王斌貴，1963年1月生，理學博士，現任中國科學院海洋研究所研究員，博士生導師，兼任實驗海洋生物學重點實驗室副主任、中國藥學會海洋藥物專業委員會委員、Marine Drugs國際編委等。中國科學院“百人計畫”入選者。曾先後在日本、德國、美國等留學、合作研究。曾獲國務院“政府特殊津貼”、“新世紀百千萬人才工程”國家級人選、全國優秀科技工作者、中國科學院“優秀研究生導師”、青島市專業技術拔尖人才等榮譽稱號，入選中國科學院百人計畫、山東省泰山學者特聘教授等。
基本介紹
- 中文名：王斌貴
- 國籍：中國
- 出生日期：1963年1月
- 學位/學歷：理學博士
研究方向,科研項目,個人榮譽,研究課題,代表性論文,
研究方向
2002年入選中國科學院“百人計畫”，曾先後在日本、德國、美國等留學、合作研究。主要從事海洋天然藥物化學、海洋生物活性物質研究。以海洋生物（海洋動、植物和海洋微生物）為主要研究對象，以海洋天然產物化學、海洋天然藥物化學研究為基礎，以海洋生物中防治重要疾病創新藥物先導結構的發現與最佳化為主要研究方向。
科研項目
已發表論文100餘篇（其中SCI論文70餘篇），申請國家發明專利6項，參編專著3部。近年來主持完成中國科學院“百人計畫”項目、國家自然科學基金重點項目、中國科學院知識創新工程前沿領域項目等課題。課題組目前承擔國家自然科學基金重大國際合作項目、科技部“863計畫”項目、山東省科技發展計畫重點項目等課題的執行。
個人榮譽
曾獲中國科學院“百人計畫”（2003）、國家人事部“新世紀百千萬人才工程”（2007）、國務院“政府特殊津貼”（2008）、青島市“專業技術拔尖人才”（2008）及中國科學院“優秀研究生導師”（2008）等榮譽稱號。
研究課題
1.中國科學院“百人計畫”項目“海洋生物活性先導化合物的發現”（2003-2006）；
2.國家自然科學基金重點項目“松節藻科海洋紅藻若干重要屬、種的化學、生物活性與經典分類學基礎研究”（2005-2009）；
3.科技部“863計畫”目標導向課題“海洋共生菌活性物質的高效利用”（2007-2010）；
4.國家自然科學基金重大國際合作項目“海洋特殊環境中紅樹林植物內生真菌生物多樣性、活性成分及化學生態學意義”（2010-2012）；
代表性論文
1． Cui C M, Li X M, Li C S, Proksch P, Wang B G*, Cytoglobosins A–G, Seven New Cytochalasans from a Marine Derived Endophytic Fungus Chaetomium globosum QEN-14, Journal of Natural Products
2．Yan H J, Gao S S, Li C S, Li X M, Wang B G*, Chemical Constituents of a Marine-derived Endophytic Fungus Penicillium commune G2M, Molecules
3．Li C S, Li X M, Cui C M, Wang B G*,Brominated Metabolites from the Marine Red Alga Laurencia similis,Zeitschrift für Naturforschung
4． Wang B G*, Zhang W W, Duan X J, Li X M, In vitro antioxidative activities of extract and semi-purified fractions of the marine red alga Rhodomela confervoides (Rhodomelaceae). Food Chemistry
5． Li D L, Li X M, Wang B G*, Natural Anthraquinone Derivatives from a Marine Mangrove Plant-derived Endophytic Fungus Eurotium rubrum: Structural Elucidation and DPPH Radical-scavenging Activity. Journal of Microbiology and Biotechnology
6． Ji N Y, Li X M, Li K, Wang B G*, Halogenated Sesquiterpenes from the Marine Red Alga Laurencia saitoi (Rhodomelaceae), Helvetica Chimica Acta
7．Cui C M, Li X M, Li C S, Sun H F, Gao S S, Wang B G*, Benzodiazepine Alkaloids from Marine-Derived Endophytic Fungus Aspergillus ochraceus, Helvetica Chimica Acta
8．Liang Y, Li X M, Cui C M, Li C S, Wang B G*,A new rearranged chamigrane sesquiterpene from Laurencia okamurai, Chinese Chemical Letters
9．Gao S S, Li X M, Wang B G*, Perylene Derivatives Produced by Alternaria alternate, an Endophytic Fungus Isolated from Algal Species of Laurencia sp., Natural Product Communications
10．Li K, Li X M, Ji N Y, Gloer J B, Wang B G*,Urceolatin, a Structurally Unique Bromophenol from Polysiphonia urceolata, Organic Letters
11．Li K, Li X M, Ji N Y, Wang B G*, Bromophenols from the Marine Red Alga Polysiphonia urceolata (Rhodomelaceae) with DPPH Radical Scavenging Activity, Journal of Natural Product
12．Ji N Y, Li X M, Xie H, Ding J, Li K, Ding L P, Wang B G*, Highly Oxygenated Triterpenoids from the Marine Red Alga Laurencia mariannensis (Rhodomelaceae). Helvetica Chimica Acta
13．Li D L, Li X M, Li T G, Dang H Y, Wang B G*, Dioxopiperazine Alkaloids Produced by the Marine Mangrove Derived Endophytic Fungus Eurotium rubrum. Helvetica Chimica Acta
14．Ji N Y, Li X M, Li K, Ding L P, Gloer, J B, Wang B G*, Diterpenes, Sesquiterpenes, and a C15-Acetogenin from the Marine Red Alga Laurencia mariannensis, Journal of Natural Products
