楊文強，男，博士，研究員，博士生導師。中國科學院植物研究所研究員。
基本介紹
- 中文名：楊文強
- 國籍：中國
- 畢業院校：東北農業大學、中國科學院遺傳與發育生物學研究所
- 職稱：中國科學院植物研究所研究員
人物經歷,研究方向,研究論文,
人物經歷
2000年和2003年在東北農業大學分別獲學士和碩士學位。
2008年在中國科學院遺傳與發育生物學研究所獲博士學位。
2009年2月至2017年1月在美國斯坦福卡內基研究所植物生物學系從事博士後研究和研究助理工作。期間於2009年3月至5月在美國科羅拉多再生能源國家實驗室（NREL）訪問研究。2017年2月到中國科學院植物研究所工作。
研究方向
光合作用是世界上最重要的化學反應（1988年諾貝爾獎頒獎詞），與人類生存息息相關。實驗室致力於光合作用代謝調控機制研究。以衣藻和大豆等豆科植物為研究對象，運用遺傳學、生理學、細胞學、分子生物學、生物化學、生物物理學和組學等多學科的理論與技術，挖掘關鍵因子、揭示分子機理，更好的理解光合作用調控機制，為農業科技發展提供理論指導和技術支持。研究方向包括：
（1）光合作用新的調控機制。
衣藻基因組測序發現597個在光合生物中有同源，而非光合生物中不存在的蛋白，這些蛋白被命名為GreenCut，且絕大部分蛋白的功能是未知的。試圖剖析這些蛋白可能在光合作用過程中發揮新的不為所知的功能。
（2）光合作用與碳代謝互作網路。
光合作用形成的磷酸丙糖的去向直接決定了有機碳的分配，系統的研究這些參與碳代謝網路中酶類，如澱粉酶、磷酸果糖激酶與光合作用的相互作用機制，試圖探討光合作用和這些重要碳代謝網路的互作關係。
（3）葉綠體蛋白轉運與蛋白質量控制。
葉綠體是光合作用發生的場所，同時也是重要的生物反應器合成脂質、胺基酸等物質；傳遞逆向信號、調節細胞內能量和氧化還原平衡；葉綠體還參與了植物的激素合成、抗病、免疫以及環境適應等。葉綠體諸多功能的行使離不開蛋白質的參與。研究物種在長期進化過程中，葉綠體蛋白轉運和蛋白質量控制的交流協作如何維持葉綠體的功能、調控葉綠體的發育以及理解葉綠體與其它細胞器蛋白質量控制網路的互作等、具有非常重要的意義。
（4）大豆等豆科植物光合作用高光效機理。
大豆是一種重要的糧食作物，幾乎存在於人類飲食的方方面面，對人類生活具有重要的意義。但目前大豆光合作用光能高效利用存在瓶頸、亟待建立高效光合作用新體系，通過篩選大豆高光效材料，鑑定大豆高光效的遺傳調控因子，解析高光效的分子調控機理，獲得可用於作物高光效的分子調控網路，為實現大豆的高產提供理論支持。
研究論文
2022
Shuaiqi Zhu, Song Bin,Wenda Wang, Shan Lu*, Wenqiang Yang*, 2022. Exogenous arachidonic acid affects fucoxanthin biosynthesisand photoprotectionin Phaeodactylum tricornutum. Mar Drugs. 20(10): 644
Jiale Xing, Junting Pan,Heng Yi, Kang Lv, Qiuliang Gan, Meimei Wang, Haitao Ge, Xiahe Huang, Fang Huang,Yingchun Wang, Jean-David Rochaix, Wenqiang Yang*, 2022. The plastid-encoded protein Orf2971 is required for proteintranslocation and chloroplast quality control. The Plant Cell. 34(9):3383-3399.
Ying Lv, Fei Han, MengxiaLiu, Ting Zhang, Guanshen Cui, Jiaojiao Wang, Ying Yang, Yungui Yang, WenqiangYang*, 2022. Characteristics ofN-methyladenosine modification during sexualreproduction of Chalmydomonasreinhardtii. GenomProteom Bioinf. doi:10.1016/j.gpb.2022.04.004.
Li J, Yuan J, Li Y, SunH, Ma T, Huai J, Yang W, Zhang W, Lin R*, 2022. The CDC48 complex mediates ubiquitin-dependent degradation ofintra-chloroplast proteins in plants. Cell Rep. 39(2): 110664.
Chao Han, Wenbo Hua, JingeLi, Yan Qiao, Yao Lianmei, Wei Hao, Ruizhi Li, Min Fan, Geert De Jaeger, WenqiangYang and Ming-Yi Bai*, 2022. TORpromotes guard cell starch degradation by regulating the activity of β-AMYLASE1in Arabidopsis. The Plant Cell. 34(3): 1038-1053.
