湯亞東,女,博士,副教授,碩士生導師,2017年2月以“青年百人計畫”A層次引進到廣東工業大學製藥工程系工作。在微納製造、生物材料、微流控晶片技術等多學科交叉領域具有多年的研究經驗,目前的研究主要集中在微納加工生物材料和微流控技術在藥物緩釋、幹細胞與組織工程、藥物評價等方面的套用。先後主持或參與中歐國際合作項目、法國國家研究署基金、國家自然科學基金等多項國家級、省市級和校級科研項目。近年來已在Nanoscale、Desalination、J.Mat.Chem.B、Scientific Reports、Microfluidics and Nanofluidics等國際期刊發表SCI論文二十餘篇(其中第一作者或通訊作者發表SCI論文11篇),並有包括歐盟專利在內的多項國內外發明專利授權。
基本介紹
- 中文名:湯亞東
- 國籍:中國
- 職業:教師
- 畢業院校:巴黎高等師範學院&巴黎第六大學
- 學位/學歷:博士
- 專業方向:物理化學與分析化學
教育背景,工作經歷,學術成果,科研項目,主要論文,授權專利,教學活動,
教育背景
2013.04-2016.02,巴黎高等師範學院&巴黎第六大學,物理化學與分析化學,博士,導師:Yong Chen教授(博士學位論文獲法國教育部最高評價“Tres Honorable”)
2009.09-2012.07,西安交通大學,化學工程,碩士,導師:李娜教授
2005.09-2009.07,西安工業大學,高分子材料與工程,學士
工作經歷
2017.02 至今,廣東工業大學“青年百人計畫A類”,製藥工程系,副教授
2016.02-2017.01,巴黎高等師範學院化學系,博士後,導師:Yong Chen教授
2015.05-2015.08,京都大學iCeMS研究生,短期訪問
2014.06-2014.07,北京大學定量生物學中心,短期訪問
學術成果
科研項目
(1) 國家自然科學基金青年項目,“基於hiPSC和單層納米纖維基片技術構建仿生心臟晶片用於藥物心臟毒性多角度評價”,81801830,主持,21萬元,2019.01-2021.12
(2) 江門市創新團隊項目,“建立人類重大疾病實驗小型豬模型及幹細胞臨床前療效和安全評價體系”,2017TD02,核心成員,600萬,2018.04-2021.04
(3) 廣東工業大學青年百人科研啟動基金,“生物材料與生物晶片”,主持,20萬,2017年2月至2022年2月
(4) 法國國家研究署基金(ANR),”Pillarcell”,ANR-13-NANO-0011-01,2014/01-2017/07,635,482 歐元,已結題,參與
(5) 中歐國際合作項目,”Neuroscaffolds”,No. 604263,2013/07-2016/06,2,321,776歐元,已結題,參與
(6) 法國國家研究署基金(ANR),”CardiacPatch”,ANR-12-RPIB-0015,2013/01-2015/12,888,722 歐元,已結題,參與
主要論文
[1]Yadong Tang*,Xingzi Lan, Honey loaded alginate/PVA nanofibrous membrane as potential bioactive wound dressing [J].Carbohydrate Polymers, 2019, 219: 113–120.
[2]Yadong Tang*, Ying Zhou, Xingzi Lan, Dongchao Huang, Tingting Luo, Junjie Ji, Zihui Mafang, Xiaomin Miao, Han Wang, and Wenlong Wang*. Electrospun Gelatin Nanofibers Encapsulated with Peppermint and Chamomile Essential Oils as Potential Edible Packaging [J].Journal of Agricultrual and Food Chemistry, 2019, 67: 2227−2234. (封面論文)
[3] Feng Liang, Han Wang, YaJu Lin, Ying Zhou, Zhifeng Wang, Xindu Chen, Nian Cai, Fanwen Yang, Peixuan Wu, Yunbo He,Yadong Tang*. Near-field melt electrospinning of poly(ε-caprolactone) (PCL) microline array for cell alignment study [J].Materials Research Express, 2019, 6, 015401.
[4] Jun Zeng, Han Wang, Yaru Lin, Jiarong Zhang, Xin Chen, Xindu Chen, Zhifeng Wang, Nian Cai,Yadong Tang*, Peixuan Wu*. Fabrication of microfluidic channels based on melt-electrospinning direct writing.Microfluidics and Nanofluidics, 2018, 22: 23.
[5]Yadong Tang, Boxin Huang, Yuqin Dong, Wenlong Wang, Xi Zheng, Wei Zhou, Kun Zhang & Zhiyun Du*. Three-dimensional prostate tumor model based on a hyaluronic acid-alginate hydrogel for evaluation of anti-cancer drug efficacy[J],Journal of Biomaterials Science, Polymer Edition, 2017, 28(14):1603-1616.
