李自超(中國農業大學農學院植物遺傳育種與種子科學系教授超)

李自超，男，博士，中國農業大學農學院植物遺傳育種與種子科學系教授。

基本介紹

• 中文名：李自超
• 畢業院校：中國農業大學
• 學位/學歷：博士
• 任職院校：中國農業大學

人物經歷

學習經歷

2010.1–2010.6 美國北卡州立大學訪問科學家

2002.2–2003.5 於國際水稻研究所（IRRI）合作研究

2001.6 於中國農業大學獲博士學位

1995.3-1996.3 保加利亞遺傳工程研究所訪問學者

1990.7 於北京農業大學獲碩士學位

1980.9-1984.7 在北京農業大學學習，並獲學士學位

工作經歷

2001.9 至今 中國農業大學植物遺傳育種系教授，博士生導師

1996.12-2001.9 中國農業大學植物遺傳育種系副教授

1990.12-1996. 6 中國農業大學植物遺傳育種系講師

1984.8-1990.12 北京農業大學植物遺傳育種系助教

社會兼職

擔任農業部作物基因組學與遺傳改良重點實驗室和北京市作物遺傳改良實驗室主任，中國農業大學植物遺傳育種系副系主任，中國作物品種資源學會理事，中國野生稻協作委員會委員，中國農業大學學報編委等職。

教學領域

曾先後主講普通遺傳學，植物細胞遺傳學，五大作物育種實踐教學，植物遺傳實驗技術，分子遺傳與遺傳工程基礎，作物遺傳育種Seminar等7門本科生和研究生課程。現主持碩士和博士研究生作物遺傳育種研究進展，並參與博士研究生的作物科學研究進展的專題講座。

研究方向

長期從事稻種資源和基因組學、稻作抗旱遺傳機理及其分子育種工作。在水稻遺傳資源核心種質研究方面率先提出核心種質構建系統的理論及技術體系，首次提出中國普通野生稻和栽培稻的遺傳結構，提出中國稻種資源遺傳多樣性分布規律,並對栽野演化及其栽培稻的分類提出新的見解。

主要利用旱稻DH、RIL和導入系群體及其種質資源通過連鎖分析和GWAS相結合發掘根系、生理等抗旱相關性狀的QTL或基因，利用基因組分析和RNA-Seq轉錄組分析技術研究了旱稻基因表達規律、旱稻抗旱的分子機制和旱生適應性進化；利用稻種核心種質培育的MCC-NAM群體和定向培育的產量性狀、耐冷性狀的近等基因系，通過連鎖分析和GWAS相結合高效發掘和克隆水稻重要功能基因。

獲獎記錄

1.雲南稻種資源核心種質庫的構建，2003年雲南省自然科學一等獎（第1完成人）

2.粳型水稻雜種優勢群的研究及其利用，2005年寧夏科技進步三等獎，第4完成人

3.國家重點基礎發展規劃研究（973計畫）先進個人，2004年，科技部

4.北京市教育創新標兵，2002年北京市總工會（個人獎）

5.遺傳學試題庫，2001年北京市教學成果二等獎（第4完成人）

6.雲南地方稻種資源特徵特性地理分布系統及圖集研製， 2000年雲南省科技進步三等獎（第2完成人）

7.中國栽培稻的起源與演化，1998年教育部科技進步一等獎（第14完成人）

學術成果

課題項目

主要承擔國家支撐計畫、國家轉基因專項、國家自然科學基金和十三五重點研發計畫等項目，目前主持的主要科研項目有：

國家“863”課題《旱稻分子標記輔助育種》（2004-2005）；

“973”課題《水稻套用核心種質構建和功能基因多樣性》（2004-2009）；

國家“十五”攻關《磷高效、抗旱材料選育及其遺傳分析》（2004-2006）；

國家自然科學基金《水稻穗期耐冷基因的精細定位與克隆》（2006-2008）；

教育部博士點基金《水、旱稻花期耐旱基因表達規律研究》（2004-2006）

發表論文

發表論文200餘篇，其中，SCI收錄論文60餘篇。擇選部分發表的SCI論文如下（#為同等貢獻作者，*為通訊作者）

1.Zhanying Zhang#, Jinjie Li#, Zuoshun Tang#, Hongliang Zhang, Xingming Sun, Jianping Yu, Guoxin Yao, Gangling Li, Haifeng Guo, Jilong Li, Huamao Wu, Hanguang Huang, Yawen Xu, Zhigang Yin, Yanhua Qi, Rongfeng Huang, Weicai Yang and Zichao Li*.Gnp4/LAX2, a RAWUL Protein, Modulates Grain Length by Interfering withOsIAA3-OsARF25Interaction in Rice. Journal of Experimental Botany, 2018, 20(69):4723-4737, doi:10.1093/jxb/ery256

