基本介紹
- 中文名：沈薇
- 國籍：中國
- 性別：女
- 職稱：教授
人物經歷,研究方向,課程教學,主要貢獻,科研項目,論文著作,獲獎記錄,
人物經歷
理學學士, 2007.08～2011.06，浙江大學（化學專業）
2016.07~，江蘇科技大學工作
研究方向
（1）微RNA靈敏分析檢測
（2）納米材料合成及分析套用
（3）DNA單核苷酸多態性分析檢測
（4）文物保護與文物分析檢測
課程教學
（1）化學工藝（碩士研究生）
（2）儀器分析（本科生）
（3）現代儀器分析（碩士研究生，雙語）
（4）Modern Analysis and Testing Technology（留學碩士研究生，全英文）
（5）分析化學（本科生）
主要貢獻
科研項目
（1）基於等溫循環信號放大的多通路同時檢測多種微RNA的分析方法，國家自然科學基金青年基金。（主持）
（2）靶向釕配合物功能化金納米粒子複合體系的構建及其螢光成像研究，國家自然科學基金面上項目。（參與）
（3）基於信號放大的高效檢測多種疾病相關微RNA的分析檢測，江蘇科技大學引進人才啟動基金。（主持）
（4）Ultrasensitive biosensors, A*STAR-ANR 。（參與）
（5）Developing new microfluidic chambers for cancer cell screening， A*STAR-ANR。（參與）
（6）Ultrasensitive and label-free assays，A*STAR-ANR。（參與）
（7）仿細胞結構水滑石材料的合成及其對肽類激素的萃取性能研究，國家自然科學基金青年基金。（參與）
（8）江蘇省“雙創計畫”。（主持）
（9）江蘇省“六大人才高峰”高層次人才項目。（主持）
（10） 江蘇科技大學“青年學者計畫”第二層次。（主持）
論文著作
[1] W. Shen, H. Deng, Z. Gao, Gold nanoparticle-enabled real-time ligation chain reaction for ultrasensitive detection of DNA, J. Am. Chem. Soc. 134 (2012) 14678-14681.
[2] W. Shen, H. Deng, Y. Ren, Z. Gao, A label-free microRNA biosensor based on DNAzyme-catalyzed and microRNA-guided formation of a thin insulating polymer film, Biosens. Bioelectron. 44 (2013) 171-176.
[3] W. Shen, H. Deng, Y. Ren, Z. Gao, An electronic sensor array for label-free detection of single-nucleotide polymorphisms, Biosens. Bioelectron. 43 (2013) 165-172.
[4] W. Shen, Z. Gao, Quantum dots and duplex-specific nuclease enabled ultrasensitive detection and serotyping of Dengue viruses in one step in a single tube, Biosens. Bioelectron. 65 (2015) 327-332.
[5] W. Shen, H. Deng, A.K.L. Teo, Z. Gao, Colorimetric detection of single-nucleotide polymorphisms with a real-time PCR-like sensitivity, Chem. Commun. 48 (2012) 10225-10227.
[6] W. Shen, H. Deng, Y. Ren, Z. Gao, A real-time colorimetric assay for label-free detection of microRNAs down to sub-femtomolar levels, Chem. Commun. 49 (2013) 4959-4961.
[7] W. Shen, C.L. Lim, Z. Gao, A ferrofluid-based homogeneous assay for highly sensitive and selective detection of single-nucleotide polymorphisms, Chem. Commun. 49 (2013) 8114-8116.
[8] W. Shen, H. Deng, A.K.L. Teo, Z. Gao, An electrodeposited redox polymer-laccase composite film for highly efficient four-electron oxygen reduction, J. Power Sources 226 (2013) 27-32.
[9] W. Shen, Y. Tian, T. Ran, Z. Gao, Genotyping and quantification techniques for single-nucleotide polymorphisms, TrAC, Trends Anal. Chem. 69 (2015) 1-13.
[10] W. Shen, K.H. Yeo, Z. Gao, A simple and highly sensitive fluorescence assay for microRNAs, Analyst 140 (2015) 1932-1938.
[11] W. Shen, H. Deng, Z. Gao, Synthesis of polyaniline via DNAzyme-catalyzed polymerization of aniline, RSC Adv. 4 (2014) 53257-53264.
[12] W. Shen, H. Deng, Z. Gao, Synthesis and anticancer properties of a novel bis-intercalator, Anti-Cancer Agents Med. Chem. 13 (2013) 632-638.
[13] S.Y. Lim, W. Shen, Z. Gao, Carbon quantum dots and their applications, Chem. Soc. Rev. 44 (2015) 362-381.
