於明明

於明明

於明明，男，博士，鄭州大學化學與分子工程學院教授，碩士生導師，校級青年骨幹教師。

基本介紹

人物經歷,學術成果,研究方向,研究課題,代表文章,授權專利,公開專利,榮譽稱號,

人物經歷

1998年畢業於吉林大學。2005年5月於中科院理化所獲博士學位。清華大學化學系博士後工作後，2007年到鄭州大學工作。先後被評為校級青年骨幹教師、省級青年骨幹教師。

學術成果

任職以來主持國家自然科學基金一項，參與一項，在Org. Lett.、Chem. Commun.、Inorg. Chem.、Langmuir、Anal. Chem.、J. Mater. Chem. C等雜誌上發表論文四十餘篇。2010年9月發表在Chem. Commun.的論文下載次數為當月該雜誌的第三。2012年9月發表在New J. Chem.的文章為當月該雜誌下載次數Top-Ten的第一。為Biosensors and Bioelectronics、Sensors and Actuators B、Analytica Chimica Acta、Dyes and Pigments等雜誌的審稿人。

研究方向

主要從事生物螢光分子探針和螢光高分子的研究。
生物螢光探針
研究具有高靈敏性、快速回響、高空間解析度的螢光小分子、納米複合物和生物高分子探針，探討探針的識別機制，用於生物體內一些重要生理過程生命相關的螢光成像。
螢光功能高分子材料
研究高分子的螢光回響、能量傳遞、生物模擬以及高分子結構與螢光相互作用的規律。這方面研究期望用於螢光離子捕獲、螢光染料以及生物標記與藥物輸運領域。

研究課題

鄭州大學化學與分子工程學院“青年學術骨幹”教師基金
國家自然科學基金“具有雙識別協同作用的鋅、銅離子螢光分子探針”（項目批准號：50903075）
中國科學院光化學轉換與功能材料重點實驗室開放課題“人造捕光天線的分子設計與套用”
橫向課題“新型顯色離子吸附劑的研製”

