Pan T, Cervino L, Jiang S and Jia X 2013b TH-C-103-08: BEST IN PHYSICS (IMAGING) --- A Hybrid 4D Cone Beam CT Reconstruction Algorithm for Highly Under-Sampled Projections From the 1-Minute Cone Beam Scan. AAPM) pp 000543-543

19. Zhen X, Gu X, Yan H, Zhou L*, Jia X*, Jiang SB*: CT to cone-beam CT deformable registration with simultaneous intensity correction. Physics in Medicine and Biology 57(21):6807-6826, 2012.(SCI收錄, IF 2.829)

20. Yan H, Zhen X, Cerviño L, Jiang S B and Jia X 2013 Progressive cone beam CT dose control in image-guided radiation therapy Medical Physics 40 060701 (SCI收錄, IF 2.83)

21. Zhen X, Graves Y, Yan H, Zhou L*, Jia X*, Jiang S*: WE-E-213CD-07: Deformable Registration Between CT and Truncated CBCT for Adaptive Therapy Dose Calculation. AAPM 2012: 3961-3961, Charlotte, USA. 2012.7.29-8.2. (Oral presentation, SCI收錄)

22. Zhen X, Yan H, Gu X, Zhou L*, Jia X*, Jiang S*: WE-E-213CD-04: CT to Cone-Beam CT Deformable Registration With Simultaneous Intensity Correction. AAPM 2012: 3960-3960, Charlotte, USA. 2012.7.29-8.2. (Oral presentation, SCI收錄)

23. Graves Y, Zhen X, Kim G, Gautier Q, Tian Z, Cervino L, Lambrecht M, Jia X*, Jiang S*: SU-E-T-340: Estimation of the Delivered Fractional and Accumulative Patient Dose in IMRT and VMAT. AAPM 2012: 3782-3782, Charlotte, USA. 2012.7.29-8.2. (Oral presentation, SCI收錄)

24. Kearney V, Wang X, Gu X, Yan H, Zhen X, Jia X, Jiang S, Cervino L: SU-C-BRA-02: Evaluation of 2D DIR from CBCT to 4DCT Projections as a Tool for IGART. AAPM 2012: 3602-3603, Charlotte, USA. 2012.7.29-8.2. (Oral presentation, SCI收錄)

25. 周露, 甄鑫, 盧文婷, 竇建洪, 周凌宏*: 基於改進Demons算法的非剛性配準及其在腫瘤放療中的套用. 南方醫科大學學報 2012(01):40-45.

26. Zhen X, Zhou L*, Lu W, Zhang S: Deformable Registration for Re-Contouring and Phase Prediction in 4D CT. In: Biomedical Engineering and Computer Science (ICBECS), 2010 International Conference on: 1-4, Wuhan, China,2010.4.24-4.25. (EI收錄)

27. 甄鑫, 周凌宏*, 盧文婷, 張書旭, 周露: 改進Demons算法的驗證及其在4D-CT輪廓線推衍中的套用. 南方醫科大學學報 2010(12):2619-2624.

28. 甄鑫, 陳海斌, 肖陽, 胡潔, 周凌宏: HDR後裝治療CT圖像至IMRT CT圖像變形配準算法研究. 中華放射腫瘤學雜誌 2015, 24(2):209-212.

29. 甄鑫, 周凌宏: CT和信息缺失CBCT圖像變形配準方法研究. 國外電子測量技術 2014(06):61-65.

30. 甄鑫, 陳海斌, 肖陽, 胡潔, 周凌宏: 調強放療CT圖像至高劑量率後裝治療CT圖像變形配準算法研究. 中國輻射衛生 2014(04):293-297.