2.Yan Zhao#, Hongliang Zhang#, Jianlong Xu#, Conghui Jiang, Zhigang Yin, Haiyan Xiong, Jianyin Xie, Xueqiang Wang, Xiaoyang Zhu, Yang Li, Weipeng Zhao, Muhammad Abdul Rehman Rashid, Jinjie Li, Wensheng Wang, Binying Fu, Guoyou Ye, Yan Guo, Zhiqiang Hu, Zhikang Li* & Zichao Li*. Loci and natural alleles underlying robust roots and adaptive domestication of upland ecotype rice in aerobic conditions, PLoS Genet, 2018,14(8): e1007521.

3.Haiyan Xiong#, Jianping Yu#, Jinjie Li, Hongliang Zhang, Xin Wang, Pengli Liu, Jinli Miao,Yan Zhao, Chonghui Jiang, Zhigang Yin, Yang Li, Yan Guo, Binying Fu, Wensheng Wang, Zhikang Li, Jauhar Ali and Zichao Li*. Natural Variation in OsLG3 Increases Drought Tolerance in Rice by Inducing ROS Scavenging. Plant Physiology, 2018, Sep 2018, 178(1): 451-467;

4.Wensheng Wang#, Ramil Mauleon#, Zhiqiang Hu#, Dmytro Chebotarov#, Shuaishuai Tai#, Zhichao Wu#, Min Li#, Tianqing Zheng#, Roven Rommel Fuentes#, Fan Zhang#, Locedie Mansueto, Dario Copetti, Millicent Sanciangco, Kevin Christian Palis, Jianlong Xu, Chen Sun3, Binying Fu, Hongliang Zhang, Yongming Gao, Xiuqin Zhao, Fei Shen, Xiao Cui, Hong Yu, Zichao Li, Miaolin Chen, Jeffrey Detras, Yongli Zhou, Xinyuan Zhang, Yue Zhao, Dave Kudrna, Chunchao Wang, Rui Li, Ben Jia, Jinyuan Lu, Xianchang He, Zhaotong Dong, Jiabao Xu, Yanhong Li, Miao Wang, Jianxin Shi, Jing Li, Dabing Zhang, Seunghee Lee, Wushu Hu, Alexander Poliakov, Inna Dubchak, Victor Jun Ulat, Frances Nikki Borja, John Robert Mendoza, Jauhar Ali, Jing Li, Qiang Gao, Yongchao Niu, Zhen Yue, Ma. Elizabeth B. Naredo, Jayson Talag, Xueqiang Wang, Jinjie Li, Xiaodong Fang, Ye Yin, Jean-Christophe Glaszmann, Jianwei Zhang, Jiayang Li, Ruaraidh Sackville Hamilton, Rod A. Wing*, Jue Ruan*, Gengyun Zhang*, Chaochun Wei*, Nickolai Alexandrov*, Kenneth L. McNally*, Zhikang Li* & Hei Leung. Genomic variation in 3,010 diverse accessions of Asian cultivated rice, Nature, 2018,volume 557: 43-49

5.Jianping Yu#, Jinli Miao#, Zhanying Zhang, Haiyan Xiong, Xiaoyang Zhu, Xingming Sun, Yinghua Pan, Yuntao Liang, Qiang Zhang, M.A.R. Rashid, Jinjie Li1, Hongliang Zhang*, Zichao Li*. Alternativesplicing of OsLG3b controls grain length and yield in japonica rice. Plant Biotechnology Journal, 2018, 16(9): 1667–1678. DOI: 10.1111/pbi.12903

6.Xingming Sun#, Zhanying Zhang#, Chao Chen#, Wei Wu, Nannan Ren, Conghui Jiang, Jianping Yu, Yan Zhao, Xiaoming Zheng, Qingwen Yang, Hongliang Zhang, Jinjie Li and Zichao Li*.The C-S-A gene system regulates hull pigmentation and reveals evolution of anthocyanin biosynthesis pathway in rice, Journal of Experimental Botany, 2018, 69(7): 1485–1498 (10.1093/jxb/ery001)

7.Jinjie Li, Xiao Guo, Minghui Zhang, Xin Wang, Yan Zhao, Zhigang Yin, Haiyan Xiong, Hongliang Zhang, Elena Todorovska, Zichao Li*. OsERF71 acts as a transcription factor and confers drought and salinity tolerance via modulating ABA signaling and proline biosynthesis under stresses. Plant Science,2018, 270: 131–139,