15．Li K, Li X M, Ji N Y, Wang B G*, Natural Bromophenols from the Marine Red Alga Polysiphonia urceolata (Rhodomelaceae): Structural Elucidation and DPPH Radical-scavenging Activity. Bioorganic & Medicinal Chemistry
16．Ji N Y, Li X M, Li K, Wang B G*, Laurendecumallenes A-B and Laurendecumenyns A-B, Halogenated Nonterpenoid C15-Acetogenin from the Marine Red Alga Laurencia decumbens, Journal of Natural Products,
17．Duan X J, Li X M, Wang B G*, Highly Brominated Mono- and Bis-phenols form the Marine Red Alga Symphyocladia latiuscula with Radical-scavenging Activity, Journal of Natural Products
18．Zhang Y, Li X M, Peter Proksch, Wang B G*, Ergosterimide, a New Natural Diels-Alder Adduct of a Steroid and Maleimide in the Fungus Aspergillus niger, Steroids
19．Wang S, Li X M, Teuscher F, Li D L, Diesel A, Ebel R, Proksch P, Wang B G*, Chaetopyranin, a Benzaldehyde Derivative and Other Related Metabolites from Chaetomium globosum,an Endophytic Fungus Derived from Marine Red Alga Polysiphonia urceolata. Journal of Natural Products
20．Duan X J, Zhang W W, Li X M, Wang B G*, Evaluation of Antioxidant Property of Extract and Fractions Obtained from a Red Alga, Polysiphonia urceolata, Food Chemistry
21. Wang B G*, Gloer J B, Ji N Y, Zhao J C, Halogenated Molecules of Rhodomelaceae Origin: Chemistry and Biology, Chemical Reviews, 2013, 113(5), 3632-3685.
22. Zhang Z, Miao L, Lv C, Sun H, Wei S, Wang B G*, Huang C G*, Jiao B H*, Wentilactone B Induces G2/M Phase Arrest and Apoptosis via the Ras/Raf/MAPK Signaling Pathway in Human Hepatoma SMMC-7721 Cells. Cell Death & Disease, 2013, 4, e657.
23. Lv C, Hong Y, Miao L, Li C S, Xu G M, Wei S, Wang B G*, Huang C G*, Jiao B H*, Wentilactone A as a Novel Potential Antitumor Agent Induces Apoptosis and G2/M Arrest of Human Lung Carcinoma Cells, and is Mediated by HRas-GTP Accumulation to Excessively Activate the Ras/Raf/ERK/p53-p21 Pathway. Cell Death & Disease, 2013, 4, e952.
24. Du F Y, Zhang P, Li X M, Li C S, Cui C M, Wang B G*, Cyclohexadepsipeptides of the Isaridin Class from the Marine-Derived Fungus Beauveria felina EN-135, Journal of Natural Products, 2014, 77(4), 1164−1169.
25. Meng L H, Li X M, Liu Y, Wang B G*, Penicibilaenes A and B, Sesquiterpenes with a Tricyclo[6.3.1.01,5]dodecane Skeleton from the Marine Isolate of Penicillium bilaiaeMA-267, Organic Letters, 2014, 16(23), 6052−6055.
26. Zhang P, Mándi A, Li X M, Du F Y, Wang J N, Li X, Kurtán T*, Wang B G*, Varioxepine A, a 3H-Oxepine-Containing Alkaloid with a New Oxa-Cage from the Marine Algal-Derived Endophytic Fungus Paecilomyces variotii, Organic Letters, 2014, 16(18), 4834−4837.
27. Zhao J C, Li, X M, Gloer J B, Wang B G*, First Total Syntheses and Antimicrobial Evaluation of Penicimonoterpene, a Marine-Derived Monoterpenoid, and Its Various Derivatives, Marine Drugs, 2014, 12(6), 3352-3370.
28. Meng L H, Liu Y, Li X M, Xu G M, Ji N Y*, Wang B G*, Citrifelins A and B, Citrinin Adducts with a Tetracyclic Framework from Cocultures of Marine-derived Isolates of Penicillium citrinum and Beauveria felina. Journal of Natural Products, 2015, 78(9), 2301−2305.
29. Li X D, Li X M, Li X, Xu G M, Liu Y, Wang B G*, Aspewentins D−H, 20-Nor-isopimarane Derivatives from the Deep Sea Sediment-Derived Fungus Aspergillus wentii SD-310. Journal of Natural Products, 2016, 79(5), 1347−1353.
30. Ji N Y*, Wang B G*, Mycochemistry of Marine Algicolous Fungi. Fungal Diversity, 2016, online published, doi:10.1007/s13225-016-0358-9.