代表文章

1.Li, Z.X.;Liu, H.X.;Li, H.X.;Tsou, Y.H.; Gao, Y.L.; Xu*, X.Y.; Du, W.W.;Wei, L.H.;Yu, M.M.* Lysosome-targeting NIR Ratiometric Luminecent Upcoversion Nanoprobe toward Arginine. Sens. Actuators B,2019,280, 94–101.
2.Song, H.H.; Du, W.W.; Liu, C.X.; Li, Z.X.*; Zhang, H.Y.*; Wei, L.H.;Yu, M.M.*Self-Assembled Micellar Nanosensor toward pH with high photo-stability and its application in living cells. Sens. Actuators B,2018,273, 927–934.
3.Ban, Y.; Wang, R.H.; Li, Y.; An, Z.;Yu, M.M.*; Fang, C.J.*; Wei, L.; Li, Z.X. Mitochondria-targeted ratiometric fluorescent detection of hydrazine with fast response time. New J. Chem.,2018,42, 2030?2035.
4.Shi, B. J.;He,Y. Y.;Zhang, P. P.;Wang, Y. L.;Yu, M. M.*;Zhang, H. Y.*;Wei,L. H.;Li, Z. X.*Turn on fluorescent detection of hydrazine with a 1,8-naphthalimde derivative. Dyes Pigments,2017, 147, 152–159.
5.He,Y. Y.;Li, Z. X.*; Jia, Q. Y.;Shi, B. J.;Zhang, H. Y.*;Wei,L. H.;Yu, M. M.*Ratiometric fluorescent detection of acidic pH in lysosome with carbon nanodots. Chin. Chem. Lett.,2017,28(10), 1969-1974.
6.Li, H. X; Dong, H.;Yu, M. M.; Liu, C. X.;Li, Z. X.; Wei,L. H.;Sun, L. D.; Zhang, H. Y. NIR ratiometric luminescence detection of pH fluctuation in living cells with hemicyanine derivative-assembled upconversion nanophosphors. Anal. Chem.,2017,89, 8863?8869.
7.Shi, B. J.; Qi, S. J.;Yu, M. M.;Liu, C. X.;Li, Z. X.; Wei,L. H.;Ni, Z. H. Colorimetric and fluorescent detection of hydrazine with high sensitivity and excellent selectivity. Spectrochim. Acta A,2018,188, 208–212.
8.He,Y. Y.;Li, Z. X.;Shi, B. J.;An, Z.;Yu, M. M.;Wei,L. H.;Ni, Z. H.A new near-infrared ratiometric fluorescent probe for hydrazine. RSC Adv.,2017,7, 25634–25639.
9.Yu, M. M.*;Du, W. W.;Li, H. X.; Zhang, H. Y.*;Li, Z. X.* Near-infrared ratiometric fluorescent detection of arginine in lysosome with a new hemicyanine derivative. Biosens. Bioelectron.,2017,92, 385–389.
10.An, Z.;Li, Z. X.*;He, Y.; Shi, B.; Wei, L.;Yu, M. M.*Ratiometric luminescent detection of hydrazine with a carbon dots-hemicyanine nanohybrid system. RSC Adv.,2017,7, 10875–10880.
11.Li, Z. X.;*Zhang, W. Y.;Liu, C. X.;Yu, M. M.*;Zhang, H. Y.*;Guo,L.;Wei,L. H. A colorimetric and ratiometric fluorescent probe for hydrazine and its application in living cells with low dark toxicity. Sens. Actuators B,2017,241, 665–671.
12.Shi, B. J.; Gao, Y. L.;Liu, C. X.;Feng, W. Li, Z. X.;Wei,L. H.;Yu, M. M.*A ratiometric fluorescent sensor for pH fluctuation and its application in living cells with low dark toxicity. Dyes Pigments,2017,136, 522–528.
13.Li, Z. X.;Li, H. X.;Shi, C. X.;Yu, M. M.;Wei,L. H.;Ni Z. H. Nanomolar colorimetric quantitative detection of Fe3+and PPi with high selectivity. Spectrochim. Acta A,2016,159, 249–253.
14.Yu, M. M.*,Du, W. W.;Zhou, W.; Li, H. X.;Liu, C. X.;Wei,L. H.;Li, Z. X.*; Zhang, H. Y.A 1,8-naphthalimide-based chemosensor with an off-on fluorescence and lifetime imaging responsefor intracellular Cr3+and further for S2?. Dyes Pigments,2016,126, 279–285.
15.Li, Z. X.*; Li, H. X.; Shi, C. X.;Zhang, W. Y.;Zhou, W.;Wei,L. H.;Yu, M. M.* Naked-eye-based highly selective sensing of Fe3+and further for PPi withnano copolymer Film. Sens. Actuators B,2016,226, 127–134.
16.Yu, M. M.*;Xu, J.; Peng, C.; Li, Z. X.; Liu, C. X.; Wei,L. H. A novel colorimetric and fluorescent probe for detecting fluoride anions: from water and toothpaste samples. Tetrahedron,2016, 72, 273–278.
17.Xu, L. J.; Liang, X. Y.; Zhang, L.; Wu, J. B.;Li, Z. X.;Yu, M. M.*;Wei,L. H.* The vesicle formation ofβ-CD and AD self-assembly of dumbbell-shaped amphiphilic triblock copolymer. Colloid Polym. Sci.,2016, 294, 145–155.
18.Zhang, W. Y.; Liu, X. J.; Zhang, H. Y.; Feng, C. C.; Liu, C. X.;Yu, M. M.*;Wei,L. H.;Li, Z. X.* A fluorescent probe for benzenethiols and its application on test paper, in water samples and living cells. J. Mater. Chem. C,2015,3, 8248–8254.
19.Liu, C. X.; Shi, C. X.; Li, H. X.; Du, W. W.; Li, Z. X.*; Wei,L. H.;Yu, M. M.* Nanomolar fluorescent quantitative detection of formaldehyde with a 8-hydroxyquinoline derivative in aqueous solution and electrospun nanofibers. Sens. Actuators B,2015,219, 185–191.
20.Li, Z. X.*; Zhang, W. Y.;Liu, X. J.;Liu, C. X.;Yu,M. M.*;Wei, L. H.* Naked-eye-based selective detection of pyrophosphate with Zn2+complex in aqueous solution and electrospun nanofibers. RSC Adv.,2015,5, 25229–25235.
21.Liu, C. X.; Xu, J.; Yang, F.; Zhou, W.;Li, Z. X.*;Wei, L. H.;Yu,M. M.*Nanomolar Cu2+and F–naked-eye detection with a 1,8-naphthalimide-based colorimetric probe. Sens. Actuators B,2015,212, 364–370.