8.Yan Zhao#, Weipeng Zhao#, Conghui Jiang#, Elena Georgieva Todorovska, Xiaoning Wang, Haiyang Xiong, Zhigang Yin, Yanfa Chen, Xin Wang, Jianyin Xie, Rashid Muhammad Abdul Rehman, Hongliang Zhang, Jinjie Li*, Zichao Li*. Genetic architecture and two genes OsML1 and OsML2 for deep-sowing tolerance were revealed by Non-Syn GWAS, Frontiers in Plant Scicence, 2018, 9(3), DOI: 10.3389/ fpls.2018.00332

9.Fengmei Li, Jianyin Xie, Xiaoyang Zhu, Xueqiang Wang, Yan Zhao, Xiaoqian Ma, Zhanying Zhang, Muhammad A. R. Rashid, Zhifang Zhang, Linran Zhi, Shuyang Zhang, Jinjie Li, Zichao Li and Hongliang Zhang* . Genetic Basis Underlying Correlations Among Growth Duration and Yield Traits Revealed by GWAS in Rice (Oryza sativa L.). FRONTIERS IN PLANT SCIENCE, 2018, 9(5): doi: 10.3389/fpls.2018.00650

10.Jilong Li#, Yinghua Pan#, Haifeng Guo, Lei Zhou, Shuming Yang, Zhanying Zhang, Jiazhen Yang, Hongliang Zhang, Jinjie Li, Yawen Zeng*, Zichao Li*. Fine mapping of QTL qCTB10-2 that confers cold tolerance at the booting stage in rice. Theor Appl Genet, 2018, 131:157–166, (DOI 10.1007/s00122-017-2992-3)

11.Zhanying Zhang#, Jinjie Li#, Yinghua Pan#, Jilong Li#, Lei Zhou#, Hongli Shi#, Yawen Zeng, Haifeng Guo, Shuming Yang, Weiwei Zheng, Jianping Yu, Xingming Sun, Gangling Li, Yanglin Ding, Liang Ma, Shiquan Shen, Luyuan Dai, Hongliang Zhang, Shuhua Yang, Yan Guo, Zichao Li*. Natural variation in CTB4a enhances rice adaptation to cold habitats, Nature Communications, 2017, 8, 14788, DOI: 10.1038/ncomms14788

12.Jianping Yu#, Haiyan Xiong#, Xiaoyang Zhu#, Hongliang Zhang, Huihui Li, Jinli Miao, Wensheng Wang, Zuoshun Tang, Zhanying Zhang, Guoxin Yao, Qiang Zhang, Yinghua Pan, Xin Wang, M.A.R. Rashid, Jinjie Li, Yongmin Gao, Zhikang Li, Weicai Yang, Xiangdong Fu, Zichao Li*. OsLG3 contributing to rice grain length and yield was mined by Ho-LAMap, BMC Biology, 2017, DOI : 10.1186/s12915-017-0365-7

13.Jinjie Li, Yang Li, Zhigang Yin, Jihong Jiang, Minghui Zhang, Xiao Guo, Zhujia Ye, Yan Zhao, Haiyan Xiong, Zhanying Zhang, Hongliang Zhang, Gynheung An, Nam-Chon Paek, Jauhar Ali, Zichao Li*. Overexpression of OsASR5 enhances drought tolerance by reducing water loss in Oryza sativa L. and Arabidopsis, Plant Biotechnology Journal, 2017, 15, pp. 183–196, doi: 10.1111/pbi.12601

14.Ben Li#, Yanpei Zhang#, Jinjie Li, Guoxin Yao, Huiqiao Pan, Guanglong Hu, Chao Chen, Hongliang Zhang, Zichao Li*. Fine mapping of two additive effect genes for awn development in rice (Oryza sativa L.), PLOS ONE, 2016，11(8): e0160792. doi: 10.1371/journal.pone. 0160792

15.Muhammad Abdul Rehman Rashid, Yan Zhao, Hongliang Zhang, Jinjie Li, and Zichao Li*. Nucleotide diversity, natural variation, and evolution of Flexible culm-1 and Strong culm-2 lodging resistance genes in rice, Genome, 2016,59: 473-483

16.Elsheikh Y M Ahmed, ZHANG Yan-pei, YU Jian-ping, Rashid M A Rehman, ZHANG Zhan-ying, ZHANG Hong-liang, LI Jin-jie, LI Zi-chao* . Mapping of three QTLs for seed setting and analysis on the candidate gene for qSS-1 in rice (Oryza sativa L.). Journal of Integrative Agriculture, 2016, 15(4): 735-743

17.Yinghua Pan#, Hongliang Zhang#, Dongling Zhang, Jinjie Li, Haiyan Xiong,Jianping Yu, Jilong Li, Muhammad Abdul Rehman Rashid, Gangling Li, Xiaoding Ma, Guilan Cao, Longzhi Han*, Zichao Li*. Genetic analysis of cold tolerance at the germination and booting stages in rice by association mapping. PLOS ONE, 2015, 10(3): e0120590.