2021
Wenfeng Tu, Lishuan Wu, Chunyan Zhang, Ruixue Sun, Liangsheng Wang, Wenqiang Yang, Chunhong Yang and Cheng Liu. 2021, Neoxanthin affects the stability of the C2S2M2-type photosystem II supercomplexes and the kinetics of state transition in Arabidopsis. Plant J, 104(6): 1724-1735.
2020
楊文強*，郭夢曦.2020.藻類與光合作用.生命世界. 2: 30-31
2019
Zhiyun Li, Weiping Mo; Liqiang Jia, Yong-Chao Xu, Weijiang Tang, Wenqiang Yang, Ya-Long Guo, Rongcheng Lin, 2019. Rice FLUORESCENT1 Is Involved in the regulation of chlorophyll. Plant Cell Physiol, 60(10): 2307-2318.
Jin Liu, Zheng Sun, Xuemei Mao, Gerken Henri, Xiaofei Wang, Wenqiang Yang. 2019. Multiomics analysis reveals a distinct mechanism of oleaginousness in the emerging model alga Chromochloris zofingiensis. Plant J, doi: 10.1111/tpj.14302.
Yue Wang, Huanling Yang, Xinna Zhang, Fei Han, Wenfeng Tu and Wenqiang Yang. 2019. Microalgal hydrogen production. Small Methods, 4: 1900514.
2018
Wittkopp TM, Saroussi S, Yang W, Johnson X, Kim RG, Heinnickel ML, Russell JJ, Phuthong W, Dent RM, Broeckling CD, Peers G, Lohr M, Wollman FA, Niyogi KK, Grossman AR*. 2018. GreenCut protein CPLD49 of Chlamydomonas reinhardtii associates with thylakoid membranes and is required for cytochrome b6f complex accumulation. Plant J., 94: 1023-1037.
塗文鳳, 王月, 楊文強*. 2018. 基因編輯技術在萊茵衣藻中的套用進展. 生命科學, 30: 987-993.
2016
Mark Heinnickel, Rick Kim, Tyler M Wittkopp, Wenqiang Yang, Karim Walters, Stephen Herbert, Arthur R Grossman. 2016. Tetratricopeptide repeat protein protects photosystem I from oxidative disruption during assembly. PNAS. 113(10): 2774-2779
2015
Wenqiang Yang*, Tyler M Wittkopp, Xiaobo Li, Jaruswan Warakanont, Alexandra Dubini, Rick Kim, Claudia Catalanotti, Eva C M Nowack, Munevver Aksoy, Sarah D’Adamo, Luke Mackinder, Dudley Page, Mark Heinnickel, Xenie Johnson, Jean Alric, Martin C Jonikas, Christoph Benning, Sabeeha Merchant, Matthew C Posewitz, Arthur R Grossman. 2015. Critical role of Chlamydomonas reinhardtii ferredoxin-5 in maintaining membrane structure and dark metabolism. PNAS. 112(48): 14978-14983 (#Equal Contribution)
Wenqiang Yang*, Claudia Catalanotti, Sarah D’Adamo, Tyler M Wittkopp, Cheryl J Ingram-Smith, Luke Mackinder, Tarryn Miller, Adam L. Heuberger, Graham Peers, Kerry S Smith, Martin C Jonikas, Arthur R Grossman, Matthew C Posewitz. 2015. Alternative Acetate Production Pathways in Chlamydomonas reinhardtii during Dark Anoxia and the Dominant Role of Chloroplasts in Fermentative Acetate Production. The Plant Cell. 26(11):4499-4518
2013
Deqiang Duanmu, Nathan C Rockwell, Rachel M Dent, Krishna Niyogi, Wenqiang Yang, Arthur R Grossman, Clark Lagarias. 2013. Retrograde bilin signaling enables Chlamydomonas greening and phototrophic survival. PNAS.110(9):3621-3626
Mark Heinnickel ML, Jean Alric, Tyler M Wittkopp, Wenqiang Yang, Claudia Catalanotti, Rachel Dent, Krishina Niyogi, Francis-Andrew Wollman, Arthur R Grossman. 2013. Novel Thylakoid Membrane GreenCut Protein CPLD38 Impacts Accumulation of the Cytochrome b6f Complex and Associated Regulatory Processes. J Biol Chem. 288(10):7024-7036
2012
Claudia Catalanotti, Alexandra Dubini, Venkataramanan Subramanian, Wenqiang Yang, Leonardo Magneschi, Florence Mus, Michael Seibert, Matthew C Posewitz, Arthur R Grossman. 2012. Altered Fermentative Metabolism in Chlamydomonas reinhardtii Mutants Lacking Pyruvate Formate Lyase and both Pyruvate Formate Lyase and Alcohol Dehydrogenase. The Plant Cell. 24:692-707