22.Du, W. W.; Xu, J.; Li, H. X.; Feng, C. C.;Yu,M. M.*;Li Z. X.;*Wei L. H. Naked-eye and fluorescent detection of basic pH and F?with a 1,8-naphthalimide-based multifunctional probe. RSC Adv.,2015,5, 15077–15083.
23.Zhou, W.; Dong, H.; Yan, H.; Shi, C. X.;Yu, M. M.*;Wei, L. H.;Li, Z. X.*HCHO-reactive molecule with dual-emission-enhancement property for quantitatively detecting HCHO in near 100% water solution. Sens. Actuators B,2015,209, 664–669.
24.Liu, X. J.; Zhang, W.Y.; Li, C. X.; Zhou, W.; Li, Z. X.*;Yu, M. M.*;Wei, L. H.Nanomolar detection of Hcy, GSH and Cys in aqueous solution, test paper and living cells. RSC Adv.,2015,5, 4941–4946.
25.Li, Z. X.*; Liu, X. J.; Zhao, W. Y.; Wang, S.; Zhou, W.; Wei, L. H.;Yu, M. M.* Naked-eye detection of C1–C4 alcohols based on ground-state intramolecular proton transfer. Anal. Chem.,2014,86, 2521?2525.
26.Su, Z.; Huang, S. S.; He, M.; Dong, C. F.; Wu, L. Z.; Li, C. H.; Liu, J. X.;Yu, M. M.*; Wei, L. H.* Synthesis and antibacterial performance of silver bromide and silver nanoparticles J. Nanoeng. and Nanomanuf.2014, 4(4), 330?335.
27.Liu, X. J.; Chen, M. X.; Liu, Z. P.;Yu, M. M.*; Wei, L. H.; Li, Z. X.* Synthesis of 1,8-naphthyridine and BF2-based isomers and their application in fluorogenic sensing Cd2+ Tetrahedron2014,70, 658?663.
28.Yu, M. M.*; Yuan, R. L.; Shi, C. X.; Zhou, W.; Wei, L. H.; Li, Z. X.*1,8-Naphthyridine and 8-hydroxyquinoline modified Rhodamine B derivatives: “Turn-on” fluorescent and colorimetric sensors for Al3+and Cu2+ Dyes Pigments2013,99, 887?894.
29.Li, X. Y.;Yu, M. M.; Liu, X. J.; Yang, F. L.;Wei, L. H.;Li, Z. X.*A dual-mode ratiometric and on?off fluorescent Al3+/Cu2+-chemosensor and the detection of F?/Al3+with ‘in situ’ prepared Al3+/Cu2+complex in aqueous solution. New J. Chem.2013,37, 2257-2260.
30.Li, H. Q.; Li, Z. X.*; Wu, L. Z.; Zhang, Y. N.;Yu, M. M.*;Wei, L. H.*Constructing metal nanoparticle multilayers with polyphenylene dendrimer/gold nanoparticlesvia “click” chemistry. Langmuir 2013,29, 3943?3949.
31.Li, Z. X.; Zhou, W.; Zhang, L. F.; Yuan, R. L.; Liu, X. J.; Wei, L. H.;Yu, M. M.*Highly selective ratiometric fluorescent detection of Fe3+with a polyphenyl Derivative. J. Lumin.2013,136, 141?144.
32.Li, Z. X.; Zhao, W. Y.; Li, X. Y.; Zhu, Y. Y.; Liu, C. M.; Wang, L. N.;Yu, M. M.*; Wei, L. H.; Tang, M. S.; Zhang, H. Y.* 1,8-Naphthyridine-derived Ni2+/Cu2+-selective fluorescent chemosensor with different charge transfer processses. Inorg. Chem.2012,51, 12444-12449.
33.Wang, L. N.,Yu, M. M.*, Liu, Z. T., Zhao, W. Y., Li, Z. X.,*Ni, Z. H., Li, C. C., Wei, L. H.*A visible light excitable “on-off” and “green-red” fluorescent chemodosimeter for Ni2+/Pb2+New J. Chem.2012,36, 2176–2179.
34.Li, Z. X.;Zhang, L. F.;Li, X. Y.;Guo, Y. K.; Ni, Z. H.; Chen, J. H.;Wei, L. H.;Yu, M. M.*A fluorescent color/intensity changedchemosensorfor Fe3+by photo-induced electron transfer (PET) inhibition of fluoranthene derivative. Dyes Pigm.2012,94, 60–65.
35.Huiqiang Li, Zhanxian Li, Linzhi Wu, Fang Liu, Jie Zhou, Miao Luan,Mingming Yu*, Liuhe Wei* Water-Soluble Starlike Poly(acrylic acid) Graft Polymer: Preparation and Application as Templates for Silver Nanoclusters Polym. Bull.,2012,68, 2229–2242.
36.Zhanxian Li, Wanying Zhao, Yuna Zhang, Lifeng Zhang,Mingming Yu*, Jinxia Liu* and Hongyan Zhang*An “off-on” fluorescent chemosensor of selectivity to Cr3+and its application to MCF-7 cells Tetrahedron,2011, 67, 7096–7100.
37.Zhan-Xian Li,Li-Feng Zhang, Wan-Ying Zhao, Xiao-Ya Li, Yong-Kai Guo,Ming-Ming Yu*, Jin-Xia Liu*Fluoranthene-based pyridine as fluorescent chemosensor for Fe3+ Inorg. Chem. Commun.,2011,14, 1656–1658.
38.Zhanxian Li, Lifeng Zhang, Lina Wang, Yongkai Guo, Lianheng Cai,Mingming Yu,* Liuhe Wei*Highly Sensitive and Selective Fluorescent Sensor for Zn2+/Cu2+and NewApproach for Sensing Cu2+by Central Metal Displacement Chem. Commun.,2011, 47, 5798–5800.
39.Zhanxian Li,Mingming Yu,* Lifeng Zhang, Ming Yu, Jinxia Liu, Liuhe Wei,* and Hongyan Zhang*A “switching on” fluorescent chemodosimeter of selectivity to Zn2+and its application to MCF-7 cells Chem. Commun.,2010, 46, 7169–7171.
40.Ming Ming Yu, Xia Li, Miao Luan, Jun Na Gao, Qiu Zhi Shi,Ming Sheng Tang, Liu He Wei An improved synthesis of bis(cyclopentadienone) Chin. Chem. Lett.,2010, 21, 1157–1161.
41.Ming-Ming Yu, Zhan-Xian Li, Liu-He Wei, Dong-Hui Wei, Ming-Sheng Tang A 1,8-Naphthyridine-based Fluorescent Chemodosimeter for the Rapid Detection of Zn2+and Cu2+ Org. Lett.2008, 22(10), 5115–5118.
42.Ming-Ming Yu, Hui-Zhong Kou, Zhong-Hai Ni, Chong-Chao Zhao, Ai-Li Cui Synthesis and Study of Ferromagnetic μ1,1-Azido-Bridged Manganese(II) Dinuclear Complexes with S=5 and S = 5 × 2 2 Ground State Eur. J. Inorg. Chem.2007, 5670–5676.

