個人信息
姓 名:李孟華
學 科:基因組生物學
簡歷
中國科學院動物研究所“百人計畫”引進海外傑出人才。2003年畢業於華中農業大學畜牧獸醫學院動物遺傳育種與繁殖專業,獲得博士學位;2003年-2008年任芬蘭農業食品科學研究院生物技術和食品研究部博士後研究員;2008年-2010年於
赫爾辛基大學生物和環境科學系從事博士後研究;2010年至2011年任芬蘭農業食品科學研究院生物技術和食品研究部首席研究員;2011年8月至今為中國科學院動物研究所教授、研究員。
2010年6月被授予
赫爾辛基大學副教授(Docent),並擔任BMC Research Notes副編輯(Associate Editor),Journal of Evolutionary Biology Research編輯組成員(Editorial Team member),芬蘭生物互作研究生院及芬蘭群體遺傳學研究生院博士生導師(指導或聯合指導多名碩士或博士研究生),歐盟第6,7研發框架計畫專家組(動物遺傳部)成員。
共發表30多篇SCI論文,其中第一作者或通訊作者20多篇,總計影響因子約82,共被SCI雜誌文章引用達300多次。作為第一主持人和課題組負責人,承擔了芬蘭科學院和芬蘭農業和森林部重點創新項目2項,並參與了多項歐盟和北歐科研合作項目,與世界上10多個國家的國際著名教授和研究人員建立了廣泛而深入的科研合作。
研究領域
家養及野生動物基因組生態適應性及其套用。
獲獎及榮譽
芬蘭國家電視廣播台電視頻道1(YLE/TV1)專題報導“關於中國地方家畜遺傳資源保護的狀況”的專訪。
2018年8月3日,國家自然科學基金委員會公布2018年度
國家傑出青年科學基金建議資助項目申請人名單,其中李孟華在2018年度國家傑出青年科學基金建議資助項目申請人名單內。
科研項目
中國科學院百人計畫經費,2011-2013
代表論著
(#為共同第一作者,*為通訊作者)
2016年度:
Ren X#. Yang GL#, Peng WF, Zhao YX, Zhang M, Chen ZH, Wu FA, Kantanen J, Shen M, Li M.-H.* (2016) A genome-wide association study identifies a genomic region for the polycerate phenotype in sheep (Ovis aries) Scientific Reports
Xiaoju Hu, Kisun Pokharel,Jaana Peippo, Nasser Ghanem, Ismael Zhaboyev, Juha Kantanen and Meng-Hua Li*. (2016)Identification and characterization of miRNAs in the ovaries of a highly prolific sheep breed
2015年度:
Lv F-H, Peng W-F, Yang J, Zhao Y-X, Li W-R, Liu M-J, Ma Y-H, Zhao Q-J, Yang G-L, Wang F, Li J-Q, Liu Y-G, Shen Z-Q, Zhao S-G, Hehua E, Gorkhali NA, Farhad Vahidi SM, Muladno M, Naqvi AN, Tabell J, Iso-Touru T, Bruford MW, Kantanen J, Han J-L*, Li M-H* (2015). Mitogenomic Meta-Analysis Identifies Two Phases of Migration in the History of Eastern Eurasian Sheep
封面文章
受到“Financial Times”,“Modern Farmer”和“ILRI”等媒體報導和點評
Jun Liu, Cuimin Wang, Dongli Fu, Xiaoju Hu, Xiangmo Xie, Pengfei Liu, Qiong Zhang and Meng-Hua Li* (2015) Phylogeography of Nanorana parkeri (Anura: Ranidae) on the Tibetan Plateau: effects of Plateau uplift and Quaternary climatic changes
中國科學院科研進展英文評述
Weimin Zhao, Yulian Mu, Lei Ma, Chen Wang, Zhonglin Tang, Shulin Yang, Rong Zhou, Xiaoju Hu, Meng-Hua Li* and Kui Li* (2015) Systematic identification and characterization of long intergenic non-coding RNAs in fetal porcine skeletal muscle development
Kisun Pokharel, Jaana Peippo, Göran Andersson, Meng-Hua Li*, Juha Kantanen (2015) Transcriptome profiling of Finnsheep ovaries during out-of-season breeding period
Kantanen J, Løvendahl P, Strandberg E, Eythorsdottir E, Li M.-H., Kettunen-Præbel A, Berg P, Meuwissen T. (2015) Utilization of farm animal genetic resources in a changing agro-ecological environment in the Nordic countries
2014年度:
Feng-Hua Lv, Saif Agha, Juha Kantanen, LiciaColli, Sylvie Stucki, James W. Kijas, Stéphane Joost, Meng-Hua Li*, Paolo Ajmone Marsan (2014) Adaptations to Climate-Mediated Selective Pressures in Sheep
封面文章
受到Science daily等媒體報導和點評
Ji Yang, Takahito Shikano, Meng-Hua Li*, Juha Merilä (2014) Genome-wide linkage disequilibrium in nine-spined stickleback
Yang J, Li M.-H.* (2014) A multi-omics integrated study deciphers biology of the rumen and lipid metabolism
特邀評述
Liu J., T. Shikano, T. Leinonen, J. M. Cano, M.-H. Li*, J. Merilä (2014) Identification of major and minor QTL for ecologically important morphological traits in three-spined sticklebacks (Gasterosteus aculeatus)
Shan L., Wu Q., Li Y., Shang H., Guo K., Wu J., Wei H., Zhao J., Yu J., Li M.-H.*(2014) Transcriptome profiling identifies differentially expressed genes in postnatal developing pituitary gland of miniature pig
Li M.-H.*, T. Tiirikka, J. Kantanen (2014) A genome-wide scan study identifies a single nucleotide substitution in ASIP associated with white versus non-white coat-colour variation in sheep (Ovisaries)