[14] H. Deng, W. Shen, Y. Ren, Z. Gao, A highly sensitive and selective homogenous assay for profiling microRNA expression, Biosens. Bioelectron. 54 (2014) 650-655.
[15] H. Deng, W. Shen, Y. Ren, Z. Gao, A highly sensitive microRNA biosensor based on hybridized microRNA-guided deposition of polyaniline, Biosens. Bioelectron. 60 (2014) 195-200.
[16] H. Deng, W. Shen, Z. Gao, Colorimetric detection of single nucleotide polymorphisms in the presence of 103-fold excess of a wild-type gene, Biosens. Bioelectron. 68 (2015) 310-315.
[17] Z. Gao, W. Shen, H. Deng, Y. Ren, Detection of single-nucleotide polymorphisms based on the formation of an electron-transfer impeding layer on an electrode surface, Chem. Commun. 49 (2013) 370-372.
[18] H. Deng, W. Shen, Z. Gao, Synthesis of water-soluble and cross-linkable ferrocenyl redox polymers for uses as mediators in biosensors, Sens. Actuators, B 168 (2012) 238-242.
[19] H. Deng, Y. Ren, W. Shen, Z. Gao, An ultrasensitive homogeneous chemiluminescent assay for microRNAs, Chem. Commun. 49 (2013) 9401-9403.
[20] Y. Ren, H. Deng, W. Shen, Z. Gao, A Highly Sensitive and Selective Electrochemical Biosensor for Direct Detection of MicroRNAs in Serum, Anal. Chem. 85 (2013) 4784-4789.
[21] Z. Gao, H. Deng, W. Shen, Y. Ren, A Label-Free Biosensor for Electrochemical Detection of Femtomolar MicroRNAs, Anal. Chem. 85 (2013) 1624-1630.
[22] Y. Yu, Y. Ren, W. Shen, H. Deng, Z. Gao, Applications of metal-organic frameworks as stationary phases in chromatography, TrAC, Trends Anal. Chem. 50 (2013) 33-41.
[23] H. Deng, W. Shen, Y. Peng, X. Chen, G. Yi, Z. Gao, Nanoparticulate Peroxidase/Catalase Mimetic and Its Application, Chem. - Eur. J. 18 (2012) 8906-8911.
[24] F. Xu, D. Huang, C. Han, W. Shen, X. Lin, Y. Wang, SPINOL-derived phosphoric acids: synthesis and application in enantioselective Friedel− Crafts reaction of indoles with imines, J. Org. Chem. 75 (2010) 8677-868.
[25] H. Deng, W. Shen, Z. Gao, An Interference-Free Glucose Biosensor Based on an Anionic Redox Polymer-Mediated Enzymatic Oxidation of Glucose, ChemPhysChem 14 (2013) 2343-2347.
[26] H. Zhang, M. Shi, W. Shen, Z. Li, B. Zhang, R. Liu, R. Zhang, Damage or protection? The role of smoked crust on sandstones from Yungang Grottoes, J. Archaeol. Sci. 40 (2013) 935-942.
[27] S. Tang, Y. Chang, W. Shen, H. K. Lee, Selective extraction by dissolvable (nitriloacetic acid-nickel)-layered double hydroxide coupled with reaction with potassium thiocyanate for sensitive detection of iron (III), Talanta 154 (2016) 416-422.
[28] L. Liu, W. Shen, B. Zhang, Y. Han, Determination of proteinaceous binders for polychrome relics of Xumi mountain grottoes by using enzyme-linked immunosorbent assay and immunofluorescence microscopy, Inter. J. Conserv. Sci. 7 (2016) 3-14.
[29] L. Liu, W. Shen, B. Zhang, Q. Ma, Microchemical study of pigments and binders in polychrome relics from Maiji Mountain Grottoes in northwestern China, Microsc. Microanal. 22 (2016) 845-856.
[30] S. Tang, J. Sun, Y. Li, D. Xia, T. Qi, K. Liu, H. Deng, W. Shen*, H.K. Lee, pH-dependent selective ion exchange based on (EDTA-nickel)-layered double hydroxide to catalyze the polymerization of aniline for detection of Cu2+ and Fe3+, Talanta 187 (2018)287-294.
[31] J. Sun, Y. Li, C. Chen, T. Qi, D. Xia, W. Mao, T. Yang, L. Chen, W. Shen*, S. Tang*, Magnetic Ni/Fe layered double hydroxides nanosheets as enhancer for DNA hairpin sensitive detection of miRNA. Talanta 187(2018)265-271.
[32] W. Shen, Y. Li, T. Qi, S. Wang, J. Sun, H. Deng, H. Lu, C. Chen, L. Chen, Sheng Tang, Fluorometric determination of zinc(II) by using DNAzyme-modified magnetic microbeads, Microchimica Acta 185(2018) 447.