授權專利

於明明、張文英、李占先、石彩霞、周婉、魏柳荷，一種高分子比色納米薄膜材料及其製備方法以及用於Fe3+和焦磷酸根檢測方面的套用。2015.05.26，中國，專利號：ZL201510292665.9
於明明、李海霞、嚴晗、周婉、李占先、魏柳荷，一種甲醛快速檢測試劑及其製備方法與套用。2016.11.02，中國，專利號：ZL201410500026.2
於明明、張文英、劉興江、周婉、李占先、魏柳荷，一種檢測焦磷酸根的納米纖維膜試條、製備方法及其套用。2015.11，中國，專利號：ZL201410402826.0
於明明、李占先、魏柳荷、劉興江，一種氟硼螢光衍生物、其製備方法及套用。2015.11，中國，專利號：ZL201310171197.0
於明明、喬鈺茜、李占先、魏柳荷、郭永開，2,4-二苯基-5,6-二吡啶基-苯酚及其製備。2015.6，中國，專利號：ZL201310518992.2
李占先、於明明、魏柳荷、劉興江、趙萬瑩、周婉，一種低級醇檢測探針、製備方法及套用。2015.4，中國，專利號：ZL201310198342.4
於明明、李占先、魏柳荷、張利鋒、趙萬瑩、王麗娜，苯衍生物金屬離子螢光探針及其套用。2014.4，中國，專利號：ZL201110169893.9
李占先、於明明、張利鋒、虞明、魏柳荷、劉金霞，一種檢測細胞內鋅離子的分子螢光開關及其套用。2013.4，中國，專利號：ZL201010181802.9。
李占先、於明明、魏柳荷、張利鋒、趙萬瑩、王麗娜，萘聯苯衍生物金屬離子螢光探針的製備及其識別檢測生物樣品或環境中Fe3+和/或Cu2+的套用。2013.4，中國，專利號：ZL201110169892.4。

公開專利

於明明、施冰傑、劉春霞、李占先、魏柳荷，一種線粒體靶向的pH敏感的比率型螢光探針及其製備方法和套用。2016.07.06，中國，申請號：CN201610221971.8

榮譽稱號

2014年和2016年年終考核被評為優秀；
2011年發表教改論文一篇（物理化學實驗教學的體會與思考）；
2016年發表教改論文一篇（高校全員育人的三級管理體系新探）；
2013、2014、2015和2016年化學學院高分子化學理論課網上教評均為優秀；
2013、2014和2015年藥學院物理化學理論課網上教評優秀；
2013、2014和2016年物理化學實驗課網上教評優秀；
2015年綜合化學實驗課網上教評優秀；
2013年和2014年兩次被評為平安校園工作先進個人，2015年被評為工會工作積極分子；
先後擔任2014級化學8班班主任和2016級化學1班班主任，作為2014級化學8班班主任2015年和2016年兩次被評為鄭州大學優秀班主任；

相關詞條

熱門詞條

聯絡我們