Zhang Min, Wei-Feng Peng, Guang-Li Yang, Feng-Hua Lv, Ming-Jun Liu, Wen-Rong Li, Yong-Gang Liu, Jin-Quan Li, Feng Wang, Zhi-Qiang Shen, Sheng-Guo Zhao, EEr Hehua, Nurbiy Marzanov, Maziek Murawski, Juha Kantanen and Meng-Hua Li (2014) Y chromosome haplotype diversity of domestic sheep (Ovis aries) in northern Eurasia
2011-2013年度:
Wang C., Hu X., Xie X., Liu P., Merilä J., Zhang Q. *, Li M.-H.* (2013) Isolation and characterization of 113 polymorphic microsatellite loci for the Tibetan frog (Nanoranaparkeri) using next generation sequencing
Li M.-H., A.Osva, J. Kantanen (2012) Integrating multidisciplinary data for the conservation of livestock biodiversity: a case study of the Yakutian cattle in Siberia, the far east of Russia
Li M. H.* and J. Merilä (2011) Population differences in levels of linkage disequilibrium in the wild
Li M.-H., I. Strandén, T. Tiirikka, M.-L. Sevón-Aimonen, J. Kantanen (2011) A comparison of approaches to estimate the inbreeding coefficient and pairwise relatedness using genomic and pedigree data in a sheep population
Cano J.M., M.-H. Li, Laurila A, Vilkki J, Merilä J. (2011) First-generation linkage map for the common frog Ranatemporaria reveals sex linkage group
Li M.-H.*, J. Kantanen, A. Michelson, U. Saarma (2011) Genetic components of grey cattle in Estonia as revealed by microsatellite analysis using two Bayesian clustering methods
Zerabruk M.#, Li M.-H. #, J. Kantanen, I. Olsaker, E. M. Ibeagha-Awemu, G. Erhardt, D. G. Bradley and O Vangen (2011) Genetic diversity and admixture of indigenous cattle breeds of North Ethiopia: implications to historical introgressions in the gateway region of cattle to Africa
Nair A., S. Kumar, S. George, S. Gopalan, M.-H. Li, E. Leder and J. Merilä (2011) Sixty two new microsatellite markers for an endemic frog Indiranabeddomii from the Western Ghats biodiversity hotspot
2001-2010年度:
Tapio, I., Tapio, M., M.-H. Li, Popov, R., Ivanova, Z., Kantanen, J (2010) Estimation of relatedness among non-pedigreed Yakutiancryo-bank bulls using molecular data: implications for conservation and breed management
Li M. H.* and J. Merilä (2010) Population differences in levels of linkage disequilibrium in the wild
Li M. H.* and J. Merilä (2010) Genetic evidence for male-biased dispersal in the Siberian jay (Perisoreus infaustus) based on autosomal and Z chromosomal markers
Li, M.H., Kantanen, J (2010) Genetic structure of Eurasian cattle (Bos taurus) based on microsatellites: clarification for their breed classification
Li, M.H., Iso-Touru, T., Lauren, H., Kantanen, J (2010) A microsatellite-based analysis for the detection of selection on BTA1 and BTA20 in northern Eurasian cattle (Bos taurus) populations
Li M. H.* and J. Merilä (2010) Avian Z-specific microsatellites map to pseudoautosomal or autosomal chromosomes in the Siberian jay (Perisoreus infaustus): insights into avian genome evolution from cross-species amplification tests
Li M.-H.* and J. Merilä(2010) Sex-specific population structure, natural selection, and linkage disequilibrium in a wild bird population as revealed by genome-wide microsatellite analyses
Li M.-H.*, and J. Merilä (2010) Extensive linkage disequilibrium in a wild bird population
Iso-Touru, T., J. Kantanen, M. H. Li, Z. Gizejewski and J.Vilkki (2009) Divergent evolution in cattle and pigs in the cytoplasmic domains of GHR and PRLR
Li M.-H.* K. Välimäki, M. Piha, T.Pakkala and J. Merilä (2009) Extrapair paternity and maternity in the three-toed woodpecker, Picoides tridactylus: insights from microsatellite-based parentage analysis
