歐陽宏偉，男，浙江大學求是特聘教授，愛丁堡大學榮譽教授博士生導師， 現任現任浙江大學醫學院副院長，浙江大學愛丁堡大學聯合學院（中方）院長；傑出青年基金項目獲得者；全國骨科醫師協會“首屆骨科十最佳醫生”；愛思唯爾2015/2016/2017/2018年中國高被引學者。美國醫學與生物工程院(AIMBE) 會士（fellow），國際聯合骨科研究學會（ICORS）會士（fellow），“十三五”國家重點研發計畫“生物醫用材料研發與組織器官修復替代”重點專項專家組副組長，中國生物醫學工程學會組織工程與再生醫學分會主任委員，中國研究型醫院學會運動醫學專業委員會副主任委員，中國生物材料學會再生醫學材料分會副主任委員。
歐陽宏偉教授一直專注於肌腱、軟骨組織工程和再生治療。在肌腱、軟骨基礎研究和組織工程套用基礎研究方面做了成系列的工作，形成了自己的研究體系和學術觀點。
基本介紹
- 中文名稱：歐陽宏偉
- 國籍：中國
- 民族：漢族
- 出生日期：1971年11月
- 畢業院校：新加坡國立大學
- 學歷：組織工程學博士
- 職務：浙江大學醫學院副院長
研究方向,教育經歷,工作經歷,學術兼職,獲獎情況,主要論文,
研究方向
1.骨關節軟骨組織工程及臨床再生治療
2.肌腱韌帶的組織工程研究
3.幹細胞生物學和套用技術
4.細胞治療技術
教育經歷
1989-1994湖南醫科大學(現中南大學湘雅醫學院)臨床醫學本科
1999-2002新加坡國立大學醫學院組織工程學博士學位
2002-2004新加坡國立大學工程學院生物工程學博士後研究
2004-2005新加坡國立大學醫院/大學組織工程中心Clinical Scientist
工作經歷
◆ 2004-2005新加坡國立大學醫院，臨床組織工程中心，Clinical Scientist
◆2003-2004新加坡國立大學工程學院，生物工程學，博士後
◆1999-2003新加坡國立大學醫學院骨科，骨科學，博士
◆1994-1999中南大學湘雅醫院，骨科，醫師
◆1989-1994湖南醫科大學(現中南大學湘雅醫學院)，臨床醫學，學士
學術兼職
“十三五”國家重點研發計畫“生物醫用材料研發與組織器官修復替代”重點專項專家組副組長
中國生物醫學工程學會組織工程與再生醫學分會主任委員
中國研究型醫院學會運動醫學專業委員會副主任委員
中國生物材料學會再生醫學材料分會副主任委員
浙江省組織工程與再生醫學技術重點實驗室主任
十多個國際學術（SCI）期刊的審稿人（reviewer position）。
獲獎情況
代表性獎項
◆骨軟骨原位修復與再生技術，教育部2019年度高等學校科學研究優秀成果獎（技術發明）一等獎，本人排名：1/6
◆運動系統組織工程與修復再生技術，中國生物材料學會科學技術獎二等獎，2019年，本人排名：1/6
◆肌腱分化和再生的研究,教育部2014年度高等學校科學研究優秀成果獎（科學技術）自然科學獎二等獎,本人排名：1/7
◆運動系統組織工程技術,教育部2012年度高等學校科學研究優秀成果獎（科學技術）科技進步獎一等獎,本人排名：1/6
◆ 中國醫師協會骨科醫師分會2014年度“全國十佳中青年骨科醫師
榮譽
◆International Combined Orthopaedics Research Society（ICORS）/國際骨科聯合研究學會，會士
◆American institute of medical and biological engineer(AIMBE) /美國醫學與生物工程院，會士（受聘儀式將於2020年3月舉行）
◆2015-2018連續四年入選愛思唯爾中國高被引學者（生物醫學工程）
主要論文
代表性論文
- Yi Hong #, Fei Fei Zhou #, Yu Jie Hua, Xian Zhu Zhang, Cheng Yao Ni, Di Hao Pan, Yi Qing Zhang, De Ming Jiang, Long Yang, Qiu Ning Lin, Yi Wei Zou, Dong Sheng Yu, David E. Arnot, Xiao Hui Zou, Lin Yong Zhu, Shu Fang Zhang, Hong Wei Ouyang*. A strongly adhesive haemostatic hydrogel for the repair of arterial and heart bleeds.Nature Communications. 2019.被國家科技部、英國每日郵報、NewScientist、BioArt、DeepTech等報導
- Qiulin He#, Jingwei Zhang#, Youguo Liao, Enateri Verissarah Alakpa, Varitsara Bunpetch, Jiayan Zhang, Hongwei Ouyang⁎. Current advances in microsphere based cell culture and tissue engineering.Biotechnology Advances.2019
- Shou An Zhu#, Jian Xi Zhu#, Ge Hua Zhen, Yi He Hu, Sen Bo An, Yu Sheng Li, Qin Zheng, Zhi Yong Chen, Ya Yang, Mei Wan, Richard Leroy Skolasky, Yong Cao, Tian Ding Wu, Bo Gao, Mi Yang, Man Man Gao, Julia Kuliwaba, Shuang Fei Ni, Lei Wang, Chuan Long Wu, David Findlay, Holger K. Eltzschig, Hong Wei Ouyang, Janet Crane, Feng Quan Zhou, Yun Guan, Xin Zhong Dong, Xu Cao*.Subchondral bone osteoclasts induce sensory innervation and osteoarthritis pain.The Journal of Clinical Investigation.2019.
