李春艷，女，教授、博士生導師，2008年博士畢業於湖南大學化學化工學院，現任職湘潭大學化學學院。2019年入選中國化學會“中國青年化學家元素周期表”汞元素代言人。研究方向為：有機小分子螢光探針的設計合成、納米螢光探針的構建、螢光探針在生化分析中的套用。
基本介紹
- 中文名：李春艷
- 國籍：中國
- 畢業院校：湖南大學
- 職業：高校教師
- 學位/學歷：博士
- 職稱：教授
個人簡歷,研究方向,科研成果,學術論文,發明專利,
個人簡歷
2017年-至今，湘潭大學化學學院，教授，博士生導師
2013-2014年，美國伊利諾伊大學香檳分校(UIUC)，訪問學者
2008年-至今，湘潭大學化學學院，教師
2005-2008年，湖南大學化學化工學院，博士
2002-2005年，湖南大學化學化工學院，碩士
1998-2002年，河南師範大學化學化工學院，本科
研究方向
有機小分子螢光探針的設計合成， 納米螢光探針的構建， 螢光探針在生化分析中的套用
科研成果
主持國家自然科學基金面上項目/青年項目、中國博士後科學基金面上項目/特別資助項目、湖南省自然科學基金、湖南省教育廳重點項目/優秀青年項目等課題。近年來在Analytical Chemistry，Chemical Communication，Biomaterials，ACS Applied Materials & Interfaces，ACS Sensors等國際刊物發表論文近60篇，其中IF＞5.0的論文40多篇，論文他引1700多次。獲授權發明專利10項。指導研究生多次獲得湖南省優秀碩士學位論文、研究生國家獎學金、湘潭大學“研究生校長獎”等榮譽。2019年入選中國化學會“中國青年化學家元素周期表”汞元素代言人，2013年入選首屆湘潭大學青年拔尖人才計畫，湘潭大學韶峰學者學術骨幹。
學術論文
[35] Wen-Xin Wang...Chun-Yan Li*. Monitoring the fluctuation of hydrogen peroxide in diabetes and its complications with a novel near-infrared fluorescent probe, Analytical Chemistry, 2021, 93, 3301-3307. (IF: 6.785)
[34] Wen-Li Jiang...Chun-Yan Li*. Construction of NIR and ratiometric fluorescent probe for monitoring carbon monoxide under oxidative stress in zebrafish, Analytical Chemistry, 2021, 93, 2510-2518. (IF: 6.785)
[33] Yang Tian...Chun-Yan Li*. NAD(P)H-triggered probe for dual-modal imaging during energy metabolism and novel strategy of enhanced photothermal therapy in tumor, Biomaterials, 2021, 271, 120736. (IF: 10.371)
[32] Wen-Xin Wang...Chun-Yan Li*. Real-time imaging of alkaline phosphatase activity of diabetes in mice via a near-infrared fluorescent probe, Chemical Communications, 2021, 57, 480-483. (IF: 5.996)
[31] Yang Tian...Chun-Yan Li*. Novel near-infrared fluorescence probe with large Stokes shift for monitoring CCl4-induced toxic hepatitis, Talanta, 2021, 223, 121720. (IF: 5.339)
[30] Yang Tian...Chun-Yan Li*. The construction of a near-infrared fluorescent probe with dual advantages for imaging carbon monoxide in cells and in vivo. Analyst, 2021, 146, 118-123. (IF: 3.978)
[29] Yang Tian...Chun-Yan Li*. Novel strategy for validating the existence and mechanism of the “gut-liver axis” in vivo by a hypoxia-sensitive NIR fluorescent probe, Analytical Chemistry, 2020, 92, 4244-4250. (IF: 6.785)
[28] Yi-Ting Zhao...Chun-Yan Li*. Near-infrared fluorescence MOF nanoprobe for adenosine triphosphate-guided imaging in colitis, ACS Applied Materials & Interfaces, 2020, 12, 47840-47847. (IF: 8.758)
[27] Wen-Xin Wang...Chun-Yan Li*. Near-infrared fluorescence probe with a large stokes shift for visualizing hydrogen peroxide in ulcerative colitis mice, Sensors and Actuators B: Chemical, 2020, 320, 128296. (IF: 7.100)
[26] Wen-Li Jiang...Chun-Yan Li*. A novel hepatocyte-targeting ratiometric fluorescent probe for imaging hydrogen peroxide in zebrafish, Sensors and Actuators B: Chemical, 2020, 313, 128054. (IF: 7.100)
[25] Yang Liu...Chun-Yan Li*. A near-infrared fluorescence probe with a large Stokes shift for detecting carbon monoxide in living cells and mice, Dyes and Pigments, 2020, 180, 108517. (IF: 4.613)
