梅茜(中國科學院研究員)

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梅茜,女,中國科學院蘇州生物醫學工程技術研究所研究員,主要從事微流控技術發展和相關儀器開發及其在生化檢測和臨床轉化醫學中的套用研究,對塑膠材料製備微流控晶片進行了大量研究,在微流控晶片設計、材料選擇、製造工藝、批量生產和質控等方面都積累了豐富的經驗,在體外蛋白質合成微流控晶片、單分子基因掃描測序的微流控系統、DNA 納米結構的分離微流控晶片、多重核酸和蛋白質定量檢測等研究方向也取得了一些創新型成果。

基本介紹

研究方向,代表論著,

研究方向

一體化微流控晶片;微流控系統在快速分析、臨床診斷、基因組和蛋白質組的套用;功能化DNA納米自組裝。

代表論著

Publication
Q. Mei, R.H. Johnson, X. Wei, F. Su, Y.Liu, L. Kelbauskas, S. Lindsay, D.R. Meldrum, H. Yan. "On-chip isotachophoresis separation of functional DNA origami capture nanoarrays from cell lysate", Nano Research, 2013, 6, 712–719
H. Lu, F. Su, Q. Mei, Y. Tian, W. Tian, R.H.Johnson, D.R. Meldrum. "Using fluorinecontaining amphiphilic random copolymers to manipulate the quantum yields of aggregation induced emission fluorophores in aqueous solutions and the use of these polymers for fluorescent bioimaging", Journal of Materials Chemistry, 2012, 22(19), 9890-9900
H. Lu, F. Su, Q. Mei, X. Zhou, Y. Tian, W. Tian, R.H. Johnson, D.R. Meldrum. “A Series of poly[N-(2-hydroxypropyl)methacrylamide] copolymers with anthracene-derived fluorophores showing aggregation-Induced emission properties for bioimaging”, Journal of Polymer Science Part A, 2012, 50(5):890-899
F. Su, R. Alam, Q. Mei, Y. Tian, C. Youngbull, R.H. Johnson, D.R. Meldrum. "Nanostructured oxygen sensor using micelles to incorporate a hydrophobic platinum porphyrin", PLoS One, 2012, 7(3): e33390
Q. Mei, X. Wei, F. Su, Y. Liu, C. Youngbull, R.H. Johnson, S. Lindsay, H. Yan, D. R. Meldrum. “Stability of DNA origami nanoarrays in cell lysate”, Nano Letter, 2011, 11, 1477–1482
F. Su, R. Alam, Q. Mei, Y. Tian, D.R. Meldrum, "Micelles as delivery vehicles for oligofluorene for bioimaging", PLoS One, 2011, 6(9): e24425
Q. Mei, R. Khnouf, A. Simon, H.Z. Fan. “Protein synthesis in a device with nanoporous membranes and microchannels”, Lab on a chip, 2010, 10, 2541-2545
Q. Mei, Z. Xia, F. Xu, S. Soper, H.Z. Fan. “Fabrication of microfluidic reactors and mixing studies for luciferase detection.” Analytical Chemistry, 2008, 15, 6045–6050
Q. Mei, C.K. Fredrickson, A. Simon, R. Khnouf, H.Z. Fan. “Cell-free protein synthesis in microfluidic array device”, Biotechnology Progress, 2007, 23, 1305-1311
Q. Mei, C.K. Fredrickson, W. Lian, S. Jin, H.Z. Fan. “Ricin detection by a biological signal amplification in a well-in-well device”, Analytical Chemistry, 2006, 78, 7659-7664
Q. Mei, C.K. Fredrickson, S. Jin, H.Z. Fan. “Toxin detection by a miniaturized in vitro protein expression array”, Analytical Chemistry, 2005, 77, 5494-5500
Patent
Fluorescent Nucleic Acid Probe Detection Cartridge Assembly Unit. USD787700 S1
微生物燃料電池陽極的免疫修飾處理方法. 專利號 201110227982.4
一種腫瘤細胞的培養檢驗裝置, 專利號 ZL01110250735.6

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