[6]Yadong Tang, Francesco Paolo Ulloa Severino, Federico Iseppon, Vincent Torre*, Yong Chen*. Patch method for culture of primary hippocampal neurons[J].Microelectronic Engineering, 2017, 175: 61-66.
[7]Yadong Tang, Li Liu, Junjun Li, Leqian Yu, Li Wang, Jian Shi and Yong Chen*. Induction and differentiation of human induced pluripotent stem cells into functional cardiomyocytes on a compartmented monolayer of gelatin nanofibers [J].Nanoscale, 2016, 8(30): 14530-14540.
[8]Yadong Tang, Li Liu, Junjun Li, Leqian Yu, Francesco Paolo Ulloa Severino, Li Wang, Jian Shi, Xiaolong Tu, Vincent Torre and Yong Chen*. Effective motor neuron differentiation of human induced pluripotent stem cells on a patch made of crosslinked monolayer gelatin nanofibers [J].Journal of Materials Chemistry B, 2016, 4, 3305-3312.
[9]Yadong Tang, Jianmiao Liu, Yong Chen*. Agarose multi-wells for tumor spheroid formation and anti-cancer drug test [J].Microelectronic Engineering, 2016, 158: 41-45.
[10]Yadong Tang, Jian Shi, Sisi Li, Li Wang, Yvon E. Cayre & Yong Chen*. Microfluidic device with integrated microfilter of conical-shaped holes for high efficiency and high purity capture of circulating tumor cells [J].Scientific reports, 2014, 4.
[11]Yadong Tang, Na Li*, Anjun Liu, et al. Effect of spinning conditions on the structure and performance of hydrophobic PVDF hollow fiber membranes for membrane distillation [J].Desalination, 2012, 287: 326-339.
[12] Bin Wang, Li Wang,Yadong Tang, Jian Shi, Jin Wei, Xiaolong Tu, YongChen*. Fabrication of spaced monolayers of electrospun nanofibers for three-dimensional cell infiltration and proliferation[J].Microelectronic Engineering, 2018, 198: 73-77.
[13] Penghui Li,Yonglian Li,Hong Jiang,Yuting Xu, Xiaoying Liu, Biao Che, Jian Tang, Guangrong Liu,Yadong Tang, Wei Zhou, Langyue Zhang, Changzhi Dong, Huixiong Chen, Kun Zhang, Zhiyun Du*. Glabridin, an isoflavan from licorice root, ameliorates imiquimod-induced psoriasis-like inflammation of BALB/c mice [J].International immunopharmacology, 2018, 59, 243-251.
[14] Xiaolong Tu, Jin Wei, Bin Wang, Jian Shi,Yadong Tang, Yong Chen*. Patterned parylene C for cell adhesion, spreading and alignment studies [J].Microelectronic Engineering, 2017, 175: 56-60.
[15] Bin Wang, Jian Shi, Jin Wei, Li Wang, Xiaolong Tu,Yadong Tang, Yong Chen*. Fabrication of elastomer pillar arrays with height gradient for cell culture studies[J].Microelectronic Engineering, 2017, 175: 50-55.
[16] Jin Wei, Jian Shi, Bin Wang,Yadong Tanget al. Fabrication of Adjacent Micropillar Arrays with Different Heights for Cell Studies [J].Microelectronic Engineering, 2016, 158: 22-25.
[17] Xiaolong Tu,Lina Wang,Wei Jin,Bin Wang,Yadong Tang,Jian Shi,Zhijun,Zhang,Yong Chen*. 3D printed PEGDA microstructures for gelatin scaffold integration and neuron differentiation [J].Microelectronic Engineering, 2016, 158: 30-34.
授權專利
(1)Yadong Tang; Li Wang; Jian Shi; Yong Chen, Cell culture device, 2016.07.08, 歐洲, PCT/EP2016/066366
(2)湯亞東; 石劍; 李思思; 汪莉; 陳勇, 一種稀有細胞檢測晶片及其套用, 2014.07.23, 中國, CN 201410123388.1
(3) 陳勇;湯亞東; 石劍, 稀有細胞過濾器及其套用, 2014.06.25, 中國, CN201410109918
(4) 陳勇; 石劍;湯亞東; 張正濤; 曹一平, 一種旋轉式三維曝光裝置, 2013.11.14,中國, CN201320715430.2
教學活動
主要從事製藥工程相關的專業課程,如《專業英語》、《文獻檢索與論文撰寫》等課程的理論教學及實踐教學。