人物經歷
2008年取得德州大學休斯頓健康科學中心免疫學博士學位;
2008年~2013年於耶魯大學、康涅狄克大學從事博士後工作;
2012年~至今 美國IMSTEM Biotechnology Inc.公司副總裁,首席技術執行官;
2014年~至今 珠海橫琴愛姆斯坦生物科技有限公司首席技術官兼聯合創始人。
主要成就
愛姆斯坦CTO王小方主導的項目人胚幹細胞衍生的間充質乾細隨治療多發性硬化的研究榮獲康涅狄克州幹細胞研究基金113萬美元。
代表文章
· Xing Chang Fang Liu Xiaofang Wang Aiping Lin Hongyu Zhao Bing Su. The Kinases MEKK2 and MEKK3 Regulate Transforming Growth Factor-β-Mediated Helper T Cell Differentiation. Immunity. 2011;34(2):201-212.
· Dongyu Zhang Valeria Facchinetti Xiaofang Wang Qiaojia Huang Jun Qin Bing Su. Identification of MEKK2/3 serine phosphorylation site targeted by the Toll-like receptor and stress pathways. EMBO J. 2006;25(1):97-107.
· Jun Xu, Xiaofang Wang, Jiaye Chen, Shengbo Chen, Zhijun Li, Hongbin Liu, Yang Bai, Fachao Zhi. Embryonic stem cell-derived mesenchymal stem cells promote colon epithelial integrity and regeneration by elevating circulating IGF-1 in colitis mice. Theranostics. 2020;10(26):12204-12222.
· Xiaofang Wang Erin A. Kimbrel Kumiko Ijichi Stephen J. Crocker Robert Lanza Ren-He Xu . Human ESC-Derived MSCs Outperform Bone Marrow MSCs in the Treatment of an EAE Model of Multiple Sclerosis. Stem Cell Reports.2014;3(1):115-130.
·Dejin Zheng, Xiaofang Wang, Ren-He Xu. Concise Review: One Stone for Multiple Birds: Generating Universally Compatible Human Embryonic Stem Cells. Stem Cells. 2016;34(9):2269-2275.
· Xiaofang Wang, Adam S. Lazorchak, Li Song, Enqin Li, Zhenwu Zhang, Bin Jiang, Ren-He Xu. Immune modulatory mesenchymal stem cells derived from human embryonic stem cells through a trophoblast-like stage. Stem Cells. 2016;34(2):380-391.