王公軻,男,1978年生,河南南陽人,河南師範大學,博士,副教授,碩士研究生導師。
基本介紹
- 中文名:王公軻
- 外文名:Gongke Wang
- 國籍:中國
- 民族:漢族
- 出生地:河南南陽
- 出生日期:1978.10
- 職業:高校教師
- 畢業院校:河南師範大學
- 主要成就:2012年在日本獲得亞洲青年科學獎
2013年獲得國家自然科學基金資助
2017年獲得河南省高校科技創新團隊支持計畫 - 代表作品:國家自然科學基金項目:納米界面蛋白質分子作用機制研究
- 學歷:博士研究生
人物介紹,研究領域,科研項目,主要論文,
人物介紹
2001年6月畢業於河南師範大學化學專業,獲理學學士學位;2007年6月畢業於河南師範大學物理化學專業,獲理學碩士學位,導師:盧雁教授;2012年6月畢業於河南師範大學物理化學專業,獲理學博士學位,導師:盧雁教授;2016年開始在河南師範大學物理與材料科學學院從事博士後研究,合作導師:劉玉芳教授。2007年7月至今在河南師範大學化學化工學院從事教學科研工作。主要從事仿生智慧型納米界面自組裝,納米生物感測器構建和運用,以及配體與生物大分子作用機制等方面的研究。2012年在日本近畿大學舉行的第15屆國際熱分析與量熱學術會議上作邀請報告並獲得亞洲青年科學獎。2015年獲得河南師範大學青年五四獎章,2016年入選新鄉市創新人才支持計畫,2017年獲得河南省高等學校科技創新團隊支持計畫。近年來在Langmuir, Biosensors and Bioelectronics, Sensors and Actuators B: Chemical, Colloids and Surfaces B等國際著名的SCI源期刊發表論文30餘篇,論文被引用300餘次。現為國際期刊《Biosensors and Bioelectronics》、《Spectrochimica Acta A》、《Journal of Fluorescence》等的特約審稿人。
研究領域
1.生物大分子的識別以及與配體相互作用機制研究
2.仿生智慧型納米界面自組裝
3.基於納米材料的生物感測器的自組裝機制及套用研究
科研項目
- 國家自然科學基金項目:納米界面蛋白質分子作用機制研究
- 河南省高等學校科技創新團隊支持計畫:生物納米界面自組裝及套用研究
- 中國博士後科學基金:尺寸調控的納米金與蛋白質相互作用研究
- 河南省科學技術研究重點項目:納米金生物感測器的構建及對重金屬離子的分析套用研究
- 新鄉市科技創新人才計畫:納米粒子表面化學調控蛋白暈形成機制研究
- 新鄉市重點科技攻關計畫:納米生物感測器自組裝及對重金屬離子的分析套用研究
主要論文
- Gongke Wang*, Huimin Hou, Shuangli Wang, Changling Yan, Yufang Liu*. Exploring the interaction of silver nanoparticles with lysozyme: binding behaviors and kinetics. Colloids and Surfaces B: Biointerfaces, 2017, 157: 138–1451.
- Gongke Wang*, Huimin Hou, Ye Chen, Changling Yan, Guangyue Bai, Yan Lu. Exploration of Interactions between Decyl-β-D-glucopyranoside and Bovine Serum Albumin in Aqueous Solution. RSC Advances, 2016, 6: 19700–19706.
- Gongke Wang*, Xingbing Liu, Changling Yan, Guangyue Bai, Yan Lu. Probing the Binding of Trypsin to Glutathione-stabilized Gold Nanoparticles in Aqueous Solution. Colloids and Surfaces B: Biointerfaces, 2015, 135: 261–266.
- Gongke Wang*, Yanfang Lu, Changling Yan, Yan Lu. DNA-Functionalization Gold Nanoparticles based Fluorescence sensor for sensitive detection of Hg in aqueous solution. Sensors and Actuators B: Chemical, 2015, 211: 1–6.