18.Haiyan Xiong#, Jinjie Li#, Pengli Liu, Yan Zhao, Xiao Guo, Yang Li, Hongliang Zhang, Jauhar Ali, Zichao Li*. Overexpression of OsMYB48-1, a novel MYB-related transcription factor, enhances drought and salt tolerance in rice. PLOS ONE, 2014,9(3): e92913

19.Choon-Tak Kwon, Soo-Cheul Yoo, Bon-Hyuk Koo, Sung-Hwan Cho1,Joon-Woo Park, Zhanying Zhang, Jinjie Li, Zichao Li & Nam-Chonpaek*. Natural variation in early flowering1 contributes to early flowering in japonica rice under long days. Plant Cell and Enviornment. 2014, 37(1): 101-112

20.Bon-Hyuk Koo, Soo-Cheul Yoo, Joon-Woo Park, Choon-Tak Kwon, Byoung-Doo Lee, Gynheung An, Zhanying Zhang, Jinjie Li, Zichao Li & Nam-Chonpaek*. Natural variation in OsPRR37 regulates heading date and contributes to rice cultivation at a wide range of latitudes. Molecular Plant, 2013, 6(6): 1877-1888

21.Xin Wei, Wei-Hua Qiao, You-Tao Chen, Rong-Sheng Wang, Li-Rong Cao, Wan-Xia Zhang, Nan-Nan Yuan, Zi-Chao Li, Han-Lai Zeng*, Qing-Wen Yang*. Domestication and geographic origin of Oryza sativa in China: insights from multilocus analysis of nucleotide variation of O. sativa and O. rufipogon. Molecular Ecology, 2012, 21( 20):5073-5087

22.Junzhi Duan#, Minghui Zhang#, Hongliang Zhang, Haiyan Xiong, Pengli Liu, Jauhar Ali, Jinjie Li* and Zichao Li*. OsMIOX, a myo-inositol oxygenase gene, improves drought tolerance through scavenging of reactive oxygen species in rice (Oryza sativa L.). Plant Science, 2012,196:143-151

23.Hongliang Zhang, Dongling Zhang, Meixing Wang, Junli Sun, Yongwen Qi, Xinghua Wei, Longzhi Han, Zichao Li*. Core Collection and Mini Core Collection of Oryza sativa L. in China. Theor Appl Genet, 2011，122(1): 49-61

24.Junzhou Li, Yan Xie, Hongliang Zhang, Guanglong Hu, Anyong Dai, Lifeng Liu, Ping Mu, Yanying Qu, Zichao Li*. Development of upland rice introgression lines and QTL identification of root traits under different water regimes. Journal of Genetics and Genomics, 2011, 38(12): 547-556

25.Zhanying Zhang#, Guoxin Yao#, Jinjie Li#, Hongliang Zhang, Huijing Dou, Hongli Shi, Xingming Sun, Zichao Li*. Fine Mapping and Cloning of the Grain Number Per-panicle Gene (Gnp4) on Chromosome 4 in Rice (Oryza sativa L.). Agricultural Science in China. 2011,10(12)：1825-1833

26.Lei Zhou, Yawen Zeng, Weiwei Zheng, Bo Tang, Shuming Yang, Hongliang Zhang, Jinjie Li, Zichao Li*. Fine mapping a QTL, qCTB7, for cold tolerance at the booting stage on rice chromosome 7 using a near-isogenic line. Theor Appl Genet, 2010, 121: 893-905

27.Dongling Zhang, Hongliang Zhang*, Meixing Wang, Yongwen Qi, Junli Sun, Fengmei Wang, Xinghua Wei, Longzhi Han, Zongen Qiu, Shengxiang Tang, Xiangkun Wang, Zichao Li*, Genetic Structure and Differentiation of Oryza sativa L. in China Revealed by Microsatellites, Theor Appl Genet, 2009, 119: 1105-1117

28.Junzhou Li, Yan Xie, Anyong Dai, Lifeng Liu, Zichao Li*. Root and shoot traits responses to phosphorus deficiency and QTL analysis at seedling stage using introgression lines of rice. Journal of Genetics and Genomics, 2009, 36(3): 173-183