Leonardo Magneschi, Claudia Catalanotti, Alexandra Dubini, Wenqiang Yang, Matthew C Posewitz, Michael Seibert, Pierdomenico Perata, Arthur R Grossman. 2012. A Mutant in the ADH1 Gene of Chlamydomonas reinhardtii Elicits Metabolic Restructuring during Anaerobiosis. Plant Physiology.158(3):1293-1305
2011
Jonathan E. Meuser, Sarah D’Adamo, Robert E Jinkerson, Florence Mus, Wenqiang Yang, Maria L Ghirardi, Michael Seibert, Arthur R Grossman, Matthew CPosewitz. 2011. Genetic Disruption of both Chlamydomonas reinhardtii [FeFe]-Hydrogenases: Insight into the Role of HYDA2 in H2 Production. Biochem Biophys Res Commun. 417(2):704-709
David Gonzalez-Ballester, Wirulda Pootakham, Florence Mus, Wenqiang Yang, Claudia Catalanotti, Leonardo Magneschi, Jose J. Higuera, Amaury de Montaigu, Matthew Prior, Aurora Galván, Emilio Fernandez, Arthur R Grossman. 2011. Reverse Genetics in Chlamydomonas: A Moderate Throughput Platform for Isolating Insertional Mutants. Plant Methods.7:24. doi:10.1186/1746-4811-7-24
Wenying Xu, Rendong Yang, Meina Li, Zhuo Xing, Wenqiang Yang, Guang Chen, Han Guo, Xiaojie Gong, Zhou Du, Zhenhai Zhang, Xingming Hu, Dong Wang, Qian Qian, Tai Wang, Zhen Su, Yongbiao Xue. 2011. Transcriptome Phase Distribution Analysis Reveals Diurnal Regulated Biological Processes and Key Pathways in Rice Flag Leaves and Seedling Leaves. PLoS One. 6(3): e17613
2010及以前
Wenqiang Yang, Ying Lai, Meina Li,Wenying Xu,YongbiaoXue. 2008. A Novel C2-domain-Containing Phospholipid Binding Protein, OsPBP1, Is Involved in Pollen Fertility in Rice (Oryza sativa L.). Molecular Plant. 1: 770-785
Wenqiang Yang, Zhaosheng Kong,Edith Omo-Ikerodah, Wenying Xu,Yongbiao Xue. 2008. A Calcineurin B-Like Interacting Protein Kinase OsCIPK23 Functions in Pollination and Drought Stress Responses in Rice. Journal of Genetics and Genomics. 35:531-543
Meina Li, Wenying Xu, Wenqiang Yang, Zhaosheng Kong,Yongbiao Xue. 2007. Genome-Wide Gene Expression Profiling Reveals Conserved and Novel Molecular Functions of the Stigma in Rice (Oryza sativa L.). Plant Physiology.144:1797-1812
Zhaosheng Kong, Meina Li, Wenqiang Yang, Wenying Xu,Yongbiao Xue. 2006. A Novel Nuclear-Localized CCCH-type Zinc Finger Protein, OsDOS, Is Involved in Delaying Leaf Senescence in Rice (Oryza sativa L.). Plant Physiology. 141: 1376–1388
Reviews and Book Chapters
Tyler M Wittkopp, Shai Saroussi, Wenqiang Yang, Arthur R Grossman. 2015. Chapter 11: The GreenCut - a tool for understanding the functions and relationships of proteins conserved in green lineage organisms. Horizon: Chloroplasts: Current Research and Applications
Wenqiang Yang*, Claudia Catalanotti, Tyler M Wittkopp Matthew C Posewitz, Arthur R Grossman. (2014). Algae after dark: mechanisms to cope with anoxic/hypoxic conditions. Coming of age of Chlamydomonas as a model alga. Plant Journal 82(3):481-503
Wenqiang Yang*, Claudia Catalanotti, Matthew C Posewitz, Jean Alric, Arthur R Grossman. 2014. Insight into Algal Fermentation Metabolism. Springer: Low Oxygen Stress in Plants.
Claudia Catalanotti, Wenqiang Yang, Matthew C Posewitz, Arthur R Grossman. 2013. Fermentation metabolism and its evolution in algae. Frontiers in Plant Science. doi: 10.3389/fpls.2013.00150
Arthur R Grossman, Claudia Catalanotti, Wenqiang Yang, Alexandra Dubini, Leonardo Magneschi, Venkataramanan Subramanian, Matthew C Posewitz, Michael Seibert. 2011. Multiple Facets of Anoxic Metabolism and Hydrogen Production in the Unicellular Green Alga Chlamydomonas reinhardtii. New Phytologist. 190(2): 279-88