[33] S. Tang, T. Qi, P. D. Ansah, J. C. N. Fouemina, W. Shen, C. Basheer, Kee Hian Lee*, Single drop Microextraction，TrAC Trends in Analytical Chemistry, 108(2018) 306-313.
[34] Shen Wei, Sun Jun, Shi Lei, Tang Sheng*, Lee Hian Kee*. Needle-based sampling coupled with colorimetric reaction catalyzed by layered double hydroxide peroxidase mimic for rapid detection of the change of D-glucosed level in banana. Analytica Chimica Acta 1001 (2018) 845-856.
[35] Tang Sheng*, Sun Jun, Xia Dasha, Zang Bin, Gao Yuhua, Chen Chuanxiang*, Shen Wei, Lee Hian Kee*, In-syringe extraction using compressible and self-recoverable, amphiphilic graphene aerogel as sorbent for determination of phenols. Talanta 195(2019) 165-172.
[36] Deng Huimin, Tang Gangling, Fan Ziyan, Liu Shanshan, Li Zhonghao, Wang Ying, Bian Zhaoyang, Shen Wei, Tang Sheng*, Yang Fei*, Use of autoclave extraction-supercritical fluid chromatography/tandem mass spectrometry to analyze 4-(methylintrosamino)-1-(3-pyridyl)-1-butanone and N'-nitrosonornicotine in tobacco, Journal of Chromatography A1595(2019) 207-214.
[37] Tang Sheng*, Li Yana, Zhu Anni, Yao Yao, Sun Jun, Zheng Fenfen, Lin Zixia, Shen Wei*, A triple-amplification strategy based on the formation of peroxidase-like two dimensional DNA/Fe3O4 networks initiated by hybridization chain reaction for highly sensitive detection of microRNA, Chemical Communications, 55 (2019) 8386-8389.
[38] Li Yana, Sun Jun, Mao Wei, Tang Sheng*, Liu Kai, Qi Tong, Deng Huimin, Shen Wei*, Chen Lizhuang, Peng Luming, Antimony doped tin oxide nanoparticles as peroxidase mimics for paper-based colorimetric detection of glucose using smartphone read-out, Microchimica Acta, 186 (2019) 403.
[39] Tang Sheng*, Qi Tong, Xia Dasha, Xu Mengchan, Xu Mengyuan, Zhu Anni, Shen Wei, Lee Hian Kee*, Smartphone nanocolorimetric determination of hydrogen sulfide in biosamples after silver-gold core-shell nanoprism-based headspace single drop microextraction, Analytical Chemistry, 91 (2019) 5888-5895.
[40] Tang Sheng*, Xia Dasha, Yao Yao, Chen Tianyu, Sun Jun, Yin Yijie, Shen Wei, Peng Yinxian, Dye adsorption by self-recoverable, adjustable amphiphilic graphene aerogel, Journal of Colloid and Interface Science, 554 (2019) 682-691.
[41] Tang Sheng*, Yao Yao, Chen Tianyu, Kong Dezhao, Shen Wei, Lee Hian Kee, Recent advances in the application of layered double hydroxides in analytical chemistry: A review, Analytica Chimica Acta, 1103 (2020) 32-48. Invited review.
[42] I. D. Tegladza, T. Qi, T. Chen, K. Alorku,S. Tang*, W. Shen*, D. Kong, A. Yuan, J. Liu, H. K. Lee*, Direct immersion single-drop microextraction of semi-volatile organic compounds in environmental samples: A review, J. Hazard. Mater. 393 (2020) 122403.
[43] Z. Li, C. Zhang, F. Han*, F. Wang, F. Zhang, W. Shen, C. Ye, X. Li, J. Liu*, Towards high-volumetric performance of Na/Li-ion batteries: a better anode material with molybdenum pentachloride–graphite intercalation compounds (MoCl5–GICs), J. Mater. Chem. A 8 (2020) 2430-2438.
[44] T. Qi, C. Song, J. He, W. Shen*, D. Kong, H. Shi, L.Tan, R. Pan, S. Tang*, H. K. Lee*, Highly Sensitive Detection of Multiple MicroRNAs by High-Performance Liquid Chromatography Coupled with Long and Short Probe-based Recycling Amplification, Anal. Chem. 2020, Accepted.DOI: 10.1021/acs.analchem.9b05301.
獲獎記錄
（1）國家優秀自費留學生獎學金，2015年
（2）新加坡國立大學總統獎學金，2014年
（3）新加坡國立大學理學院研究生最佳科研獎，2013年
