王啟鳴，男，鄭州大學附屬腫瘤醫院/河南省腫瘤醫院內科副主任，呼吸內科三病區主任，主任醫師 ，腫瘤學博士，美國安德森癌症中心博士後，鄭州大學碩士生導師，河南省學術技術帶頭人，河南省優秀中青年衛生科技創新人才，河南省腫瘤醫院優秀拔尖人才 ，河南省醫學會醫療事故（醫療損害）技術鑑定專家庫成員。
基本介紹
- 中文名：王啟鳴
- 國籍：中國
- 職業：鄭州大學附屬腫瘤醫院/河南省腫瘤醫院內科副主任
- 性別：男
研究方向,出診信息,學術兼職,獲獎情況,著作譯作,相關論文,會議論文、講座：,承擔科研項目,
研究方向
出診信息
周三上午 ，周四下午
學術兼職
《Cancer》、《AnnalsofOncology》、《Biochimie》、《CancerMedicine》、《APMIS》、《MedicalScienceMonitor》等SCI期刊審稿人 ；
美國AACR會員；
河南省抗癌協會化療專業委員會，委員；
河南省抗癌協會肺癌專業委員會，委員；
河南省抗癌協會頭頸腫瘤專業委員會，委員；
河南省抗癌協會腫瘤流行病與病因專業委員會，委員；
獲獎情況
1.性激素及其受體與食管癌變的關係；河南省衛生廳科技進步二等獎；（第一完成人）
2.晚期非小細胞肺癌靶向治療優勢人群的篩選；河南省科技進步二等獎；（第三完成人）
著作譯作
1.《腫瘤分子靶向治療新進展》 ，2012年，科學出版社，副主編；
2.《整合miRNA腫瘤學基礎》，2013年，科學出版社，副主編。
相關論文
1. Qi YJ, Ward DG, Pang C, Wang QM, Wei W, Ma J, Zhang J, Lou Q, Shimwell NJ, Martin A, Wong N, Chao WX, Wang M, Ma YF, Johnson PJ. Proteomic profiling of N-linked glycoproteins identifies ConA-binding procathepsin D as a novel serum biomarker for hepatocellular carcinoma. Proteomics. 2014 Feb;14(2-3):186-95. doi: 10.1002/pmic.201300226.
2. Shen R, Liu H, Wen J, Liu Z, Wang LE, Wang Q, Tan D, Ajani JA, Wei Q. Genetic polymorphisms in the microRNA binding-sites of the thymidylate synthase gene predict risk and survival in gastric cancer. Mol Carcinog. 2014 Apr 23. doi: 10.1002/mc.22160. [Epub ahead of print]
3. Wen J, Liu H, Wang Q, Liu Z, Li Y, Xiong H, Xu T, Li P, Wang LE, Gomez DR, Mohan R, Komaki R, Liao Z, Wei Q. Genetic variants of the LIN28B gene predict severe radiation pneumonitis in patients with non-small cell lung cancer treated with definitive radiation therapy. Eur J Cancer. 2014 Apr 25. pii: S0959-8049(14)00251-2. doi: 10.1016/j.ejca.2014.03.008. [Epub ahead of print]
4. Wang Q, Liu H, Xiong H, Liu Z, Wang LE, Qian J, Muddasani R, Lu V, Tan D, Ajani JA, Wei Q. Polymorphisms in the microRNA binding-site in the stem cell marker gene CD133 modify susceptibility to and survival of gastric cancer. Mol Carcinog. 2013 Dec 2. doi: 10.1002/mc.22113. [Epub ahead of print]
5. Xiong H, Liao Z, Liu Z, Xu T, Wang Q, Liu H, Komaki R, Gomez D, Wang LE, Wei Q. ATM Polymorphisms Predict Severe Radiation Pneumonitis in Patients With Non-Small Cell Lung Cancer Treated With Definitive Radiation Therapy. Int J Radiat Oncol Biol Phys. 2012 Nov 12. doi:pii: S0360-3016(12)03602-4. 10.1016/j.ijrobp.2012.09.024
6. Qian J, Qu HQ, Yang L, Yin M, Wang Q, Gu S, Wu Q, Zhao X, Wu W, Wu J, Tan X, Chen W, Wang H, Wang J, Fan W, Chen H, Han B, Lu D, Wei Q, Jin L. Association Between CASP8 and CASP10 Polymorphisms and Toxicity Outcomes With Platinum-Based Chemotherapy in Chinese Patients With Non-Small Cell Lung Cancer. Oncologist. 2012;17(12):1551-61. doi: 10.1634/theoncologist.2011-0419. Epub 2012 Jul 27.
