1980年首先將日本胃腸雙重對比造影技術引進國內,促進了我國X線胃腸道診斷水平的提高。1986-1995年先後承擔了國家“七五”、“八五”公關課題,“胃癌早期診斷與普查方法的研究”,自行設計了適合我國國情的“序貫篩查法”,使早期胃癌檢出率達到47.1%;“胃癌早期診斷新方法的研究”,研究出血清及胃癌自發螢光光譜診斷胃癌獲得成功。於1996年在山東胃癌高發區率先開展了幽門螺桿菌與胃癌關係的大宗人群干預試驗,經十年隨訪研究,得到了我國幽門螺桿菌與胃癌關係的寶貴資料,其研究成果受到國際認可,並被國內外同行廣泛引用,並在2007年 GUT 發表歐洲幽門螺桿菌處理的共識報告中作為A級證據。
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