Li M.-H., I. Strandén, and J. Kantanen (2009) Genetic diversity and pedigree analysis of the Finnsheep breed
Jarri S., M.-H. Li*, and J. Merilä (2009) A first-generation microsatellite-based genetic linkage map of the Siberian jay (Perisoreusinfaustus): insights into avian genome evolution
Agha S. H., F. Pilla, S. Galal, I. Shaat, M. D’Andrea, S. Reale, A. Z. A. Abdelsalam, and M.-H. Li (2008) Genetic diversity in Egyptian and Italian goat breeds measured with microsatellite polymorphism
Li M.-H., I. Tapio, J. Vilkki, Z. Ivanova, T. Kiselyova, N. Marzanov, M. Cinkulov, S. Stojanovic, I. Ammosov, R. Popov, and J. Kantanen (2007) Genetic structure of cattle populations (Bostaurus) in northern Eurasia and the neighboring Near Eastern regions: implications for breeding strategies and conservation
封面文章
Li M.-H., M. Zerabruk, O. Vangen, I. Olsaker, and J. Kantanen (2007) Reduced genetic structure of north Ethiopian cattle revealed by Y-chromosome analysis
Li M.-H., T. Adamowicz, M. Switonski, I. Ammosov, Z. Ivanova, T. Kiselyova, R. Popov, and J. Kantanen (2006) Analysis of population differentiation in North Eurasian cattle (Bostaurus) using single nucleotide polymorphisms in three genes associated with production traits
Bennewitz J., J. Kantanen, I. Tapio, M.-H. Li, E. Kalm, J. Vilkki, I. Ammosov, Z. Ivanova, T. Kiselyova, R. Popov, and T. H. Meuwissen (2006) Estimation of breed contributions to present and future genetic diversity of 44 North Eurasian cattle breeds using core set diversity measures
Li M.-H., K. Li, J. Kantanen, Z. Feng, B. Fan, and S. H. Zhao (2006) Allelic variations in exon 2 of caprine MHC class II DRB3 gene in Chinese indigenous goats
Li M.-H., E. Nogovitsina, Z. Ivanova, G. Erhardt, J. Vilkki , R. Popov, I. Ammosov, T. Kiselyova, and J. Kantanen (2005) Genetic contributions of indigenous Yakutian cattle to two hybrid populations as revealed by microsatellite variation
Li, M.-H., K. Sternbauer, P. T. Haahr, and J. Kantanen (2005) Genetic components in contemporary Faroe Islands Cattle as revealed as microsatellite analysis
Li S. J., S. H, Yang, S. H. Zhao, B. Fan, M. Yu, H. S. Wang, M.-H. Li, B. Liu, T. A. Xiong, and K. Li (2004) Genetic diversity analyses of 10 indigenous Chinese pig populations based on 20 microsatellites
Li M.-H., S, H. Zhao, and K. Li (2004) Diversity of Chinese indigenous goat breeds: a conservation perspective – a review.
Mo D. L., B. Liu, Z. G. Wang, S. H. Zhao, M. Yu, B. Fan, M.-H. Li, T. A. Xiong, M. Yu, and K. Li (2003) Genetic variation and genetic relationship of seventeen Chinese indigenous pig breeds using ten serum protein loci
Yang S. L, Z. G Wang, B. Liu, G. X. Zhang, S. H. Zhao, M. Yu, B. Fan, M.-H. Li, and K. Li (2003) Genetic variation and relationships of eighteen Chinese indigenous pig breeds
Fan B., Z. G. Wang, Y. J. Li, X. L. Zhao, B. Liu, S. H. Zhao, M Yu, M.-H. Li, S. L. Chen, T.A. Xiong, and K. Li (2002) Genetic variation analysis within and among Chinese indigenous swine populations using microsatellite markers
Li M.-H., S. H. Zhao, C. Bian, H. S. Wang, H. Wei, B.Liu, M. Yu, B. Fan, S. L. Chen, M. J. Zhu, T. A. Xiong, and K. Li (2002) Genetic relationships among twelve indigenous Chinese goat populations based on microsatellite analysis
Chen S. L., M.-H. Li, Y. J. Li, S.H. Zhao, C. Z. Yu, M. Yu, B. Fan, T. A. Xiong, and K. Li (2001) RAPD variation and genetic distances among Tibetan, Inner Mongolia and Liaoning Cashmere goats
Sakha Ynaga. Cattle of the Yakuts (Granberg L., J. Kantanen& K. Soinieds). Finnish Academy of Science and Letters