29.Meixing Wang#, Hongliang Zhang#, Dongling Zhang, Yongwen Qi, Zhilan Fan, Daoyuan Li, Dajian Pan, Yongsheng Cao, Zongen Qiu, Ping Yu, Qingwen Yang, Xiangkun Wang, Zichao Li*. Genetic Structure of Oryza rufipogon Griff. in China. Hereidity, 2008, 101：527-535

30.Lifeng Liu, Ping Mu, Xueqin Li, Yanying Qu,Yi Wang & Zichao Li* Localization of QTL for Basal Root Thickness in japonica Rice and Effect of Marker-Assisted Selection for a Major QTL. Euphytica, 2008, 164：729-737

31.Yanying Qu#, Ping Mu#, Hongliang Zhang, Yuxiu Tian, Feng Wen, Yiwu Chen, Zichao Li*， Genetic Analysis and QTL Mapping for Root Morphological Traits at Different Growth Stages in Rice, Genetica, 2008, 133:187-200

32.Liming Xu#, Lei Zhou#, Yawen Zeng#, Fengmei Wang, Hongliang Zhang, Shiquan Shen, Zichao Li*. Identification and mapping of Quantitative Trait Loci for cold tolerance at the booting stage in a Japonica rice near-isogenic line. Plant Science, 2008, 174: 340-347

33.Haiguang Wang, Hongliang Zhang, Fenghua Gao, Zichao Li*. Comparison of gene expression between upland and lowland rice cultivars under water stress using cDNA microassay. Theor Appl Genet, 2007, 115: 1109-1126

34.Hongliang, Zhang, Junli Sun, Meixing Wang, Ping Yu, Da Zhang, Dengqun Liao, Yawen Zeng, Shiquan Shen, Xiangkun Wang，Zichao Li*. Genetic structure and phylogeography of Rice Landraces in Yunnan, China Revealed by SSR, GENOME，2007，50(1)：72-83

35.Zichao Li*, Ping Mu, Chunping Li, Hongliang Zhang, Zhikang Li, Xiangkun Wang. QTL mapping of the root traits in a double haploid population from a cross between upland and lowland japonica rice under three environments，Theor Appl Genet, 2005,110: 1244-1252

36.Chuanqing Sun, Xiangkun Wang, Zichao Li. Comparison of genetic diversity of common wild rice (O.rufipogon Griff.) and cultivated rice (O. sativa L.) using RFLP markers, Theor Appl Genet, 2001，102:157-162

37.Li Zichao*, Zhang Hongliang et al., Studies on sampling stratyges for establishment of core collection of rice landrace in Yunnan, China. Genetic resources and crop evolution, 2002，49（1）：67-74

發表著作

1.李自超主編，中國稻種資源及其核心種質的研究與利用，中國農業大學出版社，2013年5月

2.李自超等編譯，植物遺傳資源核心種質，農業出版社，2012年10月

3.李自超等編寫第二章，水稻種質資源的研究與利用，見：萬建民主編《中國水稻遺傳育種與品種系譜（1986-2005）》，科學出版社，2010年：24-79

發明專利

-	專利名稱	專利號	專利 類型	主要完成人	授權 時間
1	鑑定水稻秈粳的方法及其專用引物組合物	ZL201010291872.X	國家發明專利	李自超，張冬玲，張洪亮，王美興，王鳳梅，宋立瑩，馬占峰	2013
2	用於鑑別水稻粳亞種生態型的引物組合物及其套用	ZL201110271833.8	國家發明專利	同上	2013
3	用於鑑別水稻秈亞種生態型的引物組合物及其套用	申請號201110271841.2	國家發明專利	同上	2013
4	水稻抗旱相關轉錄因子OsERF62及其抗旱耐鹽套用	201310322313.6	國家發明專利	李自超，熊海燕，劉鵬麗，李金傑，張洪亮	2017
5	旱稻抗旱基因OsERF71的克隆及其育種套用	201310322576.5	國家發明專利	李自超，趙炎，李金傑，張洪亮，張明輝，郭蕭	2017
6	旱稻抗旱基因OsCOBL4及其編碼蛋白與套用	201310322634.4	國家發明專利	李自超，熊海燕，劉鵬麗，李金傑，張洪亮	2017
7	一種鑑定水稻孕穗期耐冷性的方法	201310429883.3	國家發明專利	李自超，潘英華 李金傑 余建平 李繼龍 李剛嶺 張洪亮	2017
8	一種篩選耐冷水稻品系的專用引物	201310428665.8	國家發明專利	李自超，潘英華，李繼龍，李金傑，張洪亮	2017