遺傳工程國家重點實驗室和復旦大學生物醫學研究院雙聘PI，國家863生物醫藥高技術項目終審評審。上海市免疫學會常務理事，美國雜誌Regional Editor,西南大學客藉兼職教授。
基本介紹
- 中文名：朱乃碩
- 國籍：中國
- 職業：博士導師，教授
- 性別：男
人物經歷,主要研究方向,所獲榮譽,代表性成果,
人物經歷
1983年於南京醫科大學獲醫學士，1991年於上海交通大學獲生物化學碩士，1994 年於上海交通大學獲分子生物學博士，受教於上海生化與分子生物學會前理事長陳詩書教授，2001年於香港大學醫學院微生物系訪問學者。
主要研究方向
分子生物學、免疫學，疾病發生的分子機理及表觀遺傳學干預和疫苗及免疫基因工程；免疫耐受誘導和免疫增效，腫瘤生長和轉移的基因調控，基因檢測診斷，器官移植免疫排斥機理和抗排斥研究，病毒免疫耐受形成機理及抗病毒研究。
所獲榮譽
曾獲中國高校科技進步二等獎兩次，中國科協首屆青年生命科學大會優秀科技論文獎，獲上海第五屆青年優秀科技論文獎，衛生廳科技進步二等獎，《免疫學導論》獲教育部優秀教材二等獎。申請發明專利16項, 獲專利授權8項，其中3項專利分別獲得美國、日本和印度授權。
代表性成果
1.Zheng H, Du G, Zhao R , Tang B, Zhu N * (2009),Enhanced Allogeneic Skin Graft Survival using sCD95L、sCD152、IL-10 and TGF-β in Combination and Comparison with CsA. Clinical and Experimental Dermatology, 34:721-727.2.Chongwen Zhang，Li Gong，Yuanyuan Chen, Xiaohua Wang, Sibo Zhu, Ding Li, Yun Pang,Yue Yin, Xi Liu, Naishuo Zhu * (2013),A human-derived protein SBP (HBsAg-binding protein) can bind to hepatitis B virus surface antigen (HBsAg) and enhance the immune response to hepatitis B virus (HBV) vaccine,Molecular Immunology. 53: 60-713.3.Xiaobo Hu, Rui Liu, Naishuo Zhu *（2013）Enhancement of humoral and cellular immune responses by monophosphoryl lipid A (MPLA) as an adjuvant to the rabies vaccine in BALB/c mice. Immunobiology. 218(2013):1524-1528.4. L. Xirong, L. Rui, Y. Xiaoli, H. Qiuyan, T. Bikui, Z. Sibo, and Z. Naishuo * (2014) Hepatitis B virus can be inhibited by DNAmMethyltransferase 3a via specific Zinc-Finger-induced methylation of the X promoter. Biochemistry (Moscow). 2014 (2) 13–249. 5. Jiansheng Huang,Xirong Li, Naishuo Zhu * (2012),Genetic characteristics of one highly multi-drugresistantstrain of Klebsiella ozaenae.Journal of Medical Microbiology, 61（9）1303-05,DOI:jmm.0.044115-0.6. Zhao R, Tang B Zhu NS* NLS-dependent and insufficient nuclear localization of XAGE-1 splice variants. Oncology Reports, （2011）. 25(4):1083-1089.7. Xu Xiulin; Yang Yujing; Zhu Naishuo*.(2009). Characteristics and molecular mechanism of adhesion proteins on reused hemodialysis membranes. Blood purification 27(4):321-9.8. Liu Yang; Zhu Qiyun; Zhu Naishuo*.(2008).Recent duplication and positive selection of the GAGE gene family. Genetica 133(1):31-5.9. Yang Liu, Qiyun Zhu,Naishuo Zhu*.(2007)Rapid HLA-DR fluorotyping based on melting curve analysis. Immunological Investigations 36（4）:507 -521.10. Zhu NS*, Gao Neng, Wang YingMing, Wang, XiaoHua, Yang Yi. (2004). Expression of the negative co-stimulatory ligand sCD152 in the yeast, Pichia pastoris, and its regulation of antigen specific immune responses. International Immunopharmacology. 4(1):139-148.11. Zhu NS*, Yang JL, Wang YM, Guan XF. (2003). Study of the difference of high and low metastasis, cell line's gene expression map and metastasis-related genes of adenoid cystic carcinoma. Experiment Molecular Medicine.35 (4): 243-248.12. Yang JL, Zhu NS*, Wang Y, Guan XF, Zheng ZX.(2004). Protein and mRNA characterization in high and low metastasis adenoid cysticcarcinoma cell lines. Molecular Biology Reports. 31:241-248.
