王魁,男,1988年4月出生,四川大學華西基礎醫學與法醫學院副研究員,碩士研究生導師。
基本介紹
- 中文名:王魁
- 國籍:中國
- 出生日期:1988年4月
- 畢業院校:四川大學
- 學位/學歷:博士
- 專業方向:腫瘤學
人物經歷
學術成果
- 代表性論文(*共同第一作者;#共同通訊作者)
- Wang K, Jiang J, Lei Y, Zhou S, Wei Y, Huang C. Targeting Metabolic-Redox Circuits for Cancer Therapy. Trends Biochem Sci. 2019;44(5):401-14. (IF: 16.89)
- Jiang J, Zhang L, Chen H, Lei Y, Zhang T, Wang Y, Jin P, Lan J, Zhou L, Huang Z, Li B, Liu Y, Gao W, Xie K, Zhou L, Nice EC, Peng Y, Cao Y, Wei Y, Wang K, Huang C. Regorafenib induces lethal autophagy arrest by stabilizing PSAT1 in glioblastoma. Autophagy. 2020;16(1):106-22. (IF: 11.06 共同通訊作者)
- Huang Z*, Zhou JK*, Wang K*, Chen H, Qin S, Liu J, Luo M, Chen Y, Jiang J, Zhou L, Zhu L, He J, Li J, Pu W, Gong Y, Li J, Ye Q, Dong D, Hu H, Zhou Z, Dai L, Wei Y, Huang C, Wei X, Peng Y. PDLIM1 inhibits tumor metastasis through activating Hippo signaling in hepatocellular carcinoma. Hepatology. 2019; doi: 10.1002/hep.30930. (IF: 14.97; 共同第一作者).
- Wang K, Liu R, Li J, Mao J, Lei Y, Wu J, Zeng J, Zhang T, Wu H, Chen L, Huang C, Wei Y. Quercetin induces protective autophagy in gastric cancer cells: involvement of Akt-mTOR- and hypoxia-induced factor 1α-mediated signaling. Autophagy. 2011;7(9):966-78. (IF: 11.06; 被引用248次)
- Wang K, Zhang T, Lei Y, Li X, Jiang J, Lan J, Liu Y, Chen H, Gao W, Xie N, Chen Q, Zhu X, Liu X, Xie K, Nice EC, Wu M, Huang C, Wei Y. Identification of ANXA2 (annexin A2) as a Specific Bleomycin Target to Induce Pulmonary Fibrosis by Impeding TFEB-mediated Autophagic Flux. Autophagy. 2018;14(2):269-82. (IF: 11.06)
- Lei Y*, Wang K*, Li X*, Li Y, Feng X, Zhou J, Zhang Z, Huang C, Zhang T. Cell-surface Translocation of Annexin A2 contributes to bleomycin-induced pulmonary fibrosis by mediating inflammatory response in mice. Clin Sci. 2019;133(7):789-804. (IF: 5.24; 共同第一作者)
- Wang K, Chen Y, Zhang P, Lin P, Xie N, Wu M. Protective Features of Autophagy in Pulmonary Infection and Inflammatory Diseases. Cells. 2019;8(2). pii: E123. (IF: 5.66)
- Wang K, Gao W, Dou Q, Chen H, Li Q, Nice EC, Huang C. Ivermectin induces PAK1-mediated cytostatic autophagy in breast cancer. Autophagy. 2016;12(12):2498-9. (IF: 11.06)
- Dou Q*, Chen HN*, Wang K*, Yuan K*, Lei Y, Li K, Lan J, Chen Y, Huang Z, Xie N, Zhang L, Xiang R, Nice EC, Wei Y, Huang C. Ivermectin Induces Cytostatic Autophagy by Blocking the PAK1/Akt Axis in Breast Cancer. Cancer Res. 2016;76(15):4457-69. (IF: 8.38; 共同第一作者)
- Wang K, Zhang T, Dong Q, Nice EC, Huang C, Wei Y. Redox homeostasis: the linchpin in stem cell self-renewal and differentiation. Cell Death Dis. 2013;14;4:e537.(IF: 5.96; 被引用199次)
- Lei Y*, Wang K*, Deng L*, Chen Y, Nice EC, Huang C. Redox Regulation of Inflammation: Old Elements, a New Story. Med Res Rev. 2015;35(2):306-40. (IF: 9.79; 共同第一作者)
- Jiang J*, Wang K*, Chen Y*, Chen H, Nice EC, Huang C. Redox regulation in tumor cell epithelial-mesenchymal transition: Molecular basis and therapeutic strategy. Signal Transduct Target Ther. 2017;2:e17036. (IF: 5.87,*共同第一作者)
社會任職
獲獎情況
- 第十三批四川省衛生健康委員會學術技術帶頭人後備人選(2019)
- 四川省科協青年人才托舉工程(2018)
- 四川大學青年科技學術帶頭人培育項目(2019)
- 四川大學學術新人獎(2018)
- 四川大學青年科技人才獎(2018)
- 四川大學好未來優秀學者獎(2019)