- Gongke Wang, Ye Chen, Changling Yan, Yan Lu*. Study on the interaction between gold nanoparticles and papain by spectroscopic methods. Journal of Luminescence, 2015, 157: 229–234.
- Gongke Wang, Changling Yan, Yan Lu*. Exploring DNA binding properties and biological activities of dihydropyrimidinones derivatives. Colloids and Surfaces B: Biointerfaces. 2013, 106, 28– 36.
- Gongke Wang, Hongwei Wu, Dongchao Wang, Changling Yan, Yan Lu*. Exploring the binding mechanism of phosphoramidate derivative with DNA: Spectroscopy, calorimetry and modeling. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy. 2013, 104, 492–496.
- Gongke Wang, Xiangrong Li, Yaping Gou, Yuhan Chen, Changling Yan, Yan Lu*. DNA binding properties and biological evaluation of dihydropyrimidinones derivatives as potential antitumor agents. Spectrochimica Acta A: Molecular and Biomolecular Spectroscopy, 2013, 114: 214-219.
- Gongke Wang, Changling Yan, Dongchao Wang, Yan Lu*. Specific binding of a dihydropyrimidinone derivative with DNA: Spectroscopic, calorimetric and modeling investigations. Journal of Luminescence, 2012, 132: 1656–1662.
- Gongke Wang, Xiang Li, Xuelian Ding, Dongchao Wang, Changling Yan, Yan Lu*. Exploring the mechanism of interaction between 5-(Ethoxycarbonyl)-6-methyl-4-(4-methoxyphenyl)-3,4-dihydropyrimidin-2(1H)-one and human serum albumin: spectroscopic, calorimetric and molecular modeling studies. Journal of Pharmaceutical and Biomedical Analysis, 2011, 55: 1223–1226.
- Gongke Wang, Dongchao Wang, Xiang Li,Yan Lu*. Exploring the binding mechanism of dihydropyrimidinones to human serum albumin: Spectroscopic and molecular modeling techniques. Colloids and Surfaces B: Biointerfaces, 2011, 84: 272–279.
- Gongke Wang, Lixia Wang, Xiaoxiao Hao, Wen Tang, Yunlai Wang, Yan Lu*. Binding of quercetin to Lysozyme as probed by spectroscopic analysis and molecular simulation. Journal of Fluorescence, 2011, 21: 1879–1886.
- Xiangrong Li, Gongke Wang, Dejun Chen, Yan Lu*. β-Carotene and astaxanthin with human and bovine serum albumins. Food Chemistry, 2015, 179: 213–221.
- Xiangrong Li, Gongke Wang, Dejun Chen, Yan Lu*. Binding of ascorbic acid and α-tocopherol to bovine serum albumin: A comparative study. Molecular Biosystems, 2014, 10: 326–337.
- Xiangrong Li, Gongke Wang, Dejun Chen, Yan Lu*. Interaction of procyanidin B3 with bovine serum albumin. RSC Advances, 2014, 4: 7301–7312.
- Xiang Li, GongKe Wang, Xuelian Ding, Yuhan Chen, Yaping Gou, Yan Lu*. A “turn-on” fluorescent sensor for Pb based on graphene oxide and G-quadruplex DNA. Physical Chemistry Chemical Physics, 2013, 15: 12800–12804.
- Yan Lu*, Gong-Ke Wang, Juan Lv, Gui-Sheng Zhang, Qing-Feng Liu. Study on the Interaction of an Anthracycline Disaccharide with DNA by Spectroscopic Techniques and Molecular Modeling. Journal of Fluorescence, 2011, 21: 409–414.
- Yan Lu*, Gongke Wang, Wen Tang, Xiaoxiao Hao, Meihua Xu, Xiang Li. Study on the interaction of amino phosphine ester derivatives with DNA by spectroscopy, modeling and calorimetry. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2011, 82: 247–252.