[24] Zun-Pan She...Chun-Yan Li*. A facile pH near-infrared fluorescence probe for the diagnosis of cancer in vivo, Dyes and Pigments, 2020, 179, 108402. (IF: 4.613)
[23] Yang Tian...Chun-Yan Li*. In-situ imaging of azoreductase activity in the acute and chronic ulcerative colitis mice by a near-infrared fluorescent probe. Analytical Chemistry, 2019, 91, 10901-10907. (IF: 6.785)
[22] Juan Ou-Yang...Chun-Yan Li*. Fluorescence-guided cancer diagnosis and surgery by a zero cross-talk ratiometric near-infrared γ-glutamyltranspeptidase fluorescent probe. Analytical Chemistry, 2019, 91, 1056-1063. (IF: 6.785)
[21] Wen-Li Jiang...Chun-Yan Li*. A hepatocyte-targeting near-infrared ratiometric fluorescent probe for monitoring peroxynitrite during drug-induced hepatotoxicity and its remediation. Chemical Communications, 2019, 55, 14307-14310. (IF: 5.996)
[20] Wen-Li Jiang,...Chun-Yan Li*. A rhodamine-deoxylactam based fluorescent probe for fast and selective detection of nitric oxide in living cells. Talanta, 2019, 197, 436-443. (IF: 5.339)
[19] Dong-Ye Zhou...Chun-Yan Li*. A ratiometric fluorescent probe for the detection of peroxynitrite with simple synthesis and large emission shift and its application in cells image. Dyes and Pigments, 2019, 161, 288-295. (IF: 4.613)
[18] Song-Jiao Li...Chun-Yan Li*. A dual-response fluorescent probe for the detection of viscosity and H2S and its application in studying their cross-talk influence in mitochondria. Analytical Chemistry, 2018, 90, 9418-9425. (IF: 6.785)
[17] Dong-Ye Zhou...Chun-Yan Li*. A ratiometric fluorescence probe for peroxynitrite prepared by denovo synthesis and its application in assessing mitochondrial oxidative stress status in cells and in vivo. Chemical Communications, 2018, 54, 11590-11593. (IF: 5.996)
[16] Song-Jiao Li...Chun-Yan Li*. Efficient two-photon fluorescent probe for imaging of nitric oxide during endoplasmic reticulum stress. ACS Sensors, 2018, 3, 2311-2319. (IF: 7.333)
[15] Juan Ou-Yang...Chun-Yan Li*. Detecting and imaging of γ-glutamytranspeptidase activity in serum, live cells and pathological tissues with a high signal stability probe by releasing a precipitating fluorochrome. ACS Sensors, 2018, 3, 1354-1361. (IF: 7.333)
[14] Juan Ou-Yang...Chun-Yan Li*. Two-photon fluorescence probe for precisely detecting endogenous H2S in lysosome by employing a dual lock system. Sensors and Actuators B: Chemical, 2018, 260, 264-273. (IF: 7.100)
[13] Juan Ou-Yang, Chun-Yan Li*... An infinite coordination polymer nanoparticles-based near-infrared fluorescent probe with high photostability for endogenous alkalinephosphatase in vivo. Sensors and Actuators B: Chemical, 2018, 255, 3355-3363. (IF: 7.100)
[12] Song-Jiao Li...Chun-Yan Li*. Mitochondria-targeted near-infrared fluorescent probe for the detection of carbon monoxide in vivo. Talanta, 2018, 188, 691-700. (IF: 5.339)