- Wen Yan Zhou, Jun Xin Lin, Kun Zhao, Kai Xiu Jin, Qiu Lin He, Ye Jun Hu, Gang Feng, You Zhi Cai, Chen Xia, Hua Liu, Wei Liang Shen, Xue Qing Hu, Hong Wei Ouyang*. Single-cell profiles and clinically useful properties of human mesenchymal stem cells of adipose and bone marrow origin.The American Journal of Sports Medicine.2019.
- Hao Ren, Xu Ri Chen, Meng Ya Tian, Jing Zhou, Hong Wei Ouyang*, Zhi Yong Zhang*. Regulation of inflammatory cytokines for spinal cord injury repair through local delivery of therapeutic agents.Advanced Science.2018.
- Jun Dai#, Dong Sheng Yu#, Ya Fei Wang, Yi Shan Chen, Heng Sun, Xiao Lei Zhang, Shou An Zhu, Zong You Pan, Boon Chin Heng, Shu Fang Zhang, Hong Wei Ouyang*.Kdm6b regulates cartilage development and homeostasis through anabolic metabolism.Annals of the Rheumatic Diseases. 2017.被Faculty 1000推薦
- Zi Yin#, Jia Jie Hu#, Long Yang, Ze Feng Zheng, Cheng Rui An, Bing Bing Wu, Can Zhang, Wei Liang Shen, Huan Huan Liu, Jia Lin Chen, Boon Chin Heng, Guo Ji Guo, Xiao Chen*, Hong Wei Ouyang*.Single-cell analysis reveals a nestin(+) tendon stem/progenitor cell population with strong tenogenic potentiality.Science Advances. 2016.
- Shou An Zhu, Ping Lu, Huan Huan Liu, Peng Fei Chen, Yan Wu, Yan Yan Wang, Heng Sun, Xiao Lei Zhang, Qing Qing Xia, Boon Chin Heng, Yi Ting Zhou, Hong Wei Ouyang*.Inhibition of Rac1 activity by controlled release of NSC23766 from chitosan microspheres effectively ameliorates osteoarthritis development in vivo.Annals of the Rheumatic Diseases.2015.被Nature Rheumatology Reviews highlight
- Yan Wu, Shou An Zhu, Cheng Tie Wu*, Ping Lu, Chang Chang Hu, Si Xiong, Jiang Chang, Boon Chin Heng, Yin Xiao, Hong Wei Ouyang*.A Bi-Lineage Conducive Scaffold for Osteochondral Defect Regeneration.Advanced Functional Materials. 2014.
- Bing Bing Wu#, Yu Li#, Nan Fang Nie, Jia Qi Xu, Cheng Rui An, Yi Xiao Liu, Ya Fei Wang, Yi Shan Chen, Lin Gong, Qi Kai Li, Elena Giusto, Varitsara Bunpetch, Dan Dan Zhang, Hong Wei Ouyang**, Xiao Hui Zou*. Nano genome altas (NGA) of body wide organ responses.Biomaterials.2019.
- Xu Dong Yao, Wei Wei, Xiao Zhao Wang, Cheng Lin Li, Mikael Björklund, Hong Wei Ouyang*. Stem cell derived exosomes: microRNA therapy for age-related musculoskeletal disorder.Biomaterials.2019
- Varitsara Bunpetch, Xiao An Zhang, Tian Li, Jun Xin Lin, Ewetse Paul Maswikiti, Yan Wu, Dan Dan Cai, Jun Li, Shu Fang Zhang, Cheng Tie Wu, Hong Wei Ouyang*. Silicate-based bioceramic scaffolds for dual-lineage regeneration of osteochondral defect.Biomaterials.2019.
- Varitsara Bunpethc, Zhi Yong Zhang*, Xiao An Zhang, Shan Han, Zong You Pan, Hao Yu Wu, Hong Wei Ouyang*. Strategies for MSC expansion and MSC-based microtissue for bone regeneration.Biomaterials.2019.