7. Zhang T, Zhao D, Wang Q, Yu X, Cui Y, Guo L, Lu SH. MicroRNA-1322 Regulates ECRG2 Allele Specifically and acts as a potential Biomarker in Patients with Esophageal Squamous Cell Carcinoma. Mol Carcinog. 2012 Feb 7. doi: 10.1002/mc.21880. [Epub ahead of print]. (SCI，IF 3.265)
8. Wang H, Zhang G, Li P, Yan X, Wang Q, Zhu H, Qi G, Fan Q, Ma Z. Differential efficacy of gefitinib across age groups in treatment of advanced lung adenocarcinoma. Pharmazie. 2012 Jan;67(1):80-5
9. Zhang T, Wang Q, Zhao D, Cui Y, Cao B, Guo L, Lu SH.The oncogenetic role of microRNA-31 as a potential biomarker in oesophageal squamous cell carcinoma. Clin Sci (Lond). 2011, 121(10):437-47. (co-first author) (SCI，IF 4.613)
10.Wang QM, Wang S, Wang HJ, Li P, Ma ZY. MicroRNAs: novel biomarkers for lung cancer diagnosis, prediction and treatment. Exp Biol Med (Maywood). 16 February 2012, 10.1258/ebm.2011.011192. (SCI，IF 3.0)
11. Wang QM, Qi YJ, Jiang Q, Ma YF, Wang LD. Relevance of serum estradiol and estrogen receptor beta expression in high-incidence area for esophageal squamous cell carcinoma. Med Oncol. 2011; 28(1):188-93.(SCI，IF 2.210)
12. Wang QM, Yuan L, Qi YJ, Ma ZY, Wang LD.Estrogen analogues: promising target for prevention and treatment of esophageal squamous cell carcinoma in high risk areas. Med Sci Monit. 2010; 16(7):HY19-22. (SCI，IF 1.699)
13.Wang Q, Wang H, Li P, Zhu H, He C, Wei B, Ma J, Ma Z. Erlotinib-based Perioperative Adjuvant Therapy for A Case of Unresectable Stage IIIA(N2) Non-Small Cell Lung Cancer. AM J MED SCI, 2010; 340(4):321-5. (SCI，IF 1.257)
14.Yan X, Zhu H, Wang H, Wang Q, Li P, Ma Z. The role of adjuvant chemotherapy in operable non-small cell lung cancer. Zhongguo Fei Ai Za Zhi. 2011;14(3):281-5. Chinese.
15.Li P, Wang Q, Wang H, Ma Z. Research progresses of albumin-bound paclitaxel in the treatment of non-small cell lung cancer. Zhongguo Fei Ai Za Zhi. 2010;13(7):748-52. doi: 10.3779/j.issn.1009-3419.2010.07.16. Chinese.
16.Song ZB, Gao SS, Yi XN, Li YJ, Wang QM, Zhuang ZH, Wang LD. Expression of MUC1 in esophageal squamous-cell carcinoma and its relationship with prognosis of patients from Linzhou city, a high incidence area of northern China. World J Gastroenterol. 2003 Mar;9(3):404-7.
17.Ji Xue Li, L. D. Wang, Shu Zheng, Bin Liu, Ruifeng Guo, Qiming Wang, Zongmin Fan, Hong Chen, Zehao Zhuang, Jiye An, Chao Sun, Shegan Gao, Jilin Li, Zibo Song, Xinwei He, Yanjie Li, Shanshan Gao, Huaqin Guo, Dongling Xie, Xinna Yi, Zhonghua Ding and Chung S. Yang. Analysis on color endoscopic mass survey (iodine staining) and surgically resected esophageal specimen on the subjects at high-incidence area for esophageal cancer in Henan. Proc. Am. Assoc. Cancer Res, 2003, 44:
18.Z B Song, S S Gao, X N Yi, Y J Li, Q M Wang, Z H Zhuang, L. D. Wang. Expression of MUC1 in esophageal squamous-cell carcinoma and its relationship with prognosis of patients from Linzhou city, a high incidence area of northernChina. World J Gastroenterol, 2003; 9(3):404-407
會議論文、講座：
1.Wang QM. Functional Polymorphisms in Cancer Stem Cell Marker Gene CD133 Predict Local Recurrence and Distant Metastasis in Non-Small Cell Lung Cancer Patients Treated With Definitive Radiotherapy. 2014 World Cancer Congress. Melbourne,Australia, 3 - 6 December 2014.
2.Wang QM. Functional Polymorphisms in Cancer Stem Cell Marker Gene CD133 Predict Local Recurrence and Distant Metastasis in Non-Small Cell Lung Cancer Patients Treated With Definitive Radiotherapy. Journal of Thoracic Oncology (2014) 9 (Supplement 9): S7-S52. 10.1097/JTO.0000000000000131. 26-29 March 2014. The European Lung Cancer Conference 2014, Geneva,Switzerland.
