基本介紹
- 中文名：池哲
- 學位/學歷：博士
- 職業：教師
- 專業方向：微生物學、生物化學與分子生物學、生物材料
- 任職院校：中國海洋大學
研究方向,學術成果,榮譽獎項,
研究方向
微生物學、生物化學與分子生物學、生物材料。
微生物天然產物的合成及其生物醫學轉化；海洋生物大分子的醫學轉化。包括微生物天然產物的途徑解析；基於物種特異性基因作業系統的天然化合物的重構合成以及de novo合成；基於微生物天然化合物的新型靶向分子的合成；基於微生物天然化合物的生物感測器/促動器的構建以及其在病原微生物檢測中的套用；基於微生物天然大分子聚合物和海洋大分子聚合物的靶向給藥載體的構建及其在抗菌物質靶向遞送中的作用；微生物天然大分子聚合物-纖維素納米晶複合材料及其醫學轉化；基因工程微生物基材料。
學術成果
主持國家自然科學基金1項，主持山東省重點研發計畫2項，參與國家自然科學基金2項，累積到賬經費近100萬。
近年發表的SCI收錄文章：
1. Lu, Y.; Wang, H.; Wang, Z.; Cong, Y.; Zhang, P.; Liu, G.; Liu, C.; Chi, Z.; Chi, Z. *, Metabolic rewiring improves the production of the fungal active targeting molecule fusarinine C. ACS Synth Biol 2019, 8, 1755-1765.（IF: 5.571, Cover article）
2. Lu, Y.; Liu, G. L.; Jiang, H.; Chi, Z. M.; Chi, Z.*, An insight into the iron acquisition and homeostasis in Aureobasidium melanogenum HN6.2 strain through genome mining and transcriptome analysis. Funct. & Integr. Genomic. 2019,19 (1), 137-150. (IF: 2.745)
3. Zhang, Z.; Lu, Y.; Chi, Z.*; Liu, G. L.; Jiang, H.; Hu, Z.; Chi, Z. M., Genome editing of different strains of Aureobasidium melanogenum using an efficient Cre/loxp site-specific recombination system. Fungal Biol.2019, DOI: 10.1016/j.funbio.2019.06.001. (IF: 2.699)
4. Xue, S. J.; Chen, L.; Jiang, H.; Liu, G. L.; Chi, Z. M.; Hu, Z.; Chi, Z.*, High pullulan biosynthesis from high concentration of glucose by a hyperosmotic resistant, yeast-like fungal strain isolated from a natural comb-honey. Food Chem. 2019,286, 123-128. (IF: 5.399)
5. Jiang, H.; Xue, S. J.; Li, Y. F.; Liu, G. L.; Chi, Z. M.; Hu, Z.; Chi, Z.*, Efficient transformation of sucrose into high pullulan concentrations by Aureobasidium melanogenum TN1-2 isolated from a natural honey. Food Chem. 2018,257, 29-35. (IF: 5.399)
6. Chi, Z.; Liu, N. N.; Jiang, H.; Wang, Q. Q.; Chen, J. T.; Liu, G. L.; Hu, Z.; Chi, Z. M., Relationship between beta-D-fructofuranosidase activity, fructooligosaccharides and pullulan biosynthesis in Aureobasidium melanogenum P16. Int. J. Biol. Macromol. 2019,125, 1103-1111. (IF: 4.784)
7. Liu, N. N.; Chi, Z.*; Liu, G. L.; Chen, T. J.; Jiang, H.; Hu, Z.; Chi, Z. M., alpha-Amylase, glucoamylase and isopullulanase determine molecular weight of pullulan produced by Aureobasidium melanogenum P16. Int. J. Biol. Macromol. 2018,117, 727-734. (IF: 4.784)
8. Cong, Y.; Geng, J. Y.; Wang, H. Y.; Su, J.; Arif, M.; Dong, Q. J.; Chi, Z.*; Liu, C. G.*, Ureido-modified carboxymethyl chitosan-graft-stearic acid polymeric nano-micelles as a targeted delivering carrier of clarithromycin for Helicobacter pylori: Preparation and in vitro evaluation. Int. J. Biol. Macromol. 2019,129, 686-692. (IF: 4.784)
9. Luan, L.; Chi, Z.*; Liu, C. G.*, Chinese White Wax Solid Lipid Nanoparticles as a Novel Nanocarrier of Curcumin for Inhibiting the Formation of Staphylococcus aureus Biofilms. Nanomaterials 2019,9 (5). (IF: 4.034)
10. Kazharska, M.; Ding, Y. Y.; Arif, M.; Jiang, F.; Cong, Y.; Wang, H. Y.; Zhao, C. H.; Liu, X. M.; Chi, Z.*; Liu, C. G.*, Cellulose nanocrystals derived from Enteromorpha prolifera and their use in developing bionanocomposite films with water-soluble polysaccharides extracted from E. prolifera. Int. J. Biol. Macromol. 2019,134, 390-396. (IF: 4.784)
榮譽獎項
指導學生獲獎情況：中國海洋大學校長獎學金2項
