汪敏先

汪敏先，男，中國科學院大學專職教師。

基本介紹

• 中文名：汪敏先
• 畢業院校：中國科學院大學
• 學位/學歷：博士
• 職業：教師

人物經歷

教育背景

2009-09--2015-01 中國科學院大學 博士

2005-09--2009-06 吉林大學 學士

工作經歷

2018-01~2021-08,The Broad Institute of MIT and Harvard, Computational Biologist

2015-03~2018-01,Harvard Medical School, Postdoc

2009-09~2015-01,中國科學院大學, 博士

2005-09~2009-06,吉林大學, 學士

出版信息

發表論文

（1） Genetic Predictor to Identify Individuals With High Lipoprotein(a) Concentrations, Circulation-Genomic and Precision Medicine, 2021, 第 2 作者

（2） Editorial: Computational Methods in Predicting Complex Disease Associated Genes and Environmental Factors, Frontiers in Genetics, 2021, 第 4 作者

（3） De novo TRIM8 variants impair its protein localization to nuclear bodies and cause developmental delay, epilepsy, and focal segmental glomerulosclerosis, American journal of human genetics, 2021, 第 8 作者

（4） Validation of a Genome-Wide Polygenic Score for Coronary Artery Disease in South Asians, Journal of the American College of Cardiology, 2020, 第 1 作者

（5） Polygenic background modifies penetrance of monogenic variants for tier 1 genomic conditions, Nature Communications, 2020, 第 2 作者

（6） Autosomal Dominant Tubulointerstitial Kidney Disease—Uromodulin Misclassified as Focal Segmental Glomerulosclerosis or Hereditary Glomerular Disease, Kidney International Reports, 2020, 第 2 作者

（7） Association of Rare Pathogenic DNA Variants for Familial Hypercholesterolemia, Hereditary Breast and Ovarian Cancer Syndrome, and Lynch Syndrome With Disease Risk in Adults According to Family History, JAMA Network Open, 2020, 第 2 作者

（8） Lp(a) (Lipoprotein [a]) Concentrations and Incident Atherosclerotic Cardiovascular Disease, Arteri osclerosis, Thrombosis, and Vascular Biology, 2020, 第 2 作者

（9） Genome-Wide Polygenic Score and Cardiovascular Outcomes With Evacetrapib in Patients With High-Risk Vascular Disease, Circulation-Genomic and Precision Medicine, 2020, 第 3 作者

（10） Phosphorylation of ACTN4 leads to podocyte vulnerability and proteinuric glomerulosclerosis, Journal of the American Society of Nephrology, 2020, 第 8 作者

（11） Analysis of cardiac magnetic resonance imaging in 36,000 individuals yields genetic insights into dilated cardiomyopathy, Nature Communications, 2020, 第 3 作者

（12） Contributions of Rare Gene Variants to Familial and Sporadic FSGS, American Society of Nephrology, 2019, 第 1 作者

（13） Volanesorsen, familial chylomicronemia syndrome, and thrombocytopenia, New England Journal of Medicine, 2019, 第 2 作者

（14） APOL1-Associated Kidney Disease in Brazil, Kidney International Reports, 2019, 第 3 作者

（15） Rare Genetic Variants Associated With Sudden Cardiac Death in Adults, Journal of the American College of Cardiology, 2019, 第 4 作者

（16） UBD modifies APOL1-induced kidney disease risk, Proceedings of the National Academy of Sciences of the United States of America, 2018, 第 2 作者

（17） Disease-causing mutation in alpha-actinin-4 promotes podocyte detachment through maladaptation to periodic stretch, Proceedings of the National Academy of Sciences of the United States of America, 2018, 第 5 作者

（18） A probabilistic method for testing and estimating selection differences between populations, Genome Research, 2015, 第 2 作者

（19） Composition and Interactions of Hepatitis B Virus Quasispecies Defined the Virological Response During Telbivudine Therapy, Scientific Reports, 2015, 第 8 作者

（20） Detecting Recent Positive Selection with High Accuracy and Reliability by Conditional Coalescent Tree, Molecular Biology and Evolution, 2014, 第 1 作者

（21） A Monte Carlo Permutation Test for Random Mating Using Genome Sequences, PLos One, 2013, 第 2 作者

（22） Resolving ambiguity in the phylogenetic relationship of genotypes A, B, and C of hepatitis B virus, BMC Evolutionary Biology, 2013, 第 2 作者