- Can Zhang, Er Chen Zhang, Long Yang, Wenjing Tu, Junxin Lin, Chunhui Yuan, Varisara Bumpetch, Xiao Chen**, Hongwei Ouyang*. Histone deacetylase inhibitor treated cell sheet from mouse tendon stem/progenitor cells promotes tendon repair.Biomaterials.2018.
- Zong You Pan#, Heng Sun#, Bin Bin Xie, Dong Dong Xia, Xiao An Zhang, Dong Sheng Yu, Jun Li, Yu Zi X, Zu Hua Wang, Yan Wu, Xiao Lei Zhang, Ya Fei Wang, Qian Bao Fu, Wei Hu, Yang Yang, Varitsara Bunpetch, Wei Liang Shen, Boon Chin Heng, Shu Fang Zhang*, Hong Wei Ouyang*. Therapeutic effects of gefitinib-encapsulated thermosensitive injectable hydrogel in intervertebral disc degeneration.Biomaterials.2018.
- Huan Huan Liu#, Hong Ju Pen#, Yan Wu, Can Zhang, You Zhi Cai, Guo Wei Xu, Qin Li, Xiao Chen, Jun Feng Ji, Yan Zhong Zhang*, Hong Wei Ouyang*. The promotion of bone regeneration by nanofibrous hydroxyapatite/chitosan scaffolds by effects on integrin-BMP/Smad signaling pathway in BMSCs.Biomaterials.2013.ESI Top 1%
- Zi Yin#, Xiao Chen#, Jia Lin Chen, Wei Liang Shen, Thi Minh Hieu Nguyen, Ling Gao, Hong Wei Ouyang*. The regulation of tendon stem cell differentiation by the alignment of nanofibers.Biomaterials.2010.ESI Top 1%
- Wen Yan Zhou, Jun Xin Lin, Kun Zhao, Kai Xiu Jin, Qiu Lin He, Ye Jun Hu, Gang Feng, You Zhi Cai, Chen Xia, Hua Liu, Wei Liang Shen, Xue Qing Hu, Hong Wei Ouyang*. Single-Cell Profiles and Clinically UsefulProperties of Human Mesenchymal StemCells of Adipose and Bone Marrow Origin.American Journal of Sports Medicine. 2019美國運動醫學骨科學會會刊
- Bing Bing Wu#, Cheng Rui An#, Yu Li, Zi Yin, Lin Gong, Zhen Li Li, Yi xiao Liu, Boon Chin Heng, Dan Dan Zhang, Hong Wei Ouyang*, Xiao Hui Zou*. Reconstructing lineage hierarchies of mouseuterus epithelia development using single-cell analysis.Stem Cell Reports.2017
- Jia Jie Hu, Zi Yin, Wei Liang Shen, Yu Bin Xie, Ting Zhu, Ping Lu, You Zhi Cai, Min Jian Kong, Boon Chin Heng, Yi Ting Zhou, Wei Shan Chen, Xiao Chen, Hong Wei Ouyang*. Pharmacological regulation of in situ tissue stem cells differentiation for soft tissue calcification treatment.Stem Cells.2016
- Yang Zi Jiang, You Zhi CAI, Wei Zhang, Zi Yin, Chang Chang HU, Tong Tong, Ping Lu, Shu Fang Zhang, Dante Neculai, Rocky S. Tuan*, Hong Wei Ouyang*. Human cartilage-derived progenitor cells from committed chondrocytes for efficient cartilage repair and regeneration.Stem Cells Translational Medicine.2016.被Stem Cells同期專門評述，並被國家自然科學基金委編輯成簡報報送中共中央各部委
- Huan Huan Liu, Can Zhang, Shou An Zhou, Ping Lu, Ting Zhu, Xiao Nan Gong, Zi Wang Zhang, Jia Jie Hu, Zi Yin, Boon Chin Heng, Xiao Chen*, Hong Wei Ouyang*.Mohawk promotes the tenogenesis of mesenchymal stem cells through activation of the TGFβ signaling pathway.Stem Cells.2015.
- Xiao Chen, Xing Hui Song, Zi Yin, Xiao Hui Zou, Lin Lin Wang, Hu Hu, Tong Cao, Ming Hao Zheng, Hong Wei Ouyang*. Stepwise differentiation of human embryonic stem cells promotes tendon regeneration by secreting fetal tendon matrix and differentiation factors.Stem Cells.2009.
- Hong Wei Ouyang, James C.H. Goh*, Ashvin Thambyah, Swee Hin Teoh, Eng Hin Lee. Knitted poly-lactide-co-glycolide scaffold loaded with bone marrow stromal cells in repair and regeneration of rabbit achilles tendon.Tissue Engineering. 2003.高被引文章