[11] Song-Jiao Li, Chun-Yan Li*... A facile and sensitive near-infrared fluorescence probe for the detection of endogenous alkaline phosphatase activity in vivo. Analytical Chemistry, 2017, 89, 6854-6860. (IF: 6.785)
[10] Kai-Yue Tan, Chun-Yan Li*... Real-time monitoring ATP in mitochondrion of living cells: a specific fluorescent probe for ATP by dual recognition sites. Analytical Chemistry, 2017, 89, 1749-1756. (IF: 6.785)
[9] Juan Ou-Yang, Chun-Yan Li*... A rhodamine-based fluorescent probe with high water solubility and its application in the detection of glutathione with unique specificity. Sensors and Actuators B: Chemical, 2017, 240, 1165-1173. (IF: 7.100)
[8] Song-Jiao Li, Ya-Jun Fu, Chun-Yan Li*... A near-infrared fluorescent probe based on BODIPY derivative with high quantum yield for selective detection of exogenous and endogenous cysteine in biological samples. Analytica Chimica Acta, 2017, 994, 73-81. (IF: 5.977)
[7] Ya-Jun Fu, Zhi Li, Chun-Yan Li*... Borondipyrrolemethene-based fluorescent probe for distinguishing cysteine from biological thiols and its application in cell image. Dyes and Pigments, 2017, 139, 381-387. (IF: 4.613)
[6] Jun-Ying Xie, Chun-Yan Li*... A near-infrared chemosensor for determination of trivalent aluminum ions in living cells and tissues. Dyes and Pigments, 2017, 136, 817-824. (IF: 4.613)
[5] Zhi Li, Juan Ou-Yang, Ya-Jun Fu, Chun-Yan Li*... A borondipyrrolemethene-based turn-on fluorescent probe for silver ion with high sensitivity and selectivity and its application in water samples and living cells. Tetrahedron Letters, 2017, 58, 3536-3540. (IF: 2.275)
[4] Jun-Ying Xie, Chun-Yan Li*... Near-infrared fluorescent probe with high quantum yield and its application in the selective detection of glutathione in living cells and tissues. Analytical Chemistry, 2016, 88, 9746-9752. (IF: 6.785)
[3] Dan Li, Chun-Yan Li*...Rhodamine-based chemosensor for fluorescence determination of trivalent chromium ion in living cells. Sensors and Actuators B: Chemical, 2016, 223, 705-712. (IF: 7.100)
[2] Yin-Shuang Wu, Chun-Yan Li*... Development of a simple pyrene-based ratiometric fluorescent chemosensor for copper ion in living cells. Sensors and Actuators B: Chemical, 2016, 222, 1226-1232. (IF: 7.100)
[1] Dan Li, Chun-Yan Li*... Rhodamine-based chemodosimeter for fluorescent determination of Hg2+ in 100% aqueous solution and in living cells. Analytica Chimica Acta, 2016, 934, 218-225. (IF: 5.977)
發明專利
[10] 基於脫氧羅丹明的一氧化氮螢光探針的製備和套用，專利號ZL201811120191.X
[9] 基於半花菁染料的過氧化亞硝基螢光探針的製備和套用，專利號ZL201810233068.2
[8] 一種近紅外鹼性磷酸酶螢光探針的製備方法和套用，專利號ZL201611230342.8
[7] 一種近紅外GSH螢光探針的製備方法和套用，專利號ZL201610321434.0
[6] 基於羅丹明的GSH水溶性螢光探針的製備方法和套用，專利號ZL201610821181.3
[5] 一種基於氟硼吡咯的Cys螢光探針的製備方法和套用，專利號ZL201610902695.1
[4] 一種定位線粒體的ATP螢光探針的製備及套用，專利號ZL201610929418.X
[3] 基於羅丹明水溶性汞離子螢光探針的製備方法和套用，專利號ZL201610250556.5
[2] 一種基於芘的銅離子比率型螢光探針及其製備方法和套用，專利號ZL201410846656.5
[1] 一種鉻離子比率型螢光探針及其製備方法和套用，專利號ZL201310322506.X