3.Wang QM. Functional Polymorphisms in Cancer Stem Cell Marker Gene CD133 Predict Local Recurrence and Distant Metastasis in Non-Small Cell Lung Cancer Patients Treated With Definitive Radiotherapy. May 2-4, 2014. The 11th international conference of the Asian Clinical Oncology Society, Taipei,Taiwan
4.王啟鳴，李鵬，Hongliang Liu，熊慧華，錢吉，Daniel Gomez，Zhensheng Liu，Li-E Wang Zhongxing Liao，Qingyi Wei. CD133的miRNA結合位點單核苷酸多態性可預測根治性放療的非小細胞肺癌患者的局部復發和遠處轉移. 第八屆中國腫瘤內科大會暨第三屆中國腫瘤醫師大會,2014.7.2-6, 北京
5.Wang QM. SNP in CD133 Predict Recurrence and Metastasis in NSCLC With Radiotherapy. The 40th Annual Meeting of Korean Cancer Association (KCA), June 19-20, Seoul,Korea
6.王啟鳴. 腫瘤幹細胞標誌基因CD133的功能位點單核苷酸多態性可預測接受根治性放療的非小細胞肺癌患者的局部復發和遠處轉移. 第十七屆全國臨床腫瘤學大會暨2014年CSCO學術年會, 2014，9.17-21，廈門
7.王啟鳴. Functional Polymorphisms in Cancer Stem Cell Marker Gene CD133 Predict Local Recurrence and Distant Metastasis in Non-Small Cell Lung Cancer Patients Treated With Definitive Radiotherapy. 中華醫學會第八屆全國腫瘤中青年學術會議.2014,11,13 -15,廈門. 優秀論文
8.Wang QM. Functional Polymorphisms in Cancer Stem Cell Marker Gene CD133 Predict Local Recurrence and Distant Metastasis in Non-Small Cell Lung Cancer Patients Treated With Definitive Radiotherapy. 2013.10. Annual Meeting of 51st The Japan Society of Clinical Oncology (JSCO)，Kyoto, Japan
9.Wang QM. Polymorphisms in the microRNA binding-site in the stem cell marker gene CD133 modify susceptibility to and survival of gastric cancer. 2013.11. The 22nd Asia Pacific Cancer Conference (APCC), Tianjin,China
10.Wang QM. Functional Polymorphisms in Cancer Stem Cell Marker Gene CD133 Predict Local Recurrence and Distant Metastasis in Non-Small Cell Lung Cancer Patients Treated With Definitive Radiotherapy. 中華醫學會腫瘤學分會2013年學術年會. 北京. 大會宣讀. 優秀論文獎
11.Wang QM. Polymorphisms in the microRNA binding-site in the stem cell marker gene CD133 modify susceptibility to and survival of gastric cancer. 2013全國臨床腫瘤學年會(CSCO),廈門, 大會宣讀
12.王啟鳴. 腫瘤幹細胞標誌基因CD133的功能位點單核苷酸多態性可預測接受根治性放療的非小細胞肺癌患者的局部復發和遠處轉移. 《第13屆全國肺癌學術大會論文彙編》2013年，2013.09.9-10,長春
13.Wang QM, Liu HL, Wang Li-E, Amos CI, Spitz MR, Wei QY. Functional polymorphisms in the stem-cell related pathway affect susceptibility to non-small cell lung cancer: a finding from Texas lung cancer genome-wide association study. 2012 AACR, Chicago,USA
承擔科研項目
1.2014年，河南省省級科研院所預研項目，肺癌幹細胞標誌基因的miRNA結合位點SNP對肺癌幹細胞乾性的調控作用，經費5萬，項目負責人；
2.2013年，優秀河南省衛生科技創新型人才工程，肺癌血清診斷、預後、預測microRNA的篩選，經費5萬，項目負責人；
3.2013年，留學人員科技活動項目擇優資助經費項目，肺癌幹細胞標誌基因microRNA結合位點SNP的篩選與功能研究，經費3萬，項目負責人；
4.2012年，國家自然科學基金面上項目，肺癌幹細胞標誌基因microRNA結合位點SNP的篩選與功能研究，經費65萬，項目負責人；
5.2011年，河南省科技廳基礎與前沿，肺癌血清診斷、預後、預測microRNA的篩選，經費5萬，項目負責人；
6.2011年，河南省衛生廳重點課題，肺癌血清microRNA指紋庫的建立，經費5萬，項目負責人；
7.2010年，河南省衛生科技創新人才，經費4.5萬，項目負責人；
8.2010年，河南省醫學重點學科臨床專科學術帶頭人培養及高新技術引進項目，EGFR分子檢測對非小細胞肺癌EGFR-TKIs靶向藥物療效預測和耐藥逆轉的作用，經費10.9萬